Details for: RN7SL34P

Gene ID: 106481824

Symbol: RN7SL34P

Ensembl ID: ENSG00000239868

Description: RNA, 7SL, cytoplasmic 34, pseudogene

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: myometrial cell (CL0002366)
    Fold Change: 0.2188
    Cell Significance Index: 2.5200
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: 0.1656
    Cell Significance Index: 2.1400
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 0.1627
    Cell Significance Index: 2.3800
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0859
    Cell Significance Index: 4.4600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0073
    Cell Significance Index: 0.4600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0028
    Cell Significance Index: -5.2300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0029
    Cell Significance Index: -0.5900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0031
    Cell Significance Index: -5.7700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0042
    Cell Significance Index: -6.4900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0049
    Cell Significance Index: -6.7100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0071
    Cell Significance Index: -4.5200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0092
    Cell Significance Index: -1.5700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0143
    Cell Significance Index: -6.4700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0154
    Cell Significance Index: -1.7700
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0202
    Cell Significance Index: -0.6600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0207
    Cell Significance Index: -0.6600
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0208
    Cell Significance Index: -0.5200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0281
    Cell Significance Index: -4.0800
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0286
    Cell Significance Index: -0.5800
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0305
    Cell Significance Index: -0.6600
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0311
    Cell Significance Index: -0.6600
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0321
    Cell Significance Index: -0.6400
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.0326
    Cell Significance Index: -0.6500
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.0382
    Cell Significance Index: -0.6600
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: -0.0526
    Cell Significance Index: -0.7300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0583
    Cell Significance Index: -6.0700
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: -0.0598
    Cell Significance Index: -0.6200
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: -0.0708
    Cell Significance Index: -0.7100
  • Cell Name: vascular associated smooth muscle cell (CL0000359)
    Fold Change: -0.1026
    Cell Significance Index: -1.0900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1285
    Cell Significance Index: -5.9900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.1422
    Cell Significance Index: -1.9400
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.1429
    Cell Significance Index: -2.1100
  • Cell Name: thymocyte (CL0000893)
    Fold Change: -0.1907
    Cell Significance Index: -2.4100
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.2004
    Cell Significance Index: -2.7800
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.2046
    Cell Significance Index: -7.5100
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: -0.2130
    Cell Significance Index: -2.3300
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.2242
    Cell Significance Index: -4.9100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.2397
    Cell Significance Index: -6.5300
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.2632
    Cell Significance Index: -8.3300
  • Cell Name: pericyte (CL0000669)
    Fold Change: -0.2660
    Cell Significance Index: -3.1900
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.2773
    Cell Significance Index: -4.4000
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.2854
    Cell Significance Index: -4.8000
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: -0.2884
    Cell Significance Index: -2.7900
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.2965
    Cell Significance Index: -5.0400
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: -0.3052
    Cell Significance Index: -3.9300
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.3271
    Cell Significance Index: -5.5100
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.3304
    Cell Significance Index: -6.4600
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: -0.3597
    Cell Significance Index: -4.9400
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: -0.3620
    Cell Significance Index: -4.6500
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.3840
    Cell Significance Index: -4.5700
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: -0.3913
    Cell Significance Index: -5.4100
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.3931
    Cell Significance Index: -4.9600
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.3938
    Cell Significance Index: -4.6300
  • Cell Name: salivary gland cell (CL0009005)
    Fold Change: -0.4019
    Cell Significance Index: -4.9900
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.4046
    Cell Significance Index: -5.2800
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.4064
    Cell Significance Index: -4.8500
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: -0.4077
    Cell Significance Index: -6.9700
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: -0.4236
    Cell Significance Index: -5.3600
  • Cell Name: capillary endothelial cell (CL0002144)
    Fold Change: -0.4260
    Cell Significance Index: -4.8400
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: -0.4286
    Cell Significance Index: -5.6000
  • Cell Name: memory B cell (CL0000787)
    Fold Change: -0.4361
    Cell Significance Index: -4.6400
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.4393
    Cell Significance Index: -5.4000
  • Cell Name: granule cell (CL0000120)
    Fold Change: -0.4409
    Cell Significance Index: -5.0200
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: -0.4416
    Cell Significance Index: -5.1300
  • Cell Name: stromal cell (CL0000499)
    Fold Change: -0.4453
    Cell Significance Index: -4.5500
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.4479
    Cell Significance Index: -4.8800
  • Cell Name: plasma cell (CL0000786)
    Fold Change: -0.4484
    Cell Significance Index: -5.0100
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: -0.4504
    Cell Significance Index: -4.5500
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.4564
    Cell Significance Index: -6.0700
  • Cell Name: pulmonary alveolar type 1 cell (CL0002062)
    Fold Change: -0.4582
    Cell Significance Index: -5.0300
  • Cell Name: non-classical monocyte (CL0000875)
    Fold Change: -0.4606
    Cell Significance Index: -5.1000
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.4608
    Cell Significance Index: -5.4400
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: -0.4629
    Cell Significance Index: -5.5600
  • Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
    Fold Change: -0.4695
    Cell Significance Index: -4.7300
  • Cell Name: mast cell (CL0000097)
    Fold Change: -0.4711
    Cell Significance Index: -6.2000
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: -0.4774
    Cell Significance Index: -5.3800
  • Cell Name: endothelial cell of artery (CL1000413)
    Fold Change: -0.4778
    Cell Significance Index: -5.0400
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: -0.4814
    Cell Significance Index: -6.0100
  • Cell Name: amacrine cell (CL0000561)
    Fold Change: -0.4823
    Cell Significance Index: -6.0400
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: -0.4840
    Cell Significance Index: -5.1500
  • Cell Name: B cell (CL0000236)
    Fold Change: -0.4857
    Cell Significance Index: -5.7400
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: -0.4874
    Cell Significance Index: -6.6300
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.4884
    Cell Significance Index: -5.5900
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.4887
    Cell Significance Index: -5.2400
  • Cell Name: macrophage (CL0000235)
    Fold Change: -0.4927
    Cell Significance Index: -5.0300
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: -0.4989
    Cell Significance Index: -6.0700
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: -0.5046
    Cell Significance Index: -5.7000
  • Cell Name: alveolar adventitial fibroblast (CL4028006)
    Fold Change: -0.5051
    Cell Significance Index: -5.6100
  • Cell Name: neutrophil (CL0000775)
    Fold Change: -0.5067
    Cell Significance Index: -6.3300
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: -0.5098
    Cell Significance Index: -5.6700
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: -0.5101
    Cell Significance Index: -6.0700
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: -0.5125
    Cell Significance Index: -5.2000
  • Cell Name: vein endothelial cell (CL0002543)
    Fold Change: -0.5156
    Cell Significance Index: -5.5900
  • Cell Name: retina horizontal cell (CL0000745)
    Fold Change: -0.5172
    Cell Significance Index: -6.4900
  • Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
    Fold Change: -0.5174
    Cell Significance Index: -4.8400
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -0.5181
    Cell Significance Index: -6.2800
  • Cell Name: monocyte (CL0000576)
    Fold Change: -0.5206
    Cell Significance Index: -5.9900
  • Cell Name: myofibroblast cell (CL0000186)
    Fold Change: -0.5257
    Cell Significance Index: -5.5100
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: -0.5273
    Cell Significance Index: -4.7600
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.5275
    Cell Significance Index: -5.0000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** RN7SL34P exhibits several distinctive characteristics that set it apart from other non-coding RNAs: 1. **Cytoplasmic localization**: RN7SL34P is primarily found in the cytoplasm, where it may interact with proteins or other RNAs to modulate cellular processes. 2. **Pseudogene status**: RN7SL34P lacks the ability to produce a functional protein, suggesting that its primary function may be regulatory, rather than coding for a protein. 3. **Wide tissue expression**: RN7SL34P is expressed in various cell types, including immune cells, stem cells, and epithelial cells, indicating its potential role in tissue homeostasis and immune system regulation. 4. **Abnormal expression in neoplastic cells**: RN7SL34P is overexpressed in neoplastic cells, suggesting its involvement in cancer development or progression. **Pathways and Functions:** While the exact mechanisms of RN7SL34P are unclear, several potential pathways and functions can be inferred based on its expression patterns and cellular localization: 1. **Regulation of immune responses**: RN7SL34P may modulate immune responses by influencing the activity of immune cells, such as B cells and plasma cells. 2. **Tissue homeostasis**: RN7SL34P may contribute to the maintenance of tissue homeostasis by regulating the differentiation and proliferation of stem cells and epithelial cells. 3. **Cellular stress response**: RN7SL34P may play a role in responding to cellular stress, such as DNA damage or oxidative stress, by regulating the expression of stress-related genes. 4. **Epigenetic regulation**: RN7SL34P may interact with epigenetic regulators to influence gene expression and chromatin structure. **Clinical Significance:** The identification of RN7SL34P as a pseudogene with significant immunological and clinical implications has far-reaching consequences: 1. **Cancer biomarker**: RN7SL34P may serve as a potential biomarker for cancer diagnosis or progression, particularly in tissues where it is overexpressed. 2. **Immunotherapy target**: RN7SL34P may be a viable target for immunotherapy, particularly in cancer treatment, where its expression can be exploited to modulate immune responses. 3. **Regulatory T cell modulation**: RN7SL34P may play a role in regulating the activity of regulatory T cells, which are essential for maintaining immune tolerance and preventing autoimmune disease. 4. **Stem cell biology**: RN7SL34P may contribute to our understanding of stem cell biology, particularly in the context of tissue homeostasis and regeneration. In conclusion, the RN7SL34P gene represents a fascinating area of research, with significant implications for our understanding of immune system regulation, tissue homeostasis, and cancer biology. Further investigation into its molecular mechanisms and functional significance is warranted to unlock its full potential as a therapeutic target or biomarker.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.