ZFPM2 | ENSG00000169946 | NCBI 23414

Details for: ZFPM2

Gene ID: 23414

Symbol: ZFPM2

Ensembl ID: ENSG00000169946

Description: zinc finger protein, FOG family member 2

Associated with

Developmental biology
(R-HSA-1266738)
Factors involved in megakaryocyte development and platelet production
(R-HSA-983231)
Hemostasis
(R-HSA-109582)
Transcriptional regulation of testis differentiation
(R-HSA-9690406)
Cell differentiation
(GO:0030154)
Chromatin
(GO:0000785)
Cytoplasm
(GO:0005737)
Dna binding
(GO:0003677)
Embryonic organ development
(GO:0048568)
Fat cell differentiation
(GO:0045444)
Gonadal mesoderm development
(GO:0007506)
Heart development
(GO:0007507)
In utero embryonic development
(GO:0001701)
Lung development
(GO:0030324)
Male germ cell nucleus
(GO:0001673)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of fat cell differentiation
(GO:0045599)
Negative regulation of female gonad development
(GO:2000195)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Outflow tract septum morphogenesis
(GO:0003148)
Positive regulation of cardiac muscle cell proliferation
(GO:0060045)
Positive regulation of male gonad development
(GO:2000020)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein binding
(GO:0005515)
Right ventricular cardiac muscle tissue morphogenesis
(GO:0003221)
Rna polymerase ii-specific dna-binding transcription factor binding
(GO:0061629)
Transcription coactivator activity
(GO:0003713)
Transcription corepressor activity
(GO:0003714)
Vasculogenesis
(GO:0001570)
Ventricular septum morphogenesis
(GO:0060412)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Zinc finger protein ZFPM2
Q9NPQ0_HUMAN

Genular Protein ID: 997652480

Symbol: FOG2_HUMAN

Name: Zinc finger protein ZFPM2

UniProtKB Accession Codes:

Q8WW38 Q32MA6 Q9NPL7 Q9NPS4 Q9UNI5

Database IDs:

Citations:

PubMed ID: 10438528

Title: hFOG-2, a novel zinc finger protein, binds the co-repressor mCtBP2 and modulates GATA-mediated activation.

PubMed ID: 10438528

DOI: 10.1074/jbc.274.33.23491

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 23226341

Title: SUMOylation regulates the transcriptional repression activity of FOG-2 and its association with GATA-4.

PubMed ID: 23226341

DOI: 10.1371/journal.pone.0050637

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24549039

Title: Mutations in the FOG2/ZFPM2 gene are associated with anomalies of human testis determination.

PubMed ID: 24549039

DOI: 10.1093/hmg/ddu074

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 14517948

Title: Mutations of ZFPM2/FOG2 gene in sporadic cases of tetralogy of Fallot.

PubMed ID: 14517948

DOI: 10.1002/humu.10261

PubMed ID: 16103912

Title: Fog2 is required for normal diaphragm and lung development in mice and humans.

PubMed ID: 16103912

DOI: 10.1371/journal.pgen.0010010

PubMed ID: 20807224

Title: New mutations in ZFPM2/FOG2 gene in tetralogy of Fallot and double outlet right ventricle.

PubMed ID: 20807224

DOI: 10.1111/j.1399-0004.2010.01523.x

Sequence Information:

Length: 1151
Mass: 128159
Checksum: 680E31BA1D044C35
Sequence:

MSRRKQSKPR QIKRPLEDAI EDEEEECPSE ETDIISKGDF PLEESFSTEF GPENLSCEEV 
EYFCNKGDDE GIQETAESDG DTQSEKPGQP GVETDDWDGP GELEVFQKDG ERKIQSRQQL 
PVGTTWGPFP GKMDLNNNSL KTKAQVPMVL TAGPKWLLDV TWQGVEDNKN NCIVYSKGGQ 
LWCTTTKAIS EGEELIAFVV DFDSRLQAAS QMTLTEGMYP ARLLDSIQLL PQQAAMASIL 
PTAIVNKDIF PCKSCGIWYR SERNLQAHLM YYCSGRQREA APVSEENEDS AHQISSLCPF 
PQCTKSFSNA RALEMHLNSH SGVKMEEFLP PGASLKCTVC SYTADSVINF HQHLFSHLTQ 
AAFRCNHCHF GFQTQRELLQ HQELHVPSGK LPRESDMEHS PSATEDSLQP ATDLLTRSEL 
PQSQKAMQTK DASSDTELDK CEKKTQLFLT NQRPEIQPTT NKQSFSYTKI KSEPSSPRLA 
SSPVQPNIGP SFPVGPFLSQ FSFPQDITMV PQASEILAKM SELVHRRLRH GSSSYPPVIY 
SPLMPKGATC FECNITFNNL DNYLVHKKHY CSSRWQQMAK SPEFPSVSEK MPEALSPNTG 
QTSINLLNPA AHSADPENPL LQTSCINSST VLDLIGPNGK GHDKDFSTQT KKLSTSSNND 
DKINGKPVDV KNPSVPLVDG ESDPNKTTCE ACNITFSRHE TYMVHKQYYC ATRHDPPLKR 
SASNKVPAMQ RTMRTRKRRK MYEMCLPEQE QRPPLVQQRF LDVANLNNPC TSTQEPTEGL 
GECYHPRCDI FPGIVSKHLE TSLTINKCVP VSKCDTTHSS VSCLEMDVPI DLSKKCLSQS 
ERTTTSPKRL LDYHECTVCK ISFNKVENYL AHKQNFCPVT AHQRNDLGQL DGKVFPNPES 
ERNSPDVSYE RSIIKCEKNG NLKQPSPNGN LFSSHLATLQ GLKVFSEAAQ LIATKEENRH 
LFLPQCLYPG AIKKAKGADQ LSPYYGIKPS DYISGSLVIH NTDIEQSRNA ENESPKGQAS 
SNGCAALKKD SLPLLPKNRG MVIVNGGLKQ DERPAANPQQ ENISQNPQHE DDHKSPSWIS 
ENPLAANENV SPGIPSAEEQ LSSIAKGVNG SSQAPTSGKY CRLCDIQFNN LSNFITHKKF 
YCSSHAAEHV K

Genular Protein ID: 979364591

Symbol: Q9NPQ0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q9NPQ0

Database IDs:

Sequence Information:

Length: 79
Mass: 8561
Checksum: 6E8CDD7A7D4DB23A
Sequence:

HKSPSWISEN PLAANENVSP GIPSAEEQLS SIAKGVNGSS QAPTSGKYCR LCDIQFNNLS 
NFITHKKFYC SSHAAEHVK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: ZFPM2

Associated with

Other Information

hFOG-2, a novel zinc finger protein, binds the co-repressor mCtBP2 and modulates GATA-mediated activation. PubMed ID: 10438528

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

SUMOylation regulates the transcriptional repression activity of FOG-2 and its association with GATA-4. PubMed ID: 23226341

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

Mutations in the FOG2/ZFPM2 gene are associated with anomalies of human testis determination. PubMed ID: 24549039

Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. PubMed ID: 28112733

Mutations of ZFPM2/FOG2 gene in sporadic cases of tetralogy of Fallot. PubMed ID: 14517948

Fog2 is required for normal diaphragm and lung development in mice and humans. PubMed ID: 16103912

New mutations in ZFPM2/FOG2 gene in tetralogy of Fallot and double outlet right ventricle. PubMed ID: 20807224