Details for: DRD3

Gene ID: 1814

Symbol: DRD3

Ensembl ID: ENSG00000151577

Description: dopamine receptor D3

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 1.3124
    Cell Significance Index: 31.7900
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 1.0065
    Cell Significance Index: 17.2100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.7051
    Cell Significance Index: 31.1900
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: 0.6890
    Cell Significance Index: 10.0400
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.6462
    Cell Significance Index: 24.4700
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 0.5701
    Cell Significance Index: 3.0000
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.5031
    Cell Significance Index: 6.5100
  • Cell Name: progenitor cell (CL0011026)
    Fold Change: 0.3238
    Cell Significance Index: 3.4400
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.2258
    Cell Significance Index: 3.8700
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: 0.1667
    Cell Significance Index: 2.7000
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.0667
    Cell Significance Index: 0.8000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0479
    Cell Significance Index: 33.1500
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 0.0418
    Cell Significance Index: 0.8500
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 0.0345
    Cell Significance Index: 1.0900
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 0.0303
    Cell Significance Index: 0.3900
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.0142
    Cell Significance Index: 0.2100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0121
    Cell Significance Index: 2.4300
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 0.0118
    Cell Significance Index: 0.0800
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.0106
    Cell Significance Index: 0.1100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0056
    Cell Significance Index: 10.5700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.0051
    Cell Significance Index: 0.7400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0024
    Cell Significance Index: 3.7000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0020
    Cell Significance Index: 0.4000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0019
    Cell Significance Index: 3.5600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0018
    Cell Significance Index: 2.4500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0014
    Cell Significance Index: 0.8700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0013
    Cell Significance Index: 0.4700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0004
    Cell Significance Index: 0.0800
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0021
    Cell Significance Index: -0.0300
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0031
    Cell Significance Index: -2.3300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0032
    Cell Significance Index: -1.4300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0041
    Cell Significance Index: -2.3200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0053
    Cell Significance Index: -1.5300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0078
    Cell Significance Index: -0.2100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0083
    Cell Significance Index: -1.4900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0086
    Cell Significance Index: -0.2400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0109
    Cell Significance Index: -0.7300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0115
    Cell Significance Index: -1.5800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0121
    Cell Significance Index: -2.5500
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: -0.0141
    Cell Significance Index: -0.1500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0172
    Cell Significance Index: -1.3200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0183
    Cell Significance Index: -2.2500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0190
    Cell Significance Index: -1.2000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0209
    Cell Significance Index: -2.4000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0209
    Cell Significance Index: -2.1800
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0226
    Cell Significance Index: -0.5800
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.0237
    Cell Significance Index: -0.3600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0248
    Cell Significance Index: -0.7900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0262
    Cell Significance Index: -1.6100
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.0264
    Cell Significance Index: -0.2500
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: -0.0264
    Cell Significance Index: -0.3300
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0307
    Cell Significance Index: -0.6000
  • Cell Name: uterine smooth muscle cell (CL0002601)
    Fold Change: -0.0324
    Cell Significance Index: -0.3100
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0338
    Cell Significance Index: -1.1900
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.0351
    Cell Significance Index: -0.4100
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0378
    Cell Significance Index: -2.1200
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0413
    Cell Significance Index: -0.9100
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.0427
    Cell Significance Index: -0.7200
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0434
    Cell Significance Index: -1.4200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0451
    Cell Significance Index: -2.1200
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.0464
    Cell Significance Index: -1.1600
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0496
    Cell Significance Index: -1.0000
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.0496
    Cell Significance Index: -0.9700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0501
    Cell Significance Index: -1.7600
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: -0.0503
    Cell Significance Index: -0.6900
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0506
    Cell Significance Index: -1.0000
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.0518
    Cell Significance Index: -1.0200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0576
    Cell Significance Index: -1.6600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0582
    Cell Significance Index: -1.2600
  • Cell Name: fast muscle cell (CL0000190)
    Fold Change: -0.0596
    Cell Significance Index: -0.7800
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0597
    Cell Significance Index: -1.4900
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -0.0608
    Cell Significance Index: -0.7800
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: -0.0614
    Cell Significance Index: -0.8300
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0623
    Cell Significance Index: -0.9200
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0624
    Cell Significance Index: -1.3300
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: -0.0641
    Cell Significance Index: -0.9300
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.0652
    Cell Significance Index: -1.5900
  • Cell Name: cell of skeletal muscle (CL0000188)
    Fold Change: -0.0664
    Cell Significance Index: -0.8500
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.0680
    Cell Significance Index: -1.9400
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.0687
    Cell Significance Index: -1.1900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0696
    Cell Significance Index: -1.7400
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0699
    Cell Significance Index: -1.5100
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0706
    Cell Significance Index: -1.8000
  • Cell Name: acinar cell (CL0000622)
    Fold Change: -0.0713
    Cell Significance Index: -0.9000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0742
    Cell Significance Index: -1.9800
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0762
    Cell Significance Index: -1.5800
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.0791
    Cell Significance Index: -1.3300
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: -0.0795
    Cell Significance Index: -0.7100
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0801
    Cell Significance Index: -1.9200
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.0822
    Cell Significance Index: -1.7200
  • Cell Name: slow muscle cell (CL0000189)
    Fold Change: -0.0836
    Cell Significance Index: -1.2500
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0855
    Cell Significance Index: -2.4500
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: -0.0862
    Cell Significance Index: -1.0000
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.0892
    Cell Significance Index: -1.2700
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.0927
    Cell Significance Index: -1.1700
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.0949
    Cell Significance Index: -1.6400
  • Cell Name: stromal cell of endometrium (CL0002255)
    Fold Change: -0.0956
    Cell Significance Index: -1.3600
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.0970
    Cell Significance Index: -2.4200
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.0973
    Cell Significance Index: -1.3500
  • Cell Name: immature NK T cell (CL0000914)
    Fold Change: -0.0977
    Cell Significance Index: -1.2500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Structure:** DRD3 is a seven-transmembrane receptor, belonging to the class A/1 rhodopsin-like receptors. 2. **Binding:** It binds to dopamine, a neurotransmitter involved in various physiological processes, including movement, motivation, and cognition. 3. **Signaling:** DRD3 activates adenylate cyclase, leading to increased intracellular cAMP levels, and modulates various signaling pathways, including those involved in learning, memory, and social behavior. 4. **Expression:** DRD3 is expressed in numerous cell types, including neurons, glial cells, and endothelial cells, suggesting its involvement in various physiological and pathological processes. **Pathways and Functions:** 1. **Adenylate Cyclase-Activating Signaling:** DRD3 activation leads to the stimulation of adenylate cyclase, resulting in increased cAMP levels and modulation of downstream signaling pathways. 2. **G Protein-Coupled Receptor Signaling:** DRD3 interacts with G proteins, modulating the activity of adenylate cyclase and influencing various signaling pathways. 3. **Intracellular Calcium Ion Homeostasis:** DRD3 regulates intracellular calcium ion concentrations, influencing neuronal signaling and synaptic transmission. 4. **Neurotransmitter Regulation:** DRD3 modulates the release and uptake of dopamine, a neurotransmitter involved in various physiological processes, including movement, motivation, and cognition. 5. **Circadian Regulation:** DRD3 expression is influenced by the circadian clock, highlighting its role in regulating physiological processes in a time-dependent manner. **Clinical Significance:** 1. **Neurological Disorders:** DRD3 has been implicated in various neurological disorders, including Parkinson's disease, schizophrenia, and attention-deficit/hyperactivity disorder (ADHD). 2. **Immunological Disorders:** DRD3 has been linked to immunological disorders, including multiple sclerosis and rheumatoid arthritis, suggesting its role in modulating immune responses. 3. **Cancer:** DRD3 has been found to be overexpressed in certain types of cancer, including breast and lung cancer, highlighting its potential as a therapeutic target. 4. **Psychological Disorders:** DRD3 has been implicated in psychological disorders, including depression and anxiety, suggesting its role in modulating mood regulation and emotional responses. In conclusion, the dopamine receptor D3 (DRD3) is a multifaceted receptor with significant implications for immunological and neurological processes. Its role in modulating signaling pathways, neurotransmitter regulation, and intracellular calcium ion homeostasis highlights its importance in various physiological and pathological contexts. Further research is needed to fully elucidate the functions and clinical significance of DRD3, but its current understanding suggests its potential as a therapeutic target for a range of diseases.

Genular Protein ID: 46117005

Symbol: DRD3_HUMAN

Name: Dopamine D3 receptor

UniProtKB Accession Codes:

P35462 A1A4V5 Q4VBM8

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChEBI 3 ChEMBL 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 53 DrugCentral 1 EMBL 7 EMDB 3 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 40 Gene3D 1 GeneCards 1 GeneTree 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 5 MINT 1 MalaCards 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 4 PIR 3 PRINTS 3 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RNAct 1 Reactome 2 RefSeq 5 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 2129115

Title: Gene cloning of human dopaminergic D3 receptor and identification of its chromosome.

PubMed ID: 2129115

PubMed ID: 8415635

Title: Selective loss of dopamine D3-type receptor mRNA expression in parietal and motor cortices of patients with chronic schizophrenia.

PubMed ID: 8415635

DOI: 10.1073/pnas.90.19.8942

PubMed ID: 7961889

Title: On the origin of mRNA encoding the truncated dopamine D3-type receptor D3nf and detection of D3nf-like immunoreactivity in human brain.

PubMed ID: 7961889

DOI: 10.1016/s0021-9258(19)62033-8

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1362221

Title: Association between schizophrenia and homozygosity at the dopamine D3 receptor gene.

PubMed ID: 1362221

DOI: 10.1136/jmg.29.12.858

PubMed ID: 9514583

Title: European multicentre association study of schizophrenia: a study of the DRD2 Ser311Cys and DRD3 Ser9Gly polymorphisms.

PubMed ID: 9514583

DOI: 10.1002/(sici)1096-8628(19980207)81:1<24::aid-ajmg5>3.0.co;2-n

PubMed ID: 16386234

Title: Paralemmin interacts with D3 dopamine receptors: implications for membrane localization and cAMP signaling.

PubMed ID: 16386234

DOI: 10.1016/j.abb.2005.10.027

PubMed ID: 19520868

Title: G protein-coupled receptor kinase 4 (GRK4) regulates the phosphorylation and function of the dopamine D3 receptor.

PubMed ID: 19520868

DOI: 10.1074/jbc.m109.003665

PubMed ID: 26460884

Title: G Protein-Coupled Receptors Directly Bind Filamin A with High Affinity and Promote Filamin Phosphorylation.

PubMed ID: 26460884

DOI: 10.1021/acs.biochem.5b00975

PubMed ID: 27659709

Title: Palmitoylation of the carboxyl-terminal tail of dopamine D4 receptor is required for surface expression, endocytosis, and signaling.

PubMed ID: 27659709

DOI: 10.1016/j.bbrc.2016.09.094

PubMed ID: 21097933

Title: Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist.

PubMed ID: 21097933

DOI: 10.1126/science.1197410

PubMed ID: 9034004

Title: Further evidence of no association between Ser9Gly polymorphism of dopamine D3 receptor gene and schizophrenia.

PubMed ID: 9034004

DOI: 10.1002/(sici)1096-8628(19970221)74:1<40::aid-ajmg9>3.0.co;2-z

PubMed ID: 10391209

Title: Characterization of single-nucleotide polymorphisms in coding regions of human genes.

PubMed ID: 10391209

DOI: 10.1038/10290

PubMed ID: 16650084

Title: Linkage with the Ser9Gly DRD3 polymorphism in essential tremor families.

PubMed ID: 16650084

DOI: 10.1111/j.1399-0004.2006.00600.x

PubMed ID: 16809426

Title: A functional variant of the dopamine D3 receptor is associated with risk and age-at-onset of essential tremor.

PubMed ID: 16809426

DOI: 10.1073/pnas.0508189103

Sequence Information:

  • Length: 400
  • Mass: 44195
  • Checksum: 3E8426597D6C164D
  • Sequence:
    • MASLSQLSGH LNYTCGAENS TGASQARPHA YYALSYCALI LAIVFGNGLV CMAVLKERAL 
QTTTNYLVVS LAVADLLVAT LVMPWVVYLE VTGGVWNFSR ICCDVFVTLD VMMCTASILN 
LCAISIDRYT AVVMPVHYQH GTGQSSCRRV ALMITAVWVL AFAVSCPLLF GFNTTGDPTV 
CSISNPDFVI YSSVVSFYLP FGVTVLVYAR IYVVLKQRRR KRILTRQNSQ CNSVRPGFPQ 
QTLSPDPAHL ELKRYYSICQ DTALGGPGFQ ERGGELKREE KTRNSLSPTI APKLSLEVRK 
LSNGRLSTSL KLGPLQPRGV PLREKKATQM VAIVLGAFIV CWLPFFLTHV LNTHCQTCHV 
SPELYSATTW LGYVNSALNP VIYTTFNIEF RKAFLKILSC

Genular Protein ID: 141078141

Symbol: A8K8E4_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K8E4

Database IDs:

ARBA 13 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 11 Gene3D 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 3 PROSITE 3 Pfam 1 RefSeq 4 RuleBase 1 SAM 1 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 400
  • Mass: 44197
  • Checksum: 2CC5609A703895DD
  • Sequence:
    • MASLSQLSSH LNYTCGAENS TGASQARPHA YYALSYCALI LAIVFGNGLV CMAVLKERAL 
QTTTNYLVVS LAVADLLVAT LVMPWVVYLE VTGGVWNFSR ICCDVFVTLD VMMCTASILN 
LCAISIDRYT AVVMPVHYQH GTGQSSCRRV ALMITAVWVL AFAVSCPLLF GFNTTGDPTV 
CSISNPDFVI YSSVVSFYLP FGVTVLVYAR IYVALKQRRR KRILTRQNSQ CNSVRPGFPQ 
QTLSPDPAHL ELKRYYSICQ DTALGGPGFQ ERGGELKREE KTRNSLSPTI APKLSLEVRK 
LSNGRLSTSL KLGPLQPRGV PLREKKATQM VAIVLGAFIV CWLPFFLTHV LNTHCQTCHV 
SPELYSATTW LGYVNSALNP VIYTTFNIEF RKAFLKILSC

Genular Protein ID: 4222405301

Symbol: E9PCM4_HUMAN

Name: N/A

UniProtKB Accession Codes:

E9PCM4

Database IDs:

ARBA 13 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 5 Gene3D 1 HGNC 1 HOGENOM 1 InterPro 4 NCBI Taxonomy 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRINTS 3 PROSITE 3 Pfam 1 Proteomes 2 RefSeq 1 RuleBase 1 SAM 1 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

Sequence Information:

  • Length: 367
  • Mass: 40730
  • Checksum: 8910659CBD73CFE8
  • Sequence:
    • MASLSQLSGH LNYTCGAENS TGASQARPHA YYALSYCALI LAIVFGNGLV CMAVLKERAL 
QTTTNYLVVS LAVADLLVAT LVMPWVVYLE VTGGVWNFSR ICCDVFVTLD VMMCTASILN 
LCAISIDRYT AVVMPVHYQH GTGQSSCRRV ALMITAVWVL AFAVSCPLLF GFNTTGDPTV 
CSISNPDFVI YSSVVSFYLP FGVTVLVYAR IYVVLKQRRR KRILTRQNSQ CNSVRPGFPQ 
QTLSPDPAHL ELKRYYSICQ DTALGGPGFQ ERGGELKREE KTRNSLMPLR EKKATQMVAI 
VLGAFIVCWL PFFLTHVLNT HCQTCHVSPE LYSATTWLGY VNSALNPVIY TTFNIEFRKA 
FLKILSC

Genular Protein ID: 699198437

Symbol: A1A4V4_HUMAN

Name: N/A

UniProtKB Accession Codes:

A1A4V4

Database IDs:

ARBA 13 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 11 Gene3D 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 3 PROSITE 3 Pfam 1 RefSeq 1 RuleBase 1 SAM 1 SMART 1 SMR 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 400
  • Mass: 44220
  • Checksum: F5FAA7FDC60FA289
  • Sequence:
    • MASLSQLSSH LNYTCGAENS TGASQARPHA YYALSYCALI LAIVFGNGLV CMAVLKERAL 
QTTTNYLVVS LAVADLLVAT LVMPWVVYLE VTGGVWNFSH ICCDVFVTLD VMMCTASILN 
LCAISIDRYT AVVMPVHYQH GTGQSSCRRV ALMITAVWVL AFAVSCPLLF GFNTTGDPTV 
CSISNPDFVI YSSVVSFYLP FGVTVLVYAR IYEVLKQRRR KRILTRQNSQ CNSVRPGFPQ 
QTLSPDPAHL ELKRYYSICQ DTALGGPGFQ ERGGELKREE KTRNSLSPTI APKLSLEVRK 
LSNGRLSTSL KLGPPQPRGV PLREKKATQM VAIVLGAFIV CWLPFFLTHV LNTHCQTCHV 
SPELYSATTW LGYVNSALNP VIYTTFNIEF RKAFLKILSC

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.