Details for: RPSAP13

Gene ID: 3923

Symbol: RPSAP13

Ensembl ID: ENSG00000233924

Description: ribosomal protein SA pseudogene 13

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: 0.4711
    Cell Significance Index: 6.1600
  • Cell Name: granulocyte (CL0000094)
    Fold Change: 0.1315
    Cell Significance Index: 1.5900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.0572
    Cell Significance Index: 0.7800
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.0415
    Cell Significance Index: 0.4300
  • Cell Name: erythroblast (CL0000765)
    Fold Change: 0.0415
    Cell Significance Index: 0.5000
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.0406
    Cell Significance Index: 0.6000
  • Cell Name: pulmonary alveolar type 2 cell (CL0002063)
    Fold Change: 0.0048
    Cell Significance Index: 0.0400
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.0050
    Cell Significance Index: -0.1200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0146
    Cell Significance Index: -1.6700
  • Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
    Fold Change: -0.0270
    Cell Significance Index: -0.2800
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0309
    Cell Significance Index: -0.6400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0369
    Cell Significance Index: -1.7200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0444
    Cell Significance Index: -2.0100
  • Cell Name: plasma cell (CL0000786)
    Fold Change: -0.0510
    Cell Significance Index: -0.5700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0519
    Cell Significance Index: -1.3900
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0526
    Cell Significance Index: -1.3400
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.0541
    Cell Significance Index: -0.7500
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.0594
    Cell Significance Index: -1.0200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0684
    Cell Significance Index: -1.9700
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.0706
    Cell Significance Index: -0.8400
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0712
    Cell Significance Index: -1.5600
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0734
    Cell Significance Index: -0.8000
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: -0.0775
    Cell Significance Index: -0.9000
  • Cell Name: regulatory T cell (CL0000815)
    Fold Change: -0.0810
    Cell Significance Index: -0.9400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0826
    Cell Significance Index: -1.7600
  • Cell Name: mural cell (CL0008034)
    Fold Change: -0.0837
    Cell Significance Index: -1.0200
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: -0.0842
    Cell Significance Index: -0.8000
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.0851
    Cell Significance Index: -1.1100
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: -0.0862
    Cell Significance Index: -1.1100
  • Cell Name: fibroblast (CL0000057)
    Fold Change: -0.0884
    Cell Significance Index: -0.8300
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: -0.0913
    Cell Significance Index: -1.5600
  • Cell Name: skeletal muscle satellite cell (CL0000594)
    Fold Change: -0.0929
    Cell Significance Index: -0.9800
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: -0.1023
    Cell Significance Index: -0.9900
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: -0.1030
    Cell Significance Index: -1.0400
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: -0.1047
    Cell Significance Index: -1.3500
  • Cell Name: B cell (CL0000236)
    Fold Change: -0.1054
    Cell Significance Index: -1.2500
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: -0.1063
    Cell Significance Index: -1.3900
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: -0.1164
    Cell Significance Index: -1.1300
  • Cell Name: vascular associated smooth muscle cell (CL0000359)
    Fold Change: -0.1173
    Cell Significance Index: -1.2500
  • Cell Name: pericyte (CL0000669)
    Fold Change: -0.1201
    Cell Significance Index: -1.4400
  • Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell (CL0000895)
    Fold Change: -0.1217
    Cell Significance Index: -1.0500
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: -0.1218
    Cell Significance Index: -1.3300
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: -0.1242
    Cell Significance Index: -1.2600
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: -0.1245
    Cell Significance Index: -1.2500
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: -0.1247
    Cell Significance Index: -1.1300
  • Cell Name: T follicular helper cell (CL0002038)
    Fold Change: -0.1270
    Cell Significance Index: -1.3500
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: -0.1297
    Cell Significance Index: -1.5300
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: -0.1318
    Cell Significance Index: -1.8100
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.1338
    Cell Significance Index: -2.2700
  • Cell Name: memory B cell (CL0000787)
    Fold Change: -0.1401
    Cell Significance Index: -1.4900
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: -0.1428
    Cell Significance Index: -1.2100
  • Cell Name: naive regulatory T cell (CL0002677)
    Fold Change: -0.1453
    Cell Significance Index: -1.3100
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: -0.1454
    Cell Significance Index: -1.8400
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.1477
    Cell Significance Index: -1.6900
  • Cell Name: acinar cell (CL0000622)
    Fold Change: -0.1517
    Cell Significance Index: -1.9100
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: -0.1520
    Cell Significance Index: -1.6900
  • Cell Name: macrophage (CL0000235)
    Fold Change: -0.1548
    Cell Significance Index: -1.5800
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.1561
    Cell Significance Index: -1.8400
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.1570
    Cell Significance Index: -1.9300
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.1601
    Cell Significance Index: -2.0200
  • Cell Name: mature T cell (CL0002419)
    Fold Change: -0.1614
    Cell Significance Index: -1.1600
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: -0.1631
    Cell Significance Index: -1.2600
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.1686
    Cell Significance Index: -2.2400
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: -0.1686
    Cell Significance Index: -1.9000
  • Cell Name: monocyte (CL0000576)
    Fold Change: -0.1712
    Cell Significance Index: -1.9700
  • Cell Name: malignant cell (CL0001064)
    Fold Change: -0.1718
    Cell Significance Index: -0.9200
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.1720
    Cell Significance Index: -2.0500
  • Cell Name: amacrine cell (CL0000561)
    Fold Change: -0.1725
    Cell Significance Index: -2.1600
  • Cell Name: retina horizontal cell (CL0000745)
    Fold Change: -0.1729
    Cell Significance Index: -2.1700
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.1748
    Cell Significance Index: -2.0900
  • Cell Name: stromal cell (CL0000499)
    Fold Change: -0.1752
    Cell Significance Index: -1.7900
  • Cell Name: myofibroblast cell (CL0000186)
    Fold Change: -0.1775
    Cell Significance Index: -1.8600
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: -0.1778
    Cell Significance Index: -1.8400
  • Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
    Fold Change: -0.1785
    Cell Significance Index: -1.6700
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: -0.1804
    Cell Significance Index: -1.6800
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -0.1811
    Cell Significance Index: -2.2000
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: -0.1850
    Cell Significance Index: -2.1500
  • Cell Name: CD8-positive, alpha-beta thymocyte (CL0000811)
    Fold Change: -0.1861
    Cell Significance Index: -1.7200
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: -0.1868
    Cell Significance Index: -2.1100
  • Cell Name: capillary endothelial cell (CL0002144)
    Fold Change: -0.1882
    Cell Significance Index: -2.1400
  • Cell Name: granule cell (CL0000120)
    Fold Change: -0.1906
    Cell Significance Index: -2.1700
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: -0.1911
    Cell Significance Index: -2.1700
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.1948
    Cell Significance Index: -2.3000
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: -0.1956
    Cell Significance Index: -2.1900
  • Cell Name: club cell (CL0000158)
    Fold Change: -0.2028
    Cell Significance Index: -2.2100
  • Cell Name: neuronal brush cell (CL0000555)
    Fold Change: -0.2055
    Cell Significance Index: -2.2300
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: -0.2086
    Cell Significance Index: -2.2200
  • Cell Name: glial cell (CL0000125)
    Fold Change: -0.2099
    Cell Significance Index: -2.3000
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.2099
    Cell Significance Index: -2.2500
  • Cell Name: naive B cell (CL0000788)
    Fold Change: -0.2110
    Cell Significance Index: -2.2200
  • Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
    Fold Change: -0.2236
    Cell Significance Index: -2.1200
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.2342
    Cell Significance Index: -2.2200
  • Cell Name: OFF-bipolar cell (CL0000750)
    Fold Change: -0.2424
    Cell Significance Index: -2.1400
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.2629
    Cell Significance Index: -2.1700
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: -0.3069
    Cell Significance Index: -1.9300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Pseudogenization:** RPSAP13 is a pseudogenized gene, meaning it has undergone mutations that render it non-functional. This pseudogenization is a common mechanism for the inactivation of genes in the human genome. 2. **Significant expression:** Despite its pseudogenized state, RPSAP13 is significantly expressed in various cell types, including immune cells and cancer cells. 3. **Cell type specificity:** RPSAP13 expression is specific to certain cell types, including astrocytes, malignant cells, stromal cells, and immune cells such as plasma cells, memory B cells, and B cells. 4. **Tissue specificity:** RPSAP13 expression is also tissue-specific, with significant expression in tissues such as the brain (astrocytes) and bone marrow (erythroid progenitor cells, fibroblasts, erythroblasts, and plasma cells). **Pathways and Functions:** 1. **Cell proliferation and differentiation:** RPSAP13 may play a role in regulating cell proliferation and differentiation, particularly in the context of immune cells and cancer cells. 2. **Apoptosis:** RPSAP13 may also be involved in regulating apoptosis (programmed cell death), which is a critical mechanism for eliminating damaged or infected cells. 3. **Cell survival:** RPSAP13 may contribute to cell survival by regulating the expression of genes involved in cell survival pathways. 4. **Immune cell development:** RPSAP13 may play a role in the development and maturation of immune cells, including B cells and plasma cells. **Clinical Significance:** 1. **Cancer association:** The significant expression of RPSAP13 in malignant cells suggests that it may be involved in the development and progression of cancer. 2. **Hematopoiesis:** RPSAP13 expression in erythroid progenitor cells, fibroblasts, erythroblasts, and plasma cells suggests that it may play a role in hematopoiesis, the process by which blood cells are produced. 3. **Immunological disorders:** The expression of RPSAP13 in immune cells such as plasma cells, memory B cells, and B cells suggests that it may be involved in the development of immunological disorders, such as autoimmune diseases or immunodeficiencies. 4. **Diagnostic and therapeutic potential:** Further research is needed to determine the diagnostic and therapeutic potential of RPSAP13, particularly in the context of cancer and hematological disorders. In conclusion, RPSAP13 is a gene of interest that warrants further investigation due to its significant expression in various cell types and its potential involvement in cell proliferation, differentiation, apoptosis, and cell survival. Its clinical significance in the context of cancer, hematopoiesis, and immunological disorders makes it a promising target for future research and potential therapeutic applications.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.