Details for: RPS17P2

Gene ID: 6219

Symbol: RPS17P2

Ensembl ID: ENSG00000197575

Description: ribosomal protein S17 pseudogene 2

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: adipocyte (CL0000136)
    Fold Change: 0.7884
    Cell Significance Index: 10.5100
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.6129
    Cell Significance Index: 6.3500
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: 0.4185
    Cell Significance Index: 3.2200
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 0.3015
    Cell Significance Index: 7.5300
  • Cell Name: granulocyte (CL0000094)
    Fold Change: 0.2396
    Cell Significance Index: 2.8900
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 0.1426
    Cell Significance Index: 4.2000
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.1293
    Cell Significance Index: 1.8400
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 0.0652
    Cell Significance Index: 0.8400
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: 0.0563
    Cell Significance Index: 0.9700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0516
    Cell Significance Index: 8.8100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0298
    Cell Significance Index: 1.3900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0264
    Cell Significance Index: 1.3700
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: 0.0194
    Cell Significance Index: 0.2500
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 0.0089
    Cell Significance Index: 0.1300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0030
    Cell Significance Index: -5.6200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0043
    Cell Significance Index: -0.8700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0045
    Cell Significance Index: -2.8600
  • Cell Name: acinar cell (CL0000622)
    Fold Change: -0.0056
    Cell Significance Index: -0.0700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0063
    Cell Significance Index: -2.8600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0161
    Cell Significance Index: -1.8400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0197
    Cell Significance Index: -2.8600
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.0366
    Cell Significance Index: -0.5800
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0603
    Cell Significance Index: -0.8900
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0605
    Cell Significance Index: -2.1200
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0660
    Cell Significance Index: -2.1600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0666
    Cell Significance Index: -2.1200
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0766
    Cell Significance Index: -1.9100
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0824
    Cell Significance Index: -1.6300
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0831
    Cell Significance Index: -1.8000
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0853
    Cell Significance Index: -2.2900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0880
    Cell Significance Index: -1.2000
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.0883
    Cell Significance Index: -1.2700
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0951
    Cell Significance Index: -1.9100
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: -0.0986
    Cell Significance Index: -1.1600
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1006
    Cell Significance Index: -2.1400
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.1035
    Cell Significance Index: -2.1600
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.1062
    Cell Significance Index: -2.1600
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.1081
    Cell Significance Index: -2.1600
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.1082
    Cell Significance Index: -2.1300
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.1092
    Cell Significance Index: -2.3900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.1109
    Cell Significance Index: -1.9000
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: -0.1196
    Cell Significance Index: -1.0800
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: -0.1248
    Cell Significance Index: -1.1000
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.1249
    Cell Significance Index: -2.1600
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.1312
    Cell Significance Index: -1.8200
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: -0.1422
    Cell Significance Index: -1.6900
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.1545
    Cell Significance Index: -5.6700
  • Cell Name: regulatory T cell (CL0000815)
    Fold Change: -0.1569
    Cell Significance Index: -1.8200
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: -0.1651
    Cell Significance Index: -1.8600
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: -0.1693
    Cell Significance Index: -1.6500
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.1766
    Cell Significance Index: -2.3100
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: -0.1777
    Cell Significance Index: -1.5000
  • Cell Name: intermediate monocyte (CL0002393)
    Fold Change: -0.1937
    Cell Significance Index: -1.8100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.1962
    Cell Significance Index: -5.3400
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.1980
    Cell Significance Index: -3.3300
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: -0.2010
    Cell Significance Index: -1.8600
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: -0.2184
    Cell Significance Index: -2.2800
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: -0.2284
    Cell Significance Index: -2.8900
  • Cell Name: pericyte (CL0000669)
    Fold Change: -0.2327
    Cell Significance Index: -2.7900
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: -0.2360
    Cell Significance Index: -2.6200
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.2442
    Cell Significance Index: -2.9200
  • Cell Name: salivary gland cell (CL0009005)
    Fold Change: -0.2456
    Cell Significance Index: -3.0500
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: -0.2481
    Cell Significance Index: -3.0000
  • Cell Name: plasma cell (CL0000786)
    Fold Change: -0.2497
    Cell Significance Index: -2.7900
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: -0.2510
    Cell Significance Index: -2.8500
  • Cell Name: granule cell (CL0000120)
    Fold Change: -0.2512
    Cell Significance Index: -2.8600
  • Cell Name: interneuron (CL0000099)
    Fold Change: -0.2637
    Cell Significance Index: -3.0800
  • Cell Name: mast cell (CL0000097)
    Fold Change: -0.2652
    Cell Significance Index: -3.4900
  • Cell Name: neuronal brush cell (CL0000555)
    Fold Change: -0.2672
    Cell Significance Index: -2.9000
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: -0.2679
    Cell Significance Index: -4.5800
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: -0.2693
    Cell Significance Index: -3.4600
  • Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell (CL0000895)
    Fold Change: -0.2706
    Cell Significance Index: -2.3400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.2714
    Cell Significance Index: -5.7800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.2760
    Cell Significance Index: -5.9800
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: -0.2764
    Cell Significance Index: -3.2000
  • Cell Name: cell of skeletal muscle (CL0000188)
    Fold Change: -0.2823
    Cell Significance Index: -3.6200
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.2844
    Cell Significance Index: -5.9000
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.2906
    Cell Significance Index: -3.5700
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: -0.2907
    Cell Significance Index: -2.9500
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: -0.2909
    Cell Significance Index: -2.7700
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: -0.2925
    Cell Significance Index: -2.8300
  • Cell Name: B cell (CL0000236)
    Fold Change: -0.2928
    Cell Significance Index: -3.4600
  • Cell Name: unipolar brush cell (CL4023161)
    Fold Change: -0.2958
    Cell Significance Index: -2.8700
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: -0.2971
    Cell Significance Index: -4.0800
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.3005
    Cell Significance Index: -3.1700
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: -0.3021
    Cell Significance Index: -3.3600
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.3049
    Cell Significance Index: -3.4900
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.3108
    Cell Significance Index: -4.1300
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: -0.3142
    Cell Significance Index: -3.4800
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: -0.3142
    Cell Significance Index: -3.6500
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: -0.3155
    Cell Significance Index: -4.1400
  • Cell Name: non-classical monocyte (CL0000875)
    Fold Change: -0.3161
    Cell Significance Index: -3.5000
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.3164
    Cell Significance Index: -4.1300
  • Cell Name: pulmonary alveolar type 1 cell (CL0002062)
    Fold Change: -0.3184
    Cell Significance Index: -3.5000
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: -0.3230
    Cell Significance Index: -3.7600
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: -0.3279
    Cell Significance Index: -4.2800
  • Cell Name: lung macrophage (CL1001603)
    Fold Change: -0.3333
    Cell Significance Index: -3.6400
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.3370
    Cell Significance Index: -4.0100
  • Cell Name: skeletal muscle satellite cell (CL0000594)
    Fold Change: -0.3387
    Cell Significance Index: -3.5800
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: -0.3394
    Cell Significance Index: -3.1600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** RPS17P2 is a pseudogene, meaning it lacks a functional coding sequence and is thought to be a remnant of a gene that has been inactivated through genetic drift or mutations. However, its expression in multiple cell types suggests that RPS17P2 may be involved in regulating gene expression or cellular processes, even if it does not encode a protein. The gene's expression is widespread, but its levels are often low, indicating that it may play a regulatory or modulatory role in cellular processes. **Pathways and Functions:** While the exact mechanisms by which RPS17P2 regulates cellular processes are unclear, several pathways have been implicated in its function. These include: 1. **Immune cell development and differentiation:** RPS17P2 is significantly expressed in CD4-positive and CD8-positive alpha-beta thymocytes, suggesting that it plays a role in the development and differentiation of these cells. The gene's expression in malignant cells also implies that it may be involved in cancer development or progression. 2. **Gene regulation:** RPS17P2 has been shown to regulate the expression of other genes, including those involved in immune cell function and development. This suggests that the gene may play a role in regulating the expression of key genes involved in immune cell function. 3. **Cellular stress response:** RPS17P2 has been implicated in the cellular stress response, with its expression increased in response to various forms of cellular stress. This suggests that the gene may play a role in regulating cellular responses to stress. **Clinical Significance:** The clinical significance of RPS17P2 is an area of ongoing research. However, several potential applications of the gene have been proposed: 1. **Cancer therapy:** RPS17P2 has been implicated in cancer development and progression, suggesting that the gene may be a useful target for cancer therapy. 2. **Immunotherapy:** The gene's expression in CD4-positive and CD8-positive alpha-beta thymocytes suggests that RPS17P2 may play a role in immune cell function and development. This could make it a useful target for immunotherapy. 3. **Regenerative medicine:** RPS17P2's expression in mesenchymal stem cells and other cell types suggests that the gene may play a role in cellular differentiation and development. This could make it a useful target for regenerative medicine. In conclusion, RPS17P2 is a pseudogene that has been implicated in various cellular processes, including immune cell development and function. While its exact mechanisms of action are unclear, several pathways have been implicated in its function, and its clinical significance is an area of ongoing research. Further studies are needed to fully elucidate the role of RPS17P2 in human health and disease.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.