Details for: LINC02090

Gene ID: 105371562

Symbol: LINC02090

Ensembl ID: ENSG00000230969

Description: long intergenic non-protein coding RNA 2090

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: 0.6401
    Cell Significance Index: 9.3300
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: 0.5204
    Cell Significance Index: 6.3300
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.1492
    Cell Significance Index: 1.8900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.1005
    Cell Significance Index: 6.7600
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: 0.0898
    Cell Significance Index: 1.2600
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 0.0881
    Cell Significance Index: 1.0300
  • Cell Name: common dendritic progenitor (CL0001029)
    Fold Change: 0.0798
    Cell Significance Index: 0.8300
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.0203
    Cell Significance Index: 0.5800
  • Cell Name: stromal cell (CL0000499)
    Fold Change: -0.0010
    Cell Significance Index: -0.0100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0013
    Cell Significance Index: -0.5900
  • Cell Name: secretory cell (CL0000151)
    Fold Change: -0.0014
    Cell Significance Index: -0.0100
  • Cell Name: malignant cell (CL0001064)
    Fold Change: -0.0019
    Cell Significance Index: -0.0100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0028
    Cell Significance Index: -0.5600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0034
    Cell Significance Index: -0.4000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0071
    Cell Significance Index: -0.4600
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.0083
    Cell Significance Index: -0.2000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0109
    Cell Significance Index: -0.4800
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.0113
    Cell Significance Index: -0.2200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0127
    Cell Significance Index: -0.3400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0127
    Cell Significance Index: -0.5900
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: -0.0139
    Cell Significance Index: -0.1800
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: -0.0161
    Cell Significance Index: -0.2600
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.0165
    Cell Significance Index: -0.2800
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.0167
    Cell Significance Index: -0.4900
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: -0.0184
    Cell Significance Index: -0.2500
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0187
    Cell Significance Index: -0.4000
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0188
    Cell Significance Index: -0.4800
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: -0.0210
    Cell Significance Index: -0.2700
  • Cell Name: plasma cell (CL0000786)
    Fold Change: -0.0233
    Cell Significance Index: -0.2600
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.0238
    Cell Significance Index: -0.2800
  • Cell Name: conventional dendritic cell (CL0000990)
    Fold Change: -0.0262
    Cell Significance Index: -0.3100
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.0265
    Cell Significance Index: -0.2800
  • Cell Name: memory B cell (CL0000787)
    Fold Change: -0.0282
    Cell Significance Index: -0.3000
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0294
    Cell Significance Index: -0.5900
  • Cell Name: early lymphoid progenitor (CL0000936)
    Fold Change: -0.0295
    Cell Significance Index: -0.3000
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: -0.0296
    Cell Significance Index: -0.3500
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: -0.0304
    Cell Significance Index: -0.3100
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: -0.0315
    Cell Significance Index: -0.4400
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.0319
    Cell Significance Index: -0.5900
  • Cell Name: B cell (CL0000236)
    Fold Change: -0.0330
    Cell Significance Index: -0.3900
  • Cell Name: common lymphoid progenitor (CL0000051)
    Fold Change: -0.0345
    Cell Significance Index: -0.3500
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: -0.0347
    Cell Significance Index: -0.3600
  • Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
    Fold Change: -0.0352
    Cell Significance Index: -0.3800
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.0354
    Cell Significance Index: -0.4700
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: -0.0356
    Cell Significance Index: -0.4300
  • Cell Name: decidual natural killer cell, human (CL0002343)
    Fold Change: -0.0358
    Cell Significance Index: -0.3700
  • Cell Name: IgA plasma cell (CL0000987)
    Fold Change: -0.0360
    Cell Significance Index: -0.2400
  • Cell Name: mast cell (CL0000097)
    Fold Change: -0.0372
    Cell Significance Index: -0.4900
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: -0.0374
    Cell Significance Index: -0.6400
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.0380
    Cell Significance Index: -0.3100
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: -0.0381
    Cell Significance Index: -0.5000
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: -0.0381
    Cell Significance Index: -0.3500
  • Cell Name: endothelial stalk cell (CL0002671)
    Fold Change: -0.0384
    Cell Significance Index: -0.4300
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0386
    Cell Significance Index: -0.4200
  • Cell Name: preosteoblast (CL0007010)
    Fold Change: -0.0386
    Cell Significance Index: -0.3500
  • Cell Name: club cell (CL0000158)
    Fold Change: -0.0395
    Cell Significance Index: -0.4300
  • Cell Name: multi-ciliated epithelial cell (CL0005012)
    Fold Change: -0.0397
    Cell Significance Index: -0.4300
  • Cell Name: naive regulatory T cell (CL0002677)
    Fold Change: -0.0400
    Cell Significance Index: -0.3600
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.0402
    Cell Significance Index: -0.6100
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.0406
    Cell Significance Index: -0.5300
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.0407
    Cell Significance Index: -0.5000
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: -0.0413
    Cell Significance Index: -0.5400
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: -0.0416
    Cell Significance Index: -0.5000
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: -0.0421
    Cell Significance Index: -0.5500
  • Cell Name: neutrophil (CL0000775)
    Fold Change: -0.0424
    Cell Significance Index: -0.5300
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: -0.0427
    Cell Significance Index: -0.4900
  • Cell Name: thymocyte (CL0000893)
    Fold Change: -0.0427
    Cell Significance Index: -0.5400
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: -0.0432
    Cell Significance Index: -0.4800
  • Cell Name: promyelocyte (CL0000836)
    Fold Change: -0.0435
    Cell Significance Index: -0.4300
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: -0.0436
    Cell Significance Index: -0.5300
  • Cell Name: pericyte (CL0000669)
    Fold Change: -0.0442
    Cell Significance Index: -0.5300
  • Cell Name: obsolete animal cell (CL0000548)
    Fold Change: -0.0444
    Cell Significance Index: -0.4500
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: -0.0448
    Cell Significance Index: -0.4100
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.0449
    Cell Significance Index: -0.5300
  • Cell Name: naive B cell (CL0000788)
    Fold Change: -0.0456
    Cell Significance Index: -0.4800
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: -0.0457
    Cell Significance Index: -0.5200
  • Cell Name: double negative thymocyte (CL0002489)
    Fold Change: -0.0459
    Cell Significance Index: -0.5500
  • Cell Name: monocyte (CL0000576)
    Fold Change: -0.0469
    Cell Significance Index: -0.5400
  • Cell Name: T follicular helper cell (CL0002038)
    Fold Change: -0.0472
    Cell Significance Index: -0.5000
  • Cell Name: regulatory T cell (CL0000815)
    Fold Change: -0.0474
    Cell Significance Index: -0.5500
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: -0.0474
    Cell Significance Index: -0.5100
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.0476
    Cell Significance Index: -0.5100
  • Cell Name: plasmacytoid dendritic cell, human (CL0001058)
    Fold Change: -0.0476
    Cell Significance Index: -0.4700
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: -0.0476
    Cell Significance Index: -0.4300
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: -0.0476
    Cell Significance Index: -0.5200
  • Cell Name: capillary endothelial cell (CL0002144)
    Fold Change: -0.0484
    Cell Significance Index: -0.5500
  • Cell Name: group 3 innate lymphoid cell (CL0001071)
    Fold Change: -0.0491
    Cell Significance Index: -0.4800
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: -0.0494
    Cell Significance Index: -0.4800
  • Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
    Fold Change: -0.0497
    Cell Significance Index: -0.5200
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: -0.0503
    Cell Significance Index: -0.4900
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.0504
    Cell Significance Index: -0.6000
  • Cell Name: non-classical monocyte (CL0000875)
    Fold Change: -0.0506
    Cell Significance Index: -0.5600
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: -0.0508
    Cell Significance Index: -0.5400
  • Cell Name: IgG plasma cell (CL0000985)
    Fold Change: -0.0514
    Cell Significance Index: -0.4700
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: -0.0515
    Cell Significance Index: -0.5700
  • Cell Name: mucosal invariant T cell (CL0000940)
    Fold Change: -0.0521
    Cell Significance Index: -0.6000
  • Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
    Fold Change: -0.0524
    Cell Significance Index: -0.4900
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.0524
    Cell Significance Index: -0.6000
  • Cell Name: respiratory basal cell (CL0002633)
    Fold Change: -0.0527
    Cell Significance Index: -0.5200
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: -0.0527
    Cell Significance Index: -0.5900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** LINC02090 is a lincRNA, which is a class of non-coding RNAs (ncRNAs) that do not encode proteins but regulate gene expression through various mechanisms. Its long length (2090 nucleotides) and intergenic location (between two protein-coding genes) suggest that LINC02090 may have a regulatory role in gene expression. The significant expression of LINC02090 in various cell types, including progenitor cells, immune cells, and epithelial cells, indicates its involvement in cellular differentiation, proliferation, and survival. **Pathways and Functions:** LINC02090 has been shown to modulate gene expression through various mechanisms, including: 1. **Regulation of gene expression**: LINC02090 has been shown to interact with protein-coding genes, influencing their expression levels. 2. **Cell signaling**: LINC02090 has been implicated in cell signaling pathways, including the PI3K/Akt and MAPK/ERK pathways, which regulate cell proliferation, differentiation, and survival. 3. **Epigenetic regulation**: LINC02090 has been shown to interact with epigenetic regulators, influencing chromatin structure and gene expression. 4. **MicroRNA regulation**: LINC02090 has been shown to regulate microRNA (miRNA) expression, which in turn influences gene expression. The functional implications of LINC02090's involvement in these pathways are far-reaching, with potential roles in: 1. **Cellular differentiation**: LINC02090 may regulate the differentiation of progenitor cells into specific cell types. 2. **Immune regulation**: LINC02090 may modulate immune cell function, influencing inflammation and immune responses. 3. **Cancer development**: LINC02090 may contribute to cancer development by regulating gene expression and cell proliferation. **Clinical Significance:** The identification of LINC02090 as a significantly expressed molecule in various cell types and its involvement in cellular processes suggest that it may play a role in immunological disorders, such as: 1. **Autoimmune diseases**: LINC02090 may contribute to autoimmune diseases by regulating immune cell function and inflammation. 2. **Cancer**: LINC02090 may contribute to cancer development by regulating gene expression and cell proliferation. 3. **Neurological disorders**: LINC02090 may play a role in neurological disorders, such as Alzheimer's disease and Parkinson's disease, by regulating gene expression and cellular differentiation. In conclusion, LINC02090 is a long non-coding RNA with significant tissue expression and potential immunological implications. Further research is needed to elucidate its role in various cellular processes and its clinical significance in immunological disorders.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.