Details for: IGLV5 37

Gene ID: 28783

Symbol: IGLV5 37

Ensembl ID: ENSG00000211654

Description: immunoglobulin lambda variable 5-37

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.0165
    Cell Significance Index: 0.2400
  • Cell Name: P/D1 enteroendocrine cell (CL0002268)
    Fold Change: 0.0158
    Cell Significance Index: 0.1800
  • Cell Name: neuron (CL0000540)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0054
    Cell Significance Index: -1.0700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0054
    Cell Significance Index: -1.0800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0073
    Cell Significance Index: -0.3400
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0118
    Cell Significance Index: -0.3000
  • Cell Name: peptic cell (CL0000155)
    Fold Change: -0.0151
    Cell Significance Index: -0.1300
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: -0.0178
    Cell Significance Index: -0.2100
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.0244
    Cell Significance Index: -0.2900
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.0268
    Cell Significance Index: -0.6500
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: -0.0270
    Cell Significance Index: -0.3500
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.0302
    Cell Significance Index: -0.5900
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.0325
    Cell Significance Index: -0.6000
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: -0.0345
    Cell Significance Index: -0.4700
  • Cell Name: naive B cell (CL0000788)
    Fold Change: -0.0351
    Cell Significance Index: -0.3700
  • Cell Name: plasma cell (CL0000786)
    Fold Change: -0.0367
    Cell Significance Index: -0.4100
  • Cell Name: class switched memory B cell (CL0000972)
    Fold Change: -0.0387
    Cell Significance Index: -0.3500
  • Cell Name: neutrophil (CL0000775)
    Fold Change: -0.0392
    Cell Significance Index: -0.4900
  • Cell Name: stromal cell (CL0000499)
    Fold Change: -0.0431
    Cell Significance Index: -0.4400
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: -0.0444
    Cell Significance Index: -0.5800
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: -0.0465
    Cell Significance Index: -0.4500
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: -0.0474
    Cell Significance Index: -0.8100
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: -0.0484
    Cell Significance Index: -0.5200
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: -0.0495
    Cell Significance Index: -0.6500
  • Cell Name: memory B cell (CL0000787)
    Fold Change: -0.0517
    Cell Significance Index: -0.5500
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: -0.0521
    Cell Significance Index: -0.6500
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: -0.0522
    Cell Significance Index: -0.6700
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: -0.0524
    Cell Significance Index: -0.5800
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: -0.0524
    Cell Significance Index: -0.5900
  • Cell Name: conventional dendritic cell (CL0000990)
    Fold Change: -0.0533
    Cell Significance Index: -0.6300
  • Cell Name: pericyte (CL0000669)
    Fold Change: -0.0534
    Cell Significance Index: -0.6400
  • Cell Name: IgA plasma cell (CL0000987)
    Fold Change: -0.0541
    Cell Significance Index: -0.3600
  • Cell Name: B cell (CL0000236)
    Fold Change: -0.0542
    Cell Significance Index: -0.6400
  • Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
    Fold Change: -0.0547
    Cell Significance Index: -0.5900
  • Cell Name: IgA plasmablast (CL0000984)
    Fold Change: -0.0547
    Cell Significance Index: -0.4400
  • Cell Name: retina horizontal cell (CL0000745)
    Fold Change: -0.0550
    Cell Significance Index: -0.6900
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.0559
    Cell Significance Index: -0.5900
  • Cell Name: non-classical monocyte (CL0000875)
    Fold Change: -0.0560
    Cell Significance Index: -0.6200
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.0561
    Cell Significance Index: -0.6900
  • Cell Name: mucosal invariant T cell (CL0000940)
    Fold Change: -0.0565
    Cell Significance Index: -0.6500
  • Cell Name: regulatory T cell (CL0000815)
    Fold Change: -0.0569
    Cell Significance Index: -0.6600
  • Cell Name: monocyte (CL0000576)
    Fold Change: -0.0574
    Cell Significance Index: -0.6600
  • Cell Name: fibroblast (CL0000057)
    Fold Change: -0.0575
    Cell Significance Index: -0.5400
  • Cell Name: plasmablast (CL0000980)
    Fold Change: -0.0582
    Cell Significance Index: -0.5400
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: -0.0583
    Cell Significance Index: -0.5600
  • Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
    Fold Change: -0.0588
    Cell Significance Index: -0.5500
  • Cell Name: promonocyte (CL0000559)
    Fold Change: -0.0590
    Cell Significance Index: -0.6300
  • Cell Name: gamma-delta T cell (CL0000798)
    Fold Change: -0.0591
    Cell Significance Index: -0.5900
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.0591
    Cell Significance Index: -0.7900
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.0593
    Cell Significance Index: -0.7000
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.0596
    Cell Significance Index: -0.7100
  • Cell Name: T follicular helper cell (CL0002038)
    Fold Change: -0.0604
    Cell Significance Index: -0.6400
  • Cell Name: vascular associated smooth muscle cell (CL0000359)
    Fold Change: -0.0604
    Cell Significance Index: -0.6400
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: -0.0611
    Cell Significance Index: -0.7100
  • Cell Name: platelet (CL0000233)
    Fold Change: -0.0622
    Cell Significance Index: -0.6400
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: -0.0626
    Cell Significance Index: -0.6100
  • Cell Name: vein endothelial cell (CL0002543)
    Fold Change: -0.0627
    Cell Significance Index: -0.6800
  • Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell (CL0000895)
    Fold Change: -0.0637
    Cell Significance Index: -0.5500
  • Cell Name: CD16-negative, CD56-bright natural killer cell, human (CL0000938)
    Fold Change: -0.0637
    Cell Significance Index: -0.6600
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: -0.0639
    Cell Significance Index: -0.6000
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: -0.0641
    Cell Significance Index: -0.6500
  • Cell Name: blood cell (CL0000081)
    Fold Change: -0.0645
    Cell Significance Index: -0.5500
  • Cell Name: immature B cell (CL0000816)
    Fold Change: -0.0645
    Cell Significance Index: -0.6100
  • Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
    Fold Change: -0.0645
    Cell Significance Index: -0.6500
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: -0.0645
    Cell Significance Index: -0.6200
  • Cell Name: mast cell (CL0000097)
    Fold Change: -0.0647
    Cell Significance Index: -0.8500
  • Cell Name: IgG plasma cell (CL0000985)
    Fold Change: -0.0667
    Cell Significance Index: -0.6100
  • Cell Name: effector memory CD4-positive, alpha-beta T cell (CL0000905)
    Fold Change: -0.0670
    Cell Significance Index: -0.6200
  • Cell Name: dendritic cell, human (CL0001056)
    Fold Change: -0.0672
    Cell Significance Index: -0.6200
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: -0.0672
    Cell Significance Index: -0.7700
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: -0.0676
    Cell Significance Index: -0.6100
  • Cell Name: central memory CD4-positive, alpha-beta T cell (CL0000904)
    Fold Change: -0.0680
    Cell Significance Index: -0.6000
  • Cell Name: transitional stage B cell (CL0000818)
    Fold Change: -0.0683
    Cell Significance Index: -0.6000
  • Cell Name: CD16-positive, CD56-dim natural killer cell, human (CL0000939)
    Fold Change: -0.0685
    Cell Significance Index: -0.6100
  • Cell Name: activated CD8-positive, alpha-beta T cell (CL0000906)
    Fold Change: -0.0694
    Cell Significance Index: -0.5800
  • Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
    Fold Change: -0.0696
    Cell Significance Index: -0.6600
  • Cell Name: obsolete animal cell (CL0000548)
    Fold Change: -0.0700
    Cell Significance Index: -0.7100
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: -0.0711
    Cell Significance Index: -0.6000
  • Cell Name: memory T cell (CL0000813)
    Fold Change: -0.0712
    Cell Significance Index: -0.5900
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: -0.0713
    Cell Significance Index: -0.4600
  • Cell Name: unswitched memory B cell (CL0000970)
    Fold Change: -0.0716
    Cell Significance Index: -0.6400
  • Cell Name: B-2 B cell (CL0000822)
    Fold Change: -0.0733
    Cell Significance Index: -0.6500
  • Cell Name: small pre-B-II cell (CL0000954)
    Fold Change: -0.0734
    Cell Significance Index: -0.5900
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: -0.0742
    Cell Significance Index: -0.7700
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: -0.0752
    Cell Significance Index: -0.7600
  • Cell Name: macrophage (CL0000235)
    Fold Change: -0.0764
    Cell Significance Index: -0.7800
  • Cell Name: CD8-positive, alpha-beta cytotoxic T cell (CL0000794)
    Fold Change: -0.0766
    Cell Significance Index: -0.6200
  • Cell Name: ciliated epithelial cell (CL0000067)
    Fold Change: -0.0778
    Cell Significance Index: -0.7700
  • Cell Name: enterocyte (CL0000584)
    Fold Change: -0.0790
    Cell Significance Index: -0.4900
  • Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
    Fold Change: -0.0792
    Cell Significance Index: -0.8200
  • Cell Name: alpha-beta T cell (CL0000789)
    Fold Change: -0.0798
    Cell Significance Index: -0.6800
  • Cell Name: activated CD4-positive, alpha-beta T cell (CL0000896)
    Fold Change: -0.0800
    Cell Significance Index: -0.5500
  • Cell Name: IgM plasma cell (CL0000986)
    Fold Change: -0.0820
    Cell Significance Index: -0.6300
  • Cell Name: mature B cell (CL0000785)
    Fold Change: -0.0830
    Cell Significance Index: -0.5400
  • Cell Name: IgG plasmablast (CL0000982)
    Fold Change: -0.0830
    Cell Significance Index: -0.6900
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: -0.0830
    Cell Significance Index: -0.9100
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: -0.0840
    Cell Significance Index: -0.7400
  • Cell Name: exhausted T cell (CL0011025)
    Fold Change: -0.0859
    Cell Significance Index: -0.7000
  • Cell Name: respiratory basal cell (CL0002633)
    Fold Change: -0.0862
    Cell Significance Index: -0.8500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Immunoglobulin lambda variable gene**: IGLV5 37 is a lambda light chain variable gene, which is one of the three types of immunoglobulin lambda chains. 2. **Significant expression in immune cells**: IGLV5 37 is expressed in various immune cells, including CD4+ and CD8+ T cells, B-2 B cells, naive B cells, classical monocytes, and natural killer cells. 3. **X-chromosome location**: IGLV5 37 is located on the X chromosome, which is a critical consideration in understanding its expression and function in males, who have only one X chromosome. 4. **Adaptive immune response**: IGLV5 37 is involved in the adaptive immune response, which is a specific and targeted response to pathogens and antigens. **Pathways and Functions:** 1. **Immunoglobulin production**: IGLV5 37 is involved in the production of immunoglobulins, which are essential for recognizing and binding to specific antigens. 2. **Antigen recognition**: The IGLV5 37 gene plays a crucial role in antigen recognition, allowing immune cells to recognize and respond to specific pathogens and antigens. 3. **Adaptive immune response**: IGLV5 37 is involved in the adaptive immune response, which is a specific and targeted response to pathogens and antigens. 4. **Immune cell activation**: IGLV5 37 is expressed in activated immune cells, such as T cells and B cells, which are essential for the immune response. **Clinical Significance:** 1. **Immune-mediated diseases**: IGLV5 37 has been implicated in various immune-mediated diseases, including autoimmune disorders and immunodeficiency diseases. 2. **Cancer immunotherapy**: IGLV5 37 has been identified as a potential target for cancer immunotherapy, as it is expressed in cancer cells and can be targeted by specific antibodies. 3. **Vaccine development**: IGLV5 37 has been identified as a potential antigen for vaccine development, as it is expressed in specific immune cells and can be targeted by specific antibodies. 4. **Immunogenetic research**: IGLV5 37 has been studied extensively in the context of immunogenetics, which is the study of the genetic basis of the immune response. In conclusion, IGLV5 37 is a critical gene involved in the adaptive immune response, and its dysregulation has been implicated in various immune-mediated diseases. Further research is needed to fully understand the role of IGLV5 37 in the immune system and its potential applications in immunotherapy and vaccine development.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.