Details for: GRM1
Associated with
Cells (max top 100)
(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: stellate neuron (CL0000122)
Fold Change: 3.06
Marker Score: 16462.5 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 2.82
Marker Score: 8032 - Cell Name: neuronal brush cell (CL0000555)
Fold Change: 2.68
Marker Score: 8971 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 2.44
Marker Score: 48437 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 2.16
Marker Score: 4084 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 2.06
Marker Score: 15782 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.02
Marker Score: 124320 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 1.79
Marker Score: 752 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 1.7
Marker Score: 3458.5 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.66
Marker Score: 17175.5 - Cell Name: neuron (CL0000540)
Fold Change: 1.66
Marker Score: 6744 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.65
Marker Score: 15683 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 1.64
Marker Score: 2760 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.63
Marker Score: 2522 - Cell Name: mural cell (CL0008034)
Fold Change: 1.46
Marker Score: 167864 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 1.37
Marker Score: 871 - Cell Name: granule cell (CL0000120)
Fold Change: 1.37
Marker Score: 10331.5 - Cell Name: CNS interneuron (CL0000402)
Fold Change: 1.33
Marker Score: 641 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 1.3
Marker Score: 779 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 1.26
Marker Score: 48036 - Cell Name: macroglial cell (CL0000126)
Fold Change: 1.24
Marker Score: 2841 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.22
Marker Score: 4733 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.15
Marker Score: 18044.5 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 1.14
Marker Score: 311 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 1.13
Marker Score: 38298 - Cell Name: goblet cell (CL0000160)
Fold Change: 1.13
Marker Score: 7497 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 1.12
Marker Score: 328 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 1.09
Marker Score: 350 - Cell Name: glial cell (CL0000125)
Fold Change: 1.06
Marker Score: 1170 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 1.04
Marker Score: 797 - Cell Name: epithelial cell of alveolus of lung (CL0010003)
Fold Change: 1.01
Marker Score: 451 - Cell Name: brainstem motor neuron (CL2000047)
Fold Change: 1
Marker Score: 580 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71813 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1
Marker Score: 2537 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48038 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 0.99
Marker Score: 9267 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30407 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.93
Marker Score: 5331 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 0.92
Marker Score: 7866 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.92
Marker Score: 2742 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.87
Marker Score: 260 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5287 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 0.86
Marker Score: 3974 - Cell Name: interneuron (CL0000099)
Fold Change: 0.84
Marker Score: 383 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1264 - Cell Name: brush cell (CL0002204)
Fold Change: 0.78
Marker Score: 710 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.77
Marker Score: 397.5 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 0.77
Marker Score: 2187 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.7
Marker Score: 180.5 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.7
Marker Score: 269 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.68
Marker Score: 324 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.68
Marker Score: 447 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 0.67
Marker Score: 14206 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 0.65
Marker Score: 363 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.62
Marker Score: 1451 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.61
Marker Score: 489 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 0.6
Marker Score: 740 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.6
Marker Score: 187 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 0.56
Marker Score: 146 - Cell Name: astrocyte (CL0000127)
Fold Change: 0.55
Marker Score: 477 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 0.55
Marker Score: 20303 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 0.51
Marker Score: 213 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 0.5
Marker Score: 627 - Cell Name: pro-B cell (CL0000826)
Fold Change: 0.49
Marker Score: 476 - Cell Name: neuronal receptor cell (CL0000006)
Fold Change: 0.48
Marker Score: 212 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 0.46
Marker Score: 6949 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 0.45
Marker Score: 516 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 0.43
Marker Score: 876 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: 0.42
Marker Score: 1757 - Cell Name: rod bipolar cell (CL0000751)
Fold Change: 0.42
Marker Score: 219.5 - Cell Name: endothelial cell (CL0000115)
Fold Change: 0.42
Marker Score: 372 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: 0.39
Marker Score: 388 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 0.39
Marker Score: 255.5 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 0.38
Marker Score: 1560 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 0.38
Marker Score: 224 - Cell Name: microglial cell (CL0000129)
Fold Change: 0.37
Marker Score: 679 - Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: 0.36
Marker Score: 1892 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.36
Marker Score: 95 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 0.34
Marker Score: 339 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: 0.33
Marker Score: 3366 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 0.32
Marker Score: 7093 - Cell Name: B cell (CL0000236)
Fold Change: 0.32
Marker Score: 300 - Cell Name: ependymal cell (CL0000065)
Fold Change: 0.31
Marker Score: 108 - Cell Name: monocyte (CL0000576)
Fold Change: 0.3
Marker Score: 386 - Cell Name: meningeal macrophage (CL0000879)
Fold Change: 0.28
Marker Score: 79 - Cell Name: retinal bipolar neuron (CL0000748)
Fold Change: 0.26
Marker Score: 2230 - Cell Name: glycinergic amacrine cell (CL4030028)
Fold Change: 0.26
Marker Score: 246 - Cell Name: renal principal cell (CL0005009)
Fold Change: 0.25
Marker Score: 190 - Cell Name: retinal pigment epithelial cell (CL0002586)
Fold Change: 0.24
Marker Score: 72 - Cell Name: myeloid cell (CL0000763)
Fold Change: 0.24
Marker Score: 382 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.23
Marker Score: 272 - Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
Fold Change: 0.22
Marker Score: 592 - Cell Name: kidney proximal convoluted tubule epithelial cell (CL1000838)
Fold Change: 0.21
Marker Score: 427 - Cell Name: mast cell (CL0000097)
Fold Change: 0.19
Marker Score: 112 - Cell Name: ganglion interneuron (CL0000397)
Fold Change: 0.17
Marker Score: 53 - Cell Name: pericyte (CL0000669)
Fold Change: 0.17
Marker Score: 102 - Cell Name: macrophage (CL0000235)
Fold Change: 0.17
Marker Score: 194 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 0.17
Marker Score: 99.5 - Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 0.17
Marker Score: 69.5 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 0.17
Marker Score: 405
Hover over a box to see details here...
Hover over a box to see details here...
Hover over a box to see details here...
Other Information
Genular Protein ID: 865678979
Symbol: GRM1_HUMAN
Name: Metabotropic glutamate receptor 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7476890
Title: Cloning and expression of a human metabotropic glutamate receptor 1 alpha: enhanced coupling on co-transfection with a glutamate transporter.
PubMed ID: 7476890
PubMed ID: 9076744
Title: Human metabotropic glutamate receptor 1: mRNA distribution, chromosome localization and functional expression of two splice variants.
PubMed ID: 9076744
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 22901947
Title: Autosomal-recessive congenital cerebellar ataxia is caused by mutations in metabotropic glutamate receptor 1.
PubMed ID: 22901947
PubMed ID: 28886343
Title: Dominant Mutations in GRM1 Cause Spinocerebellar Ataxia Type 44.
PubMed ID: 28886343
PubMed ID: 24603153
Title: Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator.
PubMed ID: 24603153
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
PubMed ID: 26308914
Title: The role of a novel TRMT1 gene mutation and rare grm1 gene defect in intellectual disability in two azeri families.
PubMed ID: 26308914
Sequence Information:
- Length: 1194
- Mass: 132357
- Checksum: 0A633505F6D51909
- Sequence:
MVGLLLFFFP AIFLEVSLLP RSPGRKVLLA GASSQRSVAR MDGDVIIGAL FSVHHQPPAE KVPERKCGEI REQYGIQRVE AMFHTLDKIN ADPVLLPNIT LGSEIRDSCW HSSVALEQSI EFIRDSLISI RDEKDGINRC LPDGQSLPPG RTKKPIAGVI GPGSSSVAIQ VQNLLQLFDI PQIAYSATSI DLSDKTLYKY FLRVVPSDTL QARAMLDIVK RYNWTYVSAV HTEGNYGESG MDAFKELAAQ EGLCIAHSDK IYSNAGEKSF DRLLRKLRER LPKARVVVCF CEGMTVRGLL SAMRRLGVVG EFSLIGSDGW ADRDEVIEGY EVEANGGITI KLQSPEVRSF DDYFLKLRLD TNTRNPWFPE FWQHRFQCRL PGHLLENPNF KRICTGNESL EENYVQDSKM GFVINAIYAM AHGLQNMHHA LCPGHVGLCD AMKPIDGSKL LDFLIKSSFI GVSGEEVWFD EKGDAPGRYD IMNLQYTEAN RYDYVHVGTW HEGVLNIDDY KIQMNKSGVV RSVCSEPCLK GQIKVIRKGE VSCCWICTAC KENEYVQDEF TCKACDLGWW PNADLTGCEP IPVRYLEWSN IESIIAIAFS CLGILVTLFV TLIFVLYRDT PVVKSSSREL CYIILAGIFL GYVCPFTLIA KPTTTSCYLQ RLLVGLSSAM CYSALVTKTN RIARILAGSK KKICTRKPRF MSAWAQVIIA SILISVQLTL VVTLIIMEPP MPILSYPSIK EVYLICNTSN LGVVAPLGYN GLLIMSCTYY AFKTRNVPAN FNEAKYIAFT MYTTCIIWLA FVPIYFGSNY KIITTCFAVS LSVTVALGCM FTPKMYIIIA KPERNVRSAF TTSDVVRMHV GDGKLPCRSN TFLNIFRRKK AGAGNANSNG KSVSWSEPGG GQVPKGQHMW HRLSVHVKTN ETACNQTAVI KPLTKSYQGS GKSLTFSDTS TKTLYNVEEE EDAQPIRFSP PGSPSMVVHR RVPSAATTPP LPSHLTAEET PLFLAEPALP KGLPPPLQQQ QQPPPQQKSL MDQLQGVVSN FSTAIPDFHA VLAGPGGPGN GLRSLYPPPP PPQHLQMLPL QLSTFGEELV SPPADDDDDS ERFKLLQEYV YEHEREGNTE EDELEEEEED LQAASKLTPD DSPALTPPSP FRDSVASGSS VPSSPVSESV LCTPPNVSYA SVILRDYKQS SSTL
Genular Protein ID: 2676243081
Symbol: Q59HC2_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 901
- Mass: 100881
- Checksum: 511EC22B381DE455
- Sequence:
LFFFPAIFLE VSLLPRSPGR KVLLAGASSQ RSVARMDGDV IIGALFSVHH QPPAEKVPER KCGEIREQYG IQRVEAMFHT LDKINADPVL LPNITLGSEI RDSCWHSSVA LEQSIEFIRD SLISIRDEKD GINRCLPDGQ SLPPGRTKKP IAGVIGPGSS SVAIQVQNLL QLFDIPQIAY SATSIDLSDK TLYKYFLRVV PSDTLQARAM LDIVKRYNWT YVSAVHTEGN YGESGMDAFK ELAAQEGLCI AHSDKIYSNA GEKSFDRLLR KLRERLPKAR VVVCFCEGMT VRGLLSAMRR LGVVGEFSLI GSDGWADRDE VIEGYEVEAN GGITIKLQSP EVRSFDDYFL KLRLDTNTRN PWFPEFWQHR FQCRLPGHLL ENPNFKRICT GNESLEENYV QDSKMGFVIN AIYAMAHGLQ NMHHALCPGH VGLCDAMKPI DGSKLLDFLI KSSFIGVSGE EVWFDEKGDA PGRYDIMNLQ YTEANRYDYV HVGTWHEGVL NIDDYKIQMN KSGVVRSVCS EPCLKGQIKV IRKGEVSCCW ICTACKENEY VQDEFTCKAC DLGWWPNADL TGCEPIPVRY LEWSNIESII AIAFSCLGIL VTLFVTLIFV LYRDTPVVKS SSRELCYIIL AGIFLGYVCP FTLIAKPTTT SCYLQRLLVG LSSAMCYSAL VTKTNRIARI LAGSKKKICT RKPRFMSAWA QVIIASILIS VQLTLVVTLI IMEPPMPILS YPSIKEVYLI CNTSNLGVVA PLGYNGLLIM SCTYYAFKTR NVPANFNEAK YIAFTMYTTC IIWLAFVPIY FGSNYKIITT CFAVSLSVTV ALGCMFTPKM YIIIAKPERN VRSAFTTSDV VRMHVGDGKL PCRSNTFLNI FRRKKAGAEN AKKRQPEFSP TSQCPSAHVQ L
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.