Details for: RN7SL359P

Gene ID: 106479354

Symbol: RN7SL359P

Ensembl ID: ENSG00000244384

Description: RNA, 7SL, cytoplasmic 359, pseudogene

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: 2.0925
    Cell Significance Index: 19.8800
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 1.3666
    Cell Significance Index: 17.6000
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 0.6695
    Cell Significance Index: 11.2600
  • Cell Name: trophoblast giant cell (CL0002488)
    Fold Change: 0.3762
    Cell Significance Index: 2.7100
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 0.0404
    Cell Significance Index: 0.5600
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.0196
    Cell Significance Index: 0.3100
  • Cell Name: myometrial cell (CL0002366)
    Fold Change: -0.0068
    Cell Significance Index: -0.0800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0100
    Cell Significance Index: -2.8700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0220
    Cell Significance Index: -2.5200
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.0618
    Cell Significance Index: -1.8200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0672
    Cell Significance Index: -3.5000
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.0778
    Cell Significance Index: -0.8200
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: -0.0982
    Cell Significance Index: -0.9500
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: -0.1037
    Cell Significance Index: -1.4300
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.1063
    Cell Significance Index: -1.5100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1117
    Cell Significance Index: -5.2100
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.1157
    Cell Significance Index: -3.1000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.1167
    Cell Significance Index: -1.5900
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.1347
    Cell Significance Index: -2.9500
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.1391
    Cell Significance Index: -1.4400
  • Cell Name: cell of skeletal muscle (CL0000188)
    Fold Change: -0.1413
    Cell Significance Index: -1.8100
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.1431
    Cell Significance Index: -2.4700
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.1585
    Cell Significance Index: -2.6700
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.1693
    Cell Significance Index: -2.5000
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: -0.1762
    Cell Significance Index: -2.2300
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.2012
    Cell Significance Index: -2.9700
  • Cell Name: vascular associated smooth muscle cell (CL0000359)
    Fold Change: -0.2058
    Cell Significance Index: -2.1900
  • Cell Name: muscle cell (CL0000187)
    Fold Change: -0.2112
    Cell Significance Index: -2.0200
  • Cell Name: pancreatic stellate cell (CL0002410)
    Fold Change: -0.2285
    Cell Significance Index: -2.8800
  • Cell Name: acinar cell (CL0000622)
    Fold Change: -0.2293
    Cell Significance Index: -2.8800
  • Cell Name: fast muscle cell (CL0000190)
    Fold Change: -0.2373
    Cell Significance Index: -3.1100
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: -0.2429
    Cell Significance Index: -3.1200
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.2460
    Cell Significance Index: -3.2100
  • Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
    Fold Change: -0.2511
    Cell Significance Index: -2.3800
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: -0.2522
    Cell Significance Index: -2.9300
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.2526
    Cell Significance Index: -4.2900
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: -0.2527
    Cell Significance Index: -1.5700
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: -0.2529
    Cell Significance Index: -2.9400
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.2579
    Cell Significance Index: -3.1700
  • Cell Name: CD8-positive, alpha-beta thymocyte (CL0000811)
    Fold Change: -0.2595
    Cell Significance Index: -2.4000
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.2705
    Cell Significance Index: -3.2300
  • Cell Name: B cell (CL0000236)
    Fold Change: -0.2716
    Cell Significance Index: -3.2100
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: -0.2721
    Cell Significance Index: -3.0900
  • Cell Name: amacrine cell (CL0000561)
    Fold Change: -0.2755
    Cell Significance Index: -3.4500
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: -0.2756
    Cell Significance Index: -3.4400
  • Cell Name: granule cell (CL0000120)
    Fold Change: -0.2767
    Cell Significance Index: -3.1500
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.2773
    Cell Significance Index: -3.2600
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: -0.2778
    Cell Significance Index: -3.0900
  • Cell Name: pericyte (CL0000669)
    Fold Change: -0.2802
    Cell Significance Index: -3.3600
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: -0.2802
    Cell Significance Index: -2.8900
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.2810
    Cell Significance Index: -3.3600
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: -0.2833
    Cell Significance Index: -3.8900
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -0.2846
    Cell Significance Index: -3.4500
  • Cell Name: chromaffin cell (CL0000166)
    Fold Change: -0.2895
    Cell Significance Index: -3.1900
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: -0.2945
    Cell Significance Index: -3.5000
  • Cell Name: tendon cell (CL0000388)
    Fold Change: -0.2960
    Cell Significance Index: -4.0200
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.2979
    Cell Significance Index: -3.4100
  • Cell Name: stromal cell (CL0000499)
    Fold Change: -0.2985
    Cell Significance Index: -3.0500
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: -0.2986
    Cell Significance Index: -3.3200
  • Cell Name: medium spiny neuron (CL1001474)
    Fold Change: -0.3009
    Cell Significance Index: -4.0600
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: -0.3036
    Cell Significance Index: -3.1900
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: -0.3036
    Cell Significance Index: -3.1700
  • Cell Name: mucosal invariant T cell (CL0000940)
    Fold Change: -0.3041
    Cell Significance Index: -3.5000
  • Cell Name: neuronal brush cell (CL0000555)
    Fold Change: -0.3142
    Cell Significance Index: -3.4100
  • Cell Name: fibroblast (CL0000057)
    Fold Change: -0.3142
    Cell Significance Index: -2.9500
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: -0.3186
    Cell Significance Index: -3.4400
  • Cell Name: retinal pigment epithelial cell (CL0002586)
    Fold Change: -0.3198
    Cell Significance Index: -3.4400
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.3219
    Cell Significance Index: -3.8300
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: -0.3234
    Cell Significance Index: -3.2100
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.3386
    Cell Significance Index: -3.2100
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.3395
    Cell Significance Index: -3.6400
  • Cell Name: melanocyte (CL0000148)
    Fold Change: -0.3404
    Cell Significance Index: -3.1900
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: -0.3532
    Cell Significance Index: -4.0900
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: -0.3568
    Cell Significance Index: -3.2200
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.3582
    Cell Significance Index: -4.5200
  • Cell Name: brain vascular cell (CL4023072)
    Fold Change: -0.3589
    Cell Significance Index: -4.1000
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: -0.3796
    Cell Significance Index: -3.4600
  • Cell Name: kidney collecting duct intercalated cell (CL1001432)
    Fold Change: -0.3833
    Cell Significance Index: -3.6500
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: -0.3891
    Cell Significance Index: -3.7500
  • Cell Name: OFF-bipolar cell (CL0000750)
    Fold Change: -0.3894
    Cell Significance Index: -3.4300
  • Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
    Fold Change: -0.3969
    Cell Significance Index: -3.7100
  • Cell Name: blood vessel smooth muscle cell (CL0019018)
    Fold Change: -0.4046
    Cell Significance Index: -3.8200
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.4066
    Cell Significance Index: -4.8000
  • Cell Name: ionocyte (CL0005006)
    Fold Change: -0.4096
    Cell Significance Index: -4.2800
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: -0.4107
    Cell Significance Index: -3.1600
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.4158
    Cell Significance Index: -4.5300
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: -0.4186
    Cell Significance Index: -3.2000
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: -0.4211
    Cell Significance Index: -4.8900
  • Cell Name: kidney interstitial cell (CL1000500)
    Fold Change: -0.4288
    Cell Significance Index: -3.2100
  • Cell Name: macrophage (CL0000235)
    Fold Change: -0.4682
    Cell Significance Index: -4.7800
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: -0.4743
    Cell Significance Index: -4.5600
  • Cell Name: myofibroblast cell (CL0000186)
    Fold Change: -0.4961
    Cell Significance Index: -5.2000
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: -0.5088
    Cell Significance Index: -2.9300
  • Cell Name: bronchial smooth muscle cell (CL0002598)
    Fold Change: -0.5342
    Cell Significance Index: -3.5700
  • Cell Name: kidney proximal convoluted tubule epithelial cell (CL1000838)
    Fold Change: -0.5789
    Cell Significance Index: -4.8800
  • Cell Name: malignant cell (CL0001064)
    Fold Change: -0.5809
    Cell Significance Index: -3.1100
  • Cell Name: cerebellar neuron (CL1001611)
    Fold Change: -0.5897
    Cell Significance Index: -4.0900
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: -0.6121
    Cell Significance Index: -6.9000
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: -0.6414
    Cell Significance Index: -6.6400
  • Cell Name: club cell (CL0000158)
    Fold Change: -0.6668
    Cell Significance Index: -7.2700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** RN7SL359P is a pseudogene, meaning it lacks the coding capacity for a protein. Its expression is significantly elevated in numerous cell types, including: 1. Oligodendrocytes: These cells are responsible for myelination in the central nervous system, and RN7SL359P's expression in this cell type suggests a potential role in neural development or maintenance. 2. Intestinal epithelial cells: The gut-associated lymphoid tissue (GALT) plays a crucial role in immune regulation, and RN7SL359P's expression in these cells may contribute to the development of immune tolerance or homeostasis. 3. Neoplastic cells: The presence of RN7SL359P in neoplastic cells raises concerns about its potential involvement in cancer development or progression. **Pathways and Functions:** While the exact mechanisms underlying RN7SL359P's functions are unknown, several pathways are hypothesized based on its expression profile: 1. **Immunoregulation:** RN7SL359P's expression in intestinal epithelial cells and goblet cells suggests a role in regulating the immune response in the gut-associated lymphoid tissue (GALT). 2. **Cellular differentiation:** RN7SL359P's expression in oligodendrocytes and intestinal epithelial cells may contribute to the regulation of cellular differentiation processes. 3. **DNA repair:** Some pseudogenes, including RN7SL359P, have been implicated in DNA repair mechanisms. Its expression in neoplastic cells may suggest a role in cancer development or progression. **Clinical Significance:** RN7SL359P's involvement in immune regulation, cellular differentiation, and potentially DNA repair mechanisms raises several clinical implications: 1. **Immune-related disorders:** RN7SL359P's expression in intestinal epithelial cells and goblet cells may contribute to the development of immune-related disorders, such as inflammatory bowel disease (IBD). 2. **Cancer:** The presence of RN7SL359P in neoplastic cells may suggest a role in cancer development or progression, particularly in the context of immunosuppression. 3. **Neurological disorders:** RN7SL359P's expression in oligodendrocytes may contribute to the development of neurological disorders, such as multiple sclerosis. In conclusion, RN7SL359P is a pseudogene with a complex expression profile that warrants further investigation. Its involvement in immune regulation, cellular differentiation, and potentially DNA repair mechanisms raises several clinical implications, including the potential for involvement in immune-related disorders, cancer, and neurological disorders. Further research is necessary to fully elucidate the functions and clinical significance of RN7SL359P.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.