Details for: TRAJ13

Gene ID: 28742

Symbol: TRAJ13

Ensembl ID: ENSG00000211876

Description: T cell receptor alpha joining 13

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: thymocyte (CL0000893)
    Fold Change: 2.6505
    Cell Significance Index: 33.4900
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 1.3892
    Cell Significance Index: 33.6500
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: 0.3437
    Cell Significance Index: 5.0100
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: 0.3201
    Cell Significance Index: 4.2000
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: 0.1327
    Cell Significance Index: 2.1500
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.0829
    Cell Significance Index: 1.8200
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: 0.0574
    Cell Significance Index: 0.9900
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.0073
    Cell Significance Index: 0.3700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0006
    Cell Significance Index: 0.2200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0034
    Cell Significance Index: -0.6900
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: -0.0041
    Cell Significance Index: -0.0500
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: -0.0074
    Cell Significance Index: -0.1000
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: -0.0115
    Cell Significance Index: -0.1500
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.0118
    Cell Significance Index: -0.2000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0118
    Cell Significance Index: -0.5200
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.0143
    Cell Significance Index: -0.2800
  • Cell Name: alpha-beta T cell (CL0000789)
    Fold Change: -0.0147
    Cell Significance Index: -0.1300
  • Cell Name: mast cell (CL0000097)
    Fold Change: -0.0165
    Cell Significance Index: -0.2200
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.0195
    Cell Significance Index: -0.2300
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0195
    Cell Significance Index: -0.7400
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.0201
    Cell Significance Index: -0.2400
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0214
    Cell Significance Index: -0.7000
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.0262
    Cell Significance Index: -0.3700
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: -0.0275
    Cell Significance Index: -0.3100
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.0292
    Cell Significance Index: -0.6100
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: -0.0341
    Cell Significance Index: -0.3900
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: -0.0343
    Cell Significance Index: -0.4400
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: -0.0386
    Cell Significance Index: -0.5200
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.0401
    Cell Significance Index: -0.7900
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.0406
    Cell Significance Index: -0.8100
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0408
    Cell Significance Index: -1.0400
  • Cell Name: CD8-positive, alpha-beta thymocyte (CL0000811)
    Fold Change: -0.0421
    Cell Significance Index: -0.3900
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: -0.0424
    Cell Significance Index: -0.4700
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0446
    Cell Significance Index: -0.9000
  • Cell Name: adipocyte (CL0000136)
    Fold Change: -0.0555
    Cell Significance Index: -0.7400
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -0.0569
    Cell Significance Index: -0.7300
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.0579
    Cell Significance Index: -0.7700
  • Cell Name: mural cell (CL0008034)
    Fold Change: -0.0600
    Cell Significance Index: -0.7300
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.0601
    Cell Significance Index: -1.1100
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -0.0602
    Cell Significance Index: -0.7300
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.0607
    Cell Significance Index: -0.7000
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.0609
    Cell Significance Index: -0.8000
  • Cell Name: amacrine cell (CL0000561)
    Fold Change: -0.0623
    Cell Significance Index: -0.7800
  • Cell Name: neutrophil (CL0000775)
    Fold Change: -0.0624
    Cell Significance Index: -0.7800
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: -0.0637
    Cell Significance Index: -0.8000
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.0672
    Cell Significance Index: -0.7900
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: -0.0678
    Cell Significance Index: -0.6800
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: -0.0680
    Cell Significance Index: -0.7900
  • Cell Name: gamma-delta T cell (CL0000798)
    Fold Change: -0.0691
    Cell Significance Index: -0.6900
  • Cell Name: monocyte (CL0000576)
    Fold Change: -0.0695
    Cell Significance Index: -0.8000
  • Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
    Fold Change: -0.0696
    Cell Significance Index: -0.7500
  • Cell Name: immature alpha-beta T cell (CL0000790)
    Fold Change: -0.0698
    Cell Significance Index: -0.5200
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0710
    Cell Significance Index: -1.4000
  • Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
    Fold Change: -0.0716
    Cell Significance Index: -0.6700
  • Cell Name: vein endothelial cell (CL0002543)
    Fold Change: -0.0719
    Cell Significance Index: -0.7800
  • Cell Name: retinal pigment epithelial cell (CL0002586)
    Fold Change: -0.0725
    Cell Significance Index: -0.7800
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.0737
    Cell Significance Index: -0.9300
  • Cell Name: regulatory T cell (CL0000815)
    Fold Change: -0.0741
    Cell Significance Index: -0.8600
  • Cell Name: macrophage (CL0000235)
    Fold Change: -0.0754
    Cell Significance Index: -0.7700
  • Cell Name: naive regulatory T cell (CL0002677)
    Fold Change: -0.0767
    Cell Significance Index: -0.6900
  • Cell Name: fibroblast (CL0000057)
    Fold Change: -0.0778
    Cell Significance Index: -0.7300
  • Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
    Fold Change: -0.0781
    Cell Significance Index: -0.7400
  • Cell Name: fibroblast of the aortic adventitia (CL0002547)
    Fold Change: -0.0783
    Cell Significance Index: -0.7900
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: -0.0790
    Cell Significance Index: -0.8500
  • Cell Name: obsolete animal cell (CL0000548)
    Fold Change: -0.0823
    Cell Significance Index: -0.8400
  • Cell Name: T follicular helper cell (CL0002038)
    Fold Change: -0.0839
    Cell Significance Index: -0.8900
  • Cell Name: effector memory CD4-positive, alpha-beta T cell (CL0000905)
    Fold Change: -0.0854
    Cell Significance Index: -0.7900
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.0858
    Cell Significance Index: -1.0600
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: -0.0874
    Cell Significance Index: -0.7700
  • Cell Name: B cell (CL0000236)
    Fold Change: -0.0880
    Cell Significance Index: -1.0400
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: -0.0882
    Cell Significance Index: -0.8600
  • Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
    Fold Change: -0.0883
    Cell Significance Index: -0.8900
  • Cell Name: podocyte (CL0000653)
    Fold Change: -0.0889
    Cell Significance Index: -1.0200
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: -0.0895
    Cell Significance Index: -0.8600
  • Cell Name: mucosal invariant T cell (CL0000940)
    Fold Change: -0.0895
    Cell Significance Index: -1.0300
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.0915
    Cell Significance Index: -0.9700
  • Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
    Fold Change: -0.0942
    Cell Significance Index: -0.8100
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.0945
    Cell Significance Index: -0.7800
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: -0.0961
    Cell Significance Index: -1.0100
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: -0.0970
    Cell Significance Index: -0.9800
  • Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell (CL0000895)
    Fold Change: -0.0985
    Cell Significance Index: -0.8500
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: -0.0995
    Cell Significance Index: -1.0100
  • Cell Name: naive B cell (CL0000788)
    Fold Change: -0.1002
    Cell Significance Index: -1.0600
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: -0.1019
    Cell Significance Index: -1.1000
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: -0.1027
    Cell Significance Index: -0.7900
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.1044
    Cell Significance Index: -0.9900
  • Cell Name: kidney collecting duct intercalated cell (CL1001432)
    Fold Change: -0.1071
    Cell Significance Index: -1.0200
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: -0.1085
    Cell Significance Index: -1.0100
  • Cell Name: naive T cell (CL0000898)
    Fold Change: -0.1112
    Cell Significance Index: -1.0100
  • Cell Name: activated CD4-positive, alpha-beta T cell (CL0000896)
    Fold Change: -0.1119
    Cell Significance Index: -0.7700
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: -0.1140
    Cell Significance Index: -1.0300
  • Cell Name: central memory CD4-positive, alpha-beta T cell (CL0000904)
    Fold Change: -0.1189
    Cell Significance Index: -1.0400
  • Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
    Fold Change: -0.1201
    Cell Significance Index: -1.1100
  • Cell Name: CD16-positive, CD56-dim natural killer cell, human (CL0000939)
    Fold Change: -0.1202
    Cell Significance Index: -1.0700
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: -0.1209
    Cell Significance Index: -1.0200
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.1221
    Cell Significance Index: -1.3300
  • Cell Name: activated CD8-positive, alpha-beta T cell (CL0000906)
    Fold Change: -0.1244
    Cell Significance Index: -1.0400
  • Cell Name: CD8-positive, alpha-beta cytotoxic T cell (CL0000794)
    Fold Change: -0.1260
    Cell Significance Index: -1.0200
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: -0.1353
    Cell Significance Index: -1.1100
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: -0.1367
    Cell Significance Index: -1.0500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Expression Profile:** TRAJ13 is significantly expressed in CD4-positive, alpha-beta thymocytes, T cells, and other immune cells, including CD8-positive, alpha-beta memory T cells, mature NK T cells, and retinal rod cells. 2. **Gene Structure:** The gene structure of TRAJ13 is not explicitly mentioned in the provided information, but it is likely to consist of exons and introns that encode a protein with specific functional domains. 3. **Conservation:** The conservation of TRAJ13 across different species suggests its evolutionary importance and potential functional relevance in various biological processes. **Pathways and Functions:** 1. **T Cell Receptor Signaling:** TRAJ13 is likely involved in the regulation of T cell receptor signaling, which is crucial for the activation, proliferation, and differentiation of T cells. 2. **Immune Cell Development:** The expression of TRAJ13 in alpha-beta thymocytes and other immune cells suggests its role in the development and maturation of these cells. 3. **Cell-Cell Interactions:** TRAJ13 may also be involved in cell-cell interactions, such as the regulation of adhesion molecules and the modulation of immune responses. 4. **Gene Regulation:** TRAJ13 may act as a transcriptional regulator, influencing the expression of other genes involved in immune responses. **Clinical Significance:** 1. **Immunodeficiency Disorders:** Mutations or deletions in the TRAJ13 gene may contribute to immunodeficiency disorders, such as impaired T cell function and reduced immune responses. 2. **Autoimmune Diseases:** Dysregulation of TRAJ13 may lead to autoimmune diseases, characterized by excessive or inappropriate immune responses. 3. **Cancer Immunology:** TRAJ13 may play a role in cancer immunology, as its dysregulation can impact the function and efficacy of immune cells in anti-tumor responses. 4. **Neurological Disorders:** The expression of TRAJ13 in retinal rod cells suggests its potential involvement in neurological disorders, such as retinal degeneration and other eye diseases. In conclusion, TRAJ13 is a gene with significant immunological relevance, and its dysregulation may contribute to various immune-related disorders. Further research is needed to elucidate the functional mechanisms of TRAJ13 and its clinical significance in human diseases.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.