Details for: GRM7
Associated with
Cells (max top 100)
(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: Purkinje cell (CL0000121)
Fold Change: 7.02
Marker Score: 236942 - Cell Name: epithelial cell of alveolus of lung (CL0010003)
Fold Change: 3.78
Marker Score: 1695 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 3.08
Marker Score: 8788 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 2.9
Marker Score: 1116 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 2.78
Marker Score: 21286 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 2.77
Marker Score: 4656 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 2.74
Marker Score: 103902.5 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 2.72
Marker Score: 12580 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 2.45
Marker Score: 48782 - Cell Name: sympathetic neuron (CL0011103)
Fold Change: 2.4
Marker Score: 792 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 2.37
Marker Score: 2926 - Cell Name: neuron (CL0000540)
Fold Change: 2.36
Marker Score: 9601 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 2.34
Marker Score: 34994.5 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 2.09
Marker Score: 76955.5 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.08
Marker Score: 127616 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 1.94
Marker Score: 4638 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.93
Marker Score: 7478 - Cell Name: brainstem motor neuron (CL2000047)
Fold Change: 1.92
Marker Score: 1116 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 1.92
Marker Score: 18067 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.71
Marker Score: 14714 - Cell Name: macroglial cell (CL0000126)
Fold Change: 1.7
Marker Score: 3916 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.66
Marker Score: 2557 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.61
Marker Score: 1168 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 1.49
Marker Score: 897 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 1.47
Marker Score: 3460 - Cell Name: mural cell (CL0008034)
Fold Change: 1.46
Marker Score: 167955 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.42
Marker Score: 14663 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 1.39
Marker Score: 778 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 1.39
Marker Score: 2819 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 1.37
Marker Score: 868 - Cell Name: renal beta-intercalated cell (CL0002201)
Fold Change: 1.34
Marker Score: 423 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.3
Marker Score: 12321.5 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 1.26
Marker Score: 854 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 1.2
Marker Score: 701 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 1.19
Marker Score: 374 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 1.17
Marker Score: 487 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 1.16
Marker Score: 24790 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.15
Marker Score: 17976 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 1.15
Marker Score: 4805 - Cell Name: granulosa cell (CL0000501)
Fold Change: 1.14
Marker Score: 11519 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 1.11
Marker Score: 1278 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 1.1
Marker Score: 4571 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 1.1
Marker Score: 724.5 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: 1.09
Marker Score: 411 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 1.04
Marker Score: 795 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 1.02
Marker Score: 708 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 1.01
Marker Score: 320 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71805 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48030 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.99
Marker Score: 508 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30407 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.98
Marker Score: 462 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2412 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.94
Marker Score: 434 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.93
Marker Score: 374 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 0.93
Marker Score: 241 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: 0.93
Marker Score: 3866 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.92
Marker Score: 5261 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2738 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.9
Marker Score: 325 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 0.9
Marker Score: 537 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5285 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.87
Marker Score: 1474 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.84
Marker Score: 402 - Cell Name: ciliated cell (CL0000064)
Fold Change: 0.82
Marker Score: 2815 - Cell Name: lens fiber cell (CL0011004)
Fold Change: 0.78
Marker Score: 248 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1261 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.76
Marker Score: 396 - Cell Name: brush cell (CL0002204)
Fold Change: 0.76
Marker Score: 695 - Cell Name: multi-ciliated epithelial cell (CL0005012)
Fold Change: 0.73
Marker Score: 1386 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.72
Marker Score: 462 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.7
Marker Score: 179 - Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
Fold Change: 0.7
Marker Score: 6052 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: 0.68
Marker Score: 6912 - Cell Name: granule cell (CL0000120)
Fold Change: 0.68
Marker Score: 5099 - Cell Name: microglial cell (CL0000129)
Fold Change: 0.67
Marker Score: 1216 - Cell Name: mature microglial cell (CL0002629)
Fold Change: 0.64
Marker Score: 233 - Cell Name: neuronal receptor cell (CL0000006)
Fold Change: 0.62
Marker Score: 273 - Cell Name: astrocyte (CL0000127)
Fold Change: 0.6
Marker Score: 521 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.58
Marker Score: 462 - Cell Name: rod bipolar cell (CL0000751)
Fold Change: 0.57
Marker Score: 298 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.57
Marker Score: 150 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 0.56
Marker Score: 501 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 0.55
Marker Score: 174 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.55
Marker Score: 1040 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 0.54
Marker Score: 7246 - Cell Name: stellate neuron (CL0000122)
Fold Change: 0.54
Marker Score: 2906 - Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 0.54
Marker Score: 1465 - Cell Name: starburst amacrine cell (CL0004232)
Fold Change: 0.53
Marker Score: 151 - Cell Name: meningeal macrophage (CL0000879)
Fold Change: 0.51
Marker Score: 144 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 0.51
Marker Score: 213 - Cell Name: bipolar neuron (CL0000103)
Fold Change: 0.51
Marker Score: 171 - Cell Name: mesangial cell (CL0000650)
Fold Change: 0.51
Marker Score: 613 - Cell Name: macrophage (CL0000235)
Fold Change: 0.5
Marker Score: 555 - Cell Name: pro-B cell (CL0000826)
Fold Change: 0.49
Marker Score: 475 - Cell Name: CNS interneuron (CL0000402)
Fold Change: 0.49
Marker Score: 236 - Cell Name: Leydig cell (CL0000178)
Fold Change: 0.47
Marker Score: 509 - Cell Name: Unknown (CL0002371)
Fold Change: 0.47
Marker Score: 496 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.45
Marker Score: 2686 - Cell Name: acinar cell (CL0000622)
Fold Change: 0.43
Marker Score: 300
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Other Information
Genular Protein ID: 3839496233
Symbol: GRM7_HUMAN
Name: Metabotropic glutamate receptor 7
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8840028
Title: Human metabotropic glutamate receptor type 7: molecular cloning and mRNA distribution in the CNS.
PubMed ID: 8840028
PubMed ID: 9144652
Title: A novel splice variant of a metabotropic glutamate receptor, human mGluR7b.
PubMed ID: 9144652
PubMed ID: 9473604
Title: Group III human metabotropic glutamate receptors 4, 7 and 8: molecular cloning, functional expression, and comparison of pharmacological properties in RGT cells.
PubMed ID: 9473604
PubMed ID: 12052533
Title: Characterization of three novel isoforms of the metabotropic glutamate receptor 7 (GRM7).
PubMed ID: 12052533
PubMed ID: 27435318
Title: Exome sequencing in mostly consanguineous Arab families with neurologic disease provides a high potential molecular diagnosis rate.
PubMed ID: 27435318
PubMed ID: 28097321
Title: Diagnostic yield and novel candidate genes by exome sequencing in 152 consanguineous families with neurodevelopmental disorders.
PubMed ID: 28097321
PubMed ID: 32286009
Title: Biallelic GRM7 variants cause epilepsy, microcephaly, and cerebral atrophy.
PubMed ID: 32286009
DOI: 10.1002/acn3.51003
PubMed ID: 33476302
Title: A GRM7 mutation associated with developmental delay reduces mGlu7 expression and produces neurological phenotypes.
PubMed ID: 33476302
PubMed ID: 33500274
Title: Pathogenic GRM7 mutations associated with neurodevelopmental disorders impair axon outgrowth and presynaptic terminal development.
PubMed ID: 33500274
PubMed ID: 11163549
Title: Polymorphisms in the genes for mGluR types 7 and 8: association studies with schizophrenia.
PubMed ID: 11163549
Sequence Information:
- Length: 915
- Mass: 102251
- Checksum: CFF94E06BF7F4919
- Sequence:
MVQLRKLLRV LTLMKFPCCV LEVLLCALAA AARGQEMYAP HSIRIEGDVT LGGLFPVHAK GPSGVPCGDI KRENGIHRLE AMLYALDQIN SDPNLLPNVT LGARILDTCS RDTYALEQSL TFVQALIQKD TSDVRCTNGE PPVFVKPEKV VGVIGASGSS VSIMVANILR LFQIPQISYA STAPELSDDR RYDFFSRVVP PDSFQAQAMV DIVKALGWNY VSTLASEGSY GEKGVESFTQ ISKEAGGLCI AQSVRIPQER KDRTIDFDRI IKQLLDTPNS RAVVIFANDE DIKQILAAAK RADQVGHFLW VGSDSWGSKI NPLHQHEDIA EGAITIQPKR ATVEGFDAYF TSRTLENNRR NVWFAEYWEE NFNCKLTISG SKKEDTDRKC TGQERIGKDS NYEQEGKVQF VIDAVYAMAH ALHHMNKDLC ADYRGVCPEM EQAGGKKLLK YIRNVNFNGS AGTPVMFNKN GDAPGRYDIF QYQTTNTSNP GYRLIGQWTD ELQLNIEDMQ WGKGVREIPA SVCTLPCKPG QRKKTQKGTP CCWTCEPCDG YQYQFDEMTC QHCPYDQRPN ENRTGCQDIP IIKLEWHSPW AVIPVFLAML GIIATIFVMA TFIRYNDTPI VRASGRELSY VLLTGIFLCY IITFLMIAKP DVAVCSFRRV FLGLGMCISY AALLTKTNRI YRIFEQGKKS VTAPRLISPT SQLAITSSLI SVQLLGVFIW FGVDPPNIII DYDEHKTMNP EQARGVLKCD ITDLQIICSL GYSILLMVTC TVYAIKTRGV PENFNEAKPI GFTMYTTCIV WLAFIPIFFG TAQSAEKLYI QTTTLTISMN LSASVALGML YMPKVYIIIF HPELNVQKRK RSFKAVVTAA TMSSRLSHKP SDRPNGEAKT ELCENVDPNS PAAKKKYVSY NNLVI
Genular Protein ID: 2725404079
Symbol: B9EGG9_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 922
- Mass: 103054
- Checksum: C12498D53EC3787E
- Sequence:
MVQLRKLLRV LTLMKFPCCV LEVLLCALAA AARGQEMYAP HSIRIEGDVT LGGLFPVHAK GPSGVPCGDI KRENGIHRLE AMLYALDQIN SDPNLLPNVT LGARILDTCS RDTYALEQSL TFVQALIQKD TSDVRCTNGE PPVFVKPEKV VGVIGASGSS VSIMVANILR LFQIPQISYA STAPELSDDR RYDFFSRVVP PDSFQAQAMV DIVKALGWNY VSTLASEGSY GEKGVESFTQ ISKEAGGLCI AQSVRIPQER KDRTIDFDRI IKQLLDTPNS RAVVIFANDE DIKQILAAAK RADQVGHFLW VGSDSWGSKI NPLHQHEDIA EGAITIQPKR ATVEGFDAYF TSRTLENNRR NVWFAEYWEE NFNCKLTISG SKKEDTDRKC TGQERIGKDS NYEQEGKVQF VIDAVYAMAH ALHHMNKDLC ADFRGVCPEM EQAGGKKLLK YIRNVNFNGS AGTPVMFNKN GDAPGRYDIF QYQTTNTSNP GYRLIGQWTD ELQLNIEDMQ WGKGVREIPA SVCTLPCKPG QRKKTQKGTP CCWTCEPCDG YQYQFDEMTC QHCPYDQRPN ENRTGCQDIP IIKLEWHSPW AVIPVFLAML GIIATIFVMA TFIRYNDTPI VRASGRELSY VLLTGIFLCY IITFLMIAKP DVAVCSFRRV FLGLGMCISY AALLTKTNRI YRIFEQGKKS VTAPRLISPT SQLAITSSLI SVQLLGVFIW FGVDPPNIII DYDEHKTMNP EQARGVLKCD ITDLQIICSL GYSILLMVTC TVYAIKTRGV PENFNEAKPI GFTMYTTCIV WLAFIPIFFG TAQSAEKLYI QTTTLTISMN LSASVALGML YMPKVYIIIF HPELNVQKRK RSFKAVVTAA TMSSRLSHKP SDRPNGEAKT ELCENVDPNN CIPPVRKSVQ KSVTWYTIPP TV
Genular Protein ID: 3099994351
Symbol: B2R693_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 915
- Mass: 102162
- Checksum: 56A4BE44546C77F0
- Sequence:
MVQLRKLLRV LTLMKFPCCV LEVLLCALAA AARGQEMYAP HSIRIEGDVT LGGLFPVHAK GPSGVPCGDI KRENGIHRLE AMLYALDQIN SDPNLLPNVT LGARILDTCS RDTYALEQSL TFVQALIQKD TSDVRCTNGE PPVFVKPEKV VGVIGASGSS VSIMVANILR LFQIPQISYA STAPELSDDR RYDFFSRVVP PDSFQAQAMV DIVKALGWNY VSTLASEGSY GEKGVESFTQ ISKEAGGLCI AQSVRIPQER KDRTIDFDRI IKQLLDTPNS RAVVIFANDE DIKQILAAAK RADQVGHFLW VGSDSWGSKI NPLHQHEDIA EGAITIQPKR ATVEGFDAYF TSRTLENNRR NVWFAEYWEE NFNCKLTISG SKKEDTDRKC TGQERIGKDS NYEQEGKVQF VIDAVYAMAH ALHHMNKDLC ADFRGVCPEM EQAGGKKLLK YIRNVNFNGS AGTPVMFNKN GDAPGRYDIF QYQTTNTSNP GYRLIGQWTD ELQLNIEDMQ WGKGVREIPA SVCTLPCKPG QRKKTQKGTP CCLTCEPCDG YQYQFDEMTC QHCPYDQRPN ENRTGCQDIP IIKLEWHSPW AVIPVFLAML GIIATIFVMA TFIRYNDTPI VRASGRELSY VLLTGIFLCY IITFLMIAKP DVAVCSFRRV FLGLGMCISY AALLTKTNRI YRIFEQGKKS VTAPRLISPT SQLAITSSLI SVQLLGVFIW FGVDPPNIII DYDEHKTMNP EQARGVLKCD ITDLQIICSL GYSILLMVTC TVYAIKTRGV PENFNEAKPI GFTMYTTCIV WLAFIPIFFG TAQSAEKLYI QTTTLTISMN LSASVALGML YMPKVYIIIF HPELNVQKRK RSFKAVVTAA TMSSRLSHKP SDRPNGEAKT ELCENVDPNS PAAKKKYVSY NNLVI
Genular Protein ID: 2189542084
Symbol: Q59G95_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 656
- Mass: 74041
- Checksum: 6F05EC16F30EA2E2
- Sequence:
GGLCIAQSVR IPQERKDRTI DFDRIIKQLL DTPNSRAVVI FANDEDIKQI LAAAKRADQV GHFLWVGSDS WGSKINPLHQ HEDIAEGAIT IQPKRATVEG FDAYFTSRTL ENNRRNVWFA EYWEENFNCK LTISGSKKED TDRKCTGQER IGKDSNYEQE GKVQFVIDAV YAMAHALHHM NKDLCADYRG VCPEMEQAGG KKLLKYIRNV NFNGSAGTPV MFNKNGDAPG RYDIFQYQTT NTSNPGYRLI GQWTDELQLN IEDMQWGKGV REIPASVCTL PCKPGQRKKT QKGTPCCWTC EPCDGYQYQF DEMTCQHCPY DQRPNENRTG CQDIPIIKLE WHSPWAVIPV FLAMLGIIAT IFVMATFIRY NDTPIVRASG RELSYVLLTG IFLCYIITFL MIAKPDVAVC SFRRVFLGLG MCISYAALLT KTNRIYRIFE QGKKSVTAPR LISPTSQLAI TSSLISVQLL GVFIWFGVDP PNIIIDYDEH KTMNPEQARG VLKCDITDLQ IICSLGYSIL LMVTCTVYAI KTRGVPENFN EAKPIGFTMY TTCIVWLAFI PIFFGTAQSA EKLYIQTTTL TISMNLSASV ALGMLYMPKV YIIIFHPELN VQKRKRSFKA VVTAATMSSR LSHKPSDRPN GEAKTELCEN VDPNSK
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.