Details for: MTA1

Gene ID: 9112

Symbol: MTA1

Ensembl ID: ENSG00000182979

Description: metastasis associated 1

Associated with

Other Information

Genular Protein ID: 2839155052

Symbol: MTA1_HUMAN

Name: Metastasis-associated protein MTA1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8083195

Title: A novel candidate metastasis-associated gene, mta1, differentially expressed in highly metastatic mammary adenocarcinoma cell lines. cDNA cloning, expression, and protein analyses.

PubMed ID: 8083195

DOI: 10.1016/s0021-9258(17)31603-4

PubMed ID: 7607577

Title: Analysis of the complete sequence of the novel metastasis-associated candidate gene, mta1, differentially expressed in mammary adenocarcinoma and breast cancer cell lines.

PubMed ID: 7607577

DOI: 10.1016/0378-1119(94)00410-t

PubMed ID: 12167865

Title: A naturally occurring MTA1 variant sequesters oestrogen receptor-alpha in the cytoplasm.

PubMed ID: 12167865

DOI: 10.1038/nature00889

PubMed ID: 12508121

Title: The DNA sequence and analysis of human chromosome 14.

PubMed ID: 12508121

DOI: 10.1038/nature01348

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9885572

Title: NURD, a novel complex with both ATP-dependent chromatin-remodeling and histone deacetylase activities.

PubMed ID: 9885572

DOI: 10.1016/s1097-2765(00)80299-3

PubMed ID: 15254226

Title: Metastasis-associated protein 1 interacts with NRIF3, an estrogen-inducible nuclear receptor coregulator.

PubMed ID: 15254226

DOI: 10.1128/mcb.24.15.6581-6591.2004

PubMed ID: 15077195

Title: Metastatic tumor antigen 1 short form (MTA1s) associates with casein kinase I-gamma2, an estrogen-responsive kinase.

PubMed ID: 15077195

DOI: 10.1038/sj.onc.1207569

PubMed ID: 15701600

Title: MBD3L2 interacts with MBD3 and components of the NuRD complex and can oppose MBD2-MeCP1-mediated methylation silencing.

PubMed ID: 15701600

DOI: 10.1074/jbc.m413492200

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 16617102

Title: MTA1, a transcriptional activator of breast cancer amplified sequence 3.

PubMed ID: 16617102

DOI: 10.1073/pnas.0601989103

PubMed ID: 16428440

Title: MBD2/NuRD and MBD3/NuRD, two distinct complexes with different biochemical and functional properties.

PubMed ID: 16428440

DOI: 10.1128/mcb.26.3.843-851.2006

PubMed ID: 17671180

Title: Identification of Pax5 as a target of MTA1 in B-cell lymphomas.

PubMed ID: 17671180

DOI: 10.1158/0008-5472.can-07-0750

PubMed ID: 25948590

Title:

PubMed ID: 25948590

DOI: 10.1158/0008-5472.can-15-1095

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 17922032

Title: MTA1-mediated transcriptional repression of BRCA1 tumor suppressor gene.

PubMed ID: 17922032

DOI: 10.1038/sj.onc.1210839

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19837670

Title: MTA1 coregulator regulates p53 stability and function.

PubMed ID: 19837670

DOI: 10.1074/jbc.m109.056499

PubMed ID: 19805145

Title: E3 ubiquitin ligase COP1 regulates the stability and functions of MTA1.

PubMed ID: 19805145

DOI: 10.1073/pnas.0908027106

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20682799

Title: Metastasis-associated protein 1 and its short form variant stimulates Wnt1 transcription through promoting its derepression from Six3 corepressor.

PubMed ID: 20682799

DOI: 10.1158/0008-5472.can-10-0909

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21965678

Title: SUMOylation and SUMO-interacting motif (SIM) of metastasis tumor antigen 1 (MTA1) synergistically regulate its transcriptional repressor function.

PubMed ID: 21965678

DOI: 10.1074/jbc.m111.267237

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22253283

Title: Metastasis-associated protein 1/nucleosome remodeling and histone deacetylase complex in cancer.

PubMed ID: 22253283

DOI: 10.1158/0008-5472.can-11-2345

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 22926524

Title: RBB, a novel transcription repressor, represses the transcription of HDM2 oncogene.

PubMed ID: 22926524

DOI: 10.1038/onc.2012.386

PubMed ID: 24413532

Title: Differential regulation of estrogen receptor alpha expression in breast cancer cells by metastasis-associated protein 1.

PubMed ID: 24413532

DOI: 10.1158/0008-5472.can-13-2020

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24970816

Title: The subcellular distribution and function of MTA1 in cancer differentiation.

PubMed ID: 24970816

DOI: 10.18632/oncotarget.2095

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 28977666

Title: CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

PubMed ID: 28977666

DOI: 10.1093/nar/gkx711

PubMed ID: 30327463

Title: PWWP2A binds distinct chromatin moieties and interacts with an MTA1-specific core NuRD complex.

PubMed ID: 30327463

DOI: 10.1038/s41467-018-06665-5

PubMed ID: 33283408

Title: Cross-linking mass spectrometry reveals the structural topology of peripheral NuRD subunits relative to the core complex.

PubMed ID: 33283408

DOI: 10.1111/febs.15650

PubMed ID: 24920672

Title: Insight into the architecture of the NuRD complex: structure of the RbAp48-MTA1 subcomplex.

PubMed ID: 24920672

DOI: 10.1074/jbc.m114.558940

Sequence Information:

  • Length: 715
  • Mass: 80786
  • Checksum: 2D5330F0489AE62E
  • Sequence:
  • MAANMYRVGD YVYFENSSSN PYLIRRIEEL NKTANGNVEA KVVCFYRRRD ISSTLIALAD 
    KHATLSVCYK AGPGADNGEE GEIEEEMENP EMVDLPEKLK HQLRHRELFL SRQLESLPAT 
    HIRGKCSVTL LNETESLKSY LEREDFFFYS LVYDPQQKTL LADKGEIRVG NRYQADITDL 
    LKEGEEDGRD QSRLETQVWE AHNPLTDKQI DQFLVVARSV GTFARALDCS SSVRQPSLHM 
    SAAAASRDIT LFHAMDTLHK NIYDISKAIS ALVPQGGPVL CRDEMEEWSA SEANLFEEAL 
    EKYGKDFTDI QQDFLPWKSL TSIIEYYYMW KTTDRYVQQK RLKAAEAESK LKQVYIPNYN 
    KPNPNQISVN NVKAGVVNGT GAPGQSPGAG RACESCYTTQ SYQWYSWGPP NMQCRLCASC 
    WTYWKKYGGL KMPTRLDGER PGPNRSNMSP HGLPARSSGS PKFAMKTRQA FYLHTTKLTR 
    IARRLCREIL RPWHAARHPY LPINSAAIKA ECTARLPEAS QSPLVLKQAV RKPLEAVLRY 
    LETHPRPPKP DPVKSVSSVL SSLTPAKVAP VINNGSPTIL GKRSYEQHNG VDGNMKKRLL 
    MPSRGLANHG QARHMGPSRN LLLNGKSYPT KVRLIRGGSL PPVKRRRMNW IDAPDDVFYM 
    ATEETRKIRK LLSSSETKRA ARRPYKPIAL RQSQALPPRP PPPAPVNDEP IVIED

Genular Protein ID: 547721089

Symbol: Q9BRL8_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 255
  • Mass: 28706
  • Checksum: 9E640D1DA92429A9
  • Sequence:
  • MKTRQAFYLH TTKLTRIARR LCREILRPWH AARHPYLPIN SAAIKAECTA RLPEASQSPL 
    VLKQAVRKPL EAVLRYLETH PRPPKPDPVK SVSSVLSSLT PAKVAPVINN GSPTILGKRS 
    YEQHNGVDGN MKKRLLMPSR GTYLGLANHG QTRHMGPSRN LLLNGKSYPT KVRLIRGGSL 
    PPVKRRRMNW IDAPDDVFYM ATEETRKIRK LLSSSETKRA ARRPYKPIAL RQSQALPPRP 
    PPPAPVNDEP IVIED

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.