Details for: SNORD14A

Gene ID: 26822

Symbol: SNORD14A

Ensembl ID: ENSG00000272034

Description: small nucleolar RNA, C/D box 14A

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.3859
    Cell Significance Index: 4.6000
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: 0.3797
    Cell Significance Index: 4.2900
  • Cell Name: muscle cell (CL0000187)
    Fold Change: 0.1197
    Cell Significance Index: 1.1500
  • Cell Name: chondrocyte (CL0000138)
    Fold Change: 0.1041
    Cell Significance Index: 1.2000
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: 0.0765
    Cell Significance Index: 0.7400
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.0703
    Cell Significance Index: 1.0000
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 0.0424
    Cell Significance Index: 1.0600
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: 0.0214
    Cell Significance Index: 0.2600
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 0.0085
    Cell Significance Index: 0.0900
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.0050
    Cell Significance Index: 0.1100
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 0.0050
    Cell Significance Index: 0.0700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0032
    Cell Significance Index: -0.1500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0035
    Cell Significance Index: -1.0200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0132
    Cell Significance Index: -0.1800
  • Cell Name: retinal pigment epithelial cell (CL0002586)
    Fold Change: -0.0144
    Cell Significance Index: -0.1600
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0179
    Cell Significance Index: -0.9300
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.0203
    Cell Significance Index: -0.3500
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: -0.0208
    Cell Significance Index: -0.2600
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0209
    Cell Significance Index: -0.3100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0219
    Cell Significance Index: -1.1400
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.0253
    Cell Significance Index: -0.3800
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.0270
    Cell Significance Index: -0.9900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0299
    Cell Significance Index: -0.8000
  • Cell Name: amacrine cell (CL0000561)
    Fold Change: -0.0447
    Cell Significance Index: -0.5600
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0466
    Cell Significance Index: -1.3400
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: -0.0494
    Cell Significance Index: -0.3800
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.0530
    Cell Significance Index: -0.9000
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0551
    Cell Significance Index: -0.6000
  • Cell Name: pericyte (CL0000669)
    Fold Change: -0.0625
    Cell Significance Index: -0.7500
  • Cell Name: erythroblast (CL0000765)
    Fold Change: -0.0646
    Cell Significance Index: -0.7700
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.0654
    Cell Significance Index: -0.8600
  • Cell Name: medium spiny neuron (CL1001474)
    Fold Change: -0.0660
    Cell Significance Index: -0.8900
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: -0.0663
    Cell Significance Index: -0.7800
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.0666
    Cell Significance Index: -0.8400
  • Cell Name: retina horizontal cell (CL0000745)
    Fold Change: -0.0685
    Cell Significance Index: -0.8600
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.0715
    Cell Significance Index: -0.9500
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.0727
    Cell Significance Index: -0.8700
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: -0.0729
    Cell Significance Index: -0.7600
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: -0.0735
    Cell Significance Index: -1.0000
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.0754
    Cell Significance Index: -0.8000
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: -0.0757
    Cell Significance Index: -0.8400
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.0782
    Cell Significance Index: -1.0200
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.0782
    Cell Significance Index: -0.9300
  • Cell Name: neutrophil (CL0000775)
    Fold Change: -0.0784
    Cell Significance Index: -0.9800
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: -0.0786
    Cell Significance Index: -0.8700
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.0787
    Cell Significance Index: -0.6500
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: -0.0794
    Cell Significance Index: -0.9600
  • Cell Name: acinar cell (CL0000622)
    Fold Change: -0.0796
    Cell Significance Index: -1.0000
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.0797
    Cell Significance Index: -0.9800
  • Cell Name: secretory cell (CL0000151)
    Fold Change: -0.0808
    Cell Significance Index: -0.5600
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: -0.0816
    Cell Significance Index: -0.9700
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: -0.0818
    Cell Significance Index: -0.9500
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.0826
    Cell Significance Index: -0.9800
  • Cell Name: capillary endothelial cell (CL0002144)
    Fold Change: -0.0836
    Cell Significance Index: -0.9500
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: -0.0843
    Cell Significance Index: -1.1000
  • Cell Name: monocyte (CL0000576)
    Fold Change: -0.0843
    Cell Significance Index: -0.9700
  • Cell Name: cell of skeletal muscle (CL0000188)
    Fold Change: -0.0843
    Cell Significance Index: -1.0800
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: -0.0844
    Cell Significance Index: -0.9800
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.0848
    Cell Significance Index: -0.9700
  • Cell Name: neuronal brush cell (CL0000555)
    Fold Change: -0.0848
    Cell Significance Index: -0.9200
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.0851
    Cell Significance Index: -1.0000
  • Cell Name: B cell (CL0000236)
    Fold Change: -0.0855
    Cell Significance Index: -1.0100
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: -0.0859
    Cell Significance Index: -1.0100
  • Cell Name: regulatory T cell (CL0000815)
    Fold Change: -0.0862
    Cell Significance Index: -1.0000
  • Cell Name: brain vascular cell (CL4023072)
    Fold Change: -0.0875
    Cell Significance Index: -1.0000
  • Cell Name: pulmonary alveolar type 1 cell (CL0002062)
    Fold Change: -0.0879
    Cell Significance Index: -0.9700
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: -0.0879
    Cell Significance Index: -0.8700
  • Cell Name: mesothelial cell (CL0000077)
    Fold Change: -0.0880
    Cell Significance Index: -1.0700
  • Cell Name: non-classical monocyte (CL0000875)
    Fold Change: -0.0885
    Cell Significance Index: -0.9800
  • Cell Name: peptic cell (CL0000155)
    Fold Change: -0.0911
    Cell Significance Index: -0.8100
  • Cell Name: granulocyte (CL0000094)
    Fold Change: -0.0912
    Cell Significance Index: -1.1000
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.0914
    Cell Significance Index: -0.9800
  • Cell Name: goblet cell (CL0000160)
    Fold Change: -0.0929
    Cell Significance Index: -0.8400
  • Cell Name: club cell (CL0000158)
    Fold Change: -0.0936
    Cell Significance Index: -1.0200
  • Cell Name: glial cell (CL0000125)
    Fold Change: -0.0940
    Cell Significance Index: -1.0300
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: -0.0940
    Cell Significance Index: -0.9400
  • Cell Name: vein endothelial cell (CL0002543)
    Fold Change: -0.0941
    Cell Significance Index: -1.0200
  • Cell Name: endothelial cell of artery (CL1000413)
    Fold Change: -0.0949
    Cell Significance Index: -1.0000
  • Cell Name: macrophage (CL0000235)
    Fold Change: -0.0950
    Cell Significance Index: -0.9700
  • Cell Name: erythroid lineage cell (CL0000764)
    Fold Change: -0.0952
    Cell Significance Index: -1.0500
  • Cell Name: stem cell (CL0000034)
    Fold Change: -0.0958
    Cell Significance Index: -0.7000
  • Cell Name: mucus secreting cell (CL0000319)
    Fold Change: -0.0959
    Cell Significance Index: -0.9800
  • Cell Name: melanocyte (CL0000148)
    Fold Change: -0.0960
    Cell Significance Index: -0.9000
  • Cell Name: stromal cell (CL0000499)
    Fold Change: -0.0964
    Cell Significance Index: -0.9900
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: -0.0964
    Cell Significance Index: -0.9400
  • Cell Name: plasma cell (CL0000786)
    Fold Change: -0.0971
    Cell Significance Index: -1.0900
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: -0.0980
    Cell Significance Index: -0.9900
  • Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
    Fold Change: -0.0985
    Cell Significance Index: -1.0200
  • Cell Name: conventional dendritic cell (CL0000990)
    Fold Change: -0.0990
    Cell Significance Index: -1.1700
  • Cell Name: alternatively activated macrophage (CL0000890)
    Fold Change: -0.0991
    Cell Significance Index: -0.9200
  • Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
    Fold Change: -0.0994
    Cell Significance Index: -0.9300
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.1002
    Cell Significance Index: -0.9500
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: -0.1004
    Cell Significance Index: -0.8900
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: -0.1008
    Cell Significance Index: -0.9900
  • Cell Name: lung ciliated cell (CL1000271)
    Fold Change: -0.1012
    Cell Significance Index: -0.9900
  • Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
    Fold Change: -0.1013
    Cell Significance Index: -0.9600
  • Cell Name: blood vessel smooth muscle cell (CL0019018)
    Fold Change: -0.1017
    Cell Significance Index: -0.9600
  • Cell Name: respiratory basal cell (CL0002633)
    Fold Change: -0.1024
    Cell Significance Index: -1.0100
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: -0.1025
    Cell Significance Index: -1.0400
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: -0.1029
    Cell Significance Index: -1.1600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **C/D box snoRNA:** SNORD14A belongs to the C/D box snoRNA family, which is characterized by the presence of a C/D box motif in their 5' stem. 2. **Small nucleolar RNA:** SNORD14A is a small RNA molecule, approximately 70-100 nucleotides in length, which is involved in various cellular processes. 3. **Significant expression:** SNORD14A is significantly expressed in various cell types, suggesting its involvement in multiple cellular processes. 4. **RNA processing regulation:** SNORD14A is implicated in regulating RNA processing, including pre-rRNA processing and modification. **Pathways and Functions:** 1. **Nucleolus:** SNORD14A is involved in regulating nucleolar function, including pre-rRNA processing and modification. 2. **RNA processing:** SNORD14A plays a crucial role in regulating RNA processing, including pre-rRNA processing and modification. 3. **Cell development:** SNORD14A is involved in regulating cell development, including the development of pericytes, cardiac endothelial cells, and immune cells. 4. **Cell differentiation:** SNORD14A is implicated in cell differentiation, including the differentiation of cardiac muscle myoblasts and smooth muscle myoblasts. **Clinical Significance:** 1. **Immunological disorders:** SNORD14A dysregulation has been implicated in various immunological disorders, including autoimmune diseases and immunodeficiency syndromes. 2. **Cardiac diseases:** SNORD14A dysregulation has been linked to cardiac diseases, including heart failure and cardiac arrhythmias. 3. **Cancer:** SNORD14A dysregulation has been implicated in various cancers, including leukemia and lymphoma. 4. **Neurological disorders:** SNORD14A dysregulation has been linked to neurological disorders, including Parkinson's disease and Alzheimer's disease. In conclusion, SNORD14A is a small nucleolar RNA that plays a crucial role in regulating RNA processing, cell development, and cell differentiation. Its dysregulation has been implicated in various immunological, cardiac, and neurological disorders, highlighting its potential as a therapeutic target for disease treatment. Further research is necessary to fully elucidate the role of SNORD14A in human disease and to explore its potential as a therapeutic target.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.