Details for: LOC101927993

Gene ID: 101927993

Symbol: LOC101927993

Ensembl ID: ENSG00000223446

Description: uncharacterized LOC101927993

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.2070
    Cell Significance Index: 3.0100
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: 0.0937
    Cell Significance Index: 1.3000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0732
    Cell Significance Index: 2.1100
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: 0.0631
    Cell Significance Index: 0.6100
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.0592
    Cell Significance Index: 0.7500
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 0.0489
    Cell Significance Index: 0.5100
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.0421
    Cell Significance Index: 0.5000
  • Cell Name: glandular cell of esophagus (CL0002657)
    Fold Change: 0.0345
    Cell Significance Index: 0.3700
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 0.0331
    Cell Significance Index: 0.4100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0318
    Cell Significance Index: 0.6900
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.0251
    Cell Significance Index: 0.5200
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: 0.0207
    Cell Significance Index: 0.2900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0180
    Cell Significance Index: 2.3100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0179
    Cell Significance Index: 1.1300
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: 0.0168
    Cell Significance Index: 0.1900
  • Cell Name: basophil mast progenitor cell (CL0002028)
    Fold Change: 0.0142
    Cell Significance Index: 0.1200
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.0108
    Cell Significance Index: 0.2900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0084
    Cell Significance Index: 0.3800
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 0.0066
    Cell Significance Index: 0.2300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.0037
    Cell Significance Index: 0.1000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0033
    Cell Significance Index: 0.5900
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 0.0033
    Cell Significance Index: 0.0200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.0032
    Cell Significance Index: 0.3700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.0017
    Cell Significance Index: 0.4800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0014
    Cell Significance Index: 0.0500
  • Cell Name: naive regulatory T cell (CL0002677)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0002
    Cell Significance Index: -0.3300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0003
    Cell Significance Index: -0.0100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0003
    Cell Significance Index: -0.0400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0004
    Cell Significance Index: -0.0100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0005
    Cell Significance Index: -0.2900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0007
    Cell Significance Index: -0.4400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0013
    Cell Significance Index: -0.2600
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: -0.0014
    Cell Significance Index: -0.0200
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0016
    Cell Significance Index: -0.3100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0017
    Cell Significance Index: -0.2400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0026
    Cell Significance Index: -0.3200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0026
    Cell Significance Index: -0.3800
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.0026
    Cell Significance Index: -0.0500
  • Cell Name: neutrophil (CL0000775)
    Fold Change: -0.0040
    Cell Significance Index: -0.0500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0043
    Cell Significance Index: -0.2000
  • Cell Name: thymocyte (CL0000893)
    Fold Change: -0.0044
    Cell Significance Index: -0.0600
  • Cell Name: club cell (CL0000158)
    Fold Change: -0.0050
    Cell Significance Index: -0.0600
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0051
    Cell Significance Index: -0.0700
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: -0.0056
    Cell Significance Index: -0.0600
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0061
    Cell Significance Index: -0.1600
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: -0.0066
    Cell Significance Index: -0.0700
  • Cell Name: CD141-positive myeloid dendritic cell (CL0002394)
    Fold Change: -0.0066
    Cell Significance Index: -0.0700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0068
    Cell Significance Index: -0.3800
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0073
    Cell Significance Index: -0.0800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0074
    Cell Significance Index: -0.4800
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.0074
    Cell Significance Index: -0.0600
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.0076
    Cell Significance Index: -0.1000
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.0076
    Cell Significance Index: -0.1900
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: -0.0081
    Cell Significance Index: -0.0500
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0085
    Cell Significance Index: -0.2500
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.0091
    Cell Significance Index: -0.1300
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: -0.0099
    Cell Significance Index: -0.1600
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: -0.0101
    Cell Significance Index: -0.1200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0103
    Cell Significance Index: -0.2700
  • Cell Name: chondrocyte (CL0000138)
    Fold Change: -0.0104
    Cell Significance Index: -0.1200
  • Cell Name: adipocyte (CL0000136)
    Fold Change: -0.0105
    Cell Significance Index: -0.1400
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: -0.0108
    Cell Significance Index: -0.1400
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0110
    Cell Significance Index: -0.3600
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.0112
    Cell Significance Index: -0.1700
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.0114
    Cell Significance Index: -0.2100
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.0118
    Cell Significance Index: -0.1900
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.0120
    Cell Significance Index: -0.1600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0122
    Cell Significance Index: -0.3900
  • Cell Name: progenitor cell (CL0011026)
    Fold Change: -0.0122
    Cell Significance Index: -0.1300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0129
    Cell Significance Index: -0.3500
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: -0.0131
    Cell Significance Index: -0.1800
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: -0.0135
    Cell Significance Index: -0.1600
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0137
    Cell Significance Index: -0.3500
  • Cell Name: epithelial cell of lung (CL0000082)
    Fold Change: -0.0138
    Cell Significance Index: -0.1300
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: -0.0149
    Cell Significance Index: -0.1200
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.0150
    Cell Significance Index: -0.4400
  • Cell Name: neuroendocrine cell (CL0000165)
    Fold Change: -0.0150
    Cell Significance Index: -0.1900
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: -0.0157
    Cell Significance Index: -0.1800
  • Cell Name: granulocyte (CL0000094)
    Fold Change: -0.0158
    Cell Significance Index: -0.1900
  • Cell Name: promonocyte (CL0000559)
    Fold Change: -0.0159
    Cell Significance Index: -0.1700
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0162
    Cell Significance Index: -0.3500
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.0164
    Cell Significance Index: -0.3800
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0167
    Cell Significance Index: -0.3600
  • Cell Name: fast muscle cell (CL0000190)
    Fold Change: -0.0168
    Cell Significance Index: -0.2200
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: -0.0169
    Cell Significance Index: -0.1100
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.0176
    Cell Significance Index: -0.2500
  • Cell Name: mast cell (CL0000097)
    Fold Change: -0.0182
    Cell Significance Index: -0.2400
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: -0.0183
    Cell Significance Index: -0.2400
  • Cell Name: decidual natural killer cell, human (CL0002343)
    Fold Change: -0.0184
    Cell Significance Index: -0.1900
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: -0.0191
    Cell Significance Index: -0.2300
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.0194
    Cell Significance Index: -0.3300
  • Cell Name: tracheobronchial smooth muscle cell (CL0019019)
    Fold Change: -0.0194
    Cell Significance Index: -0.2000
  • Cell Name: common lymphoid progenitor (CL0000051)
    Fold Change: -0.0197
    Cell Significance Index: -0.2000
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: -0.0199
    Cell Significance Index: -0.3400
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.0199
    Cell Significance Index: -0.2100
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.0202
    Cell Significance Index: -0.2400
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: -0.0204
    Cell Significance Index: -0.1800
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.0206
    Cell Significance Index: -0.5000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Uncharacterized gene**: LOC101927993 is an uncharacterized gene, meaning its function and mechanism of action remain unknown. 2. **Widespread expression**: This gene is expressed in a diverse range of cell types, including oligodendrocyte precursor cells, microglial cells, blood vessel endothelial cells, granulocyte monocyte progenitor cells, goblet cells, intestinal crypt stem cells, early T lineage precursors, cerebral cortex GABAergic interneurons, forebrain radial glial cells, and absorptive cells. 3. **Lack of known orthologs**: There is no known ortholog of LOC101927993 in other species, suggesting a potentially unique function. 4. **Possible involvement in cellular differentiation**: The expression of LOC101927993 in oligodendrocyte precursor cells and cerebral cortex GABAergic interneurons suggests a potential role in cellular differentiation processes. **Pathways and Functions:** 1. **Cellular differentiation**: LOC101927993 may play a role in regulating cellular differentiation, particularly in the nervous system, where it is expressed in oligodendrocyte precursor cells and cerebral cortex GABAergic interneurons. 2. **Cell proliferation**: The expression of this gene in granulocyte monocyte progenitor cells and intestinal crypt stem cells suggests a potential role in regulating cell proliferation. 3. **Apoptosis**: LOC101927993 may also be involved in regulating apoptosis (programmed cell death) in various cell types, including microglial cells and blood vessel endothelial cells. 4. **Cell-cell interactions**: The expression of this gene in goblet cells and absorptive cells suggests a potential role in regulating cell-cell interactions and tissue homeostasis. **Clinical Significance:** 1. **Neurological disorders**: The expression of LOC101927993 in oligodendrocyte precursor cells and cerebral cortex GABAergic interneurons suggests a potential link to neurological disorders, such as multiple sclerosis or neurodegenerative diseases. 2. **Immunological disorders**: The expression of this gene in microglial cells and granulocyte monocyte progenitor cells suggests a potential link to immunological disorders, such as autoimmune diseases or inflammatory conditions. 3. **Cancer**: The expression of LOC101927993 in intestinal crypt stem cells and absorptive cells suggests a potential role in cancer development and progression, particularly in colorectal cancer. 4. **Tissue repair**: The expression of this gene in blood vessel endothelial cells and goblet cells suggests a potential role in tissue repair and regeneration. In conclusion, the uncharacterized gene LOC101927993 has emerged as a significant player in various cellular processes, including differentiation, proliferation, and survival. Further research is necessary to elucidate its function and mechanism of action, as well as its clinical significance in various diseases and disorders.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.