Details for: ZFPM2
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
-
CSI 46.03rCSI 67.66%PRS 90.12
-
CSI 43.15rCSI 61.92%PRS 87.41
-
CSI 36.19rCSI 45.02%PRS 82.38
-
CSI 30.43rCSI 55.29%PRS 89.12
-
CSI 30.43rCSI 39.07%PRS 87.3
-
CSI 27.74rCSI 55.69%PRS 89.54
-
CSI 27.06rCSI 56.14%PRS 92.57
-
CSI 26.31rCSI 42.31%PRS 85.45
-
CSI 26.06rCSI 31.13%PRS 84.48
-
CSI 26.05rCSI 57.33%PRS 78.99
-
CSI 23.96rCSI 51.99%PRS 84.7
-
CSI 23rCSI 55.89%PRS 82.43
-
CSI 21.54rCSI 29.47%PRS 88.11
-
CSI 21.29rCSI 29.57%PRS 92.5
-
CSI 20.22rCSI 52.67%PRS 88.95
-
CSI 19.7rCSI 34.07%PRS 90.18
-
CSI 19.59rCSI 61.23%PRS 85.48
-
CSI 19.12rCSI 51.09%PRS 90.25
-
CSI 18.38rCSI 29.32%PRS 87.88
-
CSI 17.95rCSI 47.81%PRS 83.78
-
CSI 16.7rCSI 33.89%PRS 79.42
-
CSI 16.31rCSI 47.26%PRS 87.45
-
CSI 15.65rCSI 56.31%PRS 82.72
-
CSI 15.44rCSI 52.89%PRS 83.67
-
CSI 14.99rCSI 35.85%PRS 85.88
-
CSI 14.31rCSI 46.06%PRS 90.76
-
CSI 14.02rCSI 57.15%PRS 88.06
-
CSI 13.68rCSI 44.96%PRS 84.7
-
CSI 12.67rCSI 47.82%PRS 82.25
-
CSI 12.59rCSI 47.15%PRS 91.06
-
CSI 12.48rCSI 21.88%PRS 91.69
-
CSI 12.35rCSI 24.48%PRS 94.23
-
CSI 12.31rCSI 21.7%PRS 95.75
-
CSI 11.65rCSI 13.46%PRS 87.66
-
CSI 11.57rCSI 59.27%PRS 95.01
-
CSI 11.48rCSI 55%PRS 94.64
-
CSI 11.15rCSI 59.26%PRS 88.51
-
CSI 11.07rCSI 20.74%PRS 87.64
-
CSI 10.34rCSI 29.4%PRS 90.99
-
CSI 10.16rCSI 27.06%PRS 73.28
-
CSI 9.93rCSI 58.46%PRS 84.83
-
CSI 9.92rCSI 7.84%PRS 88.94
-
CSI 9.8rCSI 22.63%PRS 87.09
-
CSI 9.62rCSI 30.77%PRS 92.97
-
CSI 9.57rCSI 32.42%PRS 90.5
-
CSI 9.48rCSI 30.84%PRS 91.63
-
CSI 9.39rCSI 14.99%PRS 95.52
-
CSI 9.36rCSI 12.01%PRS 90.78
-
CSI 8.97rCSI 13.68%PRS 91.42
-
CSI 8.67rCSI 11.18%PRS 85.43
-
CSI 8.44rCSI 24.27%PRS 84.96
-
CSI 8.24rCSI 18.48%PRS 84.7
-
CSI 7.94rCSI 8.7%PRS 95.14
-
CSI 7.79rCSI 9.69%PRS 93.28
-
CSI 7.55rCSI 18.03%PRS 95.61
-
CSI 7.3rCSI 20.13%PRS 92.39
-
CSI 7.26rCSI 18.37%PRS 95.33
-
CSI 7.25rCSI 28.36%PRS 81.39
-
CSI 7.11rCSI 18.28%PRS 90.65
-
CSI 7.09rCSI 30.15%PRS 88.66
-
CSI 7rCSI 20.66%PRS 93.62
-
CSI 6.96rCSI 16.6%PRS 88.99
-
CSI 6.84rCSI 9.7%PRS 92.54
-
CSI 6.83rCSI 30.05%PRS 84.84
-
CSI 6.66rCSI 41.61%PRS 88.8
-
CSI 6.65rCSI 6.19%PRS 95.03
-
CSI 6.63rCSI 26.77%PRS 94.44
-
CSI 6.59rCSI 10.07%PRS 92.99
-
CSI 6.26rCSI 12.86%PRS 84.35
-
CSI 6.21rCSI 9.88%PRS 90.53
-
CSI 5.78rCSI 13.9%PRS 94.31
-
CSI 5.35rCSI 36.41%PRS 86.92
-
CSI 5.31rCSI 12.11%PRS 88.84
-
CSI 5.11rCSI 27.96%PRS 90.5
-
CSI 5.04rCSI 19.69%PRS 87.71
-
CSI 5.04rCSI 13.3%PRS 96.56
-
CSI 4.93rCSI 21.93%PRS 93.99
-
CSI 4.85rCSI 6.72%PRS 91.4
-
CSI 4.76rCSI 26.9%PRS 85.52
-
CSI 4.58rCSI 12.87%PRS 90.86
-
CSI 4.47rCSI 7.06%PRS 94.72
-
CSI 4.39rCSI 16.7%PRS 88.58
-
CSI 4.38rCSI 3.56%PRS 93.49
-
CSI 4.29rCSI 44.43%PRS 88.58
-
CSI 4.16rCSI 26.08%PRS 77.28
-
CSI 4.06rCSI 13.62%PRS 83.15
-
CSI 3.99rCSI 17.8%PRS 97.31
-
CSI 3.89rCSI 18.6%PRS 91.14
-
CSI 3.68rCSI 32.35%PRS 83.92
-
CSI 3.65rCSI 26.8%PRS 88.05
-
CSI 3.6rCSI 5.9%PRS 88.71
-
CSI 3.41rCSI 15.25%PRS 81.78
-
CSI 3.08rCSI 7.8%PRS 89.98
-
CSI 3.05rCSI 9.55%PRS 87.17
-
CSI 2.86rCSI 6.82%PRS 94.38
-
CSI 2.72rCSI 19.27%PRS 89.09
-
CSI 2.56rCSI 27.14%PRS 90.84
-
CSI 2.45rCSI 3.94%PRS 87.58
-
CSI 2.42rCSI 13.49%PRS 94.73
-
CSI 2.39rCSI 9.48%PRS 88.91
-
CSI 0.4rCSI 3.6%PRS 87.8%
-
CSI 0.9rCSI 5.5%PRS 88.3%
-
CSI 1.3rCSI 3.5%PRS 95.8%
-
CSI 1.5rCSI 3.7%PRS 90.3%
-
CSI 1.5rCSI 5.6%PRS 84.7%
-
CSI 1.8rCSI 3.1%PRS 83.9%
-
CSI 1.8rCSI 7.3%PRS 96.9%
-
CSI 1.8rCSI 14.7%PRS 92.6%
-
CSI 1.8rCSI 3.1%PRS 84.5%
-
CSI 1.9rCSI 29.3%PRS 94.2%
-
CSI 1.9rCSI 10.2%PRS 93.8%
-
CSI 2.0rCSI 9.7%PRS 95.9%
-
CSI 2.3rCSI 55.8%PRS 82.2%
-
CSI 2.3rCSI 55.5%PRS 82.3%
-
CSI 2.4rCSI 9.5%PRS 88.9%
-
CSI 2.4rCSI 13.5%PRS 94.7%
-
CSI 2.5rCSI 3.9%PRS 87.6%
-
CSI 2.6rCSI 27.1%PRS 90.8%
-
CSI 2.7rCSI 19.3%PRS 89.1%
-
CSI 2.9rCSI 6.8%PRS 94.4%
-
CSI 3.1rCSI 9.6%PRS 87.2%
-
CSI 3.1rCSI 7.8%PRS 90.0%
-
CSI 3.4rCSI 15.3%PRS 81.8%
-
CSI 3.6rCSI 5.9%PRS 88.7%
-
CSI 3.7rCSI 26.8%PRS 88.1%
-
CSI 3.7rCSI 32.4%PRS 83.9%
-
CSI 3.9rCSI 18.6%PRS 91.1%
-
CSI 4.0rCSI 17.8%PRS 97.3%
-
CSI 4.1rCSI 13.6%PRS 83.2%
-
CSI 4.2rCSI 26.1%PRS 77.3%
-
CSI 4.3rCSI 44.4%PRS 88.6%
-
CSI 4.4rCSI 3.6%PRS 93.5%
-
CSI 4.4rCSI 16.7%PRS 88.6%
-
CSI 4.5rCSI 7.1%PRS 94.7%
-
CSI 4.6rCSI 12.9%PRS 90.9%
-
CSI 4.8rCSI 26.9%PRS 85.5%
-
CSI 4.9rCSI 6.7%PRS 91.4%
-
CSI 4.9rCSI 21.9%PRS 94.0%
-
CSI 5.0rCSI 13.3%PRS 96.6%
-
CSI 5.0rCSI 19.7%PRS 87.7%
-
CSI 5.1rCSI 28.0%PRS 90.5%
-
CSI 5.3rCSI 12.1%PRS 88.8%
-
CSI 5.4rCSI 36.4%PRS 86.9%
-
CSI 5.8rCSI 13.9%PRS 94.3%
-
CSI 6.2rCSI 9.9%PRS 90.5%
-
CSI 6.3rCSI 12.9%PRS 84.4%
-
CSI 6.6rCSI 10.1%PRS 93.0%
-
CSI 6.6rCSI 26.8%PRS 94.4%
-
CSI 6.7rCSI 6.2%PRS 95.0%
-
CSI 6.7rCSI 41.6%PRS 88.8%
-
CSI 6.8rCSI 30.1%PRS 84.8%
-
CSI 6.8rCSI 9.7%PRS 92.5%
-
CSI 7.0rCSI 16.6%PRS 89.0%
-
CSI 7.0rCSI 20.7%PRS 93.6%
-
CSI 7.1rCSI 30.2%PRS 88.7%
-
CSI 7.1rCSI 18.3%PRS 90.7%
-
CSI 7.3rCSI 28.4%PRS 81.4%
-
CSI 7.3rCSI 18.4%PRS 95.3%
-
CSI 7.3rCSI 20.1%PRS 92.4%
-
CSI 7.6rCSI 18.0%PRS 95.6%
-
CSI 7.8rCSI 9.7%PRS 93.3%
-
CSI 7.9rCSI 8.7%PRS 95.1%
-
CSI 8.2rCSI 18.5%PRS 84.7%
-
CSI 8.4rCSI 24.3%PRS 85.0%
-
CSI 8.7rCSI 11.2%PRS 85.4%
-
CSI 9.0rCSI 13.7%PRS 91.4%
-
CSI 9.4rCSI 12.0%PRS 90.8%
-
CSI 9.4rCSI 15.0%PRS 95.5%
-
CSI 9.5rCSI 30.8%PRS 91.6%
-
CSI 9.6rCSI 32.4%PRS 90.5%
-
CSI 9.6rCSI 30.8%PRS 93.0%
-
CSI 9.8rCSI 22.6%PRS 87.1%
-
CSI 9.9rCSI 7.8%PRS 88.9%
-
CSI 9.9rCSI 58.5%PRS 84.8%
-
CSI 10.2rCSI 27.1%PRS 73.3%
-
CSI 10.3rCSI 29.4%PRS 91.0%
-
CSI 11.1rCSI 20.7%PRS 87.6%
-
CSI 11.2rCSI 59.3%PRS 88.5%
-
CSI 11.5rCSI 55.0%PRS 94.6%
-
CSI 11.6rCSI 59.3%PRS 95.0%
-
CSI 11.7rCSI 13.5%PRS 87.7%
-
CSI 12.3rCSI 21.7%PRS 95.8%
-
CSI 12.4rCSI 24.5%PRS 94.2%
-
CSI 12.5rCSI 21.9%PRS 91.7%
-
CSI 12.6rCSI 47.2%PRS 91.1%
-
CSI 12.7rCSI 47.8%PRS 82.3%
-
CSI 13.7rCSI 45.0%PRS 84.7%
-
CSI 14.0rCSI 57.2%PRS 88.1%
-
CSI 14.3rCSI 46.1%PRS 90.8%
-
CSI 15.0rCSI 35.9%PRS 85.9%
-
CSI 15.4rCSI 52.9%PRS 83.7%
-
CSI 15.7rCSI 56.3%PRS 82.7%
-
CSI 16.3rCSI 47.3%PRS 87.5%
-
CSI 16.7rCSI 33.9%PRS 79.4%
-
CSI 18.0rCSI 47.8%PRS 83.8%
-
CSI 18.4rCSI 29.3%PRS 87.9%
-
CSI 19.1rCSI 51.1%PRS 90.3%
-
CSI 19.6rCSI 61.2%PRS 85.5%
-
CSI 19.7rCSI 34.1%PRS 90.2%
-
CSI 20.2rCSI 52.7%PRS 89.0%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 997652480
Symbol: FOG2_HUMAN
Name: Zinc finger protein ZFPM2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10438528
Title: hFOG-2, a novel zinc finger protein, binds the co-repressor mCtBP2 and modulates GATA-mediated activation.
PubMed ID: 10438528
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 23226341
Title: SUMOylation regulates the transcriptional repression activity of FOG-2 and its association with GATA-4.
PubMed ID: 23226341
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24549039
Title: Mutations in the FOG2/ZFPM2 gene are associated with anomalies of human testis determination.
PubMed ID: 24549039
DOI: 10.1093/hmg/ddu074
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 14517948
Title: Mutations of ZFPM2/FOG2 gene in sporadic cases of tetralogy of Fallot.
PubMed ID: 14517948
DOI: 10.1002/humu.10261
PubMed ID: 16103912
Title: Fog2 is required for normal diaphragm and lung development in mice and humans.
PubMed ID: 16103912
PubMed ID: 20807224
Title: New mutations in ZFPM2/FOG2 gene in tetralogy of Fallot and double outlet right ventricle.
PubMed ID: 20807224
Sequence Information:
- Length: 1151
- Mass: 128159
- Checksum: 680E31BA1D044C35
- Sequence:
MSRRKQSKPR QIKRPLEDAI EDEEEECPSE ETDIISKGDF PLEESFSTEF GPENLSCEEV EYFCNKGDDE GIQETAESDG DTQSEKPGQP GVETDDWDGP GELEVFQKDG ERKIQSRQQL PVGTTWGPFP GKMDLNNNSL KTKAQVPMVL TAGPKWLLDV TWQGVEDNKN NCIVYSKGGQ LWCTTTKAIS EGEELIAFVV DFDSRLQAAS QMTLTEGMYP ARLLDSIQLL PQQAAMASIL PTAIVNKDIF PCKSCGIWYR SERNLQAHLM YYCSGRQREA APVSEENEDS AHQISSLCPF PQCTKSFSNA RALEMHLNSH SGVKMEEFLP PGASLKCTVC SYTADSVINF HQHLFSHLTQ AAFRCNHCHF GFQTQRELLQ HQELHVPSGK LPRESDMEHS PSATEDSLQP ATDLLTRSEL PQSQKAMQTK DASSDTELDK CEKKTQLFLT NQRPEIQPTT NKQSFSYTKI KSEPSSPRLA SSPVQPNIGP SFPVGPFLSQ FSFPQDITMV PQASEILAKM SELVHRRLRH GSSSYPPVIY SPLMPKGATC FECNITFNNL DNYLVHKKHY CSSRWQQMAK SPEFPSVSEK MPEALSPNTG QTSINLLNPA AHSADPENPL LQTSCINSST VLDLIGPNGK GHDKDFSTQT KKLSTSSNND DKINGKPVDV KNPSVPLVDG ESDPNKTTCE ACNITFSRHE TYMVHKQYYC ATRHDPPLKR SASNKVPAMQ RTMRTRKRRK MYEMCLPEQE QRPPLVQQRF LDVANLNNPC TSTQEPTEGL GECYHPRCDI FPGIVSKHLE TSLTINKCVP VSKCDTTHSS VSCLEMDVPI DLSKKCLSQS ERTTTSPKRL LDYHECTVCK ISFNKVENYL AHKQNFCPVT AHQRNDLGQL DGKVFPNPES ERNSPDVSYE RSIIKCEKNG NLKQPSPNGN LFSSHLATLQ GLKVFSEAAQ LIATKEENRH LFLPQCLYPG AIKKAKGADQ LSPYYGIKPS DYISGSLVIH NTDIEQSRNA ENESPKGQAS SNGCAALKKD SLPLLPKNRG MVIVNGGLKQ DERPAANPQQ ENISQNPQHE DDHKSPSWIS ENPLAANENV SPGIPSAEEQ LSSIAKGVNG SSQAPTSGKY CRLCDIQFNN LSNFITHKKF YCSSHAAEHV K
Genular Protein ID: 979364591
Symbol: Q9NPQ0_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 79
- Mass: 8561
- Checksum: 6E8CDD7A7D4DB23A
- Sequence:
HKSPSWISEN PLAANENVSP GIPSAEEQLS SIAKGVNGSS QAPTSGKYCR LCDIQFNNLS NFITHKKFYC SSHAAEHVK