NMI | ENSG00000123609 | NCBI 9111

Details for: NMI

Gene ID: 9111

Symbol: NMI

Ensembl ID: ENSG00000123609

Description: N-myc and STAT interactor

Associated with

Disease
(R-HSA-1643685)
Infectious disease
(R-HSA-5663205)
Sars-cov-1 activates/modulates innate immune responses
(R-HSA-9692916)
Sars-cov-1 infection
(R-HSA-9678108)
Sars-cov-1-host interactions
(R-HSA-9692914)
Sars-cov infections
(R-HSA-9679506)
Viral infection pathways
(R-HSA-9824446)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Extracellular space
(GO:0005615)
Identical protein binding
(GO:0042802)
Innate immune response
(GO:0045087)
Macrophage activation involved in immune response
(GO:0002281)
Membrane
(GO:0016020)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of innate immune response
(GO:0045824)
Negative regulation of interferon-alpha production
(GO:0032687)
Negative regulation of interferon-beta production
(GO:0032688)
Negative regulation of non-canonical nf-kappab signal transduction
(GO:1901223)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of inflammatory response
(GO:0050729)
Positive regulation of innate immune response
(GO:0045089)
Positive regulation of non-canonical nf-kappab signal transduction
(GO:1901224)
Positive regulation of protein k48-linked ubiquitination
(GO:1902524)
Protein binding
(GO:0005515)
Protein k48-linked ubiquitination
(GO:0070936)
Receptor signaling pathway via jak-stat
(GO:0007259)
Response to virus
(GO:0009615)
Toll-like receptor 4 signaling pathway
(GO:0034142)

Other Information

Proteins

NMI_HUMAN

Genular Protein ID: 2533727068

Symbol: NMI_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q13287 B5BU69 Q53TI8 Q8WTW2 Q9BVE5

Database IDs:

Citations:

PubMed ID: 8668343

Title: Isolation and characterization of Nmi, a novel partner of Myc proteins.

PubMed ID: 8668343

PubMed ID: 19054851

Title: Human protein factory for converting the transcriptome into an in vitro-expressed proteome.

PubMed ID: 19054851

DOI: 10.1038/nmeth.1273

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9781816

Title: Interferon-induced upregulation and cytoplasmic localization of Myc-interacting protein Nmi.

PubMed ID: 9781816

DOI: 10.1089/jir.1998.18.767

PubMed ID: 9989503

Title: Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNgamma-mediated signaling.

PubMed ID: 9989503

DOI: 10.1016/s0092-8674(00)80965-4

PubMed ID: 10779520

Title: Interferon-alpha induces nmi-IFP35 heterodimeric complex formation that is affected by the phosphorylation of IFP35.

PubMed ID: 10779520

DOI: 10.1074/jbc.m003177200

PubMed ID: 10950963

Title: Interferon-inducible Myc/STAT-interacting protein Nmi associates with IFP 35 into a high molecular mass complex and inhibits proteasome-mediated degradation of IFP 35.

PubMed ID: 10950963

DOI: 10.1074/jbc.m006975200

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 26342464

Title: Trim21 regulates Nmi-IFI35 complex-mediated inhibition of innate antiviral response.

PubMed ID: 26342464

DOI: 10.1016/j.virol.2015.08.013

PubMed ID: 29038465

Title: NMI and IFP35 serve as proinflammatory DAMPs during cellular infection and injury.

PubMed ID: 29038465

DOI: 10.1038/s41467-017-00930-9

PubMed ID: 29350881

Title: Interferon-induced protein 35 inhibits endothelial cell proliferation, migration and re-endothelialization of injured arteries by inhibiting the nuclear factor-kappa B pathway.

PubMed ID: 29350881

DOI: 10.1111/apha.13037

PubMed ID: 29377960

Title: Human cytomegalovirus UL23 inhibits transcription of interferon-gamma stimulated genes and blocks antiviral interferon-gamma responses by interacting with human N-myc interactor protein.

PubMed ID: 29377960

DOI: 10.1371/journal.ppat.1006867

Sequence Information:

Length: 307
Mass: 35057
Checksum: EC228BD0C9E643F1
Sequence:

MEADKDDTQQ ILKEHSPDEF IKDEQNKGLI DEITKKNIQL KKEIQKLETE LQEATKEFQI 
KEDIPETKMK FLSVETPEND SQLSNISCSF QVSSKVPYEI QKGQALITFE KEEVAQNVVS 
MSKHHVQIKD VNLEVTAKPV PLNSGVRFQV YVEVSKMKIN VTEIPDTLRE DQMRDKLELS 
FSKSRNGGGE VDRVDYDRQS GSAVITFVEI GVADKILKKK EYPLYINQTC HRVTVSPYTE 
IHLKKYQIFS GTSKRTVLLT GMEGIQMDEE IVEDLINIHF QRAKNGGGEV DVVKCSLGQP 
HIAYFEE

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: NMI

Associated with

Other Information

Isolation and characterization of Nmi, a novel partner of Myc proteins. PubMed ID: 8668343

Human protein factory for converting the transcriptome into an in vitro-expressed proteome. PubMed ID: 19054851

Generation and annotation of the DNA sequences of human chromosomes 2 and 4. PubMed ID: 15815621

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Interferon-induced upregulation and cytoplasmic localization of Myc-interacting protein Nmi. PubMed ID: 9781816

Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNgamma-mediated signaling. PubMed ID: 9989503

Interferon-alpha induces nmi-IFP35 heterodimeric complex formation that is affected by the phosphorylation of IFP35. PubMed ID: 10779520

Interferon-inducible Myc/STAT-interacting protein Nmi associates with IFP 35 into a high molecular mass complex and inhibits proteasome-mediated degradation of IFP 35. PubMed ID: 10950963

Initial characterization of the human central proteome. PubMed ID: 21269460

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

Trim21 regulates Nmi-IFI35 complex-mediated inhibition of innate antiviral response. PubMed ID: 26342464

NMI and IFP35 serve as proinflammatory DAMPs during cellular infection and injury. PubMed ID: 29038465

Interferon-induced protein 35 inhibits endothelial cell proliferation, migration and re-endothelialization of injured arteries by inhibiting the nuclear factor-kappa B pathway. PubMed ID: 29350881

Human cytomegalovirus UL23 inhibits transcription of interferon-gamma stimulated genes and blocks antiviral interferon-gamma responses by interacting with human N-myc interactor protein. PubMed ID: 29377960