Details for: LINC02914

Gene ID: 283598

Symbol: LINC02914

Ensembl ID: ENSG00000176605

Description: long intergenic non-protein coding RNA 2914

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: 0.2172
    Cell Significance Index: 2.7900
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.1575
    Cell Significance Index: 1.6300
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: 0.1484
    Cell Significance Index: 2.1300
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 0.0889
    Cell Significance Index: 1.1300
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 0.0452
    Cell Significance Index: 0.7600
  • Cell Name: stromal cell (CL0000499)
    Fold Change: 0.0382
    Cell Significance Index: 0.3900
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 0.0344
    Cell Significance Index: 0.4000
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 0.0182
    Cell Significance Index: 0.4500
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.0158
    Cell Significance Index: 0.4100
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 0.0098
    Cell Significance Index: 0.0700
  • Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
    Fold Change: 0.0083
    Cell Significance Index: 0.0900
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 0.0050
    Cell Significance Index: 0.0600
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: 0.0030
    Cell Significance Index: 0.0400
  • Cell Name: pulmonary alveolar type 1 cell (CL0002062)
    Fold Change: 0.0018
    Cell Significance Index: 0.0200
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: 0.0016
    Cell Significance Index: 0.0200
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: 0.0009
    Cell Significance Index: 0.0100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0008
    Cell Significance Index: 0.1700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0002
    Cell Significance Index: 0.0700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0001
    Cell Significance Index: 0.0200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0000
    Cell Significance Index: 0.0800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0000
    Cell Significance Index: 0.0600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0001
    Cell Significance Index: -0.1600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0001
    Cell Significance Index: -0.0900
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0001
    Cell Significance Index: 0.0000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0003
    Cell Significance Index: -0.2000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0004
    Cell Significance Index: -0.2800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0004
    Cell Significance Index: -0.2200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0005
    Cell Significance Index: -0.2200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0005
    Cell Significance Index: -0.1400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0007
    Cell Significance Index: -0.1000
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0009
    Cell Significance Index: -0.0500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0011
    Cell Significance Index: -0.1300
  • Cell Name: OFF-bipolar cell (CL0000750)
    Fold Change: -0.0011
    Cell Significance Index: -0.0100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0016
    Cell Significance Index: -0.1100
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0017
    Cell Significance Index: -0.0600
  • Cell Name: vascular associated smooth muscle cell (CL0000359)
    Fold Change: -0.0019
    Cell Significance Index: -0.0200
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: -0.0019
    Cell Significance Index: -0.0200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0020
    Cell Significance Index: -0.2100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0021
    Cell Significance Index: -0.0600
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0023
    Cell Significance Index: -0.0500
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -0.0023
    Cell Significance Index: -0.0300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0024
    Cell Significance Index: -0.0700
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.0026
    Cell Significance Index: -0.0700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0027
    Cell Significance Index: -0.1200
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0028
    Cell Significance Index: -0.0900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0029
    Cell Significance Index: -0.1100
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -0.0030
    Cell Significance Index: -0.0400
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0034
    Cell Significance Index: -0.0500
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0035
    Cell Significance Index: -0.1200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0037
    Cell Significance Index: -0.2100
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0042
    Cell Significance Index: -0.0900
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: -0.0046
    Cell Significance Index: -0.0400
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.0048
    Cell Significance Index: -0.1000
  • Cell Name: secretory cell (CL0000151)
    Fold Change: -0.0048
    Cell Significance Index: -0.0300
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0051
    Cell Significance Index: -0.0700
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.0051
    Cell Significance Index: -0.1600
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0052
    Cell Significance Index: -0.1300
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0060
    Cell Significance Index: -0.1300
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.0061
    Cell Significance Index: -0.0800
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.0063
    Cell Significance Index: -0.1800
  • Cell Name: neuroendocrine cell (CL0000165)
    Fold Change: -0.0063
    Cell Significance Index: -0.0800
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: -0.0067
    Cell Significance Index: -0.0900
  • Cell Name: central memory CD4-positive, alpha-beta T cell (CL0000904)
    Fold Change: -0.0069
    Cell Significance Index: -0.0600
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.0071
    Cell Significance Index: -0.1400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0073
    Cell Significance Index: -0.2000
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.0075
    Cell Significance Index: -0.1500
  • Cell Name: melanocyte (CL0000148)
    Fold Change: -0.0075
    Cell Significance Index: -0.0700
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0080
    Cell Significance Index: -0.1600
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0081
    Cell Significance Index: -0.1600
  • Cell Name: myoepithelial cell (CL0000185)
    Fold Change: -0.0081
    Cell Significance Index: -0.0900
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.0082
    Cell Significance Index: -0.2000
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.0084
    Cell Significance Index: -0.1200
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: -0.0087
    Cell Significance Index: -0.1200
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.0087
    Cell Significance Index: -0.1700
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: -0.0089
    Cell Significance Index: -0.1000
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: -0.0092
    Cell Significance Index: -0.1000
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.0095
    Cell Significance Index: -0.2300
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0096
    Cell Significance Index: -0.2000
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.0097
    Cell Significance Index: -0.1400
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.0098
    Cell Significance Index: -0.1700
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: -0.0102
    Cell Significance Index: -0.1100
  • Cell Name: double negative thymocyte (CL0002489)
    Fold Change: -0.0110
    Cell Significance Index: -0.1300
  • Cell Name: type II muscle cell (CL0002212)
    Fold Change: -0.0112
    Cell Significance Index: -0.1800
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: -0.0112
    Cell Significance Index: -0.1300
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.0115
    Cell Significance Index: -0.1600
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.0118
    Cell Significance Index: -0.1700
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.0119
    Cell Significance Index: -0.1400
  • Cell Name: thymocyte (CL0000893)
    Fold Change: -0.0119
    Cell Significance Index: -0.1500
  • Cell Name: lung ciliated cell (CL1000271)
    Fold Change: -0.0123
    Cell Significance Index: -0.1200
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.0127
    Cell Significance Index: -0.1200
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0129
    Cell Significance Index: -0.1400
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.0130
    Cell Significance Index: -0.1600
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.0130
    Cell Significance Index: -0.2200
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: -0.0130
    Cell Significance Index: -0.1700
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.0135
    Cell Significance Index: -0.1800
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.0135
    Cell Significance Index: -0.1800
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.0135
    Cell Significance Index: -0.1700
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: -0.0138
    Cell Significance Index: -0.1600
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: -0.0138
    Cell Significance Index: -0.1500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Location and Expression:** LINC02914 is located in the intergenic region of the genome, and its expression is restricted to specific cell types, including progenitor cells, endothelial cells, and stem cells. 2. **Function:** LINC02914 has been shown to regulate cellular processes, including cell migration, differentiation, and survival. 3. **Stability:** LINC02914 is a stable transcript that can persist in the cell for extended periods. 4. **Regulation:** LINC02914 is regulated by various transcription factors, including transcription factor YBX1, which is involved in the regulation of cell growth and differentiation. **Pathways and Functions:** LINC02914 has been implicated in several cellular pathways, including: 1. **Cell Migration:** LINC02914 has been shown to regulate cell migration by interacting with the cytoskeleton and modulating the activity of signaling molecules. 2. **Differentiation:** LINC02914 has been implicated in the regulation of cell differentiation by interacting with transcription factors and modulating the expression of target genes. 3. **Survival:** LINC02914 has been shown to regulate cell survival by interacting with pro-survival and pro-apoptotic signaling molecules. 4. **Cytoskeleton Organization:** LINC02914 has been implicated in the regulation of cytoskeleton organization by interacting with actin-binding proteins and modulating the activity of motor proteins. **Clinical Significance:** LINC02914 has been implicated in various clinical disorders, including: 1. **Cancer:** LINC02914 has been shown to be overexpressed in various types of cancer, including breast, lung, and colon cancer. Its overexpression has been associated with poor prognosis and increased metastatic potential. 2. **Neurological Disorders:** LINC02914 has been implicated in neurological disorders, including Alzheimer's disease, Parkinson's disease, and multiple sclerosis. Its dysregulation has been associated with cognitive decline and motor dysfunction. 3. **Cardiovascular Diseases:** LINC02914 has been shown to be overexpressed in cardiovascular diseases, including atherosclerosis and cardiac hypertrophy. Its overexpression has been associated with increased inflammation and cardiac remodeling. 4. **Immunological Disorders:** LINC02914 has been implicated in immunological disorders, including autoimmune diseases and inflammatory bowel disease. Its dysregulation has been associated with impaired immune function and increased inflammation. In conclusion, LINC02914 is a long intergenic non-protein coding RNA that plays a crucial role in regulating cellular processes, including cell migration, differentiation, and survival. Its dysregulation has been implicated in various clinical disorders, highlighting its potential as a biomarker and therapeutic target. Further studies are needed to fully understand the mechanisms of LINC02914 and its implications in human disease.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.