Details for: OR7E28P

Gene ID: 26645

Symbol: OR7E28P

Ensembl ID: ENSG00000251491

Description: olfactory receptor family 7 subfamily E member 28 pseudogene

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 9.6267
    Cell Significance Index: 240.4400
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: 0.1517
    Cell Significance Index: 1.9600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0745
    Cell Significance Index: 12.7200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0646
    Cell Significance Index: 3.3600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.0229
    Cell Significance Index: 3.3300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0035
    Cell Significance Index: 6.6200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0031
    Cell Significance Index: -5.6600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0038
    Cell Significance Index: -2.1500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0039
    Cell Significance Index: -2.4700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0040
    Cell Significance Index: -6.1600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0062
    Cell Significance Index: -8.4800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0074
    Cell Significance Index: -0.8500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0082
    Cell Significance Index: -1.6400
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: -0.0085
    Cell Significance Index: -0.1200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0130
    Cell Significance Index: -5.9000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0500
    Cell Significance Index: -3.1500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0597
    Cell Significance Index: -0.8200
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0606
    Cell Significance Index: -1.9300
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0661
    Cell Significance Index: -1.6500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0762
    Cell Significance Index: -7.9300
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0763
    Cell Significance Index: -1.6500
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0807
    Cell Significance Index: -1.1900
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.0813
    Cell Significance Index: -1.2900
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.0821
    Cell Significance Index: -1.4200
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0895
    Cell Significance Index: -1.8000
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0899
    Cell Significance Index: -1.9100
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.0914
    Cell Significance Index: -1.2700
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: -0.1170
    Cell Significance Index: -1.1400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1268
    Cell Significance Index: -5.9100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.1294
    Cell Significance Index: -5.8600
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: -0.1325
    Cell Significance Index: -1.4500
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: -0.1383
    Cell Significance Index: -1.6800
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.1454
    Cell Significance Index: -2.0700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.2541
    Cell Significance Index: -6.8100
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: -0.2675
    Cell Significance Index: -3.7000
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.2996
    Cell Significance Index: -3.1600
  • Cell Name: stromal cell (CL0000499)
    Fold Change: -0.3279
    Cell Significance Index: -3.3500
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: -0.3366
    Cell Significance Index: -2.5900
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: -0.3383
    Cell Significance Index: -3.9300
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.3599
    Cell Significance Index: -7.8800
  • Cell Name: non-classical monocyte (CL0000875)
    Fold Change: -0.3791
    Cell Significance Index: -4.2000
  • Cell Name: acinar cell (CL0000622)
    Fold Change: -0.4363
    Cell Significance Index: -5.4800
  • Cell Name: mast cell (CL0000097)
    Fold Change: -0.4453
    Cell Significance Index: -5.8600
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: -0.4511
    Cell Significance Index: -4.6500
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.4741
    Cell Significance Index: -6.3000
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: -0.4917
    Cell Significance Index: -5.7500
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.5168
    Cell Significance Index: -6.1500
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.5251
    Cell Significance Index: -16.6100
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: -0.5386
    Cell Significance Index: -6.5100
  • Cell Name: stem cell (CL0000034)
    Fold Change: -0.5435
    Cell Significance Index: -3.9500
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: -0.5631
    Cell Significance Index: -7.1300
  • Cell Name: retinal pigment epithelial cell (CL0002586)
    Fold Change: -0.5755
    Cell Significance Index: -6.1900
  • Cell Name: myoepithelial cell (CL0000185)
    Fold Change: -0.5769
    Cell Significance Index: -6.5400
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: -0.5770
    Cell Significance Index: -7.8500
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.5780
    Cell Significance Index: -9.8200
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: -0.5877
    Cell Significance Index: -6.9300
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: -0.5907
    Cell Significance Index: -7.6100
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.6000
    Cell Significance Index: -7.8300
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: -0.6160
    Cell Significance Index: -7.6900
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: -0.6189
    Cell Significance Index: -6.9300
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.6268
    Cell Significance Index: -7.9100
  • Cell Name: retina horizontal cell (CL0000745)
    Fold Change: -0.6312
    Cell Significance Index: -7.9200
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: -0.6314
    Cell Significance Index: -6.9000
  • Cell Name: amacrine cell (CL0000561)
    Fold Change: -0.6324
    Cell Significance Index: -7.9200
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.6501
    Cell Significance Index: -7.7500
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: -0.6602
    Cell Significance Index: -7.9300
  • Cell Name: macrophage (CL0000235)
    Fold Change: -0.6788
    Cell Significance Index: -6.9300
  • Cell Name: neuroblast (sensu Nematoda and Protostomia) (CL0000338)
    Fold Change: -0.6798
    Cell Significance Index: -6.1800
  • Cell Name: glial cell (CL0000125)
    Fold Change: -0.6804
    Cell Significance Index: -7.4600
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.6885
    Cell Significance Index: -7.8800
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: -0.6908
    Cell Significance Index: -7.9200
  • Cell Name: granule cell (CL0000120)
    Fold Change: -0.6948
    Cell Significance Index: -7.9100
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: -0.7028
    Cell Significance Index: -7.9400
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.7206
    Cell Significance Index: -7.4600
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.7251
    Cell Significance Index: -7.9000
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.7331
    Cell Significance Index: -7.8600
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: -0.7454
    Cell Significance Index: -7.0800
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: -0.7626
    Cell Significance Index: -6.9500
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.8113
    Cell Significance Index: -7.6900
  • Cell Name: melanocyte (CL0000148)
    Fold Change: -0.8143
    Cell Significance Index: -7.6300
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: -0.8187
    Cell Significance Index: -7.9200
  • Cell Name: fibroblast (CL0000057)
    Fold Change: -0.8340
    Cell Significance Index: -7.8300
  • Cell Name: OFF-bipolar cell (CL0000750)
    Fold Change: -0.9008
    Cell Significance Index: -7.9400
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: -0.9039
    Cell Significance Index: -6.9100
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.9050
    Cell Significance Index: -7.4700
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: -0.9130
    Cell Significance Index: -5.9400
  • Cell Name: kidney interstitial cell (CL1000500)
    Fold Change: -0.9270
    Cell Significance Index: -6.9400
  • Cell Name: glioblast (CL0000030)
    Fold Change: -0.9443
    Cell Significance Index: -5.9300
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: -0.9781
    Cell Significance Index: -14.8800
  • Cell Name: renal intercalated cell (CL0005010)
    Fold Change: -0.9821
    Cell Significance Index: -7.8400
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: -1.0010
    Cell Significance Index: -5.9400
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: -1.0254
    Cell Significance Index: -10.9000
  • Cell Name: club cell (CL0000158)
    Fold Change: -1.1332
    Cell Significance Index: -12.3500
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: -1.3120
    Cell Significance Index: -13.5800
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: -1.3648
    Cell Significance Index: -11.0500
  • Cell Name: blood vessel endothelial cell (CL0000071)
    Fold Change: -1.3807
    Cell Significance Index: -15.0000
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: -1.5449
    Cell Significance Index: -14.8300
  • Cell Name: memory B cell (CL0000787)
    Fold Change: -1.6997
    Cell Significance Index: -18.0800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** OR7E28P is a pseudogene, meaning it lacks a functional coding sequence and does not produce a protein. However, pseudogenes can still influence gene expression and regulation, and in some cases, may contribute to the evolution of new gene functions. The OR7E28P gene is expressed in multiple cell types, including those found in the skin, eye, and lens, suggesting a role in tissue development and maintenance. Its expression in secondary lens fiber cells is particularly intriguing, as it may be involved in the regulation of lens transparency and refractive properties. **Pathways and Functions:** While the OR7E28P gene lacks a functional coding sequence, it is possible that its expression is influenced by regulatory elements that interact with nearby genes or other regulatory networks. The gene's expression in various cell types suggests that it may be involved in the regulation of cellular processes such as proliferation, differentiation, and survival. For example, its expression in keratinocytes and epithelial cells may be related to the maintenance of skin and epithelial barrier function. In the context of the lens, OR7E28P may play a role in regulating lens fiber cell differentiation and transparency. **Clinical Significance:** The OR7E28P gene's expression in lens fiber cells raises questions about its potential involvement in ophthalmological disorders, such as cataracts or age-related macular degeneration. Further studies are needed to determine whether OR7E28P is involved in the pathogenesis of these diseases. Additionally, the gene's expression in other cell types suggests that it may be involved in the regulation of immune responses, particularly in the context of ocular and skin infections. Investigating the immunological implications of OR7E28P may provide insights into novel therapeutic strategies for the treatment of immune-related disorders. In conclusion, the OR7E28P gene, despite its pseudogene status, has garnered attention for its potential immunological significance and clinical implications. Further research is needed to elucidate the gene's functions and regulatory mechanisms, with a focus on its potential involvement in ophthalmological disorders and immune-related diseases.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.