Details for: TSC22D1
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: early promyelocyte (CL0002154)
Fold Change: 4.08
Marker Score: 3,265 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 4.01
Marker Score: 3,823 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 3.88
Marker Score: 4,681 - Cell Name: mesodermal cell (CL0000222)
Fold Change: 3.78
Marker Score: 49,821 - Cell Name: alveolar capillary type 1 endothelial cell (CL4028002)
Fold Change: 3.58
Marker Score: 9,103 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 3.5
Marker Score: 7,685 - Cell Name: glycinergic amacrine cell (CL4030028)
Fold Change: 3.4
Marker Score: 3,211 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 3.4
Marker Score: 15,731 - Cell Name: supporting cell (CL0000630)
Fold Change: 3.37
Marker Score: 6,337 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 3.29
Marker Score: 4,431 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 3.25
Marker Score: 3,939 - Cell Name: endothelial cell of uterus (CL0009095)
Fold Change: 3.25
Marker Score: 6,493 - Cell Name: kidney interstitial cell (CL1000500)
Fold Change: 3.23
Marker Score: 2,294 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 3.22
Marker Score: 109,493 - Cell Name: medullary thymic epithelial cell (CL0002365)
Fold Change: 3.18
Marker Score: 5,223 - Cell Name: colon epithelial cell (CL0011108)
Fold Change: 3.09
Marker Score: 9,705 - Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: 3.09
Marker Score: 12,879 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 3.08
Marker Score: 6,266 - Cell Name: kidney collecting duct principal cell (CL1001431)
Fold Change: 3.06
Marker Score: 7,706 - Cell Name: type II pneumocyte (CL0002063)
Fold Change: 2.98
Marker Score: 19,415 - Cell Name: thyroid follicular cell (CL0002258)
Fold Change: 2.98
Marker Score: 2,330 - Cell Name: taste receptor cell (CL0000209)
Fold Change: 2.97
Marker Score: 2,564 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 2.93
Marker Score: 7,340 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 2.93
Marker Score: 11,298 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: 2.92
Marker Score: 1,701 - Cell Name: pulmonary artery endothelial cell (CL1001568)
Fold Change: 2.87
Marker Score: 2,471 - Cell Name: uterine smooth muscle cell (CL0002601)
Fold Change: 2.87
Marker Score: 3,739 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 2.86
Marker Score: 1,706 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 2.8
Marker Score: 818 - Cell Name: theca cell (CL0000503)
Fold Change: 2.79
Marker Score: 2,001 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 2.78
Marker Score: 4,705 - Cell Name: basal cell of epithelium of trachea (CL1000348)
Fold Change: 2.68
Marker Score: 19,939 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 2.68
Marker Score: 11,209 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 2.64
Marker Score: 2,820 - Cell Name: secretory cell (CL0000151)
Fold Change: 2.63
Marker Score: 4,806 - Cell Name: myofibroblast cell (CL0000186)
Fold Change: 2.63
Marker Score: 3,242 - Cell Name: alveolar capillary type 2 endothelial cell (CL4028003)
Fold Change: 2.62
Marker Score: 3,797 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 2.57
Marker Score: 2,963 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 2.57
Marker Score: 1,503 - Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
Fold Change: 2.57
Marker Score: 2,189 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 2.56
Marker Score: 5,351 - Cell Name: cell in vitro (CL0001034)
Fold Change: 2.56
Marker Score: 88,616 - Cell Name: chondrocyte (CL0000138)
Fold Change: 2.54
Marker Score: 1,145 - Cell Name: stellate neuron (CL0000122)
Fold Change: 2.54
Marker Score: 13,650 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 2.52
Marker Score: 50,199 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: 2.48
Marker Score: 4,390 - Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 2.47
Marker Score: 5,824 - Cell Name: peripheral nervous system neuron (CL2000032)
Fold Change: 2.46
Marker Score: 2,760 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 2.45
Marker Score: 9,083 - Cell Name: prostate gland microvascular endothelial cell (CL2000059)
Fold Change: 2.45
Marker Score: 951 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 2.45
Marker Score: 36,579 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 2.44
Marker Score: 4,697 - Cell Name: smooth muscle cell of large intestine (CL1000279)
Fold Change: 2.44
Marker Score: 922 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 2.43
Marker Score: 92,351 - Cell Name: pericyte (CL0000669)
Fold Change: 2.43
Marker Score: 1,417 - Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
Fold Change: 2.42
Marker Score: 1,182 - Cell Name: smooth muscle cell (CL0000192)
Fold Change: 2.41
Marker Score: 1,587 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 2.38
Marker Score: 18,214 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 2.37
Marker Score: 80,140 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 2.37
Marker Score: 1,561 - Cell Name: lymphocyte (CL0000542)
Fold Change: 2.37
Marker Score: 1,196 - Cell Name: basal cell (CL0000646)
Fold Change: 2.35
Marker Score: 3,028 - Cell Name: lactocyte (CL0002325)
Fold Change: 2.35
Marker Score: 37,659 - Cell Name: fibroblast (CL0000057)
Fold Change: 2.34
Marker Score: 2,257 - Cell Name: kidney cell (CL1000497)
Fold Change: 2.33
Marker Score: 1,556 - Cell Name: mesenchymal stem cell (CL0000134)
Fold Change: 2.33
Marker Score: 3,588 - Cell Name: endothelial cell of vascular tree (CL0002139)
Fold Change: 2.33
Marker Score: 3,384 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 2.32
Marker Score: 1,145 - Cell Name: pneumocyte (CL0000322)
Fold Change: 2.32
Marker Score: 3,721 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 2.31
Marker Score: 85,034 - Cell Name: capillary endothelial cell (CL0002144)
Fold Change: 2.3
Marker Score: 2,477 - Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: 2.3
Marker Score: 14,691 - Cell Name: mammary gland epithelial cell (CL0002327)
Fold Change: 2.28
Marker Score: 811 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 2.27
Marker Score: 9,429 - Cell Name: peritubular capillary endothelial cell (CL1001033)
Fold Change: 2.27
Marker Score: 528 - Cell Name: endothelial cell (CL0000115)
Fold Change: 2.27
Marker Score: 2,034 - Cell Name: renal intercalated cell (CL0005010)
Fold Change: 2.27
Marker Score: 1,209 - Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
Fold Change: 2.26
Marker Score: 942 - Cell Name: club cell (CL0000158)
Fold Change: 2.26
Marker Score: 2,635 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 2.25
Marker Score: 8,858 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 2.25
Marker Score: 5,496 - Cell Name: renal principal cell (CL0005009)
Fold Change: 2.22
Marker Score: 1,714 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 2.22
Marker Score: 5,065 - Cell Name: neural crest cell (CL0011012)
Fold Change: 2.22
Marker Score: 2,370 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 2.21
Marker Score: 47,079 - Cell Name: stromal cell of lamina propria of small intestine (CL0009022)
Fold Change: 2.2
Marker Score: 495 - Cell Name: contractile cell (CL0000183)
Fold Change: 2.2
Marker Score: 1,192 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 2.2
Marker Score: 3,240 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 2.2
Marker Score: 1,526 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: 2.19
Marker Score: 2,316 - Cell Name: respiratory goblet cell (CL0002370)
Fold Change: 2.19
Marker Score: 631 - Cell Name: endocrine cell (CL0000163)
Fold Change: 2.18
Marker Score: 1,127 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 2.17
Marker Score: 2,688 - Cell Name: fibroblast of lung (CL0002553)
Fold Change: 2.17
Marker Score: 5,685 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.17
Marker Score: 8,392 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 2.17
Marker Score: 2,338 - Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
Fold Change: 2.16
Marker Score: 725 - Cell Name: epithelial cell of stratum germinativum of esophagus (CL1000447)
Fold Change: 2.14
Marker Score: 517 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 2.14
Marker Score: 5,126 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 2.14
Marker Score: 47,755
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2864549439
Symbol: T22D1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8651929
Title: Cloning of the human homologue of the TGF beta-stimulated clone 22 gene.
PubMed ID: 8651929
PubMed ID: 9022669
Title: Molecular cloning and characterization of a transcription factor for the C-type natriuretic peptide gene promoter.
PubMed ID: 9022669
PubMed ID: 9026990
Title: The characteristics of different types of mRNA expressed in the human brain.
PubMed ID: 9026990
PubMed ID: 12056414
Title: Characterization of size-fractionated cDNA libraries generated by the in vitro recombination-assisted method.
PubMed ID: 12056414
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 15057823
Title: The DNA sequence and analysis of human chromosome 13.
PubMed ID: 15057823
DOI: 10.1038/nature02379
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10488076
Title: Transforming growth factor-beta-stimulated clone-22 is a member of a family of leucine zipper proteins that can homo- and heterodimerize and has transcriptional repressor activity.
PubMed ID: 10488076
PubMed ID: 12468551
Title: Peroxisome proliferator-activated receptor gamma and transforming growth factor-beta pathways inhibit intestinal epithelial cell growth by regulating levels of TSC-22.
PubMed ID: 12468551
PubMed ID: 15881652
Title: Tsc-22 enhances TGF-beta signaling by associating with Smad4 and induces erythroid cell differentiation.
PubMed ID: 15881652
PubMed ID: 18325344
Title: Interaction between fortilin and transforming growth factor-beta stimulated clone-22 (TSC-22) prevents apoptosis via the destabilization of TSC-22.
PubMed ID: 18325344
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21448135
Title: Antagonistic TSC22D1 variants control BRAF(E600)-induced senescence.
PubMed ID: 21448135
PubMed ID: 21791611
Title: TSC-22 promotes transforming growth factor beta-mediated cardiac myofibroblast differentiation by antagonizing Smad7 activity.
PubMed ID: 21791611
DOI: 10.1128/mcb.05448-11
PubMed ID: 26752201
Title: TSC-22 Promotes Interleukin-2-Deprivation Induced Apoptosis in T-Lymphocytes.
PubMed ID: 26752201
DOI: 10.1002/jcb.25485
PubMed ID: 34681573
Title: Identification of Binding Proteins for TSC22D1 Family Proteins Using Mass Spectrometry.
PubMed ID: 34681573
Sequence Information:
- Length: 1073
- Mass: 109677
- Checksum: BFA471E36FCD06BD
- Sequence:
MHQPPESTAA AAAAADISAR KMAHPAMFPR RGSGSGSASA LNAAGTGVGS NATSSEDFPP PSLLQPPPPA ASSTSGPQPP PPQSLNLLSQ AQLQAQPLAP GGTQMKKKSG FQITSVTPAQ ISASISSNNS IAEDTESYDD LDESHTEDLS SSEILDVSLS RATDLGEPER SSSEETLNNF QEAETPGAVS PNQPHLPQPH LPHLPQQNVV INGNAHPHHL HHHHQIHHGH HLQHGHHHPS HVAVASASIT GGPPSSPVSR KLSTTGSSDS ITPVAPTSAV SSSGSPASVM TNMRAPSTTG GIGINSVTGT STVNNVNITA VGSFNPNVTS SMLGNVNIST SNIPSAAGVS VGPGVTSGVN VNILSGMGNG TISSSAAVSS VPNAAAGMTG GSVSSQQQQP TVNTSRFRVV KLDSSSEPFK KGRWTCTEFY EKENAVPATE GVLINKVVET VKQNPIEVTS ERESTSGSSV SSSVSTLSHY TESVGSGEMG APTVVVQQQQ QQQQQQQQQP ALQGVTLQQM DFGSTGPQSI PAVSIPQSIS QSQISQVQLQ SQELSYQQKQ GLQPVPLQAT MSAATGIQPS PVNVVGVTSA LGQQPSISSL AQPQLPYSQA APPVQTPLPG APPPQQLQYG QQQPMVSTQM APGHVKSVTQ NPASEYVQQQ PILQTAMSSG QPSSAGVGAG TTVIPVAQPQ GIQLPVQPTA VPAQPAGASV QPVGQAPAAV SAVPTGSQIA NIGQQANIPT AVQQPSTQVP PSVIQQGAPP SSQVVPPAQT GIIHQGVQTS APSLPQQLVI ASQSSLLTVP PQPQGVEPVA QGIVSQQLPA VSSLPSASSI SVTSQVSSTG PSGMPSAPTN LVPPQNIAQT PATQNGNLVQ SVSQPPLIAT NTNLPLAQQI PLSSTQFSAQ SLAQAIGSQI EDARRAAEPS LVGLPQTISG DSGGMSAVSD GSSSSLAASA SLFPLKVLPL TTPLVDGEDE SSSGASVVAI DNKIEQAMDL VKSHLMYAVR EEVEVLKEQI KELIEKNSQL EQENNLLKTL ASPEQLAQFQ AQLQTGSPPA TTQPQGTTQP PAQPASQGSG PTA
Genular Protein ID: 261532597
Symbol: A8K3Y6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 144
- Mass: 15668
- Checksum: 16A014D8A7D9C58E
- Sequence:
MKSQWCRPVA MDLGVYQLRH FSISFLSSLL GTENASVRLD NSSSGASVVA TDNKIEQAMD LVKSHLMYAV REEVEVLKEQ IKELIEKNSQ LEQENNLLKT LASPEQLAQF QAQLQTGSPP ATTQPQGTTQ PPAQPASQGS GPTA
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.