Details for: ACTN3

Gene ID: 89

Symbol: ACTN3

Ensembl ID: ENSG00000248746

Description: actinin alpha 3

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: neuroendocrine cell (CL0000165)
    Fold Change: 4.64
    Marker Score: 1,805
  • Cell Name: pericyte (CL0000669)
    Fold Change: 1.68
    Marker Score: 981
  • Cell Name: kidney proximal convoluted tubule epithelial cell (CL1000838)
    Fold Change: 1.63
    Marker Score: 3,365
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.62
    Marker Score: 1,176
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 1.27
    Marker Score: 861
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 1.19
    Marker Score: 492
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 1.17
    Marker Score: 2,215
  • Cell Name: goblet cell (CL0000160)
    Fold Change: 1.16
    Marker Score: 7,694
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.15
    Marker Score: 4,825
  • Cell Name: cell of skeletal muscle (CL0000188)
    Fold Change: 1.11
    Marker Score: 847
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 1.11
    Marker Score: 508
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,838
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 48,062
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1
    Marker Score: 514
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.99
    Marker Score: 467
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,409
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2,413
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.94
    Marker Score: 378
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.94
    Marker Score: 5,354
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.92
    Marker Score: 330
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.92
    Marker Score: 2,743
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,291
  • Cell Name: renal beta-intercalated cell (CL0002201)
    Fold Change: 0.84
    Marker Score: 267
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1,268
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.78
    Marker Score: 712
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.77
    Marker Score: 401
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 0.77
    Marker Score: 407
  • Cell Name: mast cell (CL0000097)
    Fold Change: 0.74
    Marker Score: 427
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.73
    Marker Score: 467
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.68
    Marker Score: 10,686
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 0.67
    Marker Score: 1,358
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 0.62
    Marker Score: 224
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.61
    Marker Score: 490
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 0.56
    Marker Score: 176
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.54
    Marker Score: 175
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 0.53
    Marker Score: 535
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 0.52
    Marker Score: 403
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 0.51
    Marker Score: 160
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.49
    Marker Score: 293
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 0.47
    Marker Score: 1,117
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 0.47
    Marker Score: 281
  • Cell Name: fast muscle cell (CL0000190)
    Fold Change: 0.45
    Marker Score: 136
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.44
    Marker Score: 211
  • Cell Name: epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 0.37
    Marker Score: 164
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: 0.32
    Marker Score: 518
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 0.3
    Marker Score: 77
  • Cell Name: neuronal receptor cell (CL0000006)
    Fold Change: 0.28
    Marker Score: 124
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.23
    Marker Score: 65
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.22
    Marker Score: 75
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.17
    Marker Score: 43
  • Cell Name: progenitor cell of endocrine pancreas (CL0002351)
    Fold Change: 0.16
    Marker Score: 34
  • Cell Name: podocyte (CL0000653)
    Fold Change: 0.14
    Marker Score: 51
  • Cell Name: CD16-positive, CD56-dim natural killer cell, human (CL0000939)
    Fold Change: 0.13
    Marker Score: 102
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: 0.12
    Marker Score: 195
  • Cell Name: B cell (CL0000236)
    Fold Change: 0.12
    Marker Score: 115
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.11
    Marker Score: 281
  • Cell Name: slow muscle cell (CL0000189)
    Fold Change: 0.11
    Marker Score: 37
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.11
    Marker Score: 38
  • Cell Name: leukocyte (CL0000738)
    Fold Change: 0.1
    Marker Score: 55
  • Cell Name: ciliated epithelial cell (CL0000067)
    Fold Change: 0.09
    Marker Score: 43
  • Cell Name: blood vessel endothelial cell (CL0000071)
    Fold Change: 0.09
    Marker Score: 89
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.08
    Marker Score: 227
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: 0.07
    Marker Score: 59
  • Cell Name: T cell (CL0000084)
    Fold Change: 0.07
    Marker Score: 120
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 0.07
    Marker Score: 28
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 0.07
    Marker Score: 60
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.06
    Marker Score: 15
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 0.06
    Marker Score: 40
  • Cell Name: fibroblast (CL0000057)
    Fold Change: 0.06
    Marker Score: 54
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.06
    Marker Score: 55
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.05
    Marker Score: 12
  • Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
    Fold Change: 0.05
    Marker Score: 80
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 0.05
    Marker Score: 52
  • Cell Name: type I enteroendocrine cell (CL0002277)
    Fold Change: 0.05
    Marker Score: 12
  • Cell Name: CD8-positive, alpha-beta cytotoxic T cell (CL0000794)
    Fold Change: 0.05
    Marker Score: 42
  • Cell Name: male germ cell (CL0000015)
    Fold Change: 0.05
    Marker Score: 13
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 0.04
    Marker Score: 12
  • Cell Name: macrophage (CL0000235)
    Fold Change: 0.04
    Marker Score: 47
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 0.04
    Marker Score: 65
  • Cell Name: plasma cell (CL0000786)
    Fold Change: 0.04
    Marker Score: 47
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: 0.04
    Marker Score: 27
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.04
    Marker Score: 20
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 0.04
    Marker Score: 35
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 0.04
    Marker Score: 10
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: 0.04
    Marker Score: 64
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: 0.04
    Marker Score: 50
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 0.04
    Marker Score: 19
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 0.04
    Marker Score: 45
  • Cell Name: subcutaneous fat cell (CL0002521)
    Fold Change: 0.04
    Marker Score: 13
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 0.03
    Marker Score: 11
  • Cell Name: retinal pigment epithelial cell (CL0002586)
    Fold Change: 0.03
    Marker Score: 10
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 0.03
    Marker Score: 14
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 0.03
    Marker Score: 12
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: 0.03
    Marker Score: 22
  • Cell Name: type A enteroendocrine cell (CL0002067)
    Fold Change: 0.03
    Marker Score: 13
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: 0.03
    Marker Score: 20
  • Cell Name: germ cell (CL0000586)
    Fold Change: 0.03
    Marker Score: 55
  • Cell Name: myelocyte (CL0002193)
    Fold Change: 0.03
    Marker Score: 13
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: 0.03
    Marker Score: 12
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.03
    Marker Score: 17

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** ACTN3 is a member of the actinin family of proteins, which are involved in maintaining the structural integrity of the cytoskeleton. This gene encodes a protein that is specifically localized to the Z-disc, a critical component of muscle fibers. The ACTN3 protein is known for its ability to bind to actin filaments, facilitating the organization and regulation of the cytoskeleton. Additionally, ACTN3 has been shown to interact with various signaling molecules, including integrins, which are essential for cell adhesion and signaling. **Pathways and Functions** ACTN3 is involved in numerous signaling pathways, including: 1. **Muscle contraction**: ACTN3 is essential for the regulation of muscle contraction, particularly in fast-twitch skeletal muscle fibers. 2. **Cell adhesion**: ACTN3 interacts with integrins, which are critical for cell adhesion and signaling. 3. **Bone mineralization**: ACTN3 has been shown to regulate bone mineralization, particularly in the context of bone maturation. 4. **Cell signaling**: ACTN3 interacts with various signaling molecules, including calcineurin and NFAT, which are involved in the regulation of muscle function and cell growth. 5. **Apoptosis**: ACTN3 has been implicated in the regulation of apoptotic processes, particularly in the context of muscle atrophy. **Clinical Significance** Dysregulation of ACTN3 has been associated with various diseases, including: 1. **Muscular dystrophy**: ACTN3 mutations have been linked to various forms of muscular dystrophy, including limb-girdle muscular dystrophy and Becker muscular dystrophy. 2. **Cardiovascular disorders**: ACTN3 has been implicated in the regulation of cardiac function and has been associated with various cardiovascular disorders, including heart failure and arrhythmias. 3. **Metabolic disorders**: ACTN3 has been shown to regulate glucose metabolism and has been implicated in the development of metabolic disorders, including type 2 diabetes. 4. **Cancer**: ACTN3 has been implicated in the regulation of cell growth and apoptosis, and has been associated with various types of cancer, including breast and colon cancer. In conclusion, ACTN3 is a critical gene that plays a central role in various cellular processes, including muscle contraction, cell adhesion, and signaling pathways. Its dysregulation has been associated with various diseases, highlighting the importance of this gene in maintaining physiological homeostasis. Further research is needed to fully understand the functional significance of ACTN3 and its role in various diseases.

Genular Protein ID: 1992642968

Symbol: ACTN3_HUMAN

Name: Alpha-actinin-3

UniProtKB Accession Codes:

Q08043 A6NP77 Q4KKV2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 4 CTD 1 ChEBI 6 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 4 EMDB 1 EPD 1 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 37 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 2 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 5 PDBsum 3 PIR 1 PRIDE 1 PRO 1 PROSITE 4 PROSITE-ProRule 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 2 RefSeq 2 SMART 4 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 SwissPalm 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1339456

Title: Cloning and characterization of two human skeletal muscle alpha-actinin genes located on chromosomes 1 and 11.

PubMed ID: 1339456

DOI: 10.1016/s0021-9258(19)50420-3

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11440986

Title: Differential expression of the actin-binding proteins, alpha-actinin-2 and -3, in different species: implications for the evolution of functional redundancy.

PubMed ID: 11440986

DOI: 10.1093/hmg/10.13.1335

PubMed ID: 11171996

Title: Myozenin: an alpha-actinin- and gamma-filamin-binding protein of skeletal muscle Z lines.

PubMed ID: 11171996

DOI: 10.1073/pnas.98.4.1595

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 15808860

Title: The crystal structure of the actin binding domain from alpha-actinin in its closed conformation: structural insight into phospholipid regulation of alpha-actinin.

PubMed ID: 15808860

DOI: 10.1016/j.jmb.2005.01.002

PubMed ID: 10192379

Title: A common nonsense mutation results in alpha-actinin-3 deficiency in the general population.

PubMed ID: 10192379

DOI: 10.1038/7675

Sequence Information:

  • Length: 901
  • Mass: 103241
  • Checksum: C49B7885E7E1EDA7
  • Sequence:
    • MMMVMQPEGL GAGEGRFAGG GGGGEYMEQE EDWDRDLLLD PAWEKQQRKT FTAWCNSHLR 
KAGTQIENIE EDFRNGLKLM LLLEVISGER LPRPDKGKMR FHKIANVNKA LDFIASKGVK 
LVSIGAEEIV DGNLKMTLGM IWTIILRFAI QDISVEETSA KEGLLLWCQR KTAPYRNVNV 
QNFHTSWKDG LALCALIHRH RPDLIDYAKL RKDDPIGNLN TAFEVAEKYL DIPKMLDAED 
IVNTPKPDEK AIMTYVSCFY HAFAGAEQAE TAANRICKVL AVNQENEKLM EEYEKLASEL 
LEWIRRTVPW LENRVGEPSM SAMQRKLEDF RDYRRLHKPP RIQEKCQLEI NFNTLQTKLR 
LSHRPAFMPS EGKLVSDIAN AWRGLEQVEK GYEDWLLSEI RRLQRLQHLA EKFRQKASLH 
EAWTRGKEEM LSQRDYDSAL LQEVRALLRR HEAFESDLAA HQDRVEHIAA LAQELNELDY 
HEAASVNSRC QAICDQWDNL GTLTQKRRDA LERMEKLLET IDRLQLEFAR RAAPFNNWLD 
GAVEDLQDVW LVHSVEETQS LLTAHDQFKA TLPEADRERG AIMGIQGEIQ KICQTYGLRP 
CSTNPYITLS PQDINTKWDM VRKLVPSCDQ TLQEELARQQ VNERLRRQFA AQANAIGPWI 
QAKVEEVGRL AAGLAGSLEE QMAGLRQQEQ NIINYKTNID RLEGDHQLLQ ESLVFDNKHT 
VYSMEHIRVG WEQLLTSIAR TINEVENQVL TRDAKGLSQE QLNEFRASFN HFDRKQNGMM 
EPDDFRACLI SMGYDLGEVE FARIMTMVDP NAAGVVTFQA FIDFMTRETA ETDTTEQVVA 
SFKILAGDKN YITPEELRRE LPAKQAEYCI RRMVPYKGSG APAGALDYVA FSSALYGESD 
L

Genular Protein ID: 148560350

Symbol: B4DZQ2_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DZQ2

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 4 CTD 1 DNASU 1 EMBL 2 GO 3 Gene3D 3 GenomeRNAi 1 InterPro 8 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 5 PeptideAtlas 1 Pfam 3 RefSeq 2 SAM 2 SMART 4 SUPFAM 3

Sequence Information:

  • Length: 944
  • Mass: 107654
  • Checksum: 481D5878716F7DAF
  • Sequence:
    • MGIGLCVPPA RCWKRLTRSS RGQPLERPAA TIIIGLSIVE RSKQTQRGPV DFSRSHSAPA 
AEQECKPRIS AARSTPAPPS PAVPGFRTTP CQTFTAWCNS HLRKAGTQIE NIEEDFRNGL 
KLMLLLEVIS GERLPRPDKG KMRFHKIANV NKALDFIASK GVKLVSIGAE EIVDGNLKMT 
LGMIWTIILR FAIQDISVEE TSAKEGLLLW CQRKTAPYRN VNVQNFHTSW KDGLALCALI 
HRHRPDLIDY AKLRKDDPIG NLNTAFEVAE KYLDIPKMLD AEDIVNTPKP DEKAIMTYVS 
CFYHAFAGAE QAETAANRIC KVLAVNQENE KLMEEYEKLA SELLEWIRRT VPWLENRVGE 
PSMSAMQRKL EDFRDYRRLH KPPRIQEKCQ LEINFNTLQT KLRLSHRPAF MPSEGKLVSD 
IANAWRGLEQ VEKGYEDWLL SEIRRLQRLQ HLAEKFRQKA SLHEAWTRGK EEMLSQRDYD 
SALLQEVRAL LRRHEAFESD LAAHQDRVEH IAALAQELNE LDYHEAASVN SRCQAICDQW 
DNLGTLTQKR RDALERMEKL LETIDQLQLE FARQAAPFNN WLDGAVEDLQ DVWLVHSVEE 
TQSLLTAHDQ FKATLPEADR ERGAIMGIQG EIQKICQTYG LRPCSTNPYI TLSPQDINTK 
WDMVRKLVPS RDQTLQEELA RQQVNERLRR QFAAQANAIG PWIQAKVEEV GRLAAGLAGS 
LEEQMAGLRQ QEQNIINYKT NIDRLEGDHQ LLQESLVFDN KHTVYSMEHI RVGWEQLLTS 
IARTINEVEN QVLTRDAKGL SQEQLNEFRA SFNHFDRKRN GMMEPDDFRA CLISMGYDLG 
EVEFARIMTM VDPNAAGVVT FQAFIDFMTR ETAETDTTEQ VVASFKILAG DKNYITPEEL 
RRELPAKQAE YCIRRMVPYK GSGAPAGALD YVAFSSALYG ESDL

Genular Protein ID: 2684242458

Symbol: A0A087WSZ2_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087WSZ2

Database IDs:

ARBA 4 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 4 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 3 GeneTree 1 GenomeRNAi 1 HGNC 1 IntAct 1 InterPro 8 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRIDE 1 PROSITE 5 Pfam 3 Proteomes 2 RefSeq 1 SAM 2 SMART 4 SMR 1 SUPFAM 3 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

Sequence Information:

  • Length: 944
  • Mass: 107629
  • Checksum: D8A7BE9FA569BD3D
  • Sequence:
    • MGIGLCVPPA RCWKRLTRSS RGQPLERPAA TIIIGLSIVE RSKQTQRGPV DFSRSHSAPA 
AEQECKPRIS AARSTPAPPS PAVPGFRTTP CQTFTAWCNS HLRKAGTQIE NIEEDFRNGL 
KLMLLLEVIS GERLPRPDKG KMRFHKIANV NKALDFIASK GVKLVSIGAE EIVDGNLKMT 
LGMIWTIILR FAIQDISVEE TSAKEGLLLW CQRKTAPYRN VNVQNFHTSW KDGLALCALI 
HRHRPDLIDY AKLRKDDPIG NLNTAFEVAE KYLDIPKMLD AEDIVNTPKP DEKAIMTYVS 
CFYHAFAGAE QAETAANRIC KVLAVNQENE KLMEEYEKLA SELLEWIRRT VPWLENRVGE 
PSMSAMQRKL EDFRDYRRLH KPPRIQEKCQ LEINFNTLQT KLRLSHRPAF MPSEGKLVSD 
IANAWRGLEQ VEKGYEDWLL SEIRRLQRLQ HLAEKFRQKA SLHEAWTRGK EEMLSQRDYD 
SALLQEVRAL LRRHEAFESD LAAHQDRVEH IAALAQELNE LDYHEAASVN SRCQAICDQW 
DNLGTLTQKR RDALERMEKL LETIDRLQLE FARRAAPFNN WLDGAVEDLQ DVWLVHSVEE 
TQSLLTAHDQ FKATLPEADR ERGAIMGIQG EIQKICQTYG LRPCSTNPYI TLSPQDINTK 
WDMVRKLVPS CDQTLQEELA RQQVNERLRR QFAAQANAIG PWIQAKVEEV GRLAAGLAGS 
LEEQMAGLRQ QEQNIINYKT NIDRLEGDHQ LLQESLVFDN KHTVYSMEHI RVGWEQLLTS 
IARTINEVEN QVLTRDAKGL SQEQLNEFRA SFNHFDRKQN GMMEPDDFRA CLISMGYDLG 
EVEFARIMTM VDPNAAGVVT FQAFIDFMTR ETAETDTTEQ VVASFKILAG DKNYITPEEL 
RRELPAKQAE YCIRRMVPYK GSGAPAGALD YVAFSSALYG ESDL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.