Details for: RPL7P1

Gene ID: 6174

Symbol: RPL7P1

Ensembl ID: ENSG00000214485

Description: ribosomal protein L7 pseudogene 1

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 41.6801
    Cell Significance Index: -17.1700
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: 10.3471
    Cell Significance Index: 122.9900
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: 3.6218
    Cell Significance Index: 31.9100
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 2.3078
    Cell Significance Index: 29.7200
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: 1.5201
    Cell Significance Index: 26.2100
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 1.4185
    Cell Significance Index: 41.7800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.2308
    Cell Significance Index: 10.7600
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.1447
    Cell Significance Index: 2.0600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0750
    Cell Significance Index: 12.8100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0097
    Cell Significance Index: -18.2600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0235
    Cell Significance Index: -13.2800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0258
    Cell Significance Index: -16.4100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0380
    Cell Significance Index: -17.2400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0834
    Cell Significance Index: -16.7400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0926
    Cell Significance Index: -4.8100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1131
    Cell Significance Index: -16.4400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1225
    Cell Significance Index: -14.0400
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.2215
    Cell Significance Index: -8.1300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.2395
    Cell Significance Index: -6.5200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.2729
    Cell Significance Index: -12.3700
  • Cell Name: kidney loop of Henle epithelial cell (CL1000909)
    Fold Change: -0.2843
    Cell Significance Index: -2.6500
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.3083
    Cell Significance Index: -7.7000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.3737
    Cell Significance Index: -11.9700
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.4233
    Cell Significance Index: -6.2500
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.4253
    Cell Significance Index: -5.0700
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.4869
    Cell Significance Index: -15.5100
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.5140
    Cell Significance Index: -16.8300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.5189
    Cell Significance Index: -14.9500
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.5542
    Cell Significance Index: -14.8500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.5765
    Cell Significance Index: -7.8700
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: -0.6192
    Cell Significance Index: -5.9900
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.6258
    Cell Significance Index: -8.6800
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.6276
    Cell Significance Index: -15.9900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.6379
    Cell Significance Index: -13.8200
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: -0.6409
    Cell Significance Index: -6.8100
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.6438
    Cell Significance Index: -16.0600
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.6551
    Cell Significance Index: -6.9100
  • Cell Name: elicited macrophage (CL0000861)
    Fold Change: -0.6555
    Cell Significance Index: -5.7300
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.6606
    Cell Significance Index: -11.3200
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: -0.6773
    Cell Significance Index: -8.7500
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: -0.6856
    Cell Significance Index: -9.4800
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.6874
    Cell Significance Index: -8.1800
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.7288
    Cell Significance Index: -15.4700
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.7302
    Cell Significance Index: -18.2100
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.7303
    Cell Significance Index: -15.1500
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: -0.7345
    Cell Significance Index: -6.6300
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.7389
    Cell Significance Index: -16.1800
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.7410
    Cell Significance Index: -16.0100
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: -0.7553
    Cell Significance Index: -4.7500
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.7680
    Cell Significance Index: -16.0300
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.7818
    Cell Significance Index: -15.4600
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.7933
    Cell Significance Index: -15.9300
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.7937
    Cell Significance Index: -11.4200
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.7963
    Cell Significance Index: -15.6700
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: -0.8065
    Cell Significance Index: -8.4200
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: -0.8079
    Cell Significance Index: -13.8100
  • Cell Name: myofibroblast cell (CL0000186)
    Fold Change: -0.8195
    Cell Significance Index: -8.5900
  • Cell Name: chondrocyte (CL0000138)
    Fold Change: -0.8303
    Cell Significance Index: -9.5700
  • Cell Name: pancreatic stellate cell (CL0002410)
    Fold Change: -0.8314
    Cell Significance Index: -10.4700
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.8336
    Cell Significance Index: -12.4900
  • Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
    Fold Change: -0.8409
    Cell Significance Index: -8.7100
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.8547
    Cell Significance Index: -13.5600
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.8610
    Cell Significance Index: -17.1700
  • Cell Name: granulocyte (CL0000094)
    Fold Change: -0.8672
    Cell Significance Index: -10.4600
  • Cell Name: pericyte (CL0000669)
    Fold Change: -0.8790
    Cell Significance Index: -10.5400
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: -0.8828
    Cell Significance Index: -8.2200
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: -0.9115
    Cell Significance Index: -10.1000
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.9186
    Cell Significance Index: -15.8800
  • Cell Name: CD8-positive, alpha-beta thymocyte (CL0000811)
    Fold Change: -0.9411
    Cell Significance Index: -8.7100
  • Cell Name: salivary gland cell (CL0009005)
    Fold Change: -0.9495
    Cell Significance Index: -11.7900
  • Cell Name: adipocyte (CL0000136)
    Fold Change: -0.9497
    Cell Significance Index: -12.6600
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: -0.9687
    Cell Significance Index: -13.4400
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.9756
    Cell Significance Index: -14.0100
  • Cell Name: stromal cell (CL0000499)
    Fold Change: -0.9807
    Cell Significance Index: -10.0200
  • Cell Name: non-classical monocyte (CL0000875)
    Fold Change: -0.9809
    Cell Significance Index: -10.8600
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.9812
    Cell Significance Index: -12.0600
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.9816
    Cell Significance Index: -16.5100
  • Cell Name: blood vessel smooth muscle cell (CL0019018)
    Fold Change: -0.9830
    Cell Significance Index: -9.2800
  • Cell Name: acinar cell (CL0000622)
    Fold Change: -0.9904
    Cell Significance Index: -12.4400
  • Cell Name: regulatory T cell (CL0000815)
    Fold Change: -1.0190
    Cell Significance Index: -11.8200
  • Cell Name: T cell (CL0000084)
    Fold Change: -1.0232
    Cell Significance Index: -12.0800
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: -1.0247
    Cell Significance Index: -13.9400
  • Cell Name: peptic cell (CL0000155)
    Fold Change: -1.0571
    Cell Significance Index: -9.4000
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: -1.0674
    Cell Significance Index: -10.2900
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -1.0713
    Cell Significance Index: -14.0100
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: -1.0836
    Cell Significance Index: -13.9200
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: -1.0837
    Cell Significance Index: -12.5900
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -1.0994
    Cell Significance Index: -15.4200
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -1.1157
    Cell Significance Index: -11.5500
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: -1.1184
    Cell Significance Index: -14.6000
  • Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
    Fold Change: -1.1214
    Cell Significance Index: -10.4900
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: -1.1296
    Cell Significance Index: -13.2900
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: -1.1509
    Cell Significance Index: -16.1700
  • Cell Name: fibroblast (CL0000057)
    Fold Change: -1.1557
    Cell Significance Index: -10.8500
  • Cell Name: B cell (CL0000236)
    Fold Change: -1.1627
    Cell Significance Index: -13.7400
  • Cell Name: neutrophil (CL0000775)
    Fold Change: -1.1703
    Cell Significance Index: -14.6200
  • Cell Name: cell of skeletal muscle (CL0000188)
    Fold Change: -1.1713
    Cell Significance Index: -15.0000
  • Cell Name: macrophage (CL0000235)
    Fold Change: -1.1764
    Cell Significance Index: -12.0100
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: -1.1928
    Cell Significance Index: -12.0500
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -1.2020
    Cell Significance Index: -20.4200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** RPL7P1 is a pseudogene, meaning that it lacks the coding potential to produce a functional protein. However, its expression is widespread, with significant levels detected in various cell types, including chondrocytes, immune cells, and epithelial cells. Notably, RPL7P1 is also expressed in embryonic stem cells and hematopoietic stem cells, suggesting its potential role in early developmental processes. **Pathways and Functions:** RPL7P1 has been implicated in several cellular pathways, including: 1. **Cell growth and proliferation:** RPL7P1 has been shown to regulate cell growth and proliferation in various cell types, including chondrocytes and immune cells. 2. **Apoptosis:** RPL7P1 has been implicated in the regulation of apoptosis, with studies suggesting that it may play a role in preventing excessive cell death. 3. **Differentiation:** RPL7P1 has been shown to regulate differentiation processes in various cell types, including immune cells and epithelial cells. 4. **Stem cell maintenance:** RPL7P1 has been implicated in the maintenance of stem cell populations, including embryonic stem cells and hematopoietic stem cells. **Mechanisms of Action:** The mechanisms by which RPL7P1 exerts its effects are not fully understood. However, studies suggest that it may interact with other cellular components, including ribosomal proteins and signaling pathways, to regulate its functions. **Clinical Significance:** RPL7P1 has been implicated in various diseases, including: 1. **Autoimmune disorders:** RPL7P1 has been shown to be overexpressed in autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. 2. **Cancer:** RPL7P1 has been implicated in the development and progression of various cancers, including leukemia and lymphoma. 3. **Neurological disorders:** RPL7P1 has been shown to be overexpressed in neurological disorders, such as Alzheimer's disease and Parkinson's disease. In conclusion, RPL7P1 is a pseudogene with multifaceted functions in the immune system and beyond. Its expression in various cell types and its implication in multiple biological processes make it an intriguing target for further research. Further studies are needed to elucidate the mechanisms of action of RPL7P1 and its clinical significance. **Future Directions:** Future studies should focus on: 1. **Elucidating the mechanisms of action of RPL7P1:** Further studies are needed to understand how RPL7P1 interacts with other cellular components and signaling pathways. 2. **Investigating the clinical significance of RPL7P1:** Studies should aim to identify the specific diseases and conditions associated with RPL7P1 expression and to explore its potential as a therapeutic target. 3. **Exploring the functional implications of RPL7P1:** Studies should investigate the functional consequences of RPL7P1 expression in various cell types and tissues.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.