Details for: DRD3
Associated with
Cells (max top 100)
(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: amacrine cell (CL0000561)
Fold Change: 9.57
Marker Score: 30664 - Cell Name: Mueller cell (CL0000636)
Fold Change: 5.78
Marker Score: 8019 - Cell Name: progenitor cell (CL0011026)
Fold Change: 4.99
Marker Score: 32131 - Cell Name: retinal cone cell (CL0000573)
Fold Change: 3.94
Marker Score: 11299 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 3.16
Marker Score: 9019 - Cell Name: blood vessel endothelial cell (CL0000071)
Fold Change: 3.14
Marker Score: 3156 - Cell Name: OFF-bipolar cell (CL0000750)
Fold Change: 2.94
Marker Score: 8712 - Cell Name: ON-bipolar cell (CL0000749)
Fold Change: 2.58
Marker Score: 7516 - Cell Name: retinal bipolar neuron (CL0000748)
Fold Change: 2.5
Marker Score: 21127 - Cell Name: retina horizontal cell (CL0000745)
Fold Change: 2.35
Marker Score: 2252.5 - Cell Name: plasma cell (CL0000786)
Fold Change: 1.85
Marker Score: 2061 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 1.71
Marker Score: 3234 - Cell Name: erythrocyte (CL0000232)
Fold Change: 1.7
Marker Score: 940 - Cell Name: mural cell (CL0008034)
Fold Change: 1.48
Marker Score: 170230 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 1.29
Marker Score: 778 - Cell Name: kidney proximal convoluted tubule epithelial cell (CL1000838)
Fold Change: 1.13
Marker Score: 2345.5 - Cell Name: goblet cell (CL0000160)
Fold Change: 1.12
Marker Score: 7419 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71808 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48029 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30407 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2413 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.94
Marker Score: 5354 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.92
Marker Score: 2742 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5279 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.85
Marker Score: 1724 - Cell Name: double negative thymocyte (CL0002489)
Fold Change: 0.83
Marker Score: 1143 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1267 - Cell Name: megakaryocyte (CL0000556)
Fold Change: 0.77
Marker Score: 440 - Cell Name: brush cell (CL0002204)
Fold Change: 0.77
Marker Score: 706 - Cell Name: epithelial cell of alveolus of lung (CL0010003)
Fold Change: 0.76
Marker Score: 343 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.76
Marker Score: 394 - Cell Name: macrophage (CL0000235)
Fold Change: 0.76
Marker Score: 845 - Cell Name: stromal cell (CL0000499)
Fold Change: 0.7
Marker Score: 824 - Cell Name: hematopoietic stem cell (CL0000037)
Fold Change: 0.69
Marker Score: 362 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.67
Marker Score: 10434.5 - Cell Name: myeloid cell (CL0000763)
Fold Change: 0.62
Marker Score: 997 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.58
Marker Score: 464 - Cell Name: renal beta-intercalated cell (CL0002201)
Fold Change: 0.58
Marker Score: 184 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 0.56
Marker Score: 293 - Cell Name: mast cell (CL0000097)
Fold Change: 0.47
Marker Score: 270 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 0.46
Marker Score: 276 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.45
Marker Score: 141 - Cell Name: renal principal cell (CL0005009)
Fold Change: 0.43
Marker Score: 333.5 - Cell Name: neuronal receptor cell (CL0000006)
Fold Change: 0.36
Marker Score: 161 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.32
Marker Score: 155 - Cell Name: B cell (CL0000236)
Fold Change: 0.32
Marker Score: 308 - Cell Name: parietal epithelial cell (CL1000452)
Fold Change: 0.3
Marker Score: 110 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.28
Marker Score: 187 - Cell Name: pericyte (CL0000669)
Fold Change: 0.28
Marker Score: 163 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.26
Marker Score: 610 - Cell Name: endothelial cell of lymphatic vessel (CL0002138)
Fold Change: 0.25
Marker Score: 155 - Cell Name: retinal pigment epithelial cell (CL0002586)
Fold Change: 0.24
Marker Score: 71 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 0.24
Marker Score: 100 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.23
Marker Score: 75 - Cell Name: podocyte (CL0000653)
Fold Change: 0.21
Marker Score: 79 - Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
Fold Change: 0.2
Marker Score: 44 - Cell Name: astrocyte (CL0000127)
Fold Change: 0.2
Marker Score: 170 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 0.19
Marker Score: 49 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 0.18
Marker Score: 1408.5 - Cell Name: endothelial cell (CL0000115)
Fold Change: 0.18
Marker Score: 158 - Cell Name: bronchial epithelial cell (CL0002328)
Fold Change: 0.17
Marker Score: 45 - Cell Name: melanocyte (CL0000148)
Fold Change: 0.17
Marker Score: 68 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 0.17
Marker Score: 2208.5 - Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 0.16
Marker Score: 81 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 0.16
Marker Score: 43 - Cell Name: glial cell (CL0000125)
Fold Change: 0.15
Marker Score: 170 - Cell Name: ciliated epithelial cell (CL0000067)
Fold Change: 0.15
Marker Score: 70 - Cell Name: fibroblast (CL0000057)
Fold Change: 0.15
Marker Score: 146 - Cell Name: skin fibroblast (CL0002620)
Fold Change: 0.15
Marker Score: 39 - Cell Name: neuron (CL0000540)
Fold Change: 0.15
Marker Score: 604 - Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
Fold Change: 0.14
Marker Score: 145 - Cell Name: smooth muscle cell (CL0000192)
Fold Change: 0.14
Marker Score: 93 - Cell Name: mesothelial cell of epicardium (CL0011019)
Fold Change: 0.14
Marker Score: 45 - Cell Name: S cone cell (CL0003050)
Fold Change: 0.14
Marker Score: 42 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 0.14
Marker Score: 44 - Cell Name: fast muscle cell (CL0000190)
Fold Change: 0.14
Marker Score: 41 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 0.13
Marker Score: 164 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 0.13
Marker Score: 162 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 0.13
Marker Score: 43 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 0.13
Marker Score: 40 - Cell Name: innate lymphoid cell (CL0001065)
Fold Change: 0.13
Marker Score: 45 - Cell Name: T cell (CL0000084)
Fold Change: 0.12
Marker Score: 213 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.12
Marker Score: 516 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 0.12
Marker Score: 30 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 0.12
Marker Score: 413.5 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.11
Marker Score: 44 - Cell Name: type A enteroendocrine cell (CL0002067)
Fold Change: 0.11
Marker Score: 46 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: 0.11
Marker Score: 43 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 0.11
Marker Score: 170 - Cell Name: monocyte (CL0000576)
Fold Change: 0.11
Marker Score: 141 - Cell Name: Schwann cell (CL0002573)
Fold Change: 0.11
Marker Score: 37.5 - Cell Name: lymphocyte (CL0000542)
Fold Change: 0.11
Marker Score: 54 - Cell Name: subcutaneous fat cell (CL0002521)
Fold Change: 0.11
Marker Score: 39 - Cell Name: mesothelial cell (CL0000077)
Fold Change: 0.1
Marker Score: 42 - Cell Name: endothelial cell of artery (CL1000413)
Fold Change: 0.1
Marker Score: 43 - Cell Name: basal cell of epidermis (CL0002187)
Fold Change: 0.1
Marker Score: 45 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.1
Marker Score: 595 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: 0.1
Marker Score: 56 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.1
Marker Score: 28 - Cell Name: dendritic cell (CL0000451)
Fold Change: 0.09
Marker Score: 64
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Other Information
Genular Protein ID: 46117005
Symbol: DRD3_HUMAN
Name: Dopamine D3 receptor
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2129115
Title: Gene cloning of human dopaminergic D3 receptor and identification of its chromosome.
PubMed ID: 2129115
PubMed ID: 8415635
Title: Selective loss of dopamine D3-type receptor mRNA expression in parietal and motor cortices of patients with chronic schizophrenia.
PubMed ID: 8415635
PubMed ID: 7961889
Title: On the origin of mRNA encoding the truncated dopamine D3-type receptor D3nf and detection of D3nf-like immunoreactivity in human brain.
PubMed ID: 7961889
PubMed ID: 16641997
Title: The DNA sequence, annotation and analysis of human chromosome 3.
PubMed ID: 16641997
DOI: 10.1038/nature04728
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 1362221
Title: Association between schizophrenia and homozygosity at the dopamine D3 receptor gene.
PubMed ID: 1362221
PubMed ID: 9514583
Title: European multicentre association study of schizophrenia: a study of the DRD2 Ser311Cys and DRD3 Ser9Gly polymorphisms.
PubMed ID: 9514583
DOI: 10.1002/(sici)1096-8628(19980207)81:1<24::aid-ajmg5>3.0.co;2-n
PubMed ID: 16386234
Title: Paralemmin interacts with D3 dopamine receptors: implications for membrane localization and cAMP signaling.
PubMed ID: 16386234
PubMed ID: 19520868
Title: G protein-coupled receptor kinase 4 (GRK4) regulates the phosphorylation and function of the dopamine D3 receptor.
PubMed ID: 19520868
PubMed ID: 26460884
Title: G Protein-Coupled Receptors Directly Bind Filamin A with High Affinity and Promote Filamin Phosphorylation.
PubMed ID: 26460884
PubMed ID: 27659709
Title: Palmitoylation of the carboxyl-terminal tail of dopamine D4 receptor is required for surface expression, endocytosis, and signaling.
PubMed ID: 27659709
PubMed ID: 21097933
Title: Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist.
PubMed ID: 21097933
PubMed ID: 9034004
Title: Further evidence of no association between Ser9Gly polymorphism of dopamine D3 receptor gene and schizophrenia.
PubMed ID: 9034004
DOI: 10.1002/(sici)1096-8628(19970221)74:1<40::aid-ajmg9>3.0.co;2-z
PubMed ID: 10391209
Title: Characterization of single-nucleotide polymorphisms in coding regions of human genes.
PubMed ID: 10391209
DOI: 10.1038/10290
PubMed ID: 16650084
Title: Linkage with the Ser9Gly DRD3 polymorphism in essential tremor families.
PubMed ID: 16650084
PubMed ID: 16809426
Title: A functional variant of the dopamine D3 receptor is associated with risk and age-at-onset of essential tremor.
PubMed ID: 16809426
Sequence Information:
- Length: 400
- Mass: 44195
- Checksum: 3E8426597D6C164D
- Sequence:
MASLSQLSGH LNYTCGAENS TGASQARPHA YYALSYCALI LAIVFGNGLV CMAVLKERAL QTTTNYLVVS LAVADLLVAT LVMPWVVYLE VTGGVWNFSR ICCDVFVTLD VMMCTASILN LCAISIDRYT AVVMPVHYQH GTGQSSCRRV ALMITAVWVL AFAVSCPLLF GFNTTGDPTV CSISNPDFVI YSSVVSFYLP FGVTVLVYAR IYVVLKQRRR KRILTRQNSQ CNSVRPGFPQ QTLSPDPAHL ELKRYYSICQ DTALGGPGFQ ERGGELKREE KTRNSLSPTI APKLSLEVRK LSNGRLSTSL KLGPLQPRGV PLREKKATQM VAIVLGAFIV CWLPFFLTHV LNTHCQTCHV SPELYSATTW LGYVNSALNP VIYTTFNIEF RKAFLKILSC
Genular Protein ID: 141078141
Symbol: A8K8E4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 400
- Mass: 44197
- Checksum: 2CC5609A703895DD
- Sequence:
MASLSQLSSH LNYTCGAENS TGASQARPHA YYALSYCALI LAIVFGNGLV CMAVLKERAL QTTTNYLVVS LAVADLLVAT LVMPWVVYLE VTGGVWNFSR ICCDVFVTLD VMMCTASILN LCAISIDRYT AVVMPVHYQH GTGQSSCRRV ALMITAVWVL AFAVSCPLLF GFNTTGDPTV CSISNPDFVI YSSVVSFYLP FGVTVLVYAR IYVALKQRRR KRILTRQNSQ CNSVRPGFPQ QTLSPDPAHL ELKRYYSICQ DTALGGPGFQ ERGGELKREE KTRNSLSPTI APKLSLEVRK LSNGRLSTSL KLGPLQPRGV PLREKKATQM VAIVLGAFIV CWLPFFLTHV LNTHCQTCHV SPELYSATTW LGYVNSALNP VIYTTFNIEF RKAFLKILSC
Genular Protein ID: 699198437
Symbol: A1A4V4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 400
- Mass: 44220
- Checksum: F5FAA7FDC60FA289
- Sequence:
MASLSQLSSH LNYTCGAENS TGASQARPHA YYALSYCALI LAIVFGNGLV CMAVLKERAL QTTTNYLVVS LAVADLLVAT LVMPWVVYLE VTGGVWNFSH ICCDVFVTLD VMMCTASILN LCAISIDRYT AVVMPVHYQH GTGQSSCRRV ALMITAVWVL AFAVSCPLLF GFNTTGDPTV CSISNPDFVI YSSVVSFYLP FGVTVLVYAR IYEVLKQRRR KRILTRQNSQ CNSVRPGFPQ QTLSPDPAHL ELKRYYSICQ DTALGGPGFQ ERGGELKREE KTRNSLSPTI APKLSLEVRK LSNGRLSTSL KLGPPQPRGV PLREKKATQM VAIVLGAFIV CWLPFFLTHV LNTHCQTCHV SPELYSATTW LGYVNSALNP VIYTTFNIEF RKAFLKILSC
Genular Protein ID: 4222405301
Symbol: E9PCM4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 16641997
Title: The DNA sequence, annotation and analysis of human chromosome 3.
PubMed ID: 16641997
DOI: 10.1038/nature04728
Sequence Information:
- Length: 367
- Mass: 40730
- Checksum: 8910659CBD73CFE8
- Sequence:
MASLSQLSGH LNYTCGAENS TGASQARPHA YYALSYCALI LAIVFGNGLV CMAVLKERAL QTTTNYLVVS LAVADLLVAT LVMPWVVYLE VTGGVWNFSR ICCDVFVTLD VMMCTASILN LCAISIDRYT AVVMPVHYQH GTGQSSCRRV ALMITAVWVL AFAVSCPLLF GFNTTGDPTV CSISNPDFVI YSSVVSFYLP FGVTVLVYAR IYVVLKQRRR KRILTRQNSQ CNSVRPGFPQ QTLSPDPAHL ELKRYYSICQ DTALGGPGFQ ERGGELKREE KTRNSLMPLR EKKATQMVAI VLGAFIVCWL PFFLTHVLNT HCQTCHVSPE LYSATTWLGY VNSALNPVIY TTFNIEFRKA FLKILSC
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.