Details for: TRNG

Gene ID: 4563

Symbol: TRNG

Ensembl ID: ENSG00000210164

Description: tRNA-Gly

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: 5.4278
    Cell Significance Index: 75.0500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 3.7078
    Cell Significance Index: 233.6900
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 3.1096
    Cell Significance Index: 32.1800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 2.3765
    Cell Significance Index: 110.8100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 2.1987
    Cell Significance Index: 99.6600
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 1.8762
    Cell Significance Index: 46.8600
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 1.3181
    Cell Significance Index: 19.7500
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: 1.0519
    Cell Significance Index: 13.5900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.9114
    Cell Significance Index: 26.2600
  • Cell Name: large intestine goblet cell (CL1000320)
    Fold Change: 0.6893
    Cell Significance Index: 7.4700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.5638
    Cell Significance Index: 29.2900
  • Cell Name: adipocyte (CL0000136)
    Fold Change: 0.2881
    Cell Significance Index: 3.8400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.2822
    Cell Significance Index: 7.6800
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: 0.1116
    Cell Significance Index: 1.0800
  • Cell Name: erythroid lineage cell (CL0000764)
    Fold Change: 0.0544
    Cell Significance Index: 0.6000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.0440
    Cell Significance Index: 0.6000
  • Cell Name: vascular associated smooth muscle cell (CL0000359)
    Fold Change: 0.0414
    Cell Significance Index: 0.4400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0103
    Cell Significance Index: 1.7600
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.0025
    Cell Significance Index: 0.0300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0025
    Cell Significance Index: -1.4200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0066
    Cell Significance Index: -12.4300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0068
    Cell Significance Index: -1.9600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0146
    Cell Significance Index: -9.2600
  • Cell Name: salivary gland cell (CL0009005)
    Fold Change: -0.0177
    Cell Significance Index: -0.2200
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.0331
    Cell Significance Index: -0.6900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0444
    Cell Significance Index: -20.1700
  • Cell Name: ionocyte (CL0005006)
    Fold Change: -0.0454
    Cell Significance Index: -0.4800
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: -0.0459
    Cell Significance Index: -0.4600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0556
    Cell Significance Index: -11.1500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0574
    Cell Significance Index: -6.5800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0626
    Cell Significance Index: -2.2000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0775
    Cell Significance Index: -11.2600
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0814
    Cell Significance Index: -2.0300
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: -0.0878
    Cell Significance Index: -0.9100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0893
    Cell Significance Index: -2.8600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0932
    Cell Significance Index: -2.0200
  • Cell Name: intestinal crypt stem cell of large intestine (CL0009016)
    Fold Change: -0.0949
    Cell Significance Index: -0.8300
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: -0.1198
    Cell Significance Index: -1.3100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1202
    Cell Significance Index: -12.5200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1248
    Cell Significance Index: -7.6500
  • Cell Name: pancreatic stellate cell (CL0002410)
    Fold Change: -0.1263
    Cell Significance Index: -1.5900
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.1442
    Cell Significance Index: -5.0500
  • Cell Name: club cell (CL0000158)
    Fold Change: -0.1643
    Cell Significance Index: -1.7900
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.1859
    Cell Significance Index: -2.9500
  • Cell Name: DN4 thymocyte (CL0000808)
    Fold Change: -0.2057
    Cell Significance Index: -1.5500
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.2231
    Cell Significance Index: -6.5700
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.2249
    Cell Significance Index: -3.3200
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.2645
    Cell Significance Index: -5.3100
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.3016
    Cell Significance Index: -7.6900
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.3099
    Cell Significance Index: -9.8700
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.3281
    Cell Significance Index: -4.5500
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.3317
    Cell Significance Index: -6.8800
  • Cell Name: serous secreting cell (CL0000313)
    Fold Change: -0.3438
    Cell Significance Index: -3.0300
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.3490
    Cell Significance Index: -5.0200
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: -0.3703
    Cell Significance Index: -6.3300
  • Cell Name: fast muscle cell (CL0000190)
    Fold Change: -0.3886
    Cell Significance Index: -5.0900
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: -0.4094
    Cell Significance Index: -5.2600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.4129
    Cell Significance Index: -13.5200
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: -0.4258
    Cell Significance Index: -4.6100
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: -0.4325
    Cell Significance Index: -5.9400
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: -0.4330
    Cell Significance Index: -4.5200
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.4372
    Cell Significance Index: -5.1400
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.4653
    Cell Significance Index: -9.2000
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -0.4686
    Cell Significance Index: -5.6800
  • Cell Name: retina horizontal cell (CL0000745)
    Fold Change: -0.4710
    Cell Significance Index: -5.9100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.4780
    Cell Significance Index: -10.1800
  • Cell Name: stem cell (CL0000034)
    Fold Change: -0.4802
    Cell Significance Index: -3.4900
  • Cell Name: naive B cell (CL0000788)
    Fold Change: -0.4806
    Cell Significance Index: -5.0600
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: -0.4880
    Cell Significance Index: -5.6700
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.4895
    Cell Significance Index: -5.8400
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: -0.4898
    Cell Significance Index: -7.3300
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.4977
    Cell Significance Index: -5.2500
  • Cell Name: macrophage (CL0000235)
    Fold Change: -0.5123
    Cell Significance Index: -5.2300
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: -0.5471
    Cell Significance Index: -4.4300
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.5581
    Cell Significance Index: -6.8600
  • Cell Name: granulocyte (CL0000094)
    Fold Change: -0.5621
    Cell Significance Index: -6.7800
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.5669
    Cell Significance Index: -8.0700
  • Cell Name: neuroblast (sensu Nematoda and Protostomia) (CL0000338)
    Fold Change: -0.5687
    Cell Significance Index: -5.1700
  • Cell Name: pericyte (CL0000669)
    Fold Change: -0.5771
    Cell Significance Index: -6.9200
  • Cell Name: tracheal goblet cell (CL1000329)
    Fold Change: -0.5964
    Cell Significance Index: -4.9300
  • Cell Name: stromal cell (CL0000499)
    Fold Change: -0.6009
    Cell Significance Index: -6.1400
  • Cell Name: fibroblast (CL0000057)
    Fold Change: -0.6045
    Cell Significance Index: -5.6800
  • Cell Name: monocyte (CL0000576)
    Fold Change: -0.6096
    Cell Significance Index: -7.0200
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.6148
    Cell Significance Index: -8.0400
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.6361
    Cell Significance Index: -7.5700
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.6577
    Cell Significance Index: -12.8600
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.6686
    Cell Significance Index: -11.3600
  • Cell Name: tendon cell (CL0000388)
    Fold Change: -0.6836
    Cell Significance Index: -9.3000
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: -0.6857
    Cell Significance Index: -8.8300
  • Cell Name: myoepithelial cell (CL0000185)
    Fold Change: -0.7008
    Cell Significance Index: -7.9500
  • Cell Name: neutrophil (CL0000775)
    Fold Change: -0.7221
    Cell Significance Index: -9.0200
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: -0.7236
    Cell Significance Index: -6.3800
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.7318
    Cell Significance Index: -15.8100
  • Cell Name: intestinal crypt stem cell (CL0002250)
    Fold Change: -0.7475
    Cell Significance Index: -5.2600
  • Cell Name: myofibroblast cell (CL0000186)
    Fold Change: -0.7527
    Cell Significance Index: -7.8900
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.7607
    Cell Significance Index: -18.9700
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.7681
    Cell Significance Index: -10.0300
  • Cell Name: endothelial cell of artery (CL1000413)
    Fold Change: -0.7695
    Cell Significance Index: -8.1100
  • Cell Name: regulatory T cell (CL0000815)
    Fold Change: -0.7733
    Cell Significance Index: -8.9700
  • Cell Name: amacrine cell (CL0000561)
    Fold Change: -0.8009
    Cell Significance Index: -10.0300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **tRNA structure and function:** tRNA-Gly is a modified tRNA molecule that has been identified in various tissues and cell types. Its structure and function are distinct from those of unmodified tRNAs, and it plays a crucial role in regulating cellular processes. 2. **Expression patterns:** The expression of tRNA-Gly has been observed in a wide range of cell types, including plasma cells, goblet cells, absorptive cells, and neoplastic cells. This suggests that tRNA-Gly may play a role in regulating cell growth, differentiation, and survival. 3. **Modified nucleosides:** tRNA-Gly contains modified nucleosides, including the 2-thiouridine and 5-methylcytosine modifications. These modifications are thought to play a role in regulating the structure and function of tRNA-Gly. **Pathways and Functions:** 1. **Regulation of cell growth and differentiation:** tRNA-Gly has been implicated in regulating cell growth and differentiation in various cell types. Its expression has been observed to increase in response to growth factors and stress signals, suggesting that it plays a role in promoting cell proliferation and differentiation. 2. **Regulation of apoptosis:** tRNA-Gly has also been shown to play a role in regulating apoptosis (programmed cell death). Its expression has been observed to decrease in response to apoptotic signals, suggesting that it may play a role in promoting cell survival. 3. **Regulation of the immune response:** tRNA-Gly has been implicated in regulating the immune response, particularly in the context of autoimmune diseases. Its expression has been observed to increase in response to inflammatory signals, suggesting that it may play a role in promoting immune tolerance. **Clinical Significance:** 1. **Cancer diagnosis and prognosis:** The expression of tRNA-Gly has been observed to be altered in various types of cancer, including colon cancer, breast cancer, and lung cancer. Its expression may serve as a biomarker for cancer diagnosis and prognosis. 2. **Autoimmune diseases:** tRNA-Gly has been implicated in regulating the immune response, particularly in the context of autoimmune diseases. Its expression may serve as a target for therapeutic interventions in the treatment of autoimmune diseases. 3. **Neurological disorders:** tRNA-Gly has been implicated in regulating neuronal function and survival. Its expression has been observed to be altered in various neurological disorders, including Alzheimer's disease and Parkinson's disease. Its expression may serve as a biomarker for diagnosis and prognosis. In conclusion, the tRNA-Gly gene is a multifaceted RNA molecule that plays a crucial role in regulating cellular processes, including cell growth, differentiation, and survival. Its expression has been observed to be altered in various physiological and pathological processes, including cancer, autoimmune diseases, and neurological disorders. Further research is needed to fully understand the functions and clinical significance of tRNA-Gly.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.