Details for: SNORD20

Gene ID: 6082

Symbol: SNORD20

Ensembl ID: ENSG00000207280

Description: small nucleolar RNA, C/D box 20

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.7220
    Cell Significance Index: 9.8500
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: 0.5138
    Cell Significance Index: 3.0500
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.3922
    Cell Significance Index: 4.0600
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: 0.0323
    Cell Significance Index: 0.3900
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.0247
    Cell Significance Index: 0.3500
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 0.0040
    Cell Significance Index: 0.1000
  • Cell Name: basal cell (CL0000646)
    Fold Change: 0.0008
    Cell Significance Index: 0.0100
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: -0.0008
    Cell Significance Index: -0.0100
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0012
    Cell Significance Index: -0.0200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0017
    Cell Significance Index: -0.4800
  • Cell Name: acinar cell (CL0000622)
    Fold Change: -0.0111
    Cell Significance Index: -0.1400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0155
    Cell Significance Index: -0.7200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0187
    Cell Significance Index: -0.9700
  • Cell Name: stem cell (CL0000034)
    Fold Change: -0.0221
    Cell Significance Index: -0.1600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0230
    Cell Significance Index: -1.0400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0321
    Cell Significance Index: -1.6700
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: -0.0371
    Cell Significance Index: -0.4700
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: -0.0488
    Cell Significance Index: -0.6700
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.0662
    Cell Significance Index: -0.8800
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0726
    Cell Significance Index: -1.9800
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0763
    Cell Significance Index: -1.6700
  • Cell Name: plasma cell (CL0000786)
    Fold Change: -0.0810
    Cell Significance Index: -0.9100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0817
    Cell Significance Index: -1.7700
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: -0.0826
    Cell Significance Index: -0.9600
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: -0.0828
    Cell Significance Index: -0.8400
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: -0.0851
    Cell Significance Index: -0.8500
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.0858
    Cell Significance Index: -1.1200
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: -0.0858
    Cell Significance Index: -0.8300
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: -0.0887
    Cell Significance Index: -1.0300
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.0973
    Cell Significance Index: -1.4600
  • Cell Name: glial cell (CL0000125)
    Fold Change: -0.0986
    Cell Significance Index: -1.0800
  • Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
    Fold Change: -0.0994
    Cell Significance Index: -1.0300
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.1002
    Cell Significance Index: -1.9600
  • Cell Name: serous secreting cell (CL0000313)
    Fold Change: -0.1012
    Cell Significance Index: -0.8900
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: -0.1015
    Cell Significance Index: -0.9500
  • Cell Name: vein endothelial cell (CL0002543)
    Fold Change: -0.1030
    Cell Significance Index: -1.1200
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.1039
    Cell Significance Index: -0.9900
  • Cell Name: naive B cell (CL0000788)
    Fold Change: -0.1066
    Cell Significance Index: -1.1200
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: -0.1081
    Cell Significance Index: -0.9100
  • Cell Name: brain vascular cell (CL4023072)
    Fold Change: -0.1085
    Cell Significance Index: -1.2400
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: -0.1088
    Cell Significance Index: -1.8600
  • Cell Name: club cell (CL0000158)
    Fold Change: -0.1096
    Cell Significance Index: -1.1900
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: -0.1111
    Cell Significance Index: -1.1600
  • Cell Name: medium spiny neuron (CL1001474)
    Fold Change: -0.1163
    Cell Significance Index: -1.5700
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: -0.1208
    Cell Significance Index: -1.1100
  • Cell Name: mast cell (CL0000097)
    Fold Change: -0.1239
    Cell Significance Index: -1.6300
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: -0.1264
    Cell Significance Index: -1.6500
  • Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
    Fold Change: -0.1278
    Cell Significance Index: -1.2100
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.1318
    Cell Significance Index: -1.3900
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.1330
    Cell Significance Index: -1.5900
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.1339
    Cell Significance Index: -1.6900
  • Cell Name: respiratory basal cell (CL0002633)
    Fold Change: -0.1358
    Cell Significance Index: -1.3400
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.1378
    Cell Significance Index: -1.6200
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.1381
    Cell Significance Index: -1.5800
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: -0.1395
    Cell Significance Index: -1.3600
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: -0.1417
    Cell Significance Index: -1.6700
  • Cell Name: B cell (CL0000236)
    Fold Change: -0.1481
    Cell Significance Index: -1.7500
  • Cell Name: amacrine cell (CL0000561)
    Fold Change: -0.1493
    Cell Significance Index: -1.8700
  • Cell Name: endothelial cell of artery (CL1000413)
    Fold Change: -0.1499
    Cell Significance Index: -1.5800
  • Cell Name: pulmonary alveolar type 1 cell (CL0002062)
    Fold Change: -0.1503
    Cell Significance Index: -1.6500
  • Cell Name: memory B cell (CL0000787)
    Fold Change: -0.1513
    Cell Significance Index: -1.6100
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.1516
    Cell Significance Index: -1.6300
  • Cell Name: stromal cell (CL0000499)
    Fold Change: -0.1517
    Cell Significance Index: -1.5500
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.1522
    Cell Significance Index: -1.9900
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.1528
    Cell Significance Index: -1.6700
  • Cell Name: non-classical monocyte (CL0000875)
    Fold Change: -0.1533
    Cell Significance Index: -1.7000
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.1577
    Cell Significance Index: -1.8800
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.1603
    Cell Significance Index: -1.9700
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.1626
    Cell Significance Index: -1.9200
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: -0.1627
    Cell Significance Index: -1.6600
  • Cell Name: neutrophil (CL0000775)
    Fold Change: -0.1641
    Cell Significance Index: -2.0500
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -0.1642
    Cell Significance Index: -1.9900
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: -0.1643
    Cell Significance Index: -1.8200
  • Cell Name: monocyte (CL0000576)
    Fold Change: -0.1651
    Cell Significance Index: -1.9000
  • Cell Name: fibroblast (CL0000057)
    Fold Change: -0.1651
    Cell Significance Index: -1.5500
  • Cell Name: macrophage (CL0000235)
    Fold Change: -0.1704
    Cell Significance Index: -1.7400
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: -0.1713
    Cell Significance Index: -1.9300
  • Cell Name: pulmonary alveolar type 2 cell (CL0002063)
    Fold Change: -0.1789
    Cell Significance Index: -1.4800
  • Cell Name: mesothelial cell (CL0000077)
    Fold Change: -0.1790
    Cell Significance Index: -2.1800
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: -0.1833
    Cell Significance Index: -1.8600
  • Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
    Fold Change: -0.1860
    Cell Significance Index: -1.7400
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: -0.1870
    Cell Significance Index: -1.9900
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: -0.1880
    Cell Significance Index: -1.8600
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: -0.1907
    Cell Significance Index: -1.6800
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: -0.1935
    Cell Significance Index: -1.8600
  • Cell Name: naive T cell (CL0000898)
    Fold Change: -0.2081
    Cell Significance Index: -1.8900
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: -0.2154
    Cell Significance Index: -2.2900
  • Cell Name: class switched memory B cell (CL0000972)
    Fold Change: -0.2164
    Cell Significance Index: -1.9300
  • Cell Name: cerebellar neuron (CL1001611)
    Fold Change: -0.2336
    Cell Significance Index: -1.6200
  • Cell Name: IgG plasmablast (CL0000982)
    Fold Change: -0.2374
    Cell Significance Index: -1.9600
  • Cell Name: IgA plasmablast (CL0000984)
    Fold Change: -0.2439
    Cell Significance Index: -1.9600
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: -0.2587
    Cell Significance Index: -1.9900
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: -0.2682
    Cell Significance Index: -1.6900
  • Cell Name: enterocyte (CL0000584)
    Fold Change: -0.2740
    Cell Significance Index: -1.7000
  • Cell Name: basket cell (CL0000118)
    Fold Change: -0.3400
    Cell Significance Index: -1.6400
  • Cell Name: ventricular cardiac muscle cell (CL2000046)
    Fold Change: -0.4775
    Cell Significance Index: -2.1100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** SNORD20, like other snoRNAs, is a small, non-coding RNA molecule that plays a crucial role in RNA processing and modification. The C/D box motif is a hallmark of snoRNAs, which are involved in the catalysis of modifications to ribosomal RNA (rRNA) and other RNAs. SNORD20 is specifically expressed in cells that are involved in various physiological processes, including cell growth, differentiation, and survival. Its expression in cardiac tissue and neuronal cells suggests a potential role in maintaining cardiovascular and neural function. **Pathways and Functions:** The expression of SNORD20 in different cell types suggests that it is involved in various cellular processes. Some potential pathways and functions of SNORD20 include: 1. **RNA Processing:** SNORD20 is involved in the modification of rRNA, which is essential for ribosome biogenesis and function. This process is critical for protein synthesis and cell growth. 2. **Cell Signaling:** SNORD20 may play a role in cell signaling pathways, particularly those involved in cardiovascular and neural function. Its expression in cardiac endothelial cells and smooth muscle myoblasts suggests a potential role in regulating blood pressure and vascular tone. 3. **Stem Cell Maintenance:** SNORD20 may be involved in the maintenance of stem cells, particularly those involved in the development of the cardiovascular and nervous systems. **Clinical Significance:** The clinical significance of SNORD20 is an area of active research. Studies have shown that alterations in SNORD20 expression are associated with various diseases, including: 1. **Cardiovascular Disease:** SNORD20 expression is reduced in patients with cardiovascular disease, suggesting a potential role in the development of this condition. 2. **Neurodegenerative Disorders:** SNORD20 expression is altered in patients with neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease, suggesting a potential role in the pathogenesis of these conditions. 3. **Cancer:** SNORD20 expression is altered in various types of cancer, suggesting a potential role in tumorigenesis and cancer progression. In conclusion, SNORD20 is a small nucleolar RNA with multifaceted functions in cell regulation. Its expression in various cell types and involvement in RNA processing, cell signaling, and stem cell maintenance suggest a potential role in maintaining cardiovascular and neural function. Further research is needed to fully elucidate the clinical significance of SNORD20 and its implications in human health.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.