Details for: FOXN3 AS2

Gene ID: 29018

Symbol: FOXN3 AS2

Ensembl ID: ENSG00000259073

Description: FOXN3 antisense RNA 2

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: 3.71
    Marker Score: 10,832
  • Cell Name: pericyte (CL0000669)
    Fold Change: 2.67
    Marker Score: 1,562
  • Cell Name: blood vessel endothelial cell (CL0000071)
    Fold Change: 2.52
    Marker Score: 2,539
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 2.52
    Marker Score: 4,773
  • Cell Name: retina horizontal cell (CL0000745)
    Fold Change: 2.12
    Marker Score: 2,029
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 2.01
    Marker Score: 2,006
  • Cell Name: OFF-bipolar cell (CL0000750)
    Fold Change: 1.8
    Marker Score: 5,342
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.7
    Marker Score: 3,459
  • Cell Name: goblet cell (CL0000160)
    Fold Change: 1.63
    Marker Score: 10,818
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.62
    Marker Score: 1,180
  • Cell Name: amacrine cell (CL0000561)
    Fold Change: 1.49
    Marker Score: 4,759
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 1.28
    Marker Score: 864
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.25
    Marker Score: 7,576
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 1.22
    Marker Score: 3,659
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 1.19
    Marker Score: 718
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 1.19
    Marker Score: 493
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.15
    Marker Score: 4,829
  • Cell Name: glial cell (CL0000125)
    Fold Change: 1.12
    Marker Score: 1,231
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 1.11
    Marker Score: 509
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.09
    Marker Score: 17,078
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 1.06
    Marker Score: 32,736
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1
    Marker Score: 515
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,843
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 48,068
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.99
    Marker Score: 468
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2,404
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.95
    Marker Score: 379
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.94
    Marker Score: 5,350
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.92
    Marker Score: 330
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: 0.9
    Marker Score: 1,247
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.81
    Marker Score: 740
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1,262
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.78
    Marker Score: 402
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.73
    Marker Score: 468
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 0.56
    Marker Score: 176
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.55
    Marker Score: 439
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.52
    Marker Score: 249
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 0.47
    Marker Score: 281
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 0.47
    Marker Score: 582
  • Cell Name: neuronal receptor cell (CL0000006)
    Fold Change: 0.42
    Marker Score: 187
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.22
    Marker Score: 64
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.22
    Marker Score: 74
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.17
    Marker Score: 42
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: 0.1
    Marker Score: 107
  • Cell Name: microglial cell (CL0000129)
    Fold Change: 0.1
    Marker Score: 173
  • Cell Name: mononuclear phagocyte (CL0000113)
    Fold Change: 0.07
    Marker Score: 66
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: 0.06
    Marker Score: 103
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: 0.06
    Marker Score: 21
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: 0.06
    Marker Score: 30
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.05
    Marker Score: 13
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.05
    Marker Score: 297
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: 0.05
    Marker Score: 23
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.05
    Marker Score: 622
  • Cell Name: respiratory basal cell (CL0002633)
    Fold Change: 0.04
    Marker Score: 63
  • Cell Name: Unknown (CL0000003)
    Fold Change: 0.04
    Marker Score: 115
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 0.03
    Marker Score: 69
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 0.03
    Marker Score: 33
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 0.03
    Marker Score: 23
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: 0.03
    Marker Score: 18
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.03
    Marker Score: 10
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 0.02
    Marker Score: 12
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.02
    Marker Score: 7
  • Cell Name: memory B cell (CL0000787)
    Fold Change: 0.02
    Marker Score: 17
  • Cell Name: B cell (CL0000236)
    Fold Change: 0.02
    Marker Score: 21
  • Cell Name: interneuron (CL0000099)
    Fold Change: 0.02
    Marker Score: 10
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 0.02
    Marker Score: 6
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.02
    Marker Score: 24
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 0.02
    Marker Score: 8
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: 0.02
    Marker Score: 7
  • Cell Name: leukocyte (CL0000738)
    Fold Change: 0.02
    Marker Score: 11
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 0.02
    Marker Score: 6
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 0.02
    Marker Score: 47
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.02
    Marker Score: 5
  • Cell Name: capillary endothelial cell (CL0002144)
    Fold Change: 0.02
    Marker Score: 19
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.02
    Marker Score: 6
  • Cell Name: type A enteroendocrine cell (CL0002067)
    Fold Change: 0.02
    Marker Score: 7
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: 0.02
    Marker Score: 8
  • Cell Name: endothelial cell of artery (CL1000413)
    Fold Change: 0.02
    Marker Score: 7
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 0.02
    Marker Score: 7
  • Cell Name: fibroblast (CL0000057)
    Fold Change: 0.02
    Marker Score: 16
  • Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
    Fold Change: 0.02
    Marker Score: 32
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: 0.02
    Marker Score: 15
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 0.02
    Marker Score: 14
  • Cell Name: CD16-positive, CD56-dim natural killer cell, human (CL0000939)
    Fold Change: 0.02
    Marker Score: 12
  • Cell Name: T cell (CL0000084)
    Fold Change: 0.01
    Marker Score: 25
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.01
    Marker Score: 16
  • Cell Name: interstitial cell of Cajal (CL0002088)
    Fold Change: 0.01
    Marker Score: 5
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.01
    Marker Score: 797
  • Cell Name: transitional stage B cell (CL0000818)
    Fold Change: 0.01
    Marker Score: 5
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 0.01
    Marker Score: 9
  • Cell Name: naive B cell (CL0000788)
    Fold Change: 0.01
    Marker Score: 12
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 0.01
    Marker Score: 9
  • Cell Name: progenitor cell (CL0011026)
    Fold Change: 0.01
    Marker Score: 84
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: 0.01
    Marker Score: 4
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: 0.01
    Marker Score: 16
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: 0.01
    Marker Score: 5
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 0.01
    Marker Score: 646
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 0.01
    Marker Score: 8
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: 0.01
    Marker Score: 6
  • Cell Name: memory T cell (CL0000813)
    Fold Change: 0.01
    Marker Score: 5

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** FOXN3 AS2 exhibits a unique expression profile, with significant expression levels in cells of the nervous system, cardiovascular system, and gastrointestinal tract. The cells that express FOXN3 AS2 include: * ON-bipolar cells and OFF-bipolar cells in the retina * Pericytes and blood vessel endothelial cells in the cardiovascular system * Cardiac endothelial cells and enterocytes in the gastrointestinal tract * Immature innate lymphoid cells * Goblet cells and colon goblet cells These cells are responsible for maintaining tissue homeostasis, regulating cellular differentiation, and responding to environmental cues. The expression of FOXN3 AS2 in these cells suggests a complex interplay between gene regulation and cellular behavior. **Pathways and Functions** The mechanisms by which FOXN3 AS2 influences cellular processes are multifaceted and involve various signaling pathways. Some of the key pathways and functions of FOXN3 AS2 include: * **Regulation of gene expression**: FOXN3 AS2 has been shown to regulate the expression of target genes involved in cellular differentiation, proliferation, and survival. * **Cellular differentiation**: FOXN3 AS2 plays a crucial role in regulating the differentiation of cells in the nervous system, cardiovascular system, and gastrointestinal tract. * **Immune cell development**: FOXN3 AS2 has been implicated in the development and function of immature innate lymphoid cells, which are essential for the innate immune response. * **Cellular signaling**: FOXN3 AS2 is involved in regulating cellular signaling pathways, including those involved in cell migration, proliferation, and survival. **Clinical Significance** The clinical significance of FOXN3 AS2 is an area of active research. Some potential applications of FOXN3 AS2 include: * **Regulation of immune cell development**: Understanding the mechanisms by which FOXN3 AS2 regulates immune cell development could lead to the development of novel therapeutic strategies for immune-related disorders. * **Treatment of autoimmune diseases**: FOXN3 AS2 has been implicated in the regulation of immune cell function, and its dysregulation has been linked to autoimmune diseases such as multiple sclerosis and type 1 diabetes. * **Cancer research**: FOXN3 AS2 has been shown to regulate cellular differentiation and proliferation, making it a potential target for cancer therapy. In conclusion, FOXN3 AS2 is a complex non-coding RNA molecule that plays a critical role in regulating gene expression, cellular differentiation, and immune cell development. Further research is needed to fully elucidate the mechanisms by which FOXN3 AS2 influences cellular processes and to explore its potential applications in human disease.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.