Details for: RNU5E 4P

Gene ID: 100873829

Symbol: RNU5E 4P

Ensembl ID: ENSG00000201801

Description: RNA, U5E small nuclear 4, pseudogene

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 11.4829
    Cell Significance Index: -4.6700
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 1.9039
    Cell Significance Index: 22.4000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.5584
    Cell Significance Index: 16.0900
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.2337
    Cell Significance Index: 3.4500
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.1298
    Cell Significance Index: 2.0600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.0317
    Cell Significance Index: 3.6300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0215
    Cell Significance Index: 0.9800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0031
    Cell Significance Index: -5.7800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0038
    Cell Significance Index: -7.0000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0044
    Cell Significance Index: -0.8900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0045
    Cell Significance Index: -6.9300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0051
    Cell Significance Index: -6.9600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0071
    Cell Significance Index: -4.5300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0108
    Cell Significance Index: -0.3800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0122
    Cell Significance Index: -5.5200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0148
    Cell Significance Index: -0.7700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0158
    Cell Significance Index: -4.5400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0220
    Cell Significance Index: -3.7500
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0269
    Cell Significance Index: -0.6700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0296
    Cell Significance Index: -4.3000
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0310
    Cell Significance Index: -0.6700
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0329
    Cell Significance Index: -0.6600
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.0340
    Cell Significance Index: -0.6700
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0386
    Cell Significance Index: -0.8200
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.0415
    Cell Significance Index: -0.4300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0525
    Cell Significance Index: -3.3100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0577
    Cell Significance Index: -6.0100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0641
    Cell Significance Index: -3.9300
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0900
    Cell Significance Index: -4.6900
  • Cell Name: neuroplacodal cell (CL0000032)
    Fold Change: -0.0938
    Cell Significance Index: -1.1500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0952
    Cell Significance Index: -4.4400
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: -0.1109
    Cell Significance Index: -1.1800
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.1158
    Cell Significance Index: -1.5800
  • Cell Name: pancreatic stellate cell (CL0002410)
    Fold Change: -0.1270
    Cell Significance Index: -1.6000
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.1341
    Cell Significance Index: -1.8600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.1408
    Cell Significance Index: -3.0500
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: -0.1441
    Cell Significance Index: -2.0000
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.1481
    Cell Significance Index: -2.1300
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.1567
    Cell Significance Index: -3.2500
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: -0.1610
    Cell Significance Index: -2.0800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1695
    Cell Significance Index: -5.4300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.1754
    Cell Significance Index: -4.7000
  • Cell Name: thymocyte (CL0000893)
    Fold Change: -0.1951
    Cell Significance Index: -2.4700
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.2111
    Cell Significance Index: -3.5900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.2193
    Cell Significance Index: -5.9700
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.2242
    Cell Significance Index: -5.6000
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.2261
    Cell Significance Index: -5.7600
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.2346
    Cell Significance Index: -7.4200
  • Cell Name: memory B cell (CL0000787)
    Fold Change: -0.2434
    Cell Significance Index: -2.5900
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.2530
    Cell Significance Index: -5.5400
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: -0.2625
    Cell Significance Index: -3.6300
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: -0.2648
    Cell Significance Index: -2.3900
  • Cell Name: serous secreting cell (CL0000313)
    Fold Change: -0.2655
    Cell Significance Index: -2.3400
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: -0.2842
    Cell Significance Index: -3.6600
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.2866
    Cell Significance Index: -3.3700
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.2901
    Cell Significance Index: -4.1300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.2902
    Cell Significance Index: -6.1800
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.2931
    Cell Significance Index: -4.9300
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: -0.3012
    Cell Significance Index: -3.8700
  • Cell Name: retinal pigment epithelial cell (CL0002586)
    Fold Change: -0.3087
    Cell Significance Index: -3.3200
  • Cell Name: granulocyte (CL0000094)
    Fold Change: -0.3101
    Cell Significance Index: -3.7400
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: -0.3106
    Cell Significance Index: -5.3100
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: -0.3257
    Cell Significance Index: -4.5800
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.3404
    Cell Significance Index: -5.1000
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.3414
    Cell Significance Index: -5.8900
  • Cell Name: CD8-positive, alpha-beta thymocyte (CL0000811)
    Fold Change: -0.3501
    Cell Significance Index: -3.2400
  • Cell Name: plasma cell (CL0000786)
    Fold Change: -0.3553
    Cell Significance Index: -3.9700
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: -0.3570
    Cell Significance Index: -3.4800
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.3596
    Cell Significance Index: -4.4200
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.3612
    Cell Significance Index: -4.8000
  • Cell Name: neutrophil (CL0000775)
    Fold Change: -0.3618
    Cell Significance Index: -4.5200
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: -0.3699
    Cell Significance Index: -3.8400
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: -0.3719
    Cell Significance Index: -4.4200
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.3770
    Cell Significance Index: -4.9200
  • Cell Name: erythroblast (CL0000765)
    Fold Change: -0.3799
    Cell Significance Index: -4.5300
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.3824
    Cell Significance Index: -4.5500
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: -0.3830
    Cell Significance Index: -3.8400
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: -0.3887
    Cell Significance Index: -4.2200
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: -0.3904
    Cell Significance Index: -4.6000
  • Cell Name: mast cell (CL0000097)
    Fold Change: -0.3982
    Cell Significance Index: -5.2400
  • Cell Name: regulatory T cell (CL0000815)
    Fold Change: -0.4026
    Cell Significance Index: -4.6700
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: -0.4034
    Cell Significance Index: -5.5400
  • Cell Name: B cell (CL0000236)
    Fold Change: -0.4053
    Cell Significance Index: -4.7900
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: -0.4078
    Cell Significance Index: -5.1600
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: -0.4135
    Cell Significance Index: -3.8500
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: -0.4157
    Cell Significance Index: -4.2000
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: -0.4188
    Cell Significance Index: -3.6900
  • Cell Name: naive B cell (CL0000788)
    Fold Change: -0.4188
    Cell Significance Index: -4.4100
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: -0.4221
    Cell Significance Index: -5.2700
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: -0.4237
    Cell Significance Index: -5.5600
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.4243
    Cell Significance Index: -5.0100
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: -0.4282
    Cell Significance Index: -5.5900
  • Cell Name: pulmonary alveolar type 1 cell (CL0002062)
    Fold Change: -0.4282
    Cell Significance Index: -4.7000
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: -0.4290
    Cell Significance Index: -3.6200
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: -0.4297
    Cell Significance Index: -4.3600
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.4297
    Cell Significance Index: -5.6200
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: -0.4320
    Cell Significance Index: -4.5100
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: -0.4346
    Cell Significance Index: -5.2200
  • Cell Name: monocyte (CL0000576)
    Fold Change: -0.4371
    Cell Significance Index: -5.0300
  • Cell Name: macrophage (CL0000235)
    Fold Change: -0.4408
    Cell Significance Index: -4.5000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** RNU5E 4P is a type of pseudogene, which is a non-coding RNA that is derived from a non-coding gene. Pseudogenes are often found to be expressed in specific cell types and tissues, where they can play a regulatory role in gene expression. RNU5E 4P is specifically expressed in goblet cells, intestinal crypt stem cells, absorptive cells, and neoplastic cells, suggesting that it may play a role in maintaining the integrity of the intestinal epithelium. Notably, RNU5E 4P is also expressed in granulocytes, a type of white blood cell, which suggests that it may have a role in immune function. **Pathways and Functions:** The exact mechanisms by which RNU5E 4P regulates cellular processes are not yet fully understood. However, several pathways have been implicated in its function. One possible pathway involves the regulation of cell proliferation and differentiation through the modulation of gene expression. RNU5E 4P may also play a role in maintaining epithelial barrier function by regulating the expression of genes involved in tight junction formation and secretion. Additionally, RNU5E 4P may have a role in immune function, particularly in the context of granulocyte activation and differentiation. **Clinical Significance:** The clinical significance of RNU5E 4P is an area of ongoing research. While its exact role in human disease is not yet fully understood, several studies have implicated RNU5E 4P in the development of various intestinal and immune-related disorders. For example, altered expression of RNU5E 4P has been observed in patients with inflammatory bowel disease (IBD), such as Crohn's disease and ulcerative colitis. Additionally, RNU5E 4P has been implicated in the development of certain types of cancer, including colorectal cancer. Further research is needed to fully elucidate the clinical significance of RNU5E 4P and its potential as a biomarker or therapeutic target. In conclusion, RNU5E 4P is a pseudogene with far-reaching implications in immune and intestinal epithelial cells. Its widespread expression in various cell types and tissues suggests that it may play a regulatory role in maintaining cellular homeostasis. While its exact mechanisms of action are not yet fully understood, several pathways have been implicated in its function, including regulation of cell proliferation and differentiation, epithelial barrier function, and immune function. Further research is needed to fully elucidate the clinical significance of RNU5E 4P and its potential as a biomarker or therapeutic target.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.