Details for: SOX5
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
-
CSI 57.06rCSI 73.27%PRS 76.23
-
CSI 56.29rCSI 70.03%PRS 67.41
-
CSI 36.27rCSI 60.89%PRS 69.48
-
CSI 35.35rCSI 64.22%PRS 77.75
-
CSI 34.96rCSI 78.39%PRS 70.4
-
CSI 34.14rCSI 72.74%PRS 61.45
-
CSI 33.85rCSI 68.68%PRS 65.65
-
CSI 32.84rCSI 39.22%PRS 69.62
-
CSI 31.88rCSI 43.61%PRS 77.1
-
CSI 31.77rCSI 69.91%PRS 67.63
-
CSI 28.17rCSI 48.73%PRS 78.33
-
CSI 27.96rCSI 26.92%PRS 84.52
-
CSI 27.62rCSI 76.13%PRS 81.51
-
CSI 27.52rCSI 60.8%PRS 72.79
-
CSI 27.38rCSI 37.42%PRS 84.48
-
CSI 25.09rCSI 60.01%PRS 73.37
-
CSI 24.63rCSI 44.09%PRS 84.7
-
CSI 24.49rCSI 59.51%PRS 67.34
-
CSI 23.11rCSI 46.4%PRS 77.49
-
CSI 23.11rCSI 40.51%PRS 80.47
-
CSI 22.92rCSI 18.11%PRS 76.16
-
CSI 22.67rCSI 29.23%PRS 70.68
-
CSI 22.15rCSI 36.27%PRS 76.45
-
CSI 22.06rCSI 71.78%PRS 82.71
-
CSI 21.87rCSI 25.25%PRS 77.91
-
CSI 20.92rCSI 33.37%PRS 77.32
-
CSI 20.7rCSI 23.94%PRS 78.83
-
CSI 20.6rCSI 64.44%PRS 73.21
-
CSI 20.33rCSI 28.24%PRS 83.71
-
CSI 20.01rCSI 52.16%PRS 86.65
-
CSI 19.38rCSI 63.71%PRS 72.23
-
CSI 18.68rCSI 70.49%PRS 68.92
-
CSI 17.43rCSI 65.86%PRS 69.89
-
CSI 16.53rCSI 14.37%PRS 92.87
-
CSI 16.45rCSI 15.31%PRS 86.4
-
CSI 16.32rCSI 58.72%PRS 67.5
-
CSI 16rCSI 80.51%PRS 81.94
-
CSI 15.96rCSI 25.67%PRS 70.91
-
CSI 15.85rCSI 51.42%PRS 83.45
-
CSI 15.75rCSI 27.77%PRS 89.13
-
CSI 15.62rCSI 41.59%PRS 73.01
-
CSI 15.61rCSI 63.6%PRS 77.52
-
CSI 15.55rCSI 35.89%PRS 74.72
-
CSI 15.51rCSI 32.19%PRS 82.79
-
CSI 15.49rCSI 82.33%PRS 76.44
-
CSI 15.35rCSI 39.99%PRS 79.55
-
CSI 14.96rCSI 43.34%PRS 75.85
-
CSI 14.82rCSI 35.34%PRS 80.4
-
CSI 14.74rCSI 27.61%PRS 75.31
-
CSI 14.72rCSI 46%PRS 71.02
-
CSI 14.67rCSI 41.71%PRS 81.17
-
CSI 14.53rCSI 36.85%PRS 77.32
-
CSI 14.15rCSI 24.99%PRS 69.03
-
CSI 14.06rCSI 21.48%PRS 85.29
-
CSI 13.76rCSI 46.61%PRS 80.99
-
CSI 13.32rCSI 17.09%PRS 81.73
-
CSI 13.3rCSI 31.77%PRS 88.27
-
CSI 13.15rCSI 49.26%PRS 79.11
-
CSI 12.92rCSI 31.56%PRS 78.21
-
CSI 12.42rCSI 42.55%PRS 71.96
-
CSI 12.36rCSI 32.91%PRS 62.26
-
CSI 12.33rCSI 17.08%PRS 81.85
-
CSI 12.33rCSI 63.13%PRS 87.79
-
CSI 12.08rCSI 25.68%PRS 79.48
-
CSI 11.93rCSI 28%PRS 84.22
-
CSI 11.8rCSI 69.7%PRS 76.62
-
CSI 11.69rCSI 49.67%PRS 78.49
-
CSI 11.64rCSI 37.25%PRS 83.26
-
CSI 11.28rCSI 45.5%PRS 85.83
-
CSI 11.2rCSI 26.92%PRS 87.3
-
CSI 11.1rCSI 32.93%PRS 92.34
-
CSI 10.96rCSI 32.35%PRS 84.44
-
CSI 10.7rCSI 27.79%PRS 85.13
-
CSI 10.56rCSI 11.57%PRS 87.04
-
CSI 10.26rCSI 21.09%PRS 72.86
-
CSI 10.15rCSI 59.74%PRS 70.03
-
CSI 9.84rCSI 13.94%PRS 82.65
-
CSI 9.78rCSI 17.24%PRS 81.03
-
CSI 9.75rCSI 25.06%PRS 81.79
-
CSI 9.36rCSI 13.76%PRS 79.17
-
CSI 9.27rCSI 24.77%PRS 78.49
-
CSI 9.19rCSI 51.92%PRS 72.86
-
CSI 9.01rCSI 20.57%PRS 77.78
-
CSI 8.71rCSI 11.91%PRS 89.22
-
CSI 8.58rCSI 38.32%PRS 70.15
-
CSI 8.57rCSI 11.46%PRS 83.13
-
CSI 8.52rCSI 33.14%PRS 83.62
-
CSI 8.46rCSI 16.81%PRS 81.55
-
CSI 8.2rCSI 36.45%PRS 86.16
-
CSI 7.91rCSI 12.27%PRS 87.87
-
CSI 7.81rCSI 19.76%PRS 89.06
-
CSI 7.79rCSI 29.67%PRS 77.38
-
CSI 7.78rCSI 26.05%PRS 70.29
-
CSI 7.65rCSI 29.59%PRS 91.05
-
CSI 7.46rCSI 53.26%PRS 82.87
-
CSI 7.28rCSI 18.02%PRS 85.89
-
CSI 7.18rCSI 11.34%PRS 86.5
-
CSI 6.89rCSI 22.17%PRS 82.2
-
CSI 6.72rCSI 6.96%PRS 88.31
-
CSI 6.66rCSI 27.15%PRS 91.77
-
CSI 0.8rCSI 6.4%PRS 88.3%
-
CSI 0.8rCSI 6.3%PRS 85.9%
-
CSI 0.8rCSI 5.6%PRS 79.5%
-
CSI 1.3rCSI 3.5%PRS 90.0%
-
CSI 1.3rCSI 5.1%PRS 90.5%
-
CSI 1.3rCSI 11.2%PRS 75.0%
-
CSI 1.5rCSI 9.3%PRS 80.4%
-
CSI 1.5rCSI 11.3%PRS 74.6%
-
CSI 1.6rCSI 1.4%PRS 75.6%
-
CSI 1.7rCSI 2.1%PRS 83.7%
-
CSI 1.9rCSI 8.1%PRS 80.1%
-
CSI 2.3rCSI 13.9%PRS 88.0%
-
CSI 2.3rCSI 5.9%PRS 90.0%
-
CSI 2.3rCSI 5.1%PRS 85.2%
-
CSI 2.5rCSI 17.3%PRS 78.6%
-
CSI 2.6rCSI 11.5%PRS 74.1%
-
CSI 2.6rCSI 2.6%PRS 87.4%
-
CSI 2.7rCSI 14.0%PRS 86.2%
-
CSI 2.7rCSI 38.6%PRS 77.2%
-
CSI 2.9rCSI 4.6%PRS 79.4%
-
CSI 2.9rCSI 4.2%PRS 76.4%
-
CSI 2.9rCSI 33.5%PRS 73.8%
-
CSI 3.0rCSI 20.2%PRS 77.5%
-
CSI 3.2rCSI 4.4%PRS 91.7%
-
CSI 3.3rCSI 66.9%PRS 76.5%
-
CSI 3.3rCSI 67.3%PRS 75.7%
-
CSI 3.3rCSI 27.0%PRS 80.9%
-
CSI 3.8rCSI 35.2%PRS 84.5%
-
CSI 3.9rCSI 33.4%PRS 79.9%
-
CSI 4.0rCSI 5.9%PRS 85.0%
-
CSI 4.0rCSI 14.2%PRS 87.8%
-
CSI 4.1rCSI 10.5%PRS 79.2%
-
CSI 4.3rCSI 45.5%PRS 81.6%
-
CSI 4.3rCSI 20.1%PRS 93.9%
-
CSI 4.3rCSI 27.6%PRS 88.3%
-
CSI 4.3rCSI 11.4%PRS 90.5%
-
CSI 4.4rCSI 12.3%PRS 80.8%
-
CSI 4.5rCSI 28.3%PRS 78.1%
-
CSI 4.7rCSI 27.0%PRS 81.9%
-
CSI 5.0rCSI 9.4%PRS 91.7%
-
CSI 5.0rCSI 5.2%PRS 88.2%
-
CSI 5.0rCSI 24.1%PRS 85.6%
-
CSI 5.1rCSI 11.7%PRS 78.8%
-
CSI 5.2rCSI 9.4%PRS 79.7%
-
CSI 5.4rCSI 4.4%PRS 84.8%
-
CSI 5.5rCSI 13.1%PRS 85.2%
-
CSI 5.5rCSI 8.1%PRS 88.1%
-
CSI 5.6rCSI 4.4%PRS 88.7%
-
CSI 5.7rCSI 12.9%PRS 86.4%
-
CSI 5.9rCSI 61.2%PRS 79.1%
-
CSI 5.9rCSI 33.1%PRS 86.8%
-
CSI 6.0rCSI 19.2%PRS 85.9%
-
CSI 6.1rCSI 4.5%PRS 80.2%
-
CSI 6.1rCSI 29.2%PRS 81.4%
-
CSI 6.1rCSI 17.8%PRS 84.6%
-
CSI 6.2rCSI 9.9%PRS 76.6%
-
CSI 6.6rCSI 55.2%PRS 72.8%
-
CSI 6.6rCSI 25.7%PRS 65.4%
-
CSI 6.7rCSI 27.2%PRS 91.8%
-
CSI 6.7rCSI 7.0%PRS 88.3%
-
CSI 6.9rCSI 22.2%PRS 82.2%
-
CSI 7.2rCSI 11.3%PRS 86.5%
-
CSI 7.3rCSI 18.0%PRS 85.9%
-
CSI 7.5rCSI 53.3%PRS 82.9%
-
CSI 7.7rCSI 29.6%PRS 91.1%
-
CSI 7.8rCSI 26.1%PRS 70.3%
-
CSI 7.8rCSI 29.7%PRS 77.4%
-
CSI 7.8rCSI 19.8%PRS 89.1%
-
CSI 7.9rCSI 12.3%PRS 87.9%
-
CSI 8.2rCSI 36.5%PRS 86.2%
-
CSI 8.5rCSI 16.8%PRS 81.6%
-
CSI 8.5rCSI 33.1%PRS 83.6%
-
CSI 8.6rCSI 11.5%PRS 83.1%
-
CSI 8.6rCSI 38.3%PRS 70.2%
-
CSI 8.7rCSI 11.9%PRS 89.2%
-
CSI 9.0rCSI 20.6%PRS 77.8%
-
CSI 9.2rCSI 51.9%PRS 72.9%
-
CSI 9.3rCSI 24.8%PRS 78.5%
-
CSI 9.4rCSI 13.8%PRS 79.2%
-
CSI 9.8rCSI 25.1%PRS 81.8%
-
CSI 9.8rCSI 17.2%PRS 81.0%
-
CSI 9.8rCSI 13.9%PRS 82.7%
-
CSI 10.2rCSI 59.7%PRS 70.0%
-
CSI 10.3rCSI 21.1%PRS 72.9%
-
CSI 10.6rCSI 11.6%PRS 87.0%
-
CSI 10.7rCSI 27.8%PRS 85.1%
-
CSI 11.0rCSI 32.4%PRS 84.4%
-
CSI 11.1rCSI 32.9%PRS 92.3%
-
CSI 11.2rCSI 26.9%PRS 87.3%
-
CSI 11.3rCSI 45.5%PRS 85.8%
-
CSI 11.6rCSI 37.3%PRS 83.3%
-
CSI 11.7rCSI 49.7%PRS 78.5%
-
CSI 11.8rCSI 69.7%PRS 76.6%
-
CSI 11.9rCSI 28.0%PRS 84.2%
-
CSI 12.1rCSI 25.7%PRS 79.5%
-
CSI 12.3rCSI 63.1%PRS 87.8%
-
CSI 12.3rCSI 17.1%PRS 81.9%
-
CSI 12.4rCSI 32.9%PRS 62.3%
-
CSI 12.4rCSI 42.6%PRS 72.0%
-
CSI 12.9rCSI 31.6%PRS 78.2%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 2529468305
Symbol: SOX5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 12406576
Title: Identification and characterization of the human long form of Sox5 (L-SOX5) gene.
PubMed ID: 12406576
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16541075
Title: The finished DNA sequence of human chromosome 12.
PubMed ID: 16541075
DOI: 10.1038/nature04569
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8812465
Title: Cloning and characterization of SOX5, a new member of the human SOX gene family.
PubMed ID: 8812465
PubMed ID: 1614875
Title: A conserved family of genes related to the testis determining gene, SRY.
PubMed ID: 1614875
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 22290657
Title: Haploinsufficiency of SOX5 at 12p12.1 is associated with developmental delays with prominent language delay, behavior problems, and mild dysmorphic features.
PubMed ID: 22290657
DOI: 10.1002/humu.22037
PubMed ID: 23220431
Title: Haploinsufficiency of SOX5, a member of the SOX (SRY-related HMG-box) family of transcription factors is a cause of intellectual disability.
PubMed ID: 23220431
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 23498568
Title: Deletion 12p12 involving SOX5 in two children with developmental delay and dysmorphic features.
PubMed ID: 23498568
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 26111154
Title: Exome sequencing expands the mechanism of SOX5-associated intellectual disability: A case presentation with review of sox-related disorders.
PubMed ID: 26111154
DOI: 10.1002/ajmg.a.37221
PubMed ID: 21220648
Title: Resequencing of 29 candidate genes in patients with familial and sporadic amyotrophic lateral sclerosis.
PubMed ID: 21220648
Sequence Information:
- Length: 763
- Mass: 84026
- Checksum: 02B5B13429A59CAA
- Sequence:
MLTDPDLPQE FERMSSKRPA SPYGEADGEV AMVTSRQKVE EEESDGLPAF HLPLHVSFPN KPHSEEFQPV SLLTQETCGH RTPTSQHNTM EVDGNKVMSS FAPHNSSTSP QKAEEGGRQS GESLSSTALG TPERRKGSLA DVVDTLKQRK MEELIKNEPE ETPSIEKLLS KDWKDKLLAM GSGNFGEIKG TPESLAEKER QLMGMINQLT SLREQLLAAH DEQKKLAASQ IEKQRQQMEL AKQQQEQIAR QQQQLLQQQH KINLLQQQIQ VQGQLPPLMI PVFPPDQRTL AAAAQQGFLL PPGFSYKAGC SDPYPVQLIP TTMAAAAAAT PGLGPLQLQQ LYAAQLAAMQ VSPGGKLPGI PQGNLGAAVS PTSIHTDKST NSPPPKSKDE VAQPLNLSAK PKTSDGKSPT SPTSPHMPAL RINSGAGPLK ASVPAALASP SARVSTIGYL NDHDAVTKAI QEARQMKEQL RREQQVLDGK VAVVNSLGLN NCRTEKEKTT LESLTQQLAV KQNEEGKFSH AMMDFNLSGD SDGSAGVSES RIYRESRGRG SNEPHIKRPM NAFMVWAKDE RRKILQAFPD MHNSNISKIL GSRWKAMTNL EKQPYYEEQA RLSKQHLEKY PDYKYKPRPK RTCLVDGKKL RIGEYKAIMR NRRQEMRQYF NVGQQAQIPI ATAGVVYPGA IAMAGMPSPH LPSEHSSVSS SPEPGMPVIQ STYGVKGEEP HIKEEIQAED INGEIYDEYD EEEDDPDVDY GSDSENHIAG QAN
Genular Protein ID: 3947771197
Symbol: F5H0I3_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 16541075
Title: The finished DNA sequence of human chromosome 12.
PubMed ID: 16541075
DOI: 10.1038/nature04569
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 728
- Mass: 80077
- Checksum: C465EFBA8009AC73
- Sequence:
MLTDPDLPQE FERMSSKRPA SPYGEADGEV AMVTSRQKVE EEESDGLPAF HLPLHEVDGN KVMSSFAPHN SSTSPQKAEE GGRQSGESLS STALGTPERR KGSLADVVDT LKQRKMEELI KNEPEETPSI EKLLSKDWKD KLLAMGSGNF GEIKGTPESL AEKERQLMGM INQLTSLREQ LLAAHDEQKK LAASQIEKQR QQMELAKQQQ EQIARQQQQL LQQQHKINLL QQQIQVQGQL PPLMIPVFPP DQRTLAAAAQ QGFLLPPGFS YKAGCSDPYP VQLIPTTMAA AAAATPGLGP LQLQQLYAAQ LAAMQVSPGG KLPGIPQGNL GAAVSPTSIH TDKSTNSPPP KSKDEVAQPL NLSAKPKTSD GKSPTSPTSP HMPALRINSG AGPLKASVPA ALASPSARVS TIGYLNDHDA VTKAIQEARQ MKEQLRREQQ VLDGKVAVVN SLGLNNCRTE KEKTTLESLT QQLAVKQNEE GKFSHAMMDF NLSGDSDGSA GVSESRIYRE SRGRGSNEPH IKRPMNAFMV WAKDERRKIL QAFPDMHNSN ISKILGSRWK AMTNLEKQPY YEEQARLSKQ HLEKYPDYKY KPRPKRTCLV DGKKLRIGEY KAIMRNRRQE MRQYFNVGQQ AQIPIATAGV VYPGAIAMAG MPSPHLPSEH SSVSSSPEPG MPVIQSTYGV KGEEPHIKEE IQAEDINGEI YDEYDEEEDD PDVDYGSDSE NHIAGQAN
Genular Protein ID: 1234096668
Symbol: T2CYZ2_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 24945754
Title: High Levels of SOX5 Decrease Proliferative Capacity of Human B Cells, but Permit Plasmablast Differentiation.
PubMed ID: 24945754
Sequence Information:
- Length: 750
- Mass: 82453
- Checksum: F8152F0BD72E6734
- Sequence:
MSSKRPASPY GEADGEVAMV TSRQKVEEEE SDGLPAFHLP LHVSFPNKPH SEEFQPVSLL TQETCGHRTP TSQHNTMEVD GNKVMSSFAP HNSSTSPQKA EEGGRQSGES LSSTALGTPE RRKGSLADVV DTLKQRKMEE LIKNEPEETP SIEKLLSKDW KDKLLAMGSG NFGEIKGTPE SLAEKERQLM GMINQLTSLR EQLLAAHDEQ KKLAASQIEK QRQQMELAKQ QQEQIARQQQ QLLQQQHKIN LLQQQIQVQG QLPPLMIPVF PPDQRTLAAA AQQGFLLPPG FSYKAGCSDP YPVQLIPTTM AAAAAATPGL GPLQLQQLYA AQLAAMQVSP GGKLPGIPQG NLGAAVSPTS IHTDKSTNSP PPKSKDEVAQ PLNLSAKPKT SDGKSPTSPT SPHMPALRIN SGAGPLKASV PAALASPSAR VSTIGYLNDH DAVTKAIQEA RQMKEQLRRE QQVLDGKVAV VNSLGLNNCR TEKEKTTLES LTQQLAVKQN EEGKFSHAMM DFNLSGDSDG SAGVSESRIY RESRGRGSNE PHIKRPMNAF MVWAKDERRK ILQAFPDMHN SNISKILGSR WKAMTNLEKQ PYYEEQARLS KQHLEKYPDY KYKPRPKRTC LVDGKKLRIG EYKAIMRNRR QEMRQYFNVG QQAQIPIATA GVVYPGAIAM AGMPSPHLPS EHSSVSSSPE PGMPVIQSTY GVKGEEPHIK EEIQAEDING EIYDEYDEEE DDPDVDYGSD SENHIAGQAN