Details for: TREX1

Gene ID: 11277

Symbol: TREX1

Ensembl ID: ENSG00000213689

Description: three prime repair exonuclease 1

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: T-helper 17 cell (CL0000899)
    Fold Change: 11.08
    Marker Score: 7,269
  • Cell Name: OFF-bipolar cell (CL0000750)
    Fold Change: 4.68
    Marker Score: 13,881
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 3.26
    Marker Score: 1,497
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: 2.69
    Marker Score: 22,753
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 2.63
    Marker Score: 7,876
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: 2.25
    Marker Score: 6,568
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 1.85
    Marker Score: 3,505
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: 1.23
    Marker Score: 3,526
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 1.11
    Marker Score: 7,127
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 1.02
    Marker Score: 776
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,793
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 48,019
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 0.99
    Marker Score: 2,463
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 0.95
    Marker Score: 298
  • Cell Name: lung secretory cell (CL1000272)
    Fold Change: 0.95
    Marker Score: 847
  • Cell Name: renal beta-intercalated cell (CL0002201)
    Fold Change: 0.95
    Marker Score: 300
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 0.89
    Marker Score: 1,802
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 0.84
    Marker Score: 443
  • Cell Name: lung ciliated cell (CL1000271)
    Fold Change: 0.82
    Marker Score: 391
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: 0.8
    Marker Score: 328
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.79
    Marker Score: 254
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 0.78
    Marker Score: 942
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 0.77
    Marker Score: 776
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.74
    Marker Score: 383
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 0.7
    Marker Score: 543
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.67
    Marker Score: 171
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 0.64
    Marker Score: 234
  • Cell Name: tracheal goblet cell (CL1000329)
    Fold Change: 0.62
    Marker Score: 1,747
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.58
    Marker Score: 3,479
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.55
    Marker Score: 8,673
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 0.55
    Marker Score: 1,284
  • Cell Name: central memory CD4-positive, alpha-beta T cell (CL0000904)
    Fold Change: 0.54
    Marker Score: 584
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.54
    Marker Score: 257
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: 0.53
    Marker Score: 246
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: 0.5
    Marker Score: 110
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 0.48
    Marker Score: 441
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 0.48
    Marker Score: 124
  • Cell Name: type I pneumocyte (CL0002062)
    Fold Change: 0.46
    Marker Score: 559
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 0.45
    Marker Score: 268
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: 0.45
    Marker Score: 377
  • Cell Name: enterocyte (CL0000584)
    Fold Change: 0.45
    Marker Score: 2,137
  • Cell Name: neuronal receptor cell (CL0000006)
    Fold Change: 0.44
    Marker Score: 195
  • Cell Name: podocyte (CL0000653)
    Fold Change: 0.43
    Marker Score: 160
  • Cell Name: erythroblast (CL0000765)
    Fold Change: 0.43
    Marker Score: 266
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 0.41
    Marker Score: 411
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 0.41
    Marker Score: 287
  • Cell Name: alternatively activated macrophage (CL0000890)
    Fold Change: 0.41
    Marker Score: 169
  • Cell Name: exhausted T cell (CL0011025)
    Fold Change: 0.4
    Marker Score: 229
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 0.39
    Marker Score: 269
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.39
    Marker Score: 103
  • Cell Name: non-classical monocyte (CL0000875)
    Fold Change: 0.39
    Marker Score: 935
  • Cell Name: myeloid dendritic cell (CL0000782)
    Fold Change: 0.38
    Marker Score: 231
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.36
    Marker Score: 219
  • Cell Name: CD16-positive, CD56-dim natural killer cell, human (CL0000939)
    Fold Change: 0.36
    Marker Score: 278
  • Cell Name: mucus secreting cell (CL0000319)
    Fold Change: 0.36
    Marker Score: 91
  • Cell Name: activated CD4-positive, alpha-beta T cell, human (CL0001043)
    Fold Change: 0.35
    Marker Score: 161
  • Cell Name: professional antigen presenting cell (CL0000145)
    Fold Change: 0.35
    Marker Score: 182
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: 0.35
    Marker Score: 345
  • Cell Name: microglial cell (CL0000129)
    Fold Change: 0.34
    Marker Score: 624
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 0.33
    Marker Score: 480
  • Cell Name: neutrophil (CL0000775)
    Fold Change: 0.33
    Marker Score: 201
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 0.32
    Marker Score: 281
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 0.32
    Marker Score: 204
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.32
    Marker Score: 2,813
  • Cell Name: CD8-positive, alpha-beta cytotoxic T cell (CL0000794)
    Fold Change: 0.31
    Marker Score: 277
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.3
    Marker Score: 844
  • Cell Name: double negative thymocyte (CL0002489)
    Fold Change: 0.29
    Marker Score: 407
  • Cell Name: ciliated epithelial cell (CL0000067)
    Fold Change: 0.29
    Marker Score: 133
  • Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell (CL0000895)
    Fold Change: 0.28
    Marker Score: 483
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: 0.28
    Marker Score: 151
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 0.28
    Marker Score: 80
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: 0.27
    Marker Score: 1,142
  • Cell Name: T follicular helper cell (CL0002038)
    Fold Change: 0.27
    Marker Score: 222
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 0.26
    Marker Score: 236
  • Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
    Fold Change: 0.26
    Marker Score: 508
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: 0.26
    Marker Score: 169
  • Cell Name: mesenchymal lymphangioblast (CL0005021)
    Fold Change: 0.26
    Marker Score: 57
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 0.25
    Marker Score: 105
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 0.25
    Marker Score: 266
  • Cell Name: B cell (CL0000236)
    Fold Change: 0.25
    Marker Score: 238
  • Cell Name: IgG plasma cell (CL0000985)
    Fold Change: 0.25
    Marker Score: 109
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.25
    Marker Score: 164
  • Cell Name: paneth cell (CL0000510)
    Fold Change: 0.25
    Marker Score: 172
  • Cell Name: precursor cell (CL0011115)
    Fold Change: 0.24
    Marker Score: 59
  • Cell Name: intraepithelial lymphocyte (CL0002496)
    Fold Change: 0.24
    Marker Score: 270
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: 0.24
    Marker Score: 86
  • Cell Name: plasmablast (CL0000980)
    Fold Change: 0.23
    Marker Score: 312
  • Cell Name: type A enteroendocrine cell (CL0002067)
    Fold Change: 0.23
    Marker Score: 93
  • Cell Name: erythroid lineage cell (CL0000764)
    Fold Change: 0.22
    Marker Score: 109
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: 0.22
    Marker Score: 185
  • Cell Name: ILC1, human (CL0001077)
    Fold Change: 0.22
    Marker Score: 55
  • Cell Name: conventional dendritic cell (CL0000990)
    Fold Change: 0.22
    Marker Score: 149
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: 0.21
    Marker Score: 231
  • Cell Name: memory T cell (CL0000813)
    Fold Change: 0.21
    Marker Score: 91
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: 0.21
    Marker Score: 273
  • Cell Name: endothelial cell of artery (CL1000413)
    Fold Change: 0.21
    Marker Score: 87
  • Cell Name: B-1a B cell (CL0000820)
    Fold Change: 0.2
    Marker Score: 49
  • Cell Name: dendritic cell, human (CL0001056)
    Fold Change: 0.2
    Marker Score: 208
  • Cell Name: leukocyte (CL0000738)
    Fold Change: 0.2
    Marker Score: 117
  • Cell Name: secretory cell (CL0000151)
    Fold Change: 0.2
    Marker Score: 370

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** TREX1 is a 3'-5' exonuclease enzyme that is highly specific for single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA) substrates. Its primary function is to remove damaged or mismatched DNA bases, thereby preventing mutations and maintaining genetic integrity. TREX1 is also involved in the regulation of various cellular processes, including: * Immune response: TREX1 is highly expressed in immune cells, particularly T-helper 17 cells, and is involved in the activation of innate immunity and the production of type I interferons. * DNA repair: TREX1 is a key player in the repair of damaged DNA, including the removal of mismatched bases and the correction of DNA lesions. * Metabolism: TREX1 is involved in the regulation of cellular respiration and metabolism, including the regulation of glycolytic and fatty acid metabolic processes. * Development: TREX1 is implicated in the development of the heart and blood vessels, as well as the regulation of cellular differentiation and proliferation. **Pathways and Functions** TREX1 is involved in several cellular pathways, including: * Activation of immune response: TREX1 is highly expressed in immune cells and is involved in the activation of innate immunity and the production of type I interferons. * Apoptotic cell clearance: TREX1 is involved in the removal of apoptotic cells, which helps to prevent the spread of disease. * DNA repair: TREX1 is a key player in the repair of damaged DNA, including the removal of mismatched bases and the correction of DNA lesions. * Metabolism: TREX1 is involved in the regulation of cellular respiration and metabolism, including the regulation of glycolytic and fatty acid metabolic processes. * Development: TREX1 is implicated in the development of the heart and blood vessels, as well as the regulation of cellular differentiation and proliferation. **Clinical Significance** Dysregulation of TREX1 has been implicated in several diseases, including: * Atherosclerosis: TREX1 is involved in the regulation of lipid metabolism, and dysregulation of TREX1 has been implicated in the development of atherosclerosis. * Cancer: TREX1 is involved in the regulation of DNA repair, and dysregulation of TREX1 has been implicated in the development of cancer. * Neurodegenerative diseases: TREX1 is involved in the regulation of cellular differentiation and proliferation, and dysregulation of TREX1 has been implicated in the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. * Autoimmune diseases: TREX1 is involved in the regulation of immune responses, and dysregulation of TREX1 has been implicated in the development of autoimmune diseases, such as rheumatoid arthritis and lupus. In conclusion, TREX1 is a critical gene that plays a key role in maintaining genome stability and regulating various cellular processes. Its dysregulation has been implicated in several diseases, highlighting the importance of this gene in human health and disease.

Genular Protein ID: 518114896

Symbol: TREX1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q9NSU2 B2RCN9 Q8TEU2 Q9BPW1 Q9Y4X2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CTD 1 ChEBI 5 DMDM 1 DNASU 1 DisGeNET 1 EC 1 EMBL 10 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 69 Gene3D 1 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 9 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 4 OrthoDB 1 PANTHER 2 PDB 6 PDBsum 4 PIR 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 2 RefSeq 3 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10393201

Title: A human DNA editing enzyme homologous to the Escherichia coli DnaQ/MutD protein.

PubMed ID: 10393201

DOI: 10.1093/emboj/18.13.3868

PubMed ID: 10391904

Title: Identification and expression of the TREX1 and TREX2 cDNA sequences encoding mammalian 3'-->5' exonucleases.

PubMed ID: 10391904

DOI: 10.1074/jbc.274.28.19655

PubMed ID: 11278605

Title: Structure and expression of the TREX1 and TREX2 3'-->5' exonuclease genes.

PubMed ID: 11278605

DOI: 10.1074/jbc.m010051200

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16818237

Title: The exonuclease TREX1 is in the SET complex and acts in concert with NM23-H1 to degrade DNA during granzyme A-mediated cell death.

PubMed ID: 16818237

DOI: 10.1016/j.molcel.2006.06.005

PubMed ID: 18045533

Title: Trex1 exonuclease degrades ssDNA to prevent chronic checkpoint activation and autoimmune disease.

PubMed ID: 18045533

DOI: 10.1016/j.cell.2007.10.017

PubMed ID: 17293595

Title: The crystal structure of TREX1 explains the 3' nucleotide specificity and reveals a polyproline II helix for protein partnering.

PubMed ID: 17293595

DOI: 10.1074/jbc.m700039200

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 23993650

Title: Oxidative damage of DNA confers resistance to cytosolic nuclease TREX1 degradation and potentiates STING-dependent immune sensing.

PubMed ID: 23993650

DOI: 10.1016/j.immuni.2013.08.004

PubMed ID: 23979357

Title: The TREX1 C-terminal region controls cellular localization through ubiquitination.

PubMed ID: 23979357

DOI: 10.1074/jbc.m113.503391

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 33476576

Title: ER-directed TREX1 limits cGAS activation at micronuclei.

PubMed ID: 33476576

DOI: 10.1016/j.molcel.2020.12.037

PubMed ID: 16845398

Title: Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 cause Aicardi-Goutieres syndrome at the AGS1 locus.

PubMed ID: 16845398

DOI: 10.1038/ng1845

PubMed ID: 17357087

Title: Heterozygous mutations in TREX1 cause familial chilblain lupus and dominant Aicardi-Goutieres syndrome.

PubMed ID: 17357087

DOI: 10.1086/513443

PubMed ID: 17846997

Title: Clinical and molecular phenotype of Aicardi-Goutieres syndrome.

PubMed ID: 17846997

DOI: 10.1086/521373

PubMed ID: 17440703

Title: A mutation in TREX1 that impairs susceptibility to granzyme A-mediated cell death underlies familial chilblain lupus.

PubMed ID: 17440703

DOI: 10.1007/s00109-007-0199-9

PubMed ID: 17660818

Title: Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus.

PubMed ID: 17660818

DOI: 10.1038/ng2091

PubMed ID: 17660820

Title: C-terminal truncations in human 3'-5' DNA exonuclease TREX1 cause autosomal dominant retinal vasculopathy with cerebral leukodystrophy.

PubMed ID: 17660820

DOI: 10.1038/ng2082

PubMed ID: 20799324

Title: A de novo p.Asp18Asn mutation in TREX1 in a patient with Aicardi-Goutieres syndrome.

PubMed ID: 20799324

DOI: 10.1002/ajmg.a.33620

PubMed ID: 20131292

Title: Expanding the phenotypic spectrum of lupus erythematosus in Aicardi-Goutieres syndrome.

PubMed ID: 20131292

DOI: 10.1002/art.27367

Sequence Information:

  • Length: 314
  • Mass: 33212
  • Checksum: EE8F63B6496D72F4
  • Sequence:
    • MGSQALPPGP MQTLIFFDME ATGLPFSQPK VTELCLLAVH RCALESPPTS QGPPPTVPPP 
PRVVDKLSLC VAPGKACSPA ASEITGLSTA VLAAHGRQCF DDNLANLLLA FLRRQPQPWC 
LVAHNGDRYD FPLLQAELAM LGLTSALDGA FCVDSITALK ALERASSPSE HGPRKSYSLG 
SIYTRLYGQS PPDSHTAEGD VLALLSICQW RPQALLRWVD AHARPFGTIR PMYGVTASAR 
TKPRPSAVTT TAHLATTRNT SPSLGESRGT KDLPPVKDPG ALSREGLLAP LGLLAILTLA 
VATLYGLSLA TPGE

Genular Protein ID: 3214235001

Symbol: Q5TZT0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q5TZT0

Database IDs:

ARBA 4 AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CTD 1 ChEBI 1 DNASU 1 EC 1 EMBL 5 ExpressionAtlas 1 GO 4 Gene3D 1 GenomeRNAi 1 HOGENOM 1 IntAct 1 InterPro 4 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 RefSeq 1 SAM 2 SMART 2 SMR 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 304
  • Mass: 32276
  • Checksum: 922048DCC4122124
  • Sequence:
    • MQTLIFFDME ATGLPFSQPK VTELCLLAVH RCALESPPTS QGPPPTVPPP PRVVDKLSLC 
VAPGKACSPA ASEITGLSTA VLAAHGRQCF DDNLANLLLA FLRRQPQPWC LVAHNGDRYD 
FPLLQAELAM LGLTSALDGA FCVDSITALK ALERASSPSE HGPRKSYSLG SIYTRLYGQS 
PPDSHTAEGD VLALLSICQW RPQALLRWVD AHARPFGTIR PMYGVTASAR TKPRPSAVTT 
TAHLATTRNT SPSLGESRGT KDLPPVKDPG ALSREGLLAP LGLLAILTLA VATLYGLSLA 
TPGE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.