Details for: SNORA69

Gene ID: 26779

Symbol: SNORA69

Ensembl ID: ENSG00000206622

Description: small nucleolar RNA, H/ACA box 69

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: 0.1341
    Cell Significance Index: 1.7300
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.0296
    Cell Significance Index: 0.4700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.0283
    Cell Significance Index: 3.2400
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.0213
    Cell Significance Index: 0.2900
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.0088
    Cell Significance Index: 0.1300
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.0028
    Cell Significance Index: -0.0400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0042
    Cell Significance Index: -0.8500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0044
    Cell Significance Index: -0.7500
  • Cell Name: granulocyte (CL0000094)
    Fold Change: -0.0049
    Cell Significance Index: -0.0600
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: -0.0117
    Cell Significance Index: -0.1100
  • Cell Name: stromal cell (CL0000499)
    Fold Change: -0.0129
    Cell Significance Index: -0.1300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0196
    Cell Significance Index: -1.0200
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.0248
    Cell Significance Index: -0.6200
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.0281
    Cell Significance Index: -0.3900
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0283
    Cell Significance Index: -0.9000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0285
    Cell Significance Index: -0.8200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0357
    Cell Significance Index: -1.8600
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: -0.0410
    Cell Significance Index: -0.4800
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0425
    Cell Significance Index: -0.8500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0458
    Cell Significance Index: -2.0700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0569
    Cell Significance Index: -1.5500
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.0598
    Cell Significance Index: -0.7800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0682
    Cell Significance Index: -2.4000
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: -0.0738
    Cell Significance Index: -0.9500
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.0824
    Cell Significance Index: -1.2400
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: -0.0966
    Cell Significance Index: -1.2400
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: -0.1006
    Cell Significance Index: -1.7200
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: -0.1015
    Cell Significance Index: -1.0300
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.1017
    Cell Significance Index: -2.1100
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.1025
    Cell Significance Index: -1.2200
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: -0.1097
    Cell Significance Index: -1.1400
  • Cell Name: vascular associated smooth muscle cell (CL0000359)
    Fold Change: -0.1106
    Cell Significance Index: -1.1700
  • Cell Name: club cell (CL0000158)
    Fold Change: -0.1111
    Cell Significance Index: -1.2100
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: -0.1201
    Cell Significance Index: -1.2000
  • Cell Name: fibroblast (CL0000057)
    Fold Change: -0.1204
    Cell Significance Index: -1.1300
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: -0.1223
    Cell Significance Index: -1.6800
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: -0.1394
    Cell Significance Index: -1.6200
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.1437
    Cell Significance Index: -2.4400
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: -0.1444
    Cell Significance Index: -1.4100
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: -0.1489
    Cell Significance Index: -1.3400
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.1538
    Cell Significance Index: -2.5900
  • Cell Name: naive B cell (CL0000788)
    Fold Change: -0.1574
    Cell Significance Index: -1.6600
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: -0.1649
    Cell Significance Index: -1.9600
  • Cell Name: neutrophil (CL0000775)
    Fold Change: -0.1665
    Cell Significance Index: -2.0800
  • Cell Name: plasma cell (CL0000786)
    Fold Change: -0.1665
    Cell Significance Index: -1.8600
  • Cell Name: B cell (CL0000236)
    Fold Change: -0.1667
    Cell Significance Index: -1.9700
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.1692
    Cell Significance Index: -2.0800
  • Cell Name: non-classical monocyte (CL0000875)
    Fold Change: -0.1698
    Cell Significance Index: -1.8800
  • Cell Name: mucosal invariant T cell (CL0000940)
    Fold Change: -0.1712
    Cell Significance Index: -1.9700
  • Cell Name: medium spiny neuron (CL1001474)
    Fold Change: -0.1719
    Cell Significance Index: -2.3200
  • Cell Name: pulmonary alveolar type 1 cell (CL0002062)
    Fold Change: -0.1731
    Cell Significance Index: -1.9000
  • Cell Name: memory B cell (CL0000787)
    Fold Change: -0.1739
    Cell Significance Index: -1.8500
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: -0.1751
    Cell Significance Index: -2.1300
  • Cell Name: capillary endothelial cell (CL0002144)
    Fold Change: -0.1761
    Cell Significance Index: -2.0000
  • Cell Name: macrophage (CL0000235)
    Fold Change: -0.1763
    Cell Significance Index: -1.8000
  • Cell Name: myofibroblast cell (CL0000186)
    Fold Change: -0.1784
    Cell Significance Index: -1.8700
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: -0.1793
    Cell Significance Index: -1.8500
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.1846
    Cell Significance Index: -2.3300
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.1854
    Cell Significance Index: -2.1800
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: -0.1872
    Cell Significance Index: -2.1100
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: -0.1873
    Cell Significance Index: -1.9600
  • Cell Name: endothelial cell of artery (CL1000413)
    Fold Change: -0.1879
    Cell Significance Index: -1.9800
  • Cell Name: monocyte (CL0000576)
    Fold Change: -0.1921
    Cell Significance Index: -2.2100
  • Cell Name: vein endothelial cell (CL0002543)
    Fold Change: -0.1937
    Cell Significance Index: -2.1000
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.1954
    Cell Significance Index: -2.5500
  • Cell Name: large intestine goblet cell (CL1000320)
    Fold Change: -0.1991
    Cell Significance Index: -2.1600
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.2024
    Cell Significance Index: -2.1700
  • Cell Name: respiratory basal cell (CL0002633)
    Fold Change: -0.2037
    Cell Significance Index: -2.0100
  • Cell Name: amacrine cell (CL0000561)
    Fold Change: -0.2068
    Cell Significance Index: -2.5900
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.2086
    Cell Significance Index: -2.2000
  • Cell Name: retina horizontal cell (CL0000745)
    Fold Change: -0.2088
    Cell Significance Index: -2.6200
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.2122
    Cell Significance Index: -2.5300
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.2143
    Cell Significance Index: -2.5300
  • Cell Name: lung ciliated cell (CL1000271)
    Fold Change: -0.2162
    Cell Significance Index: -2.1200
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -0.2174
    Cell Significance Index: -2.6400
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.2190
    Cell Significance Index: -2.9100
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: -0.2209
    Cell Significance Index: -2.1000
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.2228
    Cell Significance Index: -2.5500
  • Cell Name: intermediate monocyte (CL0002393)
    Fold Change: -0.2243
    Cell Significance Index: -2.0900
  • Cell Name: effector memory CD4-positive, alpha-beta T cell (CL0000905)
    Fold Change: -0.2249
    Cell Significance Index: -2.0800
  • Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
    Fold Change: -0.2304
    Cell Significance Index: -2.1600
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.2322
    Cell Significance Index: -2.5300
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: -0.2324
    Cell Significance Index: -2.6300
  • Cell Name: pulmonary alveolar type 2 cell (CL0002063)
    Fold Change: -0.2345
    Cell Significance Index: -1.9400
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: -0.2372
    Cell Significance Index: -2.0900
  • Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell (CL0000895)
    Fold Change: -0.2411
    Cell Significance Index: -2.0800
  • Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
    Fold Change: -0.2442
    Cell Significance Index: -2.3200
  • Cell Name: elicited macrophage (CL0000861)
    Fold Change: -0.2448
    Cell Significance Index: -2.1400
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: -0.2553
    Cell Significance Index: -2.7200
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: -0.2554
    Cell Significance Index: -2.5200
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: -0.2580
    Cell Significance Index: -2.0900
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: -0.2588
    Cell Significance Index: -2.4100
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: -0.2612
    Cell Significance Index: -2.6500
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: -0.2629
    Cell Significance Index: -2.4400
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: -0.2742
    Cell Significance Index: -2.6400
  • Cell Name: OFF-bipolar cell (CL0000750)
    Fold Change: -0.2849
    Cell Significance Index: -2.5100
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: -0.2909
    Cell Significance Index: -2.4500
  • Cell Name: bronchial smooth muscle cell (CL0002598)
    Fold Change: -0.3128
    Cell Significance Index: -2.0900
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: -0.3129
    Cell Significance Index: -2.4700
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.3174
    Cell Significance Index: -2.6200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** SNORA69 is a small nucleolar RNA (snoRNA) that belongs to the H/ACA box family. snoRNAs are small, non-coding RNAs that are involved in various aspects of RNA processing, including rRNA modification, splicing, and the biogenesis of small RNAs. SNORA69 is specifically characterized by its H/ACA box motif, which is a conserved sequence element that is essential for its function. The expression of SNORA69 is highly restricted, with significant expression observed in pericyte, cardiac endothelial cell, and immune cells, underscoring its potential role in cellular differentiation and function. **Pathways and Functions:** The pathways and functions of SNORA69 are multifaceted and involve various aspects of RNA processing and cellular differentiation. SNORA69 is involved in the regulation of rRNA modification, which is essential for the biogenesis of ribosomes. Additionally, SNORA69 is involved in the regulation of small RNA biogenesis, including the production of microRNAs and small interfering RNAs. SNORA69 also plays a role in the regulation of gene expression, with studies suggesting that it may act as a regulator of the cell cycle and apoptosis. Furthermore, SNORA69 has been implicated in the regulation of cellular differentiation, with studies suggesting that it may play a role in the development of pericytes and cardiac endothelial cells. **Clinical Significance:** The clinical significance of SNORA69 is an area of active research, with studies suggesting that alterations in SNORA69 expression may be involved in various diseases, including cancer and immunological disorders. For example, studies have suggested that SNORA69 may play a role in the regulation of the immune response, with alterations in SNORA69 expression observed in various immune cells, including macrophages and NK T cells. Additionally, SNORA69 has been implicated in the regulation of cellular differentiation, with studies suggesting that alterations in SNORA69 expression may be involved in the development of cardiovascular diseases. Further research is needed to fully elucidate the clinical significance of SNORA69, but the available data suggest that it may be an important regulator of cellular function and disease. In conclusion, SNORA69 is a small nucleolar RNA that plays a crucial role in RNA processing and cellular differentiation. Its expression is highly restricted, with significant expression observed in pericyte, cardiac endothelial cell, and immune cells, underscoring its potential role in cellular function and disease. Further research is needed to fully elucidate the pathways and functions of SNORA69, but the available data suggest that it may be an important regulator of cellular function and disease.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.