Details for: KLHL29
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 32.65rCSI 57.65%PRS 34.14
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CSI 27.26rCSI 45.76%PRS 35.14
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CSI 18.95rCSI 23.58%PRS 33.42
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CSI 18.52rCSI 21.39%PRS 45.96
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CSI 17.37rCSI 32.53%PRS 41.13
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CSI 17.35rCSI 42.17%PRS 33.92
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CSI 15.02rCSI 54.06%PRS 33.85
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CSI 14.82rCSI 24.41%PRS 57.65
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CSI 13.66rCSI 34.55%PRS 60.65
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CSI 12.9rCSI 22.31%PRS 42.41
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CSI 12.79rCSI 35.98%PRS 50.36
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CSI 12.1rCSI 37.8%PRS 36.52
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CSI 12.06rCSI 14.4%PRS 34.99
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CSI 11.77rCSI 18.94%PRS 37.28
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CSI 11.69rCSI 23.2%PRS 50.43
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CSI 11.54rCSI 14.81%PRS 49.81
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CSI 11.13rCSI 49.47%PRS 51.13
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CSI 11.06rCSI 14.26%PRS 36.2
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CSI 10.85rCSI 34.7%PRS 49.03
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CSI 9.47rCSI 32.45%PRS 42.26
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CSI 9.28rCSI 12.7%PRS 47.05
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CSI 9.07rCSI 13.41%PRS 57.5
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CSI 8.96rCSI 28.01%PRS 38.99
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CSI 8.43rCSI 9.23%PRS 55.89
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CSI 8.4rCSI 21.72%PRS 47.64
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CSI 8.32rCSI 10.68%PRS 46.24
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CSI 8.19rCSI 14.36%PRS 44.27
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CSI 7.29rCSI 16.83%PRS 42.42
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CSI 6.71rCSI 9.87%PRS 46.61
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CSI 6.64rCSI 16.23%PRS 46.83
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CSI 6.6rCSI 65.95%PRS 17.24
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CSI 6.46rCSI 24.39%PRS 41.56
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CSI 6.35rCSI 33.39%PRS 58.83
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CSI 6.3rCSI 11.11%PRS 49.69
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CSI 6.19rCSI 23.38%PRS 35.97
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CSI 6.13rCSI 16.31%PRS 43.06
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CSI 5.91rCSI 16.8%PRS 50.83
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CSI 5.9rCSI 11.98%PRS 33.12
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CSI 5.75rCSI 21.54%PRS 44.54
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CSI 5.67rCSI 41.66%PRS 39.51
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CSI 5.63rCSI 9.21%PRS 41.99
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CSI 5.54rCSI 31.3%PRS 37.89
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CSI 5.49rCSI 28.13%PRS 56.07
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CSI 5.49rCSI 8.38%PRS 52.76
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CSI 5.39rCSI 7.64%PRS 48.64
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CSI 5.35rCSI 7.16%PRS 53.2
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CSI 5.15rCSI 3.82%PRS 45.02
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CSI 5.08rCSI 6.28%PRS 48.02
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CSI 5.05rCSI 10.15%PRS 41.45
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CSI 4.82rCSI 7.66%PRS 44.67
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CSI 4.8rCSI 22.98%PRS 52.01
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CSI 4.64rCSI 3.66%PRS 39.28
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CSI 4.57rCSI 26.91%PRS 36.6
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CSI 4.57rCSI 9.91%PRS 41.43
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CSI 4.54rCSI 8.25%PRS 44.97
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CSI 4.53rCSI 9.39%PRS 49.51
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CSI 4.47rCSI 11.5%PRS 53.14
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CSI 4.32rCSI 12.51%PRS 42.57
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CSI 4.12rCSI 8.46%PRS 44.41
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CSI 4.01rCSI 9.6%PRS 40.43
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CSI 3.96rCSI 10.9%PRS 48.24
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CSI 3.87rCSI 3.61%PRS 51.87
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CSI 3.87rCSI 6.83%PRS 60.41
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CSI 3.86rCSI 5.99%PRS 60.78
-
CSI 3.84rCSI 18.4%PRS 51.33
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CSI 3.84rCSI 8.76%PRS 44.76
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CSI 3.8rCSI 32.73%PRS 39.28
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CSI 3.77rCSI 11.13%PRS 50.43
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CSI 3.4rCSI 11.05%PRS 53.49
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CSI 3.37rCSI 9%PRS 44.06
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CSI 3.33rCSI 19.21%PRS 52.66
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CSI 3.29rCSI 5.83%PRS 30.69
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CSI 3.16rCSI 4.99%PRS 53.37
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CSI 3rCSI 9.87%PRS 40.21
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CSI 2.92rCSI 13.03%PRS 37.24
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CSI 2.88rCSI 9.66%PRS 38.81
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CSI 2.83rCSI 6.24%PRS 39.36
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CSI 2.7rCSI 2.19%PRS 52.57
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CSI 2.67rCSI 4.26%PRS 56.08
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CSI 2.44rCSI 9.29%PRS 44.22
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CSI 2.42rCSI 9.75%PRS 50.52
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CSI 2.33rCSI 55.87%PRS 34.61
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CSI 2.3rCSI 55.57%PRS 35.58
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CSI 2.28rCSI 21.03%PRS 66.41
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CSI 2.03rCSI 4.88%PRS 61.02
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CSI 1.99rCSI 3.08%PRS 49.97
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CSI 1.97rCSI 3.17%PRS 42.24
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CSI 1.84rCSI 3.01%PRS 26.91
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CSI 1.7rCSI 4.42%PRS 50.74
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CSI 1.69rCSI 12.71%PRS 46.64
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CSI 1.57rCSI 3.99%PRS 41.96
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CSI 1.48rCSI 8.27%PRS 66.07
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CSI 1.26rCSI 2.78%PRS 49.76
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CSI 1.2rCSI 1.39%PRS 42.06
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CSI 1.18rCSI 9.61%PRS 45.78
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CSI 1.03rCSI 4.51%PRS 49.75
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CSI 0.94rCSI 6.64%PRS 44.3
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CSI 0.74rCSI 0.89%PRS 50.02
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CSI 0.46rCSI 9.31%PRS 43.73
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CSI 0.45rCSI 9.24%PRS 45.05
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CSI 0.4rCSI 4.1%PRS 51.9%
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CSI 0.5rCSI 9.2%PRS 45.1%
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CSI 0.5rCSI 9.3%PRS 43.7%
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CSI 0.7rCSI 0.9%PRS 50.0%
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CSI 0.9rCSI 6.6%PRS 44.3%
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CSI 1.0rCSI 4.5%PRS 49.8%
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CSI 1.2rCSI 9.6%PRS 45.8%
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CSI 1.2rCSI 1.4%PRS 42.1%
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CSI 1.3rCSI 2.8%PRS 49.8%
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CSI 1.5rCSI 8.3%PRS 66.1%
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CSI 1.6rCSI 4.0%PRS 42.0%
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CSI 1.7rCSI 12.7%PRS 46.6%
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CSI 1.7rCSI 4.4%PRS 50.7%
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CSI 1.8rCSI 3.0%PRS 26.9%
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CSI 2.0rCSI 3.2%PRS 42.2%
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CSI 2.0rCSI 3.1%PRS 50.0%
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CSI 2.0rCSI 4.9%PRS 61.0%
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CSI 2.3rCSI 21.0%PRS 66.4%
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CSI 2.3rCSI 55.6%PRS 35.6%
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CSI 2.3rCSI 55.9%PRS 34.6%
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CSI 2.4rCSI 9.8%PRS 50.5%
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CSI 2.4rCSI 9.3%PRS 44.2%
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CSI 2.7rCSI 4.3%PRS 56.1%
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CSI 2.7rCSI 2.2%PRS 52.6%
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CSI 2.8rCSI 6.2%PRS 39.4%
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CSI 2.9rCSI 9.7%PRS 38.8%
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CSI 2.9rCSI 13.0%PRS 37.2%
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CSI 3.0rCSI 9.9%PRS 40.2%
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CSI 3.2rCSI 5.0%PRS 53.4%
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CSI 3.3rCSI 5.8%PRS 30.7%
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CSI 3.3rCSI 19.2%PRS 52.7%
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CSI 3.4rCSI 9.0%PRS 44.1%
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CSI 3.4rCSI 11.1%PRS 53.5%
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CSI 3.8rCSI 11.1%PRS 50.4%
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CSI 3.8rCSI 32.7%PRS 39.3%
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CSI 3.8rCSI 8.8%PRS 44.8%
-
CSI 3.8rCSI 18.4%PRS 51.3%
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CSI 3.9rCSI 6.0%PRS 60.8%
-
CSI 3.9rCSI 6.8%PRS 60.4%
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CSI 3.9rCSI 3.6%PRS 51.9%
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CSI 4.0rCSI 10.9%PRS 48.2%
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CSI 4.0rCSI 9.6%PRS 40.4%
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CSI 4.1rCSI 8.5%PRS 44.4%
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CSI 4.3rCSI 12.5%PRS 42.6%
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CSI 4.5rCSI 11.5%PRS 53.1%
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CSI 4.5rCSI 9.4%PRS 49.5%
-
CSI 4.5rCSI 8.3%PRS 45.0%
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CSI 4.6rCSI 9.9%PRS 41.4%
-
CSI 4.6rCSI 26.9%PRS 36.6%
-
CSI 4.6rCSI 3.7%PRS 39.3%
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CSI 4.8rCSI 23.0%PRS 52.0%
-
CSI 4.8rCSI 7.7%PRS 44.7%
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CSI 5.1rCSI 10.2%PRS 41.5%
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CSI 5.1rCSI 6.3%PRS 48.0%
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CSI 5.2rCSI 3.8%PRS 45.0%
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CSI 5.4rCSI 7.2%PRS 53.2%
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CSI 5.4rCSI 7.6%PRS 48.6%
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CSI 5.5rCSI 8.4%PRS 52.8%
-
CSI 5.5rCSI 28.1%PRS 56.1%
-
CSI 5.5rCSI 31.3%PRS 37.9%
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CSI 5.6rCSI 9.2%PRS 42.0%
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CSI 5.7rCSI 41.7%PRS 39.5%
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CSI 5.8rCSI 21.5%PRS 44.5%
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CSI 5.9rCSI 12.0%PRS 33.1%
-
CSI 5.9rCSI 16.8%PRS 50.8%
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CSI 6.1rCSI 16.3%PRS 43.1%
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CSI 6.2rCSI 23.4%PRS 36.0%
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CSI 6.3rCSI 11.1%PRS 49.7%
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CSI 6.4rCSI 33.4%PRS 58.8%
-
CSI 6.5rCSI 24.4%PRS 41.6%
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CSI 6.6rCSI 66.0%PRS 17.2%
-
CSI 6.6rCSI 16.2%PRS 46.8%
-
CSI 6.7rCSI 9.9%PRS 46.6%
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CSI 7.3rCSI 16.8%PRS 42.4%
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CSI 8.2rCSI 14.4%PRS 44.3%
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CSI 8.3rCSI 10.7%PRS 46.2%
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CSI 8.4rCSI 21.7%PRS 47.6%
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CSI 8.4rCSI 9.2%PRS 55.9%
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CSI 9.0rCSI 28.0%PRS 39.0%
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CSI 9.1rCSI 13.4%PRS 57.5%
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CSI 9.3rCSI 12.7%PRS 47.1%
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CSI 9.5rCSI 32.5%PRS 42.3%
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CSI 10.9rCSI 34.7%PRS 49.0%
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CSI 11.1rCSI 14.3%PRS 36.2%
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CSI 11.1rCSI 49.5%PRS 51.1%
-
CSI 11.5rCSI 14.8%PRS 49.8%
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CSI 11.7rCSI 23.2%PRS 50.4%
-
CSI 11.8rCSI 18.9%PRS 37.3%
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CSI 12.1rCSI 14.4%PRS 35.0%
-
CSI 12.1rCSI 37.8%PRS 36.5%
-
CSI 12.8rCSI 36.0%PRS 50.4%
-
CSI 12.9rCSI 22.3%PRS 42.4%
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CSI 13.7rCSI 34.6%PRS 60.7%
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CSI 14.8rCSI 24.4%PRS 57.7%
-
CSI 15.0rCSI 54.1%PRS 33.9%
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CSI 17.4rCSI 42.2%PRS 33.9%
-
CSI 17.4rCSI 32.5%PRS 41.1%
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CSI 18.5rCSI 21.4%PRS 46.0%
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CSI 19.0rCSI 23.6%PRS 33.4%
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CSI 27.3rCSI 45.8%PRS 35.1%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Comma-separated if multiple.
Comma-separated if multiple.
Legend:
- Query Gene
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Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Disclaimer: This in-silico analysis is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.
Genular Protein ID: 2979811490
Symbol: KLH29_HUMAN
Name: Kelch-like protein 29
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 11572484
Title: Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins.
PubMed ID: 11572484
Sequence Information:
- Length: 875
- Mass: 94228
- Checksum: 9B2EBF4F5D0099DD
- Sequence:
MSRHHSRFER DYRVGWDRRE WSVNGTHGTT SICSVTSGAG GGTASSLSVR PGLLPLPVVP SRLPTPATAP APCTTGSSEA ITSLVASSAS AVTTKAPGIS KGDSQSQGLA TSIRWGQTPI NQSTPWDTDE PPSKQMRESD NPGTGPWVTT VAAGNQPTLI AHSYGVAQPP TFSPAVNVQA PVIGVTPSLP PHVGPQLPLM PGHYSLPQPP SQPLSSVVVN MPAQALYASP QPLAVSTLPG VGQVARPGPT AVGNGHMAGP LLPPPPPAQP SATLPSGAPA TNGPPTTDSA HGLQMLRTIG VGKYEFTDPG HPREMLKELN QQRRAKAFTD LKIVVEGREF EVHQNVLASC SLYFKDLIQR SVQDSGQGGR EKLELVLSNL QADVLELLLE FVYTGSLVID SANAKTLLEA ASKFQFHTFC KVCVSFLEKQ LTASNCLGVL AMAEAMQCSE LYHMAKAFAL QIFPEVAAQE EILSISKDDF IAYVSNDSLN TKAEELVYET VIKWIKKDPA TRTQYAAELL AVVRLPFIHP SYLLNVVDNE ELIKSSEACR DLVNEAKRYH MLPHARQEMQ TPRTRPRLSA GVAEVIVLVG GRQMVGMTQR SLVAVTCWNP QNNKWYPLAS LPFYDREFFS VVSAGDNIYL SGGMESGVTL ADVWCYMSLL DNWNLVSRMT VPRCRHNSLV YDGKIYTLGG LGVAGNVDHV ERYDTITNQW EAVAPLPKAV HSAAATVCGG KIYVFGGVNE AGRAAGVLQS YVPQTNTWSF IESPMIDNKY APAVTLNGFV FILGGAYARA TTIYDPEKGN IKAGPNMNHS RQFCSAVVLD GKIYATGGIV SSEGPALGNM EAYEPTTNTW TLLPHMPCPV FRHGCVVIKK YIQSG