Details for: RNY1

Gene ID: 6084

Symbol: RNY1

Ensembl ID: ENSG00000201098

Description: RNA, Ro60-associated Y1

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 10.2152
    Cell Significance Index: -4.1500
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 4.3677
    Cell Significance Index: -4.1700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.3620
    Cell Significance Index: 16.4100
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.2949
    Cell Significance Index: 3.4700
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: 0.2910
    Cell Significance Index: 3.7600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.2728
    Cell Significance Index: 12.7200
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: 0.2513
    Cell Significance Index: 2.5200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.2308
    Cell Significance Index: 6.6500
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 0.1666
    Cell Significance Index: 2.3100
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: 0.1215
    Cell Significance Index: 1.2600
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: 0.0515
    Cell Significance Index: 0.4900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.0404
    Cell Significance Index: 1.1000
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.0403
    Cell Significance Index: 0.6400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0044
    Cell Significance Index: 0.7500
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.0040
    Cell Significance Index: 0.0600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0022
    Cell Significance Index: -4.2100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0026
    Cell Significance Index: -4.8100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0030
    Cell Significance Index: -0.8700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0032
    Cell Significance Index: -4.8800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0037
    Cell Significance Index: -5.0300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0052
    Cell Significance Index: -3.3200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0101
    Cell Significance Index: -4.6000
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.0122
    Cell Significance Index: -0.3600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0183
    Cell Significance Index: -3.6800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0227
    Cell Significance Index: -2.6000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0230
    Cell Significance Index: -3.3500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0322
    Cell Significance Index: -2.0300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0424
    Cell Significance Index: -2.2000
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: -0.0518
    Cell Significance Index: -0.5500
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0543
    Cell Significance Index: -3.3300
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0649
    Cell Significance Index: -3.3800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0659
    Cell Significance Index: -2.1100
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0677
    Cell Significance Index: -1.7400
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0851
    Cell Significance Index: -2.2800
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.0870
    Cell Significance Index: -1.8200
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: -0.0873
    Cell Significance Index: -0.8900
  • Cell Name: large intestine goblet cell (CL1000320)
    Fold Change: -0.0886
    Cell Significance Index: -0.9600
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0896
    Cell Significance Index: -3.1400
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.0899
    Cell Significance Index: -1.8300
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0931
    Cell Significance Index: -1.2700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.1032
    Cell Significance Index: -3.6300
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1045
    Cell Significance Index: -3.4200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.1052
    Cell Significance Index: -2.2800
  • Cell Name: intestinal crypt stem cell of large intestine (CL0009016)
    Fold Change: -0.1064
    Cell Significance Index: -0.9300
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.1160
    Cell Significance Index: -4.2600
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: -0.1172
    Cell Significance Index: -1.6200
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1247
    Cell Significance Index: -3.9700
  • Cell Name: serous secreting cell (CL0000313)
    Fold Change: -0.1250
    Cell Significance Index: -1.1000
  • Cell Name: pancreatic stellate cell (CL0002410)
    Fold Change: -0.1286
    Cell Significance Index: -1.6200
  • Cell Name: fast muscle cell (CL0000190)
    Fold Change: -0.1290
    Cell Significance Index: -1.6900
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: -0.1370
    Cell Significance Index: -1.4300
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.1374
    Cell Significance Index: -3.5000
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.1489
    Cell Significance Index: -2.9300
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.1499
    Cell Significance Index: -3.7400
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.1592
    Cell Significance Index: -5.0400
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.1690
    Cell Significance Index: -3.7000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.1798
    Cell Significance Index: -3.8300
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.1808
    Cell Significance Index: -3.7500
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.1819
    Cell Significance Index: -3.0900
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.1842
    Cell Significance Index: -4.6000
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1861
    Cell Significance Index: -3.9500
  • Cell Name: lung macrophage (CL1001603)
    Fold Change: -0.1904
    Cell Significance Index: -2.0800
  • Cell Name: bronchus fibroblast of lung (CL2000093)
    Fold Change: -0.1921
    Cell Significance Index: -2.0500
  • Cell Name: multi-ciliated epithelial cell (CL0005012)
    Fold Change: -0.1931
    Cell Significance Index: -2.0900
  • Cell Name: pulmonary artery endothelial cell (CL1001568)
    Fold Change: -0.1937
    Cell Significance Index: -2.0700
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.1944
    Cell Significance Index: -4.2000
  • Cell Name: mucus secreting cell (CL0000319)
    Fold Change: -0.1977
    Cell Significance Index: -2.0200
  • Cell Name: tracheobronchial smooth muscle cell (CL0019019)
    Fold Change: -0.2050
    Cell Significance Index: -2.1100
  • Cell Name: salivary gland cell (CL0009005)
    Fold Change: -0.2054
    Cell Significance Index: -2.5500
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: -0.2055
    Cell Significance Index: -2.6400
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: -0.2078
    Cell Significance Index: -2.1500
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.2087
    Cell Significance Index: -4.1900
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: -0.2089
    Cell Significance Index: -2.6900
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.2093
    Cell Significance Index: -2.9800
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.2109
    Cell Significance Index: -4.1700
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.2157
    Cell Significance Index: -3.7300
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.2158
    Cell Significance Index: -4.2200
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.2166
    Cell Significance Index: -4.3200
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.2176
    Cell Significance Index: -3.6600
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: -0.2205
    Cell Significance Index: -1.9900
  • Cell Name: respiratory hillock cell (CL4030023)
    Fold Change: -0.2212
    Cell Significance Index: -2.1000
  • Cell Name: vascular associated smooth muscle cell (CL0000359)
    Fold Change: -0.2345
    Cell Significance Index: -2.4900
  • Cell Name: brush cell of tracheobronchial tree (CL0002075)
    Fold Change: -0.2345
    Cell Significance Index: -2.1100
  • Cell Name: granulocyte (CL0000094)
    Fold Change: -0.2363
    Cell Significance Index: -2.8500
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: -0.2381
    Cell Significance Index: -4.0700
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: -0.2386
    Cell Significance Index: -2.4100
  • Cell Name: ionocyte (CL0005006)
    Fold Change: -0.2391
    Cell Significance Index: -2.5000
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.2404
    Cell Significance Index: -4.0500
  • Cell Name: tendon cell (CL0000388)
    Fold Change: -0.2405
    Cell Significance Index: -3.2700
  • Cell Name: memory B cell (CL0000787)
    Fold Change: -0.2416
    Cell Significance Index: -2.5700
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: -0.2439
    Cell Significance Index: -3.3500
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.2448
    Cell Significance Index: -2.8900
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.2466
    Cell Significance Index: -3.6400
  • Cell Name: DN4 thymocyte (CL0000808)
    Fold Change: -0.2469
    Cell Significance Index: -1.8600
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: -0.2554
    Cell Significance Index: -2.4900
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.2628
    Cell Significance Index: -3.0900
  • Cell Name: neuroplacodal cell (CL0000032)
    Fold Change: -0.2664
    Cell Significance Index: -3.2800
  • Cell Name: tracheobronchial serous cell (CL0019001)
    Fold Change: -0.2679
    Cell Significance Index: -2.0300
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: -0.2680
    Cell Significance Index: -3.0200
  • Cell Name: thymocyte (CL0000893)
    Fold Change: -0.2730
    Cell Significance Index: -3.4500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** RNY1 is a small non-coding RNA gene that has been identified through its association with the Ro60 protein, a component of the Ro ribonucleoprotein complex. This complex plays a crucial role in the regulation of RNA metabolism, particularly in the context of viral infections. The expression of RNY1 has been observed in various cell types, including those involved in the immune system, such as cardiac endothelial cells and intestinal epithelial cells. Furthermore, RNY1 has been found to be significantly expressed in neoplastic cells and abnormal cells, suggesting its potential involvement in cancer and other disease states. **Pathways and Functions:** The exact mechanisms by which RNY1 regulates cellular processes are not yet fully understood. However, research suggests that RNY1 may play a role in regulating RNA metabolism, particularly in the context of viral infections. RNY1 has been shown to interact with the Ro60 protein, which may influence the expression of genes involved in immune response and cell survival. Additionally, RNY1 may contribute to the regulation of cell proliferation and differentiation, particularly in the context of intestinal epithelial cells. One potential pathway through which RNY1 exerts its effects is through the regulation of microRNA (miRNA) expression. RNY1 has been shown to interact with miRNAs, influencing their expression and thereby modulating the regulation of target genes. This interaction may have significant implications for the regulation of cellular processes, including immune response and cell survival. **Clinical Significance:** The clinical significance of RNY1 is an area of ongoing research. However, its expression in neoplastic cells and abnormal cells suggests that RNY1 may play a role in the development and progression of various disease states, including cancer. Further studies are needed to fully elucidate the mechanisms by which RNY1 regulates cellular processes and to explore its potential as a therapeutic target. In the context of gastrointestinal diseases, RNY1 expression in intestinal epithelial cells suggests that this gene may play a role in the regulation of intestinal homeostasis and the development of disease states such as inflammatory bowel disease (IBD). Additionally, RNY1 expression in cardiac endothelial cells may have implications for cardiovascular disease. In summary, RNY1 is a gene of ongoing research with significant implications in the realm of immunology. Further studies are needed to fully elucidate its mechanisms of action and to explore its potential as a therapeutic target. As an expert immunologist, I believe that RNY1 is a gene that warrants further investigation, particularly in the context of various disease states, including cancer and gastrointestinal diseases.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.