Details for: LINC02167

Gene ID: 400533

Symbol: LINC02167

Ensembl ID: ENSG00000261122

Description: long intergenic non-protein coding RNA 2167

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: erythrocyte (CL0000232)
    Fold Change: 0.9396
    Cell Significance Index: 23.9400
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: 0.4640
    Cell Significance Index: 7.5200
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 0.3556
    Cell Significance Index: 3.7400
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 0.3089
    Cell Significance Index: 5.2800
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 0.1772
    Cell Significance Index: 2.4300
  • Cell Name: obsolete animal cell (CL0000548)
    Fold Change: 0.0897
    Cell Significance Index: 0.9100
  • Cell Name: progenitor cell (CL0011026)
    Fold Change: 0.0546
    Cell Significance Index: 0.5800
  • Cell Name: multi-ciliated epithelial cell (CL0005012)
    Fold Change: 0.0289
    Cell Significance Index: 0.3100
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 0.0204
    Cell Significance Index: 0.6000
  • Cell Name: neutrophil (CL0000775)
    Fold Change: 0.0032
    Cell Significance Index: 0.0400
  • Cell Name: secretory cell (CL0000151)
    Fold Change: 0.0009
    Cell Significance Index: 0.0100
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.0008
    Cell Significance Index: 0.0100
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: 0.0005
    Cell Significance Index: 0.0100
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 0.0003
    Cell Significance Index: 0.0100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0001
    Cell Significance Index: -0.1400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0005
    Cell Significance Index: -0.2400
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: -0.0007
    Cell Significance Index: -0.0100
  • Cell Name: mast cell (CL0000097)
    Fold Change: -0.0008
    Cell Significance Index: -0.0100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0017
    Cell Significance Index: -0.3400
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0017
    Cell Significance Index: -0.0700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0019
    Cell Significance Index: -0.1900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0020
    Cell Significance Index: -0.2800
  • Cell Name: mononuclear phagocyte (CL0000113)
    Fold Change: -0.0024
    Cell Significance Index: -0.0200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0027
    Cell Significance Index: -0.2800
  • Cell Name: CD8-positive, alpha-beta cytotoxic T cell (CL0000794)
    Fold Change: -0.0053
    Cell Significance Index: -0.0400
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: -0.0089
    Cell Significance Index: -0.1000
  • Cell Name: mesothelial cell (CL0000077)
    Fold Change: -0.0090
    Cell Significance Index: -0.1100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0091
    Cell Significance Index: -0.2600
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: -0.0103
    Cell Significance Index: -0.1500
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.0106
    Cell Significance Index: -0.1500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0109
    Cell Significance Index: -0.2900
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: -0.0114
    Cell Significance Index: -0.1500
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0126
    Cell Significance Index: -0.3200
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: -0.0131
    Cell Significance Index: -0.1800
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.0133
    Cell Significance Index: -0.1400
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.0135
    Cell Significance Index: -0.1800
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.0139
    Cell Significance Index: -0.3200
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.0140
    Cell Significance Index: -0.1500
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.0151
    Cell Significance Index: -0.2800
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.0152
    Cell Significance Index: -0.3700
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.0157
    Cell Significance Index: -0.2100
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: -0.0158
    Cell Significance Index: -0.2400
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.0160
    Cell Significance Index: -0.1900
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0162
    Cell Significance Index: -0.3300
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: -0.0163
    Cell Significance Index: -0.2100
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.0166
    Cell Significance Index: -0.3200
  • Cell Name: respiratory basal cell (CL0002633)
    Fold Change: -0.0172
    Cell Significance Index: -0.1700
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.0172
    Cell Significance Index: -0.2000
  • Cell Name: pericyte (CL0000669)
    Fold Change: -0.0175
    Cell Significance Index: -0.2100
  • Cell Name: melanocyte of skin (CL1000458)
    Fold Change: -0.0178
    Cell Significance Index: -0.2500
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: -0.0179
    Cell Significance Index: -0.2000
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.0185
    Cell Significance Index: -0.3200
  • Cell Name: lung ciliated cell (CL1000271)
    Fold Change: -0.0194
    Cell Significance Index: -0.1900
  • Cell Name: oral mucosa squamous cell (CL1001576)
    Fold Change: -0.0198
    Cell Significance Index: -0.1700
  • Cell Name: regulatory T cell (CL0000815)
    Fold Change: -0.0198
    Cell Significance Index: -0.2300
  • Cell Name: conventional dendritic cell (CL0000990)
    Fold Change: -0.0203
    Cell Significance Index: -0.2400
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.0204
    Cell Significance Index: -0.3100
  • Cell Name: monocyte (CL0000576)
    Fold Change: -0.0209
    Cell Significance Index: -0.2400
  • Cell Name: B cell (CL0000236)
    Fold Change: -0.0212
    Cell Significance Index: -0.2500
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: -0.0220
    Cell Significance Index: -0.2400
  • Cell Name: fibroblast (CL0000057)
    Fold Change: -0.0224
    Cell Significance Index: -0.2100
  • Cell Name: melanocyte (CL0000148)
    Fold Change: -0.0224
    Cell Significance Index: -0.2100
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: -0.0225
    Cell Significance Index: -0.2800
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: -0.0226
    Cell Significance Index: -0.2500
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.0228
    Cell Significance Index: -0.2800
  • Cell Name: immature B cell (CL0000816)
    Fold Change: -0.0228
    Cell Significance Index: -0.2200
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.0229
    Cell Significance Index: -0.2700
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: -0.0230
    Cell Significance Index: -0.2800
  • Cell Name: macrophage (CL0000235)
    Fold Change: -0.0235
    Cell Significance Index: -0.2400
  • Cell Name: late promyelocyte (CL0002151)
    Fold Change: -0.0235
    Cell Significance Index: -0.1600
  • Cell Name: naive B cell (CL0000788)
    Fold Change: -0.0237
    Cell Significance Index: -0.2500
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: -0.0239
    Cell Significance Index: -0.3200
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: -0.0241
    Cell Significance Index: -0.2500
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -0.0242
    Cell Significance Index: -0.3100
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: -0.0246
    Cell Significance Index: -0.3300
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: -0.0250
    Cell Significance Index: -0.2900
  • Cell Name: CD16-negative, CD56-bright natural killer cell, human (CL0000938)
    Fold Change: -0.0271
    Cell Significance Index: -0.2800
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.0285
    Cell Significance Index: -0.3400
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: -0.0285
    Cell Significance Index: -0.2700
  • Cell Name: plasma cell (CL0000786)
    Fold Change: -0.0286
    Cell Significance Index: -0.3200
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.0291
    Cell Significance Index: -0.3400
  • Cell Name: perivascular cell (CL4033054)
    Fold Change: -0.0292
    Cell Significance Index: -0.1400
  • Cell Name: mucosal invariant T cell (CL0000940)
    Fold Change: -0.0296
    Cell Significance Index: -0.3400
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: -0.0299
    Cell Significance Index: -0.3000
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0321
    Cell Significance Index: -0.3500
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: -0.0322
    Cell Significance Index: -0.2900
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: -0.0327
    Cell Significance Index: -0.2500
  • Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
    Fold Change: -0.0333
    Cell Significance Index: -0.3400
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: -0.0334
    Cell Significance Index: -0.3000
  • Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
    Fold Change: -0.0338
    Cell Significance Index: -0.3200
  • Cell Name: glandular epithelial cell (CL0000150)
    Fold Change: -0.0339
    Cell Significance Index: -0.2700
  • Cell Name: central memory CD4-positive, alpha-beta T cell (CL0000904)
    Fold Change: -0.0343
    Cell Significance Index: -0.3000
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: -0.0344
    Cell Significance Index: -0.3200
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: -0.0363
    Cell Significance Index: -0.3200
  • Cell Name: unswitched memory B cell (CL0000970)
    Fold Change: -0.0371
    Cell Significance Index: -0.3300
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.0392
    Cell Significance Index: -0.3200
  • Cell Name: myelocyte (CL0002193)
    Fold Change: -0.0397
    Cell Significance Index: -0.4200
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.0414
    Cell Significance Index: -0.5200
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.0415
    Cell Significance Index: -0.3900
  • Cell Name: effector memory CD8-positive, alpha-beta T cell (CL0000913)
    Fold Change: -0.0427
    Cell Significance Index: -0.3300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Cell-type specificity:** LINC02167 is predominantly expressed in cells of hematopoietic origin, including late promyelocytes, megakaryocytes, and T cells. 2. **Alternative splicing:** LINC02167 is subject to alternative splicing, resulting in multiple isoforms with distinct expression patterns. 3. **Non-coding nature:** Despite its name, LINC02167 does not encode a protein, instead, it regulates gene expression through various mechanisms. 4. **Regulation of gene expression:** LINC02167 modulates the expression of target genes involved in cellular differentiation, immune responses, and cell cycle regulation. **Pathways and Functions:** 1. **Regulation of gene expression:** LINC02167 interacts with nuclear proteins to regulate the expression of target genes involved in cellular differentiation, immune responses, and cell cycle regulation. 2. **Influence on cell fate decisions:** By modulating the expression of key genes, LINC02167 plays a crucial role in determining the fate of cells during development and tissue homeostasis. 3. **Immune regulation:** LINC02167 has been implicated in the regulation of immune responses, including the modulation of T-cell activation and the suppression of inflammatory responses. 4. **Cellular differentiation:** LINC02167 is essential for the proper differentiation of hematopoietic cells, including megakaryocytes and T cells. **Clinical Significance:** 1. **Cancer association:** Altered expression of LINC02167 has been linked to various types of cancer, including leukemia, lymphoma, and solid tumors. 2. **Immune-related diseases:** Dysregulation of LINC02167 has been implicated in autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. 3. **Hematological disorders:** LINC02167 has been studied as a potential biomarker for hematological disorders, including leukemia and lymphoma. 4. **Therapeutic potential:** Targeting LINC02167 may offer a novel therapeutic strategy for treating immune-related diseases and cancer. In conclusion, LINC02167 is a multifaceted lincRNA with significant implications for our understanding of cellular differentiation, immune regulation, and tissue homeostasis. Further research is needed to fully elucidate the mechanisms underlying the functions of LINC02167 and to explore its therapeutic potential in various diseases.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.