Gene HSP90AB3P - ENSG00000183199 | NCBI Gene ID: 3327

Details for: HSP90AB3P

Gene ID: 3327

Symbol: HSP90AB3P

Ensembl ID: ENSG00000183199

Description: heat shock protein 90 alpha family class B member 3, pseudogene

Associated with

Atp-dependent protein folding chaperone
(GO:0140662)
Atp binding
(GO:0005524)
Atp hydrolysis activity
(GO:0016887)
Biological_process
(GO:0008150)
Cellular response to heat
(GO:0034605)
Cytosol
(GO:0005829)
Disordered domain specific binding
(GO:0097718)
Extracellular exosome
(GO:0070062)
Molecular_function
(GO:0003674)
Perinuclear region of cytoplasm
(GO:0048471)
Plasma membrane
(GO:0005886)
Protein-containing complex
(GO:0032991)
Protein folding
(GO:0006457)
Protein stabilization
(GO:0050821)
Unfolded protein binding
(GO:0051082)

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

Cell Name: type A enteroendocrine cell (CL0002067)
Fold Change: 1.57
Marker Score: 633
Cell Name: adventitial cell (CL0002503)
Fold Change: 0.81
Marker Score: 200
Cell Name: mesenchymal stem cell (CL0000134)
Fold Change: 0.79
Marker Score: 1223
Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
Fold Change: 0.55
Marker Score: 309
Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 0.44
Marker Score: 472
Cell Name: lung ciliated cell (CL1000271)
Fold Change: 0.34
Marker Score: 161
Cell Name: leukocyte (CL0000738)
Fold Change: 0.28
Marker Score: 158
Cell Name: malignant cell (CL0001064)
Fold Change: 0.25
Marker Score: 3293.5
Cell Name: hematopoietic stem cell (CL0000037)
Fold Change: 0.22
Marker Score: 118
Cell Name: thyroid follicular cell (CL0002258)
Fold Change: 0.2
Marker Score: 159.5
Cell Name: lung goblet cell (CL1000143)
Fold Change: 0.2
Marker Score: 57
Cell Name: CD8-positive, alpha-beta thymocyte (CL0000811)
Fold Change: 0.2
Marker Score: 108
Cell Name: innate lymphoid cell (CL0001065)
Fold Change: 0.19
Marker Score: 68
Cell Name: acinar cell (CL0000622)
Fold Change: 0.17
Marker Score: 120
Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.16
Marker Score: 43.5
Cell Name: bronchial smooth muscle cell (CL0002598)
Fold Change: 0.16
Marker Score: 45
Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.16
Marker Score: 232
Cell Name: epithelial cell of uterus (CL0002149)
Fold Change: 0.16
Marker Score: 36
Cell Name: type D enteroendocrine cell (CL0000502)
Fold Change: 0.16
Marker Score: 48
Cell Name: chondrocyte (CL0000138)
Fold Change: 0.15
Marker Score: 69
Cell Name: capillary endothelial cell (CL0002144)
Fold Change: 0.15
Marker Score: 162
Cell Name: epithelial cell (CL0000066)
Fold Change: 0.14
Marker Score: 227.5
Cell Name: tendon cell (CL0000388)
Fold Change: 0.14
Marker Score: 35
Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.13
Marker Score: 142
Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: 0.13
Marker Score: 237
Cell Name: hepatocyte (CL0000182)
Fold Change: 0.13
Marker Score: 87
Cell Name: muscle cell (CL0000187)
Fold Change: 0.13
Marker Score: 36
Cell Name: intestinal crypt stem cell (CL0002250)
Fold Change: 0.12
Marker Score: 47
Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
Fold Change: 0.11
Marker Score: 106
Cell Name: fibroblast of breast (CL4006000)
Fold Change: 0.11
Marker Score: 64
Cell Name: kidney loop of Henle epithelial cell (CL1000909)
Fold Change: 0.1
Marker Score: 65
Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.09
Marker Score: 211
Cell Name: fibroblast (CL0000057)
Fold Change: 0.09
Marker Score: 88
Cell Name: lung microvascular endothelial cell (CL2000016)
Fold Change: 0.09
Marker Score: 19
Cell Name: pericyte (CL0000669)
Fold Change: 0.09
Marker Score: 51
Cell Name: stromal cell (CL0000499)
Fold Change: 0.09
Marker Score: 101.5
Cell Name: memory B cell (CL0000787)
Fold Change: 0.09
Marker Score: 65.5
Cell Name: radial glial cell (CL0000681)
Fold Change: 0.08
Marker Score: 29
Cell Name: type I pneumocyte (CL0002062)
Fold Change: 0.07
Marker Score: 89.5
Cell Name: intestinal crypt stem cell of large intestine (CL0009016)
Fold Change: 0.07
Marker Score: 22
Cell Name: mesangial cell (CL0000650)
Fold Change: 0.07
Marker Score: 86
Cell Name: meningeal macrophage (CL0000879)
Fold Change: 0.07
Marker Score: 20
Cell Name: basal cell (CL0000646)
Fold Change: 0.07
Marker Score: 91
Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.07
Marker Score: 148
Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
Fold Change: 0.07
Marker Score: 59
Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.07
Marker Score: 17
Cell Name: endothelial cell of vascular tree (CL0002139)
Fold Change: 0.07
Marker Score: 98
Cell Name: lung neuroendocrine cell (CL1000223)
Fold Change: 0.07
Marker Score: 19
Cell Name: mast cell (CL0000097)
Fold Change: 0.07
Marker Score: 39
Cell Name: erythroid progenitor cell (CL0000038)
Fold Change: 0.07
Marker Score: 70
Cell Name: respiratory basal cell (CL0002633)
Fold Change: 0.07
Marker Score: 95
Cell Name: endocrine cell (CL0000163)
Fold Change: 0.06
Marker Score: 33.5
Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.06
Marker Score: 105
Cell Name: salivary gland cell (CL0009005)
Fold Change: 0.06
Marker Score: 20
Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.06
Marker Score: 385
Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
Fold Change: 0.06
Marker Score: 36
Cell Name: rod bipolar cell (CL0000751)
Fold Change: 0.06
Marker Score: 32
Cell Name: astrocyte (CL0000127)
Fold Change: 0.06
Marker Score: 53
Cell Name: mucus secreting cell (CL0000319)
Fold Change: 0.06
Marker Score: 15
Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 0.06
Marker Score: 16
Cell Name: keratocyte (CL0002363)
Fold Change: 0.06
Marker Score: 13
Cell Name: fast muscle cell (CL0000190)
Fold Change: 0.06
Marker Score: 17
Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 0.06
Marker Score: 19
Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.06
Marker Score: 58
Cell Name: granulocyte (CL0000094)
Fold Change: 0.06
Marker Score: 25
Cell Name: duct epithelial cell (CL0000068)
Fold Change: 0.06
Marker Score: 26
Cell Name: serous cell of epithelium of trachea (CL1000330)
Fold Change: 0.06
Marker Score: 20
Cell Name: type B pancreatic cell (CL0000169)
Fold Change: 0.06
Marker Score: 55
Cell Name: respiratory goblet cell (CL0002370)
Fold Change: 0.06
Marker Score: 16
Cell Name: intermediate monocyte (CL0002393)
Fold Change: 0.06
Marker Score: 19
Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 0.05
Marker Score: 17
Cell Name: embryonic stem cell (CL0002322)
Fold Change: 0.05
Marker Score: 17
Cell Name: endothelial cell of artery (CL1000413)
Fold Change: 0.05
Marker Score: 22
Cell Name: CD141-positive myeloid dendritic cell (CL0002394)
Fold Change: 0.05
Marker Score: 18
Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
Fold Change: 0.05
Marker Score: 44
Cell Name: neuroendocrine cell (CL0000165)
Fold Change: 0.05
Marker Score: 20
Cell Name: smooth muscle cell (CL0000192)
Fold Change: 0.05
Marker Score: 33.5
Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 0.05
Marker Score: 25
Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
Fold Change: 0.05
Marker Score: 11
Cell Name: vascular associated smooth muscle cell (CL0000359)
Fold Change: 0.05
Marker Score: 23
Cell Name: retinal blood vessel endothelial cell (CL0002585)
Fold Change: 0.05
Marker Score: 12
Cell Name: club cell (CL0000158)
Fold Change: 0.05
Marker Score: 58
Cell Name: pancreatic PP cell (CL0002275)
Fold Change: 0.05
Marker Score: 17
Cell Name: Unknown (CL0000003)
Fold Change: 0.05
Marker Score: 152
Cell Name: large intestine goblet cell (CL1000320)
Fold Change: 0.05
Marker Score: 13
Cell Name: plasma cell (CL0000786)
Fold Change: 0.05
Marker Score: 54
Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.05
Marker Score: 115.5
Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.05
Marker Score: 14
Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 0.05
Marker Score: 19
Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 0.05
Marker Score: 19
Cell Name: mature NK T cell (CL0000814)
Fold Change: 0.05
Marker Score: 21
Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.04
Marker Score: 84
Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.04
Marker Score: 17
Cell Name: retina horizontal cell (CL0000745)
Fold Change: 0.04
Marker Score: 42
Cell Name: renal intercalated cell (CL0005010)
Fold Change: 0.04
Marker Score: 23
Cell Name: type II pneumocyte (CL0002063)
Fold Change: 0.04
Marker Score: 269
Cell Name: ventricular cardiac muscle cell (CL2000046)
Fold Change: 0.04
Marker Score: 17
Cell Name: retinal pigment epithelial cell (CL0002586)
Fold Change: 0.04
Marker Score: 12
Cell Name: macrophage (CL0000235)
Fold Change: 0.04
Marker Score: 45
Cell Name: CD4-positive helper T cell (CL0000492)
Fold Change: 0.04
Marker Score: 44

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Other Information

Description

**Key characteristics:** * It is a member of the HSP90 family of heat shock proteins. * It is expressed in a variety of cell types, including type A enteroendocrine cells, adventitial cells, and lung ciliated cells. * It is a pseudogene, meaning it is not expressed in healthy individuals. * It is involved in protein folding and stability. * It is involved in the regulation of cell growth and differentiation. **Pathways and functions:** * It is involved in the folding and stability of other HSP90 proteins. * It is involved in the regulation of apoptosis (programmed cell death). * It is involved in the regulation of cell migration and invasion. * It is involved in the regulation of inflammation. **Clinical significance:** * Mutations in HSP90AB3P have been linked to a number of diseases, including cancer and neurodegenerative disorders. * HSP90AB3P is a potential target for cancer therapy. * It is a promising target for the treatment of neurodegenerative disorders, such as Alzheimer's disease. **Additional information:** * The gene is also known as HSP90B3P, HSP90B3, and TP73BP. * It is a highly conserved gene, with a similar gene found in other mammals. * It is a member of the HSP90 family of heat shock proteins, which are a large family of proteins that are involved in the folding and stability of other proteins.

Disclaimer: This summary is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.