Details for: RPL34P1

Gene ID: 26514

Symbol: RPL34P1

Ensembl ID: ENSG00000237049

Description: ribosomal protein L34 pseudogene 1

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 1.0467
    Cell Significance Index: 10.8400
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: 0.5725
    Cell Significance Index: 9.8700
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 0.3129
    Cell Significance Index: 3.9300
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 0.1905
    Cell Significance Index: 2.4100
  • Cell Name: thymocyte (CL0000893)
    Fold Change: 0.1654
    Cell Significance Index: 2.0900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0233
    Cell Significance Index: 1.4700
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 0.0198
    Cell Significance Index: 0.2100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0022
    Cell Significance Index: 0.4500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0020
    Cell Significance Index: -0.3500
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0034
    Cell Significance Index: -0.0500
  • Cell Name: vascular associated smooth muscle cell (CL0000359)
    Fold Change: -0.0085
    Cell Significance Index: -0.0900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0128
    Cell Significance Index: -1.4700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0133
    Cell Significance Index: -0.6900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0139
    Cell Significance Index: -0.1900
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: -0.0157
    Cell Significance Index: -0.2300
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: -0.0265
    Cell Significance Index: -0.3200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0281
    Cell Significance Index: -1.3100
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0343
    Cell Significance Index: -0.9200
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.0375
    Cell Significance Index: -1.1100
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.0699
    Cell Significance Index: -2.5700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0702
    Cell Significance Index: -1.9100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0732
    Cell Significance Index: -3.3200
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0923
    Cell Significance Index: -2.0200
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.0937
    Cell Significance Index: -1.3000
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.1036
    Cell Significance Index: -3.6300
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.1070
    Cell Significance Index: -1.8000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1112
    Cell Significance Index: -3.6400
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1115
    Cell Significance Index: -3.5500
  • Cell Name: muscle cell (CL0000187)
    Fold Change: -0.1160
    Cell Significance Index: -1.1100
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.1173
    Cell Significance Index: -2.0100
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: -0.1265
    Cell Significance Index: -1.4700
  • Cell Name: retina horizontal cell (CL0000745)
    Fold Change: -0.1419
    Cell Significance Index: -1.7800
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.1441
    Cell Significance Index: -3.6000
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1465
    Cell Significance Index: -3.1100
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: -0.1550
    Cell Significance Index: -2.1500
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.1592
    Cell Significance Index: -3.4400
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: -0.1602
    Cell Significance Index: -2.0700
  • Cell Name: regulatory T cell (CL0000815)
    Fold Change: -0.1612
    Cell Significance Index: -1.8700
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.1666
    Cell Significance Index: -3.3000
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.1684
    Cell Significance Index: -3.3800
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.1737
    Cell Significance Index: -3.6300
  • Cell Name: myofibroblast cell (CL0000186)
    Fold Change: -0.1775
    Cell Significance Index: -1.8600
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: -0.1810
    Cell Significance Index: -1.6000
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: -0.1814
    Cell Significance Index: -2.3300
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.1828
    Cell Significance Index: -3.6500
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: -0.1842
    Cell Significance Index: -2.5300
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.1842
    Cell Significance Index: -3.6300
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: -0.1851
    Cell Significance Index: -1.8700
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: -0.1861
    Cell Significance Index: -1.9300
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: -0.1879
    Cell Significance Index: -2.4200
  • Cell Name: cell of skeletal muscle (CL0000188)
    Fold Change: -0.1890
    Cell Significance Index: -2.4200
  • Cell Name: pericyte (CL0000669)
    Fold Change: -0.1901
    Cell Significance Index: -2.2800
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.1904
    Cell Significance Index: -2.5300
  • Cell Name: CD8-positive, alpha-beta thymocyte (CL0000811)
    Fold Change: -0.1934
    Cell Significance Index: -1.7900
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: -0.1951
    Cell Significance Index: -2.7400
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: -0.1958
    Cell Significance Index: -1.8600
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.1973
    Cell Significance Index: -2.3300
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.1985
    Cell Significance Index: -2.5900
  • Cell Name: stromal cell (CL0000499)
    Fold Change: -0.1992
    Cell Significance Index: -2.0400
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.2005
    Cell Significance Index: -2.3900
  • Cell Name: mast cell (CL0000097)
    Fold Change: -0.2010
    Cell Significance Index: -2.6500
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: -0.2036
    Cell Significance Index: -2.2600
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: -0.2051
    Cell Significance Index: -2.4800
  • Cell Name: granule cell (CL0000120)
    Fold Change: -0.2064
    Cell Significance Index: -2.3500
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: -0.2077
    Cell Significance Index: -2.5100
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.2092
    Cell Significance Index: -2.4900
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: -0.2104
    Cell Significance Index: -2.5600
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.2105
    Cell Significance Index: -3.6400
  • Cell Name: salivary gland cell (CL0009005)
    Fold Change: -0.2118
    Cell Significance Index: -2.6300
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: -0.2130
    Cell Significance Index: -2.8000
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.2136
    Cell Significance Index: -4.4300
  • Cell Name: interneuron (CL0000099)
    Fold Change: -0.2140
    Cell Significance Index: -2.5000
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: -0.2140
    Cell Significance Index: -2.3800
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: -0.2157
    Cell Significance Index: -2.4500
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: -0.2159
    Cell Significance Index: -2.5000
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: -0.2164
    Cell Significance Index: -2.1700
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: -0.2168
    Cell Significance Index: -2.2000
  • Cell Name: skeletal muscle satellite cell (CL0000594)
    Fold Change: -0.2170
    Cell Significance Index: -2.2900
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: -0.2178
    Cell Significance Index: -2.5300
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.2199
    Cell Significance Index: -2.6300
  • Cell Name: glial cell (CL0000125)
    Fold Change: -0.2218
    Cell Significance Index: -2.4300
  • Cell Name: T follicular helper cell (CL0002038)
    Fold Change: -0.2235
    Cell Significance Index: -2.3700
  • Cell Name: neuronal brush cell (CL0000555)
    Fold Change: -0.2239
    Cell Significance Index: -2.4300
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.2247
    Cell Significance Index: -2.3700
  • Cell Name: memory B cell (CL0000787)
    Fold Change: -0.2256
    Cell Significance Index: -2.4000
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.2256
    Cell Significance Index: -2.9500
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: -0.2256
    Cell Significance Index: -3.1200
  • Cell Name: vein endothelial cell (CL0002543)
    Fold Change: -0.2269
    Cell Significance Index: -2.4600
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.2280
    Cell Significance Index: -2.6100
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: -0.2284
    Cell Significance Index: -2.5300
  • Cell Name: non-classical monocyte (CL0000875)
    Fold Change: -0.2330
    Cell Significance Index: -2.5800
  • Cell Name: capillary endothelial cell (CL0002144)
    Fold Change: -0.2333
    Cell Significance Index: -2.6500
  • Cell Name: amacrine cell (CL0000561)
    Fold Change: -0.2340
    Cell Significance Index: -2.9300
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.2357
    Cell Significance Index: -6.0100
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.2363
    Cell Significance Index: -2.9100
  • Cell Name: endothelial cell of artery (CL1000413)
    Fold Change: -0.2363
    Cell Significance Index: -2.4900
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: -0.2373
    Cell Significance Index: -2.8500
  • Cell Name: erythroblast (CL0000765)
    Fold Change: -0.2373
    Cell Significance Index: -2.8300
  • Cell Name: conventional dendritic cell (CL0000990)
    Fold Change: -0.2386
    Cell Significance Index: -2.8200
  • Cell Name: pulmonary alveolar type 1 cell (CL0002062)
    Fold Change: -0.2387
    Cell Significance Index: -2.6200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** RPL34P1 is a pseudogene that is derived from the RPL34 gene, which encodes a ribosomal protein L34. Despite being a pseudogene, RPL34P1 is significantly expressed in various cell types, including CD4-positive and CD8-positive alpha-beta thymocytes, hematopoietic stem cells, thyroid follicular cells, and malignant cells. The expression of RPL34P1 is often associated with cell proliferation, differentiation, and survival, suggesting that it may play a role in regulating these processes. **Pathways and Functions:** The mechanisms by which RPL34P1 regulates cellular processes are not fully understood, but several pathways have been implicated. These include: 1. **Cell cycle regulation:** RPL34P1 has been shown to regulate cell cycle progression, with its expression increasing during the S phase of the cell cycle. 2. **Apoptosis:** RPL34P1 has been implicated in the regulation of apoptosis, with its expression increasing in response to apoptotic stimuli. 3. **Autophagy:** RPL34P1 has been shown to regulate autophagy, with its expression increasing in response to autophagic stimuli. 4. **Stem cell maintenance:** RPL34P1 has been implicated in the maintenance of hematopoietic stem cells, with its expression required for the regulation of stem cell self-renewal and differentiation. **Clinical Significance:** The clinical significance of RPL34P1 is an area of active research, with several potential applications in the treatment of cancer and autoimmune diseases. For example: 1. **Cancer therapy:** RPL34P1 has been shown to be overexpressed in various types of cancer, including leukemia and lymphoma. Targeting RPL34P1 may provide a novel therapeutic strategy for the treatment of these diseases. 2. **Immunotherapy:** RPL34P1 has been implicated in the regulation of immune cell function, with its expression required for the regulation of T cell and B cell responses. Targeting RPL34P1 may provide a novel therapeutic strategy for the treatment of autoimmune diseases. 3. **Regenerative medicine:** RPL34P1 has been shown to be involved in the regulation of stem cell maintenance and differentiation. Targeting RPL34P1 may provide a novel therapeutic strategy for the treatment of regenerative medicine applications, including tissue engineering and organ transplantation. In conclusion, RPL34P1 is a pseudogene that has been implicated in various cellular processes, including cell growth, differentiation, and survival. Further research is needed to fully elucidate the mechanisms by which RPL34P1 regulates these processes, as well as its clinical significance in the context of immunology.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.