Details for: TRNT

Gene ID: 4576

Symbol: TRNT

Ensembl ID: ENSG00000210195

Description: tRNA-Thr

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 6.5369
    Cell Significance Index: 192.5400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 3.5314
    Cell Significance Index: -9.4600
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 3.2691
    Cell Significance Index: 81.6500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 2.7450
    Cell Significance Index: 124.4200
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 2.0809
    Cell Significance Index: 31.1800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 2.0478
    Cell Significance Index: 59.0000
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.5932
    Cell Significance Index: 22.6800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.1895
    Cell Significance Index: 55.4600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.1519
    Cell Significance Index: 59.8400
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 1.0646
    Cell Significance Index: 13.7100
  • Cell Name: adipocyte (CL0000136)
    Fold Change: 0.8162
    Cell Significance Index: 10.8800
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: 0.7158
    Cell Significance Index: 12.3400
  • Cell Name: large intestine goblet cell (CL1000320)
    Fold Change: 0.6330
    Cell Significance Index: 6.8600
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 0.5489
    Cell Significance Index: 5.6800
  • Cell Name: retina horizontal cell (CL0000745)
    Fold Change: 0.2741
    Cell Significance Index: 3.4400
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: 0.2429
    Cell Significance Index: 2.3500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0809
    Cell Significance Index: 5.1000
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 0.0453
    Cell Significance Index: 0.4900
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 0.0431
    Cell Significance Index: 0.4500
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: 0.0311
    Cell Significance Index: 0.4300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.0027
    Cell Significance Index: 0.7700
  • Cell Name: CD8-positive, alpha-beta thymocyte (CL0000811)
    Fold Change: 0.0022
    Cell Significance Index: 0.0200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0004
    Cell Significance Index: 0.0600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0055
    Cell Significance Index: -10.4300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0065
    Cell Significance Index: -11.9900
  • Cell Name: eosinophil (CL0000771)
    Fold Change: -0.0068
    Cell Significance Index: -0.0600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0078
    Cell Significance Index: -11.9900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0088
    Cell Significance Index: -1.0100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0125
    Cell Significance Index: -7.9600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0129
    Cell Significance Index: -9.5200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0217
    Cell Significance Index: -0.4700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0234
    Cell Significance Index: -10.6400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0455
    Cell Significance Index: -1.6000
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: -0.0477
    Cell Significance Index: -0.4200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0527
    Cell Significance Index: -10.5700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0664
    Cell Significance Index: -9.6500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0763
    Cell Significance Index: -2.4300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0779
    Cell Significance Index: -2.1200
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0974
    Cell Significance Index: -2.4300
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1045
    Cell Significance Index: -3.4200
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: -0.1053
    Cell Significance Index: -1.3600
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.1120
    Cell Significance Index: -2.4200
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.1142
    Cell Significance Index: -2.3700
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.1190
    Cell Significance Index: -2.3900
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.1204
    Cell Significance Index: -2.3800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1220
    Cell Significance Index: -7.4800
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.1254
    Cell Significance Index: -2.5000
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.1411
    Cell Significance Index: -2.4400
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1593
    Cell Significance Index: -3.3800
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: -0.1666
    Cell Significance Index: -1.6700
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: -0.1890
    Cell Significance Index: -1.9600
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.1911
    Cell Significance Index: -4.0700
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: -0.2011
    Cell Significance Index: -2.7900
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: -0.2094
    Cell Significance Index: -2.2900
  • Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
    Fold Change: -0.2164
    Cell Significance Index: -2.1800
  • Cell Name: fast muscle cell (CL0000190)
    Fold Change: -0.2298
    Cell Significance Index: -3.0100
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.2338
    Cell Significance Index: -3.1900
  • Cell Name: neuroplacodal cell (CL0000032)
    Fold Change: -0.2347
    Cell Significance Index: -2.8900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2492
    Cell Significance Index: -7.9800
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: -0.2515
    Cell Significance Index: -2.7300
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.2887
    Cell Significance Index: -7.3600
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.3081
    Cell Significance Index: -3.2500
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.3133
    Cell Significance Index: -4.9700
  • Cell Name: ciliated epithelial cell (CL0000067)
    Fold Change: -0.3221
    Cell Significance Index: -3.1900
  • Cell Name: ionocyte (CL0005006)
    Fold Change: -0.3386
    Cell Significance Index: -3.5400
  • Cell Name: salivary gland cell (CL0009005)
    Fold Change: -0.3489
    Cell Significance Index: -4.3300
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.3838
    Cell Significance Index: -12.1400
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.3912
    Cell Significance Index: -6.6500
  • Cell Name: myeloid dendritic cell (CL0000782)
    Fold Change: -0.3927
    Cell Significance Index: -3.0800
  • Cell Name: DN4 thymocyte (CL0000808)
    Fold Change: -0.3969
    Cell Significance Index: -2.9900
  • Cell Name: erythroid lineage cell (CL0000764)
    Fold Change: -0.4104
    Cell Significance Index: -4.5300
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: -0.4113
    Cell Significance Index: -7.0300
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.4235
    Cell Significance Index: -5.0400
  • Cell Name: tracheal goblet cell (CL1000329)
    Fold Change: -0.4246
    Cell Significance Index: -3.5100
  • Cell Name: intestinal crypt stem cell of large intestine (CL0009016)
    Fold Change: -0.4438
    Cell Significance Index: -3.8800
  • Cell Name: retinal pigment epithelial cell (CL0002586)
    Fold Change: -0.4474
    Cell Significance Index: -4.8100
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: -0.4519
    Cell Significance Index: -5.8100
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.4670
    Cell Significance Index: -9.1300
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.4692
    Cell Significance Index: -12.0600
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: -0.4704
    Cell Significance Index: -4.3800
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.4845
    Cell Significance Index: -5.7800
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.4934
    Cell Significance Index: -6.0700
  • Cell Name: stromal cell (CL0000499)
    Fold Change: -0.5011
    Cell Significance Index: -5.1200
  • Cell Name: memory B cell (CL0000787)
    Fold Change: -0.5452
    Cell Significance Index: -5.8000
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -0.5494
    Cell Significance Index: -6.6600
  • Cell Name: mucus secreting cell (CL0000319)
    Fold Change: -0.5560
    Cell Significance Index: -5.6800
  • Cell Name: macrophage (CL0000235)
    Fold Change: -0.5622
    Cell Significance Index: -5.7400
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.5646
    Cell Significance Index: -7.8300
  • Cell Name: monocyte (CL0000576)
    Fold Change: -0.5716
    Cell Significance Index: -6.5800
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.5793
    Cell Significance Index: -6.8400
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: -0.5820
    Cell Significance Index: -3.6600
  • Cell Name: neutrophil (CL0000775)
    Fold Change: -0.5836
    Cell Significance Index: -7.2900
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: -0.5840
    Cell Significance Index: -5.6300
  • Cell Name: acinar cell (CL0000622)
    Fold Change: -0.6011
    Cell Significance Index: -7.5500
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.6041
    Cell Significance Index: -7.9000
  • Cell Name: secretory cell (CL0000151)
    Fold Change: -0.6193
    Cell Significance Index: -4.3000
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: -0.6196
    Cell Significance Index: -7.2900
  • Cell Name: mast cell (CL0000097)
    Fold Change: -0.6231
    Cell Significance Index: -8.2000
  • Cell Name: naive B cell (CL0000788)
    Fold Change: -0.6401
    Cell Significance Index: -6.7400
  • Cell Name: CD141-positive myeloid dendritic cell (CL0002394)
    Fold Change: -0.6488
    Cell Significance Index: -7.0200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** TRNT is a small, non-coding RNA molecule that belongs to the tRNA family. It is approximately 50 nucleotides in length and is highly conserved across species, suggesting its essential role in fundamental cellular processes. The expression of TRNT is widespread, with significant levels detected in various cell types, including CD4-positive and CD8-positive T cells, goblet cells, absorptive cells, and neoplastic cells. This broad expression pattern underscores the importance of TRNT in maintaining cellular homeostasis and regulating immune responses. **Pathways and Functions:** TRNT has been implicated in several key cellular pathways, including: 1. **Immune regulation:** TRNT modulates the activity of immune cells, including T cells and mast cells, by regulating the expression of genes involved in immune response and cellular differentiation. 2. **Cellular differentiation:** TRNT plays a crucial role in the differentiation of stem cells into various cell types, including epithelial cells and immune cells. 3. **Tumor progression:** TRNT has been shown to be overexpressed in several types of cancer, including colon cancer, and may contribute to tumorigenesis by regulating cell growth, apoptosis, and metastasis. 4. **RNA processing:** TRNT is involved in the regulation of RNA processing, including splicing and transcriptional regulation, which is essential for the expression of genes involved in cellular homeostasis. **Clinical Significance:** The clinical significance of TRNT is multifaceted: 1. **Immune-related disorders:** TRNT dysregulation may contribute to the development of immune-related disorders, such as autoimmune diseases and cancer. 2. **Cancer diagnosis and prognosis:** The expression of TRNT in tumor cells may serve as a diagnostic biomarker and prognostic indicator for cancer patients. 3. **Therapeutic targeting:** TRNT may be a potential target for cancer therapy, as its dysregulation has been implicated in tumorigenesis. 4. **Cellular homeostasis:** TRNT plays a crucial role in maintaining cellular homeostasis, and its dysregulation may contribute to various diseases, including autoimmune disorders and cancer. In conclusion, the TRNT gene is a complex and multifunctional molecule that plays a critical role in regulating immune responses, cellular differentiation, and tumor progression. Further research is necessary to fully elucidate the functional significance of TRNT and its potential applications in cancer therapy and disease diagnosis.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.