Details for: NDUFV2P1

Gene ID: 4730

Symbol: NDUFV2P1

Ensembl ID: ENSG00000267809

Description: NADH:ubiquinone oxidoreductase core subunit V2 pseudogene 1

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 23.8865
    Cell Significance Index: -9.8400
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 3.1402
    Cell Significance Index: 40.4400
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 2.4041
    Cell Significance Index: 70.8100
  • Cell Name: granulocyte (CL0000094)
    Fold Change: 1.6754
    Cell Significance Index: 20.2100
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: 0.7984
    Cell Significance Index: 9.4900
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: 0.7454
    Cell Significance Index: 12.8500
  • Cell Name: naive regulatory T cell (CL0002677)
    Fold Change: 0.6213
    Cell Significance Index: 5.5900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.3438
    Cell Significance Index: 21.6700
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: 0.1340
    Cell Significance Index: 1.2100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0772
    Cell Significance Index: 15.5000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0230
    Cell Significance Index: 3.9200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0047
    Cell Significance Index: -8.8300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0059
    Cell Significance Index: -10.9600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0072
    Cell Significance Index: -11.0300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0083
    Cell Significance Index: -11.3200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0113
    Cell Significance Index: -7.1800
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0124
    Cell Significance Index: -0.6500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0160
    Cell Significance Index: -9.0100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0198
    Cell Significance Index: -8.9800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0249
    Cell Significance Index: -1.1600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0342
    Cell Significance Index: -3.9200
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: -0.0384
    Cell Significance Index: -0.3900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0442
    Cell Significance Index: -9.3100
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0491
    Cell Significance Index: -0.6700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0558
    Cell Significance Index: -8.1100
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: -0.0753
    Cell Significance Index: -0.8000
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.1082
    Cell Significance Index: -1.5000
  • Cell Name: T follicular helper cell (CL0002038)
    Fold Change: -0.1141
    Cell Significance Index: -1.2100
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.1197
    Cell Significance Index: -2.9900
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.1221
    Cell Significance Index: -1.4600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.1293
    Cell Significance Index: -5.8600
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.1449
    Cell Significance Index: -5.0800
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: -0.1495
    Cell Significance Index: -0.9400
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1507
    Cell Significance Index: -4.8000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1556
    Cell Significance Index: -5.1000
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.1656
    Cell Significance Index: -3.3300
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.1684
    Cell Significance Index: -3.3300
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1706
    Cell Significance Index: -3.6200
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.1851
    Cell Significance Index: -4.0000
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.1914
    Cell Significance Index: -4.7800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.1948
    Cell Significance Index: -5.2200
  • Cell Name: vascular associated smooth muscle cell (CL0000359)
    Fold Change: -0.2109
    Cell Significance Index: -2.2400
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.2119
    Cell Significance Index: -4.6400
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.2414
    Cell Significance Index: -8.8600
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.2459
    Cell Significance Index: -4.8400
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.2465
    Cell Significance Index: -4.9200
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.2480
    Cell Significance Index: -4.2500
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.2482
    Cell Significance Index: -5.1800
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.2497
    Cell Significance Index: -5.0800
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.2619
    Cell Significance Index: -7.1300
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.2860
    Cell Significance Index: -4.9500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2957
    Cell Significance Index: -9.4700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.3006
    Cell Significance Index: -8.6600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.3148
    Cell Significance Index: -11.0600
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.3161
    Cell Significance Index: -4.5000
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.3179
    Cell Significance Index: -8.1000
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: -0.3440
    Cell Significance Index: -5.8800
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.3579
    Cell Significance Index: -11.3200
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.3706
    Cell Significance Index: -5.8800
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: -0.3713
    Cell Significance Index: -5.4300
  • Cell Name: myofibroblast cell (CL0000186)
    Fold Change: -0.3883
    Cell Significance Index: -4.0700
  • Cell Name: pancreatic stellate cell (CL0002410)
    Fold Change: -0.3970
    Cell Significance Index: -5.0000
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.3974
    Cell Significance Index: -6.7500
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: -0.4188
    Cell Significance Index: -3.6900
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: -0.4489
    Cell Significance Index: -4.9100
  • Cell Name: thymocyte (CL0000893)
    Fold Change: -0.4519
    Cell Significance Index: -5.7100
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.4538
    Cell Significance Index: -6.7000
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: -0.4573
    Cell Significance Index: -4.6200
  • Cell Name: neuroplacodal cell (CL0000032)
    Fold Change: -0.4637
    Cell Significance Index: -5.7100
  • Cell Name: memory B cell (CL0000787)
    Fold Change: -0.4662
    Cell Significance Index: -4.9600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.4856
    Cell Significance Index: -10.5200
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.4887
    Cell Significance Index: -8.2200
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: -0.4924
    Cell Significance Index: -4.8000
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: -0.4930
    Cell Significance Index: -6.8400
  • Cell Name: muscle cell (CL0000187)
    Fold Change: -0.5018
    Cell Significance Index: -4.8000
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: -0.5183
    Cell Significance Index: -6.4700
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.5255
    Cell Significance Index: -10.9000
  • Cell Name: slow muscle cell (CL0000189)
    Fold Change: -0.5301
    Cell Significance Index: -7.9300
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.5370
    Cell Significance Index: -5.6700
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: -0.5402
    Cell Significance Index: -6.9400
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.5404
    Cell Significance Index: -6.3800
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: -0.5475
    Cell Significance Index: -7.6900
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: -0.5531
    Cell Significance Index: -5.1500
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: -0.5545
    Cell Significance Index: -5.3300
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: -0.5569
    Cell Significance Index: -9.0200
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: -0.5610
    Cell Significance Index: -6.0900
  • Cell Name: epithelial cell of lacrimal sac (CL1000436)
    Fold Change: -0.5614
    Cell Significance Index: -4.0400
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: -0.5618
    Cell Significance Index: -6.7900
  • Cell Name: pulmonary alveolar type 1 cell (CL0002062)
    Fold Change: -0.5694
    Cell Significance Index: -6.2500
  • Cell Name: regulatory T cell (CL0000815)
    Fold Change: -0.5724
    Cell Significance Index: -6.6400
  • Cell Name: intermediate monocyte (CL0002393)
    Fold Change: -0.5753
    Cell Significance Index: -5.3600
  • Cell Name: acinar cell (CL0000622)
    Fold Change: -0.5804
    Cell Significance Index: -7.2900
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: -0.5825
    Cell Significance Index: -7.3700
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: -0.5919
    Cell Significance Index: -7.2000
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: -0.5944
    Cell Significance Index: -7.8000
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: -0.5990
    Cell Significance Index: -6.7500
  • Cell Name: CD8-positive, alpha-beta thymocyte (CL0000811)
    Fold Change: -0.6008
    Cell Significance Index: -5.5600
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.6023
    Cell Significance Index: -9.0300
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: -0.6037
    Cell Significance Index: -8.2900
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.6048
    Cell Significance Index: -7.9100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** NDUFV2P1 is a pseudogene, which implies that it does not encode a functional protein. However, its expression in a wide range of cells suggests that it may be involved in regulating gene expression or participating in cellular processes. The pseudogene's expression profile, which includes embryonic stem cells, immune cells, and cells specific to the mammary gland and retina, indicates a potential role in development, immune function, and tissue homeostasis. **Pathways and Functions** The pathways and functions of NDUFV2P1 are not well understood, but several possibilities can be inferred based on its expression profile. One potential function of NDUFV2P1 is in the regulation of gene expression, particularly in embryonic development and tissue differentiation. The pseudogene's expression in immune cells suggests that it may play a role in immune function, possibly by regulating the expression of genes involved in immune responses. Another possibility is that NDUFV2P1 is involved in the regulation of cellular metabolism. The pseudogene's expression in cells involved in energy metabolism, such as granulocytes and fibroblasts, suggests that it may play a role in regulating energy production or storage. **Clinical Significance** The clinical significance of NDUFV2P1 is not well established, but several potential implications can be inferred based on its expression profile. The pseudogene's expression in immune cells and tissues suggests that it may be involved in the pathogenesis of immune-related disorders, such as autoimmune diseases or cancer. Furthermore, the pseudogene's expression in cells involved in energy metabolism suggests that it may be involved in the regulation of metabolic disorders, such as diabetes or obesity. Additionally, the pseudogene's expression in embryonic stem cells and cells involved in tissue development suggests that it may play a role in the development of congenital disorders or cancer. In conclusion, NDUFV2P1 is a pseudogene with a complex expression profile that suggests potential roles in regulating gene expression, cellular metabolism, and immune function. Further research is needed to fully understand the functional significance of this pseudogene and its potential implications for human health. **Recommendations for Future Research** 1. Investigate the functional significance of NDUFV2P1 using gene knockout or gene overexpression models. 2. Examine the expression profile of NDUFV2P1 in additional cell types and tissues to identify potential regulatory mechanisms. 3. Investigate the role of NDUFV2P1 in immune-related disorders, metabolic disorders, and congenital disorders. 4. Use bioinformatics tools to identify potential regulatory elements and transcription factor binding sites in the NDUFV2P1 gene. By addressing these research questions, we can gain a deeper understanding of the functional significance of NDUFV2P1 and its potential implications for human health.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.