Details for: EIF3FP2

Gene ID: 83880

Symbol: EIF3FP2

Ensembl ID: ENSG00000279081

Description: eukaryotic translation initiation factor 3 subunit F pseudogene 2

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: 0.6281
    Cell Significance Index: 7.1100
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.3125
    Cell Significance Index: 5.2300
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: 0.2668
    Cell Significance Index: 1.6700
  • Cell Name: thymocyte (CL0000893)
    Fold Change: 0.2635
    Cell Significance Index: 3.3300
  • Cell Name: promonocyte (CL0000559)
    Fold Change: 0.2378
    Cell Significance Index: 2.5400
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 0.2231
    Cell Significance Index: 3.5800
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 0.2004
    Cell Significance Index: 1.6000
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 0.1506
    Cell Significance Index: 1.7800
  • Cell Name: decidual natural killer cell, human (CL0002343)
    Fold Change: 0.1199
    Cell Significance Index: 1.2400
  • Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
    Fold Change: 0.1011
    Cell Significance Index: 1.0900
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.0955
    Cell Significance Index: 1.3600
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 0.0921
    Cell Significance Index: 2.3000
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 0.0786
    Cell Significance Index: 2.3200
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 0.0568
    Cell Significance Index: 1.1100
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: 0.0348
    Cell Significance Index: 0.4500
  • Cell Name: microglial cell (CL0000129)
    Fold Change: 0.0272
    Cell Significance Index: 0.3200
  • Cell Name: early lymphoid progenitor (CL0000936)
    Fold Change: 0.0094
    Cell Significance Index: 0.1000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.0069
    Cell Significance Index: 0.7000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0016
    Cell Significance Index: 0.2800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0013
    Cell Significance Index: -0.7000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0013
    Cell Significance Index: -1.0200
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0013
    Cell Significance Index: -0.0500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0017
    Cell Significance Index: -0.2000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0019
    Cell Significance Index: -0.1000
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.0022
    Cell Significance Index: -0.0300
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0047
    Cell Significance Index: -0.0700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0095
    Cell Significance Index: -1.3000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0109
    Cell Significance Index: -0.2900
  • Cell Name: double negative thymocyte (CL0002489)
    Fold Change: -0.0118
    Cell Significance Index: -0.1400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0154
    Cell Significance Index: -0.7200
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0180
    Cell Significance Index: -0.4600
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.0214
    Cell Significance Index: -0.7900
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: -0.0217
    Cell Significance Index: -0.2100
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.0232
    Cell Significance Index: -0.4000
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.0253
    Cell Significance Index: -0.8800
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.0278
    Cell Significance Index: -0.4000
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: -0.0280
    Cell Significance Index: -0.3300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0302
    Cell Significance Index: -1.5900
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: -0.0357
    Cell Significance Index: -0.4900
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: -0.0365
    Cell Significance Index: -0.4700
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.0395
    Cell Significance Index: -0.4900
  • Cell Name: promyelocyte (CL0000836)
    Fold Change: -0.0415
    Cell Significance Index: -0.4100
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.0433
    Cell Significance Index: -0.8600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0434
    Cell Significance Index: -1.2100
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0479
    Cell Significance Index: -1.2200
  • Cell Name: adipocyte (CL0000136)
    Fold Change: -0.0488
    Cell Significance Index: -0.6500
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.0540
    Cell Significance Index: -0.4400
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: -0.0577
    Cell Significance Index: -0.9400
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0611
    Cell Significance Index: -0.8700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0617
    Cell Significance Index: -1.6800
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: -0.0620
    Cell Significance Index: -0.3900
  • Cell Name: kidney interstitial cell (CL1000500)
    Fold Change: -0.0628
    Cell Significance Index: -0.4700
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0643
    Cell Significance Index: -1.6900
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: -0.0649
    Cell Significance Index: -0.7100
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: -0.0674
    Cell Significance Index: -0.6400
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: -0.0678
    Cell Significance Index: -0.6700
  • Cell Name: myelocyte (CL0002193)
    Fold Change: -0.0721
    Cell Significance Index: -0.7700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0724
    Cell Significance Index: -1.8600
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.0775
    Cell Significance Index: -1.1800
  • Cell Name: amacrine cell (CL0000561)
    Fold Change: -0.0783
    Cell Significance Index: -0.9800
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.0787
    Cell Significance Index: -0.6500
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: -0.0804
    Cell Significance Index: -1.0400
  • Cell Name: retina horizontal cell (CL0000745)
    Fold Change: -0.0805
    Cell Significance Index: -1.0100
  • Cell Name: CD8-positive, alpha-beta thymocyte (CL0000811)
    Fold Change: -0.0810
    Cell Significance Index: -0.7500
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: -0.0812
    Cell Significance Index: -0.9800
  • Cell Name: myoepithelial cell (CL0000185)
    Fold Change: -0.0816
    Cell Significance Index: -0.9300
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: -0.0818
    Cell Significance Index: -0.8800
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.0824
    Cell Significance Index: -0.9800
  • Cell Name: lung macrophage (CL1001603)
    Fold Change: -0.0888
    Cell Significance Index: -0.9700
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: -0.0890
    Cell Significance Index: -0.6800
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: -0.0904
    Cell Significance Index: -1.2500
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: -0.0921
    Cell Significance Index: -1.0400
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.0928
    Cell Significance Index: -1.3900
  • Cell Name: basophil mast progenitor cell (CL0002028)
    Fold Change: -0.0948
    Cell Significance Index: -0.8000
  • Cell Name: CD16-positive, CD56-dim natural killer cell, human (CL0000939)
    Fold Change: -0.0972
    Cell Significance Index: -0.8700
  • Cell Name: granulocyte (CL0000094)
    Fold Change: -0.0987
    Cell Significance Index: -1.1900
  • Cell Name: stromal cell (CL0000499)
    Fold Change: -0.0989
    Cell Significance Index: -1.0100
  • Cell Name: pulmonary alveolar type 2 cell (CL0002063)
    Fold Change: -0.0991
    Cell Significance Index: -0.8200
  • Cell Name: neutrophil (CL0000775)
    Fold Change: -0.0993
    Cell Significance Index: -1.2400
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.0995
    Cell Significance Index: -1.6900
  • Cell Name: fibroblast (CL0000057)
    Fold Change: -0.1001
    Cell Significance Index: -0.9400
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: -0.1011
    Cell Significance Index: -1.1300
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: -0.1017
    Cell Significance Index: -1.2400
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: -0.1019
    Cell Significance Index: -1.4000
  • Cell Name: osteoclast (CL0000092)
    Fold Change: -0.1029
    Cell Significance Index: -1.0500
  • Cell Name: mammary gland epithelial cell (CL0002327)
    Fold Change: -0.1043
    Cell Significance Index: -0.4800
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.1046
    Cell Significance Index: -1.3900
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: -0.1054
    Cell Significance Index: -1.5300
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: -0.1070
    Cell Significance Index: -0.9000
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.1076
    Cell Significance Index: -1.2800
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.1076
    Cell Significance Index: -2.6800
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: -0.1090
    Cell Significance Index: -1.4300
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.1100
    Cell Significance Index: -1.1600
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.1108
    Cell Significance Index: -1.0500
  • Cell Name: mast cell (CL0000097)
    Fold Change: -0.1109
    Cell Significance Index: -1.4600
  • Cell Name: vascular associated smooth muscle cell (CL0000359)
    Fold Change: -0.1111
    Cell Significance Index: -1.1800
  • Cell Name: follicular B cell (CL0000843)
    Fold Change: -0.1119
    Cell Significance Index: -0.5600
  • Cell Name: progenitor cell (CL0011026)
    Fold Change: -0.1120
    Cell Significance Index: -1.1900
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: -0.1129
    Cell Significance Index: -1.4100
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.1132
    Cell Significance Index: -1.5700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Pseudogene status:** EIF3FP2 is a pseudogene, meaning it lacks a functional protein-coding sequence. Despite this, it is significantly expressed in various tissues, suggesting alternative regulatory mechanisms or novel functions. 2. **Widespread expression:** EIF3FP2 is expressed in multiple cell types, including goblet cells, intestinal crypt stem cells, absorptive cells, transit amplifying cells, and others. This widespread expression suggests a potential role in tissue homeostasis and development. 3. **Tissue specificity:** EIF3FP2's expression patterns are tissue-specific, with significant expression in the gastrointestinal tract and kidney. This tissue specificity may be related to its role in maintaining tissue homeostasis or responding to environmental cues. **Pathways and Functions:** 1. **Translation initiation:** EIF3FP2's expression in eukaryotic translation initiation factors (eIFs) suggests a potential role in regulating translation initiation. However, its pseudogene status complicates the interpretation of its function. 2. **Cell signaling:** EIF3FP2's expression in various cell types, including those involved in immune responses, suggests a potential role in cell signaling pathways. Its pseudogene status may allow it to modulate these pathways without generating a functional protein. 3. **Tissue development and homeostasis:** EIF3FP2's expression in stem cells and other cell types involved in tissue development and homeostasis suggests a potential role in maintaining tissue balance and responding to environmental cues. **Clinical Significance:** 1. **Cancer associations:** EIF3FP2's expression in neoplastic cells and its potential role in cell signaling pathways make it a potential biomarker for cancer diagnosis and treatment. 2. **Immunology:** EIF3FP2's expression in immune cells and its potential role in cell signaling pathways suggest a potential role in immunomodulation and disease. 3. **Gastrointestinal disorders:** EIF3FP2's expression in the gastrointestinal tract and its potential role in tissue homeostasis make it a potential target for the treatment of gastrointestinal disorders, such as inflammatory bowel disease. In conclusion, EIF3FP2's enigmatic expression patterns and potential functions warrant further investigation. Its pseudogene status and widespread expression in various tissues suggest a complex role in regulating translation initiation, cell signaling, and tissue development and homeostasis. Its clinical significance, particularly in cancer and immunology, highlights the need for further research into the functional implications of EIF3FP2.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.