Details for: OR1Q1

Gene ID: 158131

Symbol: OR1Q1

Ensembl ID: ENSG00000165202

Description: olfactory receptor family 1 subfamily Q member 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: adipocyte (CL0000136)
    Fold Change: 0.2607
    Cell Significance Index: 3.4800
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.0162
    Cell Significance Index: 0.2300
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0001
    Cell Significance Index: -0.0100
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0004
    Cell Significance Index: -0.0200
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.0028
    Cell Significance Index: -0.0400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0052
    Cell Significance Index: -2.8200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0053
    Cell Significance Index: -1.0700
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: -0.0060
    Cell Significance Index: -0.0900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0075
    Cell Significance Index: -2.6800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0113
    Cell Significance Index: -0.7100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0232
    Cell Significance Index: -3.1800
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0287
    Cell Significance Index: -0.9200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0346
    Cell Significance Index: -1.5700
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.0351
    Cell Significance Index: -0.7200
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0371
    Cell Significance Index: -1.3000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0376
    Cell Significance Index: -1.7600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0403
    Cell Significance Index: -1.3200
  • Cell Name: regulatory T cell (CL0000815)
    Fold Change: -0.0586
    Cell Significance Index: -0.6800
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0678
    Cell Significance Index: -1.6900
  • Cell Name: pericyte (CL0000669)
    Fold Change: -0.0817
    Cell Significance Index: -0.9800
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.0828
    Cell Significance Index: -1.6300
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0850
    Cell Significance Index: -1.6800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0889
    Cell Significance Index: -4.1800
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0914
    Cell Significance Index: -1.9400
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.0925
    Cell Significance Index: -1.8500
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0963
    Cell Significance Index: -2.0800
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.1001
    Cell Significance Index: -2.0900
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.1081
    Cell Significance Index: -2.1700
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: -0.1165
    Cell Significance Index: -1.4200
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.1175
    Cell Significance Index: -1.2800
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: -0.1205
    Cell Significance Index: -1.2500
  • Cell Name: pulmonary capillary endothelial cell (CL4028001)
    Fold Change: -0.1215
    Cell Significance Index: -1.6600
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: -0.1228
    Cell Significance Index: -1.3600
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.1229
    Cell Significance Index: -3.1300
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.1261
    Cell Significance Index: -2.1800
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.1356
    Cell Significance Index: -2.0600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.1458
    Cell Significance Index: -4.1800
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: -0.1466
    Cell Significance Index: -1.7700
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.1538
    Cell Significance Index: -1.8400
  • Cell Name: mesothelial cell (CL0000077)
    Fold Change: -0.1571
    Cell Significance Index: -1.9100
  • Cell Name: pulmonary alveolar type 1 cell (CL0002062)
    Fold Change: -0.1580
    Cell Significance Index: -1.7300
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: -0.1607
    Cell Significance Index: -1.5900
  • Cell Name: fibroblast (CL0000057)
    Fold Change: -0.1640
    Cell Significance Index: -1.5400
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.1647
    Cell Significance Index: -2.1500
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: -0.1662
    Cell Significance Index: -1.9300
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: -0.1697
    Cell Significance Index: -2.1800
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: -0.1762
    Cell Significance Index: -1.9000
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.1811
    Cell Significance Index: -3.5400
  • Cell Name: melanocyte of skin (CL1000458)
    Fold Change: -0.1812
    Cell Significance Index: -2.5400
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.1828
    Cell Significance Index: -2.3900
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.1834
    Cell Significance Index: -3.0900
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: -0.1837
    Cell Significance Index: -3.1400
  • Cell Name: suprabasal keratinocyte (CL4033013)
    Fold Change: -0.1841
    Cell Significance Index: -2.9600
  • Cell Name: T follicular helper cell (CL0002038)
    Fold Change: -0.1867
    Cell Significance Index: -1.9800
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: -0.1877
    Cell Significance Index: -3.0400
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.1882
    Cell Significance Index: -2.2400
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: -0.1922
    Cell Significance Index: -2.6400
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: -0.1978
    Cell Significance Index: -1.1700
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: -0.1985
    Cell Significance Index: -2.5200
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.2008
    Cell Significance Index: -3.4100
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.2024
    Cell Significance Index: -2.3900
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.2036
    Cell Significance Index: -2.3300
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: -0.2038
    Cell Significance Index: -2.9700
  • Cell Name: kidney collecting duct intercalated cell (CL1001432)
    Fold Change: -0.2074
    Cell Significance Index: -1.9800
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: -0.2140
    Cell Significance Index: -1.9500
  • Cell Name: conventional dendritic cell (CL0000990)
    Fold Change: -0.2183
    Cell Significance Index: -2.5800
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: -0.2186
    Cell Significance Index: -1.9700
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: -0.2219
    Cell Significance Index: -2.7000
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.2220
    Cell Significance Index: -2.6100
  • Cell Name: retina horizontal cell (CL0000745)
    Fold Change: -0.2263
    Cell Significance Index: -2.8400
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.2268
    Cell Significance Index: -1.8700
  • Cell Name: amacrine cell (CL0000561)
    Fold Change: -0.2280
    Cell Significance Index: -2.8600
  • Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell (CL0000895)
    Fold Change: -0.2295
    Cell Significance Index: -1.9800
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.2332
    Cell Significance Index: -3.3400
  • Cell Name: chondrocyte (CL0000138)
    Fold Change: -0.2360
    Cell Significance Index: -2.7200
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: -0.2390
    Cell Significance Index: -2.7000
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.2417
    Cell Significance Index: -2.7500
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: -0.2438
    Cell Significance Index: -3.2000
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.2453
    Cell Significance Index: -2.6300
  • Cell Name: cell of skeletal muscle (CL0000188)
    Fold Change: -0.2467
    Cell Significance Index: -3.1600
  • Cell Name: mononuclear phagocyte (CL0000113)
    Fold Change: -0.2479
    Cell Significance Index: -2.1000
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.2489
    Cell Significance Index: -3.0600
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -0.2521
    Cell Significance Index: -3.3600
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: -0.2577
    Cell Significance Index: -1.9700
  • Cell Name: monocyte (CL0000576)
    Fold Change: -0.2581
    Cell Significance Index: -2.9700
  • Cell Name: vascular associated smooth muscle cell (CL0000359)
    Fold Change: -0.2674
    Cell Significance Index: -2.8400
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: -0.2706
    Cell Significance Index: -2.7600
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: -0.2724
    Cell Significance Index: -3.0500
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: -0.2750
    Cell Significance Index: -3.5900
  • Cell Name: mast cell (CL0000097)
    Fold Change: -0.2812
    Cell Significance Index: -3.7000
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.2864
    Cell Significance Index: -2.7200
  • Cell Name: B cell (CL0000236)
    Fold Change: -0.2869
    Cell Significance Index: -3.3900
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: -0.2883
    Cell Significance Index: -3.3500
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.2886
    Cell Significance Index: -3.4400
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -0.2920
    Cell Significance Index: -3.5400
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: -0.2924
    Cell Significance Index: -3.6500
  • Cell Name: macrophage (CL0000235)
    Fold Change: -0.2929
    Cell Significance Index: -2.9900
  • Cell Name: plasma cell (CL0000786)
    Fold Change: -0.2945
    Cell Significance Index: -3.2900
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: -0.3017
    Cell Significance Index: -3.4000
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: -0.3044
    Cell Significance Index: -3.1400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** The OR1Q1 gene exhibits several key characteristics that underscore its importance in olfactory perception. Firstly, it belongs to the olfactory receptor family, which is a group of G protein-coupled receptors (GPCRs) that are specifically expressed in the olfactory epithelium. These receptors are responsible for detecting odorant molecules in the air and transmitting this information to the brain via electrical signals. The OR1Q1 gene is also highly expressed in various cell types, including those involved in the development and maintenance of the olfactory system. Furthermore, the OR1Q1 gene has been implicated in several signaling pathways, including G protein-coupled receptor activity and olfactory signaling pathway, which highlights its role in modulating sensory perception. **Pathways and Functions:** The OR1Q1 gene is involved in several key pathways that are essential for olfactory perception. Firstly, it is part of the detection of chemical stimulus involved in sensory perception of smell pathway, which is a complex process that involves the binding of odorant molecules to olfactory receptors. This binding event triggers a signaling cascade that ultimately leads to the transmission of electrical signals to the brain, where they are interpreted as specific odors. The OR1Q1 gene is also involved in the expression and translocation of olfactory receptors, which is critical for the development and maintenance of the olfactory system. Additionally, the OR1Q1 gene is part of the G protein-coupled receptor activity pathway, which is a signaling pathway that is involved in modulating various cellular processes, including cell growth, differentiation, and survival. **Clinical Significance:** The OR1Q1 gene has significant implications for our understanding of olfactory disorders and diseases. Mutations in the OR1Q1 gene have been implicated in several olfactory disorders, including anosmia (the loss of the sense of smell) and hyposmia (reduced sensitivity to odors). Furthermore, the OR1Q1 gene has been implicated in the development of certain cancers, including lung and breast cancer, where it is thought to play a role in the regulation of cell growth and differentiation. Additionally, the OR1Q1 gene has been shown to be involved in the regulation of immune responses, where it is thought to play a role in modulating the activity of immune cells, including T cells and macrophages. Overall, the OR1Q1 gene is a critical component of the olfactory system, and its dysregulation can have significant implications for our understanding of olfactory disorders and diseases. In conclusion, the OR1Q1 gene is a fascinating gene that plays a critical role in our ability to perceive odors. Its involvement in several key pathways, including the detection of chemical stimulus involved in sensory perception of smell and G protein-coupled receptor activity, highlights its importance in modulating sensory perception. Furthermore, its implications for olfactory disorders and diseases, including anosmia and hyposmia, and its potential role in cancer development and immune regulation, underscore its significance as a gene of interest for further research.

Genular Protein ID: 408657162

Symbol: OR1Q1_HUMAN

Name: Olfactory receptor 1Q1

UniProtKB Accession Codes:

Q15612 Q6IFN4 Q8NGR7 Q96R82

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 5 Ensembl 1 GO 6 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 InterPro 3 KEGG 1 MANE-Select 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 2 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RNAct 1 Reactome 1 RefSeq 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 12213199

Title: DEFOG: a practical scheme for deciphering families of genes.

PubMed ID: 12213199

DOI: 10.1006/geno.2002.6830

PubMed ID: 9119360

Title: Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species.

PubMed ID: 9119360

DOI: 10.1006/geno.1996.4490

PubMed ID: 14983052

Title: The human olfactory receptor gene family.

PubMed ID: 14983052

DOI: 10.1073/pnas.0307882100

Sequence Information:

  • Length: 314
  • Mass: 35598
  • Checksum: 6CFA2B4C946F0EBB
  • Sequence:
    • MDNSNWTSVS HFVLLGISTH PEEQIPLFLV FSLMYAINIS GNLAIITLIL SAPRLHIPMY 
IFLSNLALTD ICFTSTTVPK MLQIIFSPTK VISYTGCLAQ TYFFICFAVM ENFILAVMAY 
DRYIAICHPF HYTMILTRML CVKMVVMCHA LSHLHAMLHT FLIGQLIFCA DNRIPHFFCD 
LYALMKISCT STYLNTLMIH TEGAVVISGA LAFITASYAC IILVVLRIPS AKGRWKTFST 
CGSHLTVVAI FYGTLSWVYF RPLSSYSVTK GRIITVVYTV VTPMLNPFIY SLRNGDVKGG 
FMKWMSRMQT FFFR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.