Details for: ANTXR1
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 15.41rCSI 37.04%PRS 89.3
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CSI 14.52rCSI 29.47%PRS 69.13
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CSI 13.04rCSI 44.68%PRS 74.9
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CSI 12.07rCSI 45.62%PRS 73.6
-
CSI 11.93rCSI 31.47%PRS 92.31
-
CSI 11.74rCSI 15.13%PRS 74.44
-
CSI 11.11rCSI 15.2%PRS 79.88
-
CSI 10.01rCSI 36.03%PRS 71.32
-
CSI 10.01rCSI 26.75%PRS 81.55
-
CSI 9.94rCSI 15.86%PRS 80.16
-
CSI 9.31rCSI 22.28%PRS 76.68
-
CSI 8.77rCSI 22.55%PRS 84.11
-
CSI 8.61rCSI 15.64%PRS 80.84
-
CSI 8.31rCSI 10.66%PRS 84.45
-
CSI 8.17rCSI 13.37%PRS 79.77
-
CSI 7.96rCSI 46.84%PRS 73.82
-
CSI 7.63rCSI 6.2%PRS 87.27
-
CSI 7.6rCSI 22.03%PRS 78.85
-
CSI 7.36rCSI 18.67%PRS 80.6
-
CSI 6.83rCSI 21.36%PRS 74.77
-
CSI 6.52rCSI 14.87%PRS 80.8
-
CSI 6.02rCSI 8.36%PRS 86.38
-
CSI 5.97rCSI 7.16%PRS 86.65
-
CSI 5.71rCSI 7.34%PRS 78.97
-
CSI 5.64rCSI 6.52%PRS 80.67
-
CSI 5.53rCSI 15.2%PRS 91.69
-
CSI 5.49rCSI 12.67%PRS 77.99
-
CSI 5.15rCSI 4.07%PRS 79.68
-
CSI 5.13rCSI 6.38%PRS 71.15
-
CSI 5rCSI 14.06%PRS 83.57
-
CSI 4.83rCSI 6.6%PRS 91.2
-
CSI 4.65rCSI 4.01%PRS 87.5
-
CSI 4.65rCSI 6.44%PRS 84.48
-
CSI 4.55rCSI 11.51%PRS 90.91
-
CSI 4.53rCSI 3.8%PRS 89.14
-
CSI 4.52rCSI 9.39%PRS 85.73
-
CSI 4.04rCSI 5.94%PRS 82.1
-
CSI 4rCSI 3.72%PRS 88.99
-
CSI 3.99rCSI 3.1%PRS 90.91
-
CSI 3.97rCSI 10.35%PRS 89.16
-
CSI 3.91rCSI 6.85%PRS 83.59
-
CSI 3.89rCSI 11.06%PRS 83.89
-
CSI 3.62rCSI 2.68%PRS 83.33
-
CSI 3.5rCSI 13.1%PRS 82.38
-
CSI 3.43rCSI 6.88%PRS 80.93
-
CSI 3.36rCSI 3.5%PRS 86.85
-
CSI 3.28rCSI 5.27%PRS 74.44
-
CSI 3.26rCSI 3.89%PRS 73.48
-
CSI 3.15rCSI 3.26%PRS 90.03
-
CSI 2.98rCSI 9.53%PRS 85.96
-
CSI 2.93rCSI 3.21%PRS 89.38
-
CSI 2.87rCSI 6.98%PRS 71.08
-
CSI 2.83rCSI 6.25%PRS 76.21
-
CSI 2.75rCSI 6.57%PRS 90.41
-
CSI 2.75rCSI 6.56%PRS 82.77
-
CSI 2.74rCSI 8.01%PRS 94.32
-
CSI 2.68rCSI 12.82%PRS 88.37
-
CSI 2.64rCSI 3.06%PRS 89.17
-
CSI 2.62rCSI 3.5%PRS 85.38
-
CSI 2.55rCSI 3.25%PRS 91.86
-
CSI 2.54rCSI 6.46%PRS 82.39
-
CSI 2.54rCSI 11.19%PRS 76.88
-
CSI 2.53rCSI 4.02%PRS 82.53
-
CSI 2.5rCSI 4.19%PRS 73.33
-
CSI 2.48rCSI 3.63%PRS 91.64
-
CSI 2.41rCSI 7.82%PRS 85.89
-
CSI 2.4rCSI 3.79%PRS 88.77
-
CSI 2.36rCSI 17.33%PRS 77.98
-
CSI 2.35rCSI 6.13%PRS 82.01
-
CSI 2.3rCSI 6.79%PRS 86.95
-
CSI 2.19rCSI 2.8%PRS 89.85
-
CSI 2.07rCSI 2.97%PRS 79.36
-
CSI 2rCSI 48%PRS 70.91
-
CSI 2rCSI 48.21%PRS 71.33
-
CSI 1.95rCSI 5.37%PRS 84.5
-
CSI 1.92rCSI 2.94%PRS 87.34
-
CSI 1.89rCSI 20.7%PRS 90.55
-
CSI 1.88rCSI 6.1%PRS 85.08
-
CSI 1.74rCSI 3.9%PRS 74
-
CSI 1.71rCSI 3.01%PRS 91.04
-
CSI 1.68rCSI 3.46%PRS 75.77
-
CSI 1.61rCSI 6.13%PRS 80.67
-
CSI 1.57rCSI 5.17%PRS 75.67
-
CSI 1.45rCSI 4.54%PRS 76.73
-
CSI 1.45rCSI 3.18%PRS 90.51
-
CSI 1.31rCSI 4.39%PRS 73.62
-
CSI 1.28rCSI 5.01%PRS 69.23
-
CSI 1.2rCSI 9.19%PRS 88.08
-
CSI 1.09rCSI 1.92%PRS 72.79
-
CSI 1.07rCSI 4.48%PRS 90.5
-
CSI 1rCSI 2.88%PRS 87.05
-
CSI 0.99rCSI 5.59%PRS 76.47
-
CSI 0.88rCSI 3.59%PRS 93.44
-
CSI 0.88rCSI 7.4%PRS 74.89
-
CSI 0.83rCSI 4.37%PRS 88.54
-
CSI 0.6rCSI 4.85%PRS 83.96
-
CSI 0.58rCSI 3.37%PRS 89.86
-
CSI 0.55rCSI 2.46%PRS 88.61
-
CSI 0.27rCSI 5.52%PRS 78.6
-
CSI 0.25rCSI 5.15%PRS 79.41
-
CSI 0.2rCSI 2.0%PRS 78.8%
-
CSI 0.3rCSI 5.2%PRS 79.4%
-
CSI 0.3rCSI 5.5%PRS 78.6%
-
CSI 0.6rCSI 2.5%PRS 88.6%
-
CSI 0.6rCSI 3.4%PRS 89.9%
-
CSI 0.6rCSI 4.9%PRS 84.0%
-
CSI 0.8rCSI 4.4%PRS 88.5%
-
CSI 0.9rCSI 7.4%PRS 74.9%
-
CSI 0.9rCSI 3.6%PRS 93.4%
-
CSI 1.0rCSI 5.6%PRS 76.5%
-
CSI 1.0rCSI 2.9%PRS 87.1%
-
CSI 1.1rCSI 4.5%PRS 90.5%
-
CSI 1.1rCSI 1.9%PRS 72.8%
-
CSI 1.2rCSI 9.2%PRS 88.1%
-
CSI 1.3rCSI 5.0%PRS 69.2%
-
CSI 1.3rCSI 4.4%PRS 73.6%
-
CSI 1.5rCSI 3.2%PRS 90.5%
-
CSI 1.5rCSI 4.5%PRS 76.7%
-
CSI 1.6rCSI 5.2%PRS 75.7%
-
CSI 1.6rCSI 6.1%PRS 80.7%
-
CSI 1.7rCSI 3.5%PRS 75.8%
-
CSI 1.7rCSI 3.0%PRS 91.0%
-
CSI 1.7rCSI 3.9%PRS 74.0%
-
CSI 1.9rCSI 6.1%PRS 85.1%
-
CSI 1.9rCSI 20.7%PRS 90.6%
-
CSI 1.9rCSI 2.9%PRS 87.3%
-
CSI 2.0rCSI 5.4%PRS 84.5%
-
CSI 2.0rCSI 48.2%PRS 71.3%
-
CSI 2.0rCSI 48.0%PRS 70.9%
-
CSI 2.1rCSI 3.0%PRS 79.4%
-
CSI 2.2rCSI 2.8%PRS 89.9%
-
CSI 2.3rCSI 6.8%PRS 87.0%
-
CSI 2.4rCSI 6.1%PRS 82.0%
-
CSI 2.4rCSI 17.3%PRS 78.0%
-
CSI 2.4rCSI 3.8%PRS 88.8%
-
CSI 2.4rCSI 7.8%PRS 85.9%
-
CSI 2.5rCSI 3.6%PRS 91.6%
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CSI 2.5rCSI 4.2%PRS 73.3%
-
CSI 2.5rCSI 4.0%PRS 82.5%
-
CSI 2.5rCSI 11.2%PRS 76.9%
-
CSI 2.5rCSI 6.5%PRS 82.4%
-
CSI 2.6rCSI 3.3%PRS 91.9%
-
CSI 2.6rCSI 3.5%PRS 85.4%
-
CSI 2.6rCSI 3.1%PRS 89.2%
-
CSI 2.7rCSI 12.8%PRS 88.4%
-
CSI 2.7rCSI 8.0%PRS 94.3%
-
CSI 2.8rCSI 6.6%PRS 82.8%
-
CSI 2.8rCSI 6.6%PRS 90.4%
-
CSI 2.8rCSI 6.3%PRS 76.2%
-
CSI 2.9rCSI 7.0%PRS 71.1%
-
CSI 2.9rCSI 3.2%PRS 89.4%
-
CSI 3.0rCSI 9.5%PRS 86.0%
-
CSI 3.2rCSI 3.3%PRS 90.0%
-
CSI 3.3rCSI 3.9%PRS 73.5%
-
CSI 3.3rCSI 5.3%PRS 74.4%
-
CSI 3.4rCSI 3.5%PRS 86.9%
-
CSI 3.4rCSI 6.9%PRS 80.9%
-
CSI 3.5rCSI 13.1%PRS 82.4%
-
CSI 3.6rCSI 2.7%PRS 83.3%
-
CSI 3.9rCSI 11.1%PRS 83.9%
-
CSI 3.9rCSI 6.9%PRS 83.6%
-
CSI 4.0rCSI 10.4%PRS 89.2%
-
CSI 4.0rCSI 3.1%PRS 90.9%
-
CSI 4.0rCSI 3.7%PRS 89.0%
-
CSI 4.0rCSI 5.9%PRS 82.1%
-
CSI 4.5rCSI 9.4%PRS 85.7%
-
CSI 4.5rCSI 3.8%PRS 89.1%
-
CSI 4.6rCSI 11.5%PRS 90.9%
-
CSI 4.7rCSI 6.4%PRS 84.5%
-
CSI 4.7rCSI 4.0%PRS 87.5%
-
CSI 4.8rCSI 6.6%PRS 91.2%
-
CSI 5.0rCSI 14.1%PRS 83.6%
-
CSI 5.1rCSI 6.4%PRS 71.2%
-
CSI 5.2rCSI 4.1%PRS 79.7%
-
CSI 5.5rCSI 12.7%PRS 78.0%
-
CSI 5.5rCSI 15.2%PRS 91.7%
-
CSI 5.6rCSI 6.5%PRS 80.7%
-
CSI 5.7rCSI 7.3%PRS 79.0%
-
CSI 6.0rCSI 7.2%PRS 86.7%
-
CSI 6.0rCSI 8.4%PRS 86.4%
-
CSI 6.5rCSI 14.9%PRS 80.8%
-
CSI 6.8rCSI 21.4%PRS 74.8%
-
CSI 7.4rCSI 18.7%PRS 80.6%
-
CSI 7.6rCSI 22.0%PRS 78.9%
-
CSI 7.6rCSI 6.2%PRS 87.3%
-
CSI 8.0rCSI 46.8%PRS 73.8%
-
CSI 8.2rCSI 13.4%PRS 79.8%
-
CSI 8.3rCSI 10.7%PRS 84.5%
-
CSI 8.6rCSI 15.6%PRS 80.8%
-
CSI 8.8rCSI 22.6%PRS 84.1%
-
CSI 9.3rCSI 22.3%PRS 76.7%
-
CSI 9.9rCSI 15.9%PRS 80.2%
-
CSI 10.0rCSI 26.8%PRS 81.6%
-
CSI 10.0rCSI 36.0%PRS 71.3%
-
CSI 11.1rCSI 15.2%PRS 79.9%
-
CSI 11.7rCSI 15.1%PRS 74.4%
-
CSI 11.9rCSI 31.5%PRS 92.3%
-
CSI 12.1rCSI 45.6%PRS 73.6%
-
CSI 13.0rCSI 44.7%PRS 74.9%
-
CSI 14.5rCSI 29.5%PRS 69.1%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 506614188
Symbol: ANTR1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10947988
Title: Genes expressed in human tumor endothelium.
PubMed ID: 10947988
PubMed ID: 11700562
Title: Identification of the cellular receptor for anthrax toxin.
PubMed ID: 11700562
DOI: 10.1038/n35101999
PubMed ID: 22912819
Title: Broad expression analysis of human ANTXR1/TEM8 transcripts reveals differential expression and novel splizce variants.
PubMed ID: 22912819
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 12700348
Title: Human capillary morphogenesis protein 2 functions as an anthrax toxin receptor.
PubMed ID: 12700348
PubMed ID: 14759258
PubMed ID: 15777794
Title: TEM8 expression stimulates endothelial cell adhesion and migration by regulating cell-matrix interactions on collagen.
PubMed ID: 15777794
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 16762926
Title: Anthrax toxin receptor 1/tumor endothelium marker 8 mediates cell spreading by coupling extracellular ligands to the actin cytoskeleton.
PubMed ID: 16762926
PubMed ID: 19349973
Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.
PubMed ID: 19349973
DOI: 10.1038/nbt.1532
PubMed ID: 23602711
PubMed ID: 20585457
Title: The structure of tumor endothelial marker 8 (TEM8) extracellular domain and implications for its receptor function for recognizing anthrax toxin.
PubMed ID: 20585457
PubMed ID: 18931684
Title: Suppressed NFAT-dependent VEGFR1 expression and constitutive VEGFR2 signaling in infantile hemangioma.
PubMed ID: 18931684
DOI: 10.1038/nm.1877
Sequence Information:
- Length: 564
- Mass: 62789
- Checksum: B118A00AD5DF2233
- Sequence:
MATAERRALG IGFQWLSLAT LVLICAGQGG RREDGGPACY GGFDLYFILD KSGSVLHHWN EIYYFVEQLA HKFISPQLRM SFIVFSTRGT TLMKLTEDRE QIRQGLEELQ KVLPGGDTYM HEGFERASEQ IYYENRQGYR TASVIIALTD GELHEDLFFY SEREANRSRD LGAIVYCVGV KDFNETQLAR IADSKDHVFP VNDGFQALQG IIHSILKKSC IEILAAEPST ICAGESFQVV VRGNGFRHAR NVDRVLCSFK INDSVTLNEK PFSVEDTYLL CPAPILKEVG MKAALQVSMN DGLSFISSSV IITTTHCSDG SILAIALLIL FLLLALALLW WFWPLCCTVI IKEVPPPPAE ESEEEDDDGL PKKKWPTVDA SYYGGRGVGG IKRMEVRWGE KGSTEEGAKL EKAKNARVKM PEQEYEFPEP RNLNNNMRRP SSPRKWYSPI KGKLDALWVL LRKGYDRVSV MRPQPGDTGR CINFTRVKNN QPAKYPLNNA YHTSSPPPAP IYTPPPPAPH CPPPPPSAPT PPIPSPPSTL PPPPQAPPPN RAPPPSRPPP RPSV
Genular Protein ID: 1232958709
Symbol: Q96EC6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 97
- Mass: 10453
- Checksum: 14F475F0B170E71A
- Sequence:
FQVVVRGNGF RHARNVDSFL CSFKINDSVT LNEKPFSVED TYLLCPAPIL KEVGMKAALQ VSMNDGLSFI SSSVIITTTQ GSLHKIASGP TTAACME
Genular Protein ID: 1724925726
Symbol: Q53FL1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8125298
Title: Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.
PubMed ID: 8125298
PubMed ID: 9373149
Title: Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.
PubMed ID: 9373149
Sequence Information:
- Length: 317
- Mass: 35509
- Checksum: 7C8E0C94BB8FE100
- Sequence:
MATAERRALG IGFQWLSLAT LVLICAGQGG RREDGGPACY GGFDLYFILD KSGSVLHHWN EIYYFVEQLA HKFISPQLRM SFIVFSTRGT TLMKLTEDRE QIRQGLEELQ KVLPGGDTYM HEGFERASEQ IYYENRQGYR TASVIIALTD GELHEDLFFY SEREANRSRD LGAIVYCVGV KDFNETQLAR IADSKDHVFP VNDGFQALQG IIHSILKKSC IEILAAEPST ICAGESFQVV VRGNGFRHAR NVDRVLRSFK INDSVTLNEK PFSVEDTYLL CPAPILKEVG MKAALQVSMN DGLSFISSSV IITTTHC