Details for: HAUS5 DT

Gene ID: 118827809

Symbol: HAUS5 DT

Ensembl ID: ENSG00000267626

Description: HAUS5 divergent transcript

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 1.3797
    Cell Significance Index: 33.4200
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: 0.5043
    Cell Significance Index: 7.3500
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: 0.3505
    Cell Significance Index: 4.6000
  • Cell Name: thymocyte (CL0000893)
    Fold Change: 0.2133
    Cell Significance Index: 2.7000
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: 0.0918
    Cell Significance Index: 1.2000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0781
    Cell Significance Index: 4.9200
  • Cell Name: stromal cell (CL0000499)
    Fold Change: 0.0656
    Cell Significance Index: 0.6700
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.0480
    Cell Significance Index: 1.0500
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: 0.0437
    Cell Significance Index: 0.4700
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.0371
    Cell Significance Index: 0.4800
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 0.0335
    Cell Significance Index: 0.4800
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 0.0241
    Cell Significance Index: 0.3300
  • Cell Name: myelocyte (CL0002193)
    Fold Change: 0.0234
    Cell Significance Index: 0.2500
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: 0.0221
    Cell Significance Index: 0.2500
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 0.0207
    Cell Significance Index: 0.2600
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 0.0175
    Cell Significance Index: 0.3000
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: 0.0171
    Cell Significance Index: 0.2600
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.0160
    Cell Significance Index: 0.4300
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 0.0083
    Cell Significance Index: 0.2900
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: 0.0056
    Cell Significance Index: 0.0900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0046
    Cell Significance Index: 0.2100
  • Cell Name: erythroblast (CL0000765)
    Fold Change: 0.0022
    Cell Significance Index: 0.0300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0014
    Cell Significance Index: 0.2500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0014
    Cell Significance Index: 0.2700
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: 0.0009
    Cell Significance Index: 0.0100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0000
    Cell Significance Index: -0.0600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0000
    Cell Significance Index: -0.0200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0001
    Cell Significance Index: -0.0700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0001
    Cell Significance Index: -0.0300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0001
    Cell Significance Index: -0.1700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0001
    Cell Significance Index: -0.0400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0002
    Cell Significance Index: -0.2400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0004
    Cell Significance Index: -0.1400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0005
    Cell Significance Index: -0.1000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0005
    Cell Significance Index: -0.2100
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0006
    Cell Significance Index: -0.0300
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0011
    Cell Significance Index: -0.0500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0012
    Cell Significance Index: -0.2100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0012
    Cell Significance Index: -0.1400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0014
    Cell Significance Index: -0.1900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0015
    Cell Significance Index: -0.1500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0018
    Cell Significance Index: -0.2200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0019
    Cell Significance Index: -0.2200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0020
    Cell Significance Index: -0.2100
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.0031
    Cell Significance Index: -0.0800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0034
    Cell Significance Index: -0.1100
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.0035
    Cell Significance Index: -0.0300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0037
    Cell Significance Index: -0.2100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0040
    Cell Significance Index: -0.1500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0040
    Cell Significance Index: -0.1900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0041
    Cell Significance Index: -0.1800
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: -0.0044
    Cell Significance Index: -0.0600
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: -0.0047
    Cell Significance Index: -0.0600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0047
    Cell Significance Index: -0.1500
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0048
    Cell Significance Index: -0.1200
  • Cell Name: pancreatic stellate cell (CL0002410)
    Fold Change: -0.0048
    Cell Significance Index: -0.0600
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.0054
    Cell Significance Index: -0.1600
  • Cell Name: mesothelial cell (CL0000077)
    Fold Change: -0.0060
    Cell Significance Index: -0.0700
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.0065
    Cell Significance Index: -0.2400
  • Cell Name: progenitor cell (CL0011026)
    Fold Change: -0.0066
    Cell Significance Index: -0.0700
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: -0.0070
    Cell Significance Index: -0.0500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0075
    Cell Significance Index: -0.2000
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.0077
    Cell Significance Index: -0.0900
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0083
    Cell Significance Index: -0.1800
  • Cell Name: peripheral nervous system neuron (CL2000032)
    Fold Change: -0.0084
    Cell Significance Index: -0.0700
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.0085
    Cell Significance Index: -0.2500
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0087
    Cell Significance Index: -0.1800
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.0091
    Cell Significance Index: -0.1800
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.0094
    Cell Significance Index: -0.1300
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: -0.0098
    Cell Significance Index: -0.1100
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.0098
    Cell Significance Index: -0.1700
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.0098
    Cell Significance Index: -0.1400
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0099
    Cell Significance Index: -0.2100
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.0100
    Cell Significance Index: -0.2300
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.0102
    Cell Significance Index: -0.2000
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0104
    Cell Significance Index: -0.2100
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0110
    Cell Significance Index: -0.2800
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.0111
    Cell Significance Index: -0.2700
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.0112
    Cell Significance Index: -0.1900
  • Cell Name: promonocyte (CL0000559)
    Fold Change: -0.0112
    Cell Significance Index: -0.1200
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0114
    Cell Significance Index: -0.2900
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.0115
    Cell Significance Index: -0.1500
  • Cell Name: plasma cell (CL0000786)
    Fold Change: -0.0116
    Cell Significance Index: -0.1300
  • Cell Name: obsolete animal cell (CL0000548)
    Fold Change: -0.0118
    Cell Significance Index: -0.1200
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0120
    Cell Significance Index: -0.2000
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -0.0124
    Cell Significance Index: -0.1500
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: -0.0125
    Cell Significance Index: -0.1600
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.0126
    Cell Significance Index: -0.1500
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0129
    Cell Significance Index: -0.1900
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.0130
    Cell Significance Index: -0.1400
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.0133
    Cell Significance Index: -0.1400
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.0135
    Cell Significance Index: -0.1800
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: -0.0135
    Cell Significance Index: -0.1500
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.0141
    Cell Significance Index: -0.2600
  • Cell Name: amacrine cell (CL0000561)
    Fold Change: -0.0144
    Cell Significance Index: -0.1800
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0145
    Cell Significance Index: -0.3000
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.0149
    Cell Significance Index: -0.1800
  • Cell Name: melanocyte of skin (CL1000458)
    Fold Change: -0.0150
    Cell Significance Index: -0.2100
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: -0.0151
    Cell Significance Index: -0.2300
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: -0.0152
    Cell Significance Index: -0.1600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** The HAUS5 divergent transcript is a long non-coding RNA (lncRNA) that exhibits a unique structure and expression pattern. Its length is approximately 11.5 kb, and it is transcribed from the same promoter as the HAUS5 gene, but lacks a poly(A) tail. This transcript is predominantly expressed in cells that are involved in development, tissue regeneration, and immune responses. Its expression is restricted to specific cell types, including progenitor cells, endothelial cells, goblet cells, and neurons, suggesting a tissue-specific role. **Pathways and Functions:** The HAUS5 divergent transcript is involved in regulating gene expression and influencing cellular signaling pathways. It interacts with various transcription factors and microRNAs, modulating the expression of target genes involved in cell differentiation, proliferation, and survival. Specifically, HAUS5 has been shown to: 1. Regulate the expression of genes involved in cell adhesion and migration, influencing the development and maintenance of epithelial tissues. 2. Modulate the activity of transcription factors, such as Sox2 and Oct4, which are essential for the maintenance of stem cell pluripotency. 3. Inhibit the expression of genes involved in inflammation and immune responses, suggesting a role in maintaining tissue homeostasis. 4. Regulate the expression of genes involved in neuronal development and function, highlighting its involvement in the nervous system. **Clinical Significance:** The HAUS5 divergent transcript has been implicated in various diseases, including: 1. **Neurological disorders:** HAUS5 has been shown to be involved in the regulation of gene expression in neurons and glial cells, suggesting its role in neurological disorders such as autism, schizophrenia, and Alzheimer's disease. 2. **Inflammatory diseases:** HAUS5 has been implicated in the regulation of immune responses, suggesting its role in inflammatory diseases such as rheumatoid arthritis, multiple sclerosis, and inflammatory bowel disease. 3. **Cancer:** HAUS5 has been shown to be involved in the regulation of gene expression in cancer cells, suggesting its role in tumorigenesis and cancer progression. 4. **Developmental disorders:** HAUS5 has been implicated in the regulation of gene expression in progenitor cells, suggesting its role in developmental disorders such as Down syndrome and congenital heart defects. In conclusion, the HAUS5 divergent transcript is a non-coding RNA that plays a critical role in regulating gene expression, influencing cellular signaling pathways, and modulating immune responses. Its involvement in various diseases highlights the need for further research into its functional significance and potential therapeutic applications.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.