Details for: NUDT14
Gene ID: 256281
Gene Type: Protein-coding - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.
Symbol: NUDT14
Ensembl ID: ENSG00000183828
Description: nudix hydrolase 14
Selected Context(s): Overall
Cell Significance Landscape
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 13.84rCSI 14.5%PRS 77.44
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CSI 11.36rCSI 21.45%PRS 83.3
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CSI 8rCSI 12.2%PRS 70.84
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CSI 7.03rCSI 10.86%PRS 73.23
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CSI 6.2rCSI 14.14%PRS 68.77
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CSI 5.76rCSI 11.21%PRS 77.26
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CSI 5.28rCSI 4.65%PRS 62.62
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CSI 4.32rCSI 6.51%PRS 79.41
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CSI 3.97rCSI 4.59%PRS 65.74
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CSI 3.74rCSI 5.72%PRS 82.48
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CSI 3.65rCSI 8.07%PRS 73.07
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CSI 3.43rCSI 3.59%PRS 71.96
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CSI 3.39rCSI 18.21%PRS 83.05
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CSI 3.37rCSI 3.11%PRS 75.85
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CSI 3.34rCSI 3.29%PRS 76.84
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CSI 3.28rCSI 8.12%PRS 73.27
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CSI 3.28rCSI 13.04%PRS 83.22
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CSI 3.26rCSI 5.17%PRS 83.55
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CSI 3.22rCSI 7.18%PRS 81.86
-
CSI 3.2rCSI 4.96%PRS 79.15
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CSI 3.19rCSI 14.89%PRS 85.5
-
CSI 3.1rCSI 2.72%PRS 79.36
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CSI 3.07rCSI 2.9%PRS 73.38
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CSI 2.98rCSI 5.97%PRS 63.72
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CSI 2.88rCSI 3.01%PRS 73.93
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CSI 2.82rCSI 3.31%PRS 76.29
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CSI 2.8rCSI 3.25%PRS 79.41
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CSI 2.64rCSI 2.13%PRS 76.34
-
CSI 2.6rCSI 2.01%PRS 77.48
-
CSI 2.57rCSI 5.68%PRS 59.81
-
CSI 2.55rCSI 2.46%PRS 66.44
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CSI 2.5rCSI 2.16%PRS 78.66
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CSI 2.49rCSI 2.29%PRS 82.74
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CSI 2.48rCSI 3.79%PRS 78.38
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CSI 2.46rCSI 6.23%PRS 80
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CSI 2.44rCSI 4.39%PRS 67.25
-
CSI 2.41rCSI 1.9%PRS 61.81
-
CSI 2.37rCSI 2.48%PRS 71.35
-
CSI 2.36rCSI 3.22%PRS 74.69
-
CSI 2.35rCSI 5.18%PRS 78.25
-
CSI 2.31rCSI 2.97%PRS 77.85
-
CSI 2.24rCSI 2.77%PRS 71.63
-
CSI 2.18rCSI 1.72%PRS 80.39
-
CSI 2.16rCSI 7.69%PRS 79.9
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CSI 2.16rCSI 1.79%PRS 74.56
-
CSI 2.15rCSI 2.81%PRS 85.95
-
CSI 2.14rCSI 2.59%PRS 82.55
-
CSI 2.12rCSI 2.83%PRS 81.62
-
CSI 2.1rCSI 1.76%PRS 77.37
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CSI 2.06rCSI 3.57%PRS 64.97
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CSI 2.02rCSI 2.92%PRS 82.51
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CSI 2.02rCSI 2.1%PRS 79.04
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CSI 1.98rCSI 2.9%PRS 79.12
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CSI 1.97rCSI 3.2%PRS 69.72
-
CSI 1.83rCSI 3.23%PRS 70.21
-
CSI 1.83rCSI 1.62%PRS 72.1
-
CSI 1.82rCSI 2.44%PRS 73.24
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CSI 1.82rCSI 3.25%PRS 84.29
-
CSI 1.82rCSI 1.95%PRS 74.87
-
CSI 1.79rCSI 1.73%PRS 73.52
-
CSI 1.78rCSI 2.17%PRS 81.12
-
CSI 1.75rCSI 1.32%PRS 80.2
-
CSI 1.75rCSI 3.63%PRS 71.18
-
CSI 1.75rCSI 1.74%PRS 67.81
-
CSI 1.72rCSI 1.36%PRS 91.84
-
CSI 1.72rCSI 2.16%PRS 84.44
-
CSI 1.71rCSI 2.53%PRS 78.77
-
CSI 1.69rCSI 2.48%PRS 68.99
-
CSI 1.69rCSI 2.7%PRS 77.89
-
CSI 1.67rCSI 1.29%PRS 76.46
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CSI 1.63rCSI 2.03%PRS 75.56
-
CSI 1.59rCSI 2.56%PRS 74.62
-
CSI 1.57rCSI 2.19%PRS 72.72
-
CSI 1.57rCSI 2.09%PRS 80.23
-
CSI 1.56rCSI 2.93%PRS 83.99
-
CSI 1.54rCSI 2.09%PRS 83.91
-
CSI 1.53rCSI 10.47%PRS 82.95
-
CSI 1.51rCSI 1.7%PRS 88.48
-
CSI 1.51rCSI 1.37%PRS 71.82
-
CSI 1.44rCSI 4.51%PRS 57.37
-
CSI 1.37rCSI 2.01%PRS 84.43
-
CSI 1.35rCSI 2.22%PRS 78.96
-
CSI 1.29rCSI 3.16%PRS 66.92
-
CSI 1.24rCSI 1.69%PRS 65.53
-
CSI 1.23rCSI 2.93%PRS 81.16
-
CSI 1.15rCSI 2.36%PRS 62.13
-
CSI 1.11rCSI 1.78%PRS 63.72
-
CSI 1.06rCSI 1.87%PRS 54.68
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CSI 1.01rCSI 1.55%PRS 84.34
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CSI 0.92rCSI 3.12%PRS 74.03
-
CSI 0.86rCSI 3.02%PRS 83.62
-
CSI 0.86rCSI 3.43%PRS 84.61
-
CSI 0.78rCSI 1.34%PRS 81.48
-
CSI 0.76rCSI 4.72%PRS 93.21
-
CSI 0.62rCSI 2.7%PRS 83.18
-
CSI 0.58rCSI 2.73%PRS 85.53
-
CSI 0.56rCSI 3.95%PRS 82.06
-
CSI 0.5rCSI 3.97%PRS 85.21
-
CSI 0.41rCSI 2.21%PRS 84.35
-
CSI 0.4rCSI 3.15%PRS 81.34
-
CSI 0.2rCSI 1.9%PRS 85.9%
-
CSI 0.3rCSI 6.2%PRS 84.5%
-
CSI 0.4rCSI 3.2%PRS 81.3%
-
CSI 0.4rCSI 2.2%PRS 84.4%
-
CSI 0.5rCSI 4.0%PRS 85.2%
-
CSI 0.6rCSI 4.0%PRS 82.1%
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CSI 0.6rCSI 2.7%PRS 85.5%
-
CSI 0.6rCSI 2.7%PRS 83.2%
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CSI 0.8rCSI 4.7%PRS 93.2%
-
CSI 0.8rCSI 1.3%PRS 81.5%
-
CSI 0.9rCSI 3.4%PRS 84.6%
-
CSI 0.9rCSI 3.0%PRS 83.6%
-
CSI 0.9rCSI 3.1%PRS 74.0%
-
CSI 1.0rCSI 1.6%PRS 84.3%
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CSI 1.1rCSI 1.9%PRS 54.7%
-
CSI 1.1rCSI 1.8%PRS 63.7%
-
CSI 1.2rCSI 2.4%PRS 62.1%
-
CSI 1.2rCSI 2.9%PRS 81.2%
-
CSI 1.2rCSI 1.7%PRS 65.5%
-
CSI 1.3rCSI 3.2%PRS 66.9%
-
CSI 1.4rCSI 2.2%PRS 79.0%
-
CSI 1.4rCSI 2.0%PRS 84.4%
-
CSI 1.4rCSI 4.5%PRS 57.4%
-
CSI 1.5rCSI 1.4%PRS 71.8%
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CSI 1.5rCSI 1.7%PRS 88.5%
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CSI 1.5rCSI 10.5%PRS 83.0%
-
CSI 1.5rCSI 2.1%PRS 83.9%
-
CSI 1.6rCSI 2.9%PRS 84.0%
-
CSI 1.6rCSI 2.1%PRS 80.2%
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CSI 1.6rCSI 2.2%PRS 72.7%
-
CSI 1.6rCSI 2.6%PRS 74.6%
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CSI 1.6rCSI 2.0%PRS 75.6%
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CSI 1.7rCSI 1.3%PRS 76.5%
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CSI 1.7rCSI 2.7%PRS 77.9%
-
CSI 1.7rCSI 2.5%PRS 69.0%
-
CSI 1.7rCSI 2.5%PRS 78.8%
-
CSI 1.7rCSI 2.2%PRS 84.4%
-
CSI 1.7rCSI 1.4%PRS 91.8%
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CSI 1.8rCSI 1.7%PRS 67.8%
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CSI 1.8rCSI 3.6%PRS 71.2%
-
CSI 1.8rCSI 1.3%PRS 80.2%
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CSI 1.8rCSI 2.2%PRS 81.1%
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CSI 1.8rCSI 1.7%PRS 73.5%
-
CSI 1.8rCSI 2.0%PRS 74.9%
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CSI 1.8rCSI 3.3%PRS 84.3%
-
CSI 1.8rCSI 2.4%PRS 73.2%
-
CSI 1.8rCSI 1.6%PRS 72.1%
-
CSI 1.8rCSI 3.2%PRS 70.2%
-
CSI 2.0rCSI 3.2%PRS 69.7%
-
CSI 2.0rCSI 2.9%PRS 79.1%
-
CSI 2.0rCSI 2.1%PRS 79.0%
-
CSI 2.0rCSI 2.9%PRS 82.5%
-
CSI 2.1rCSI 3.6%PRS 65.0%
-
CSI 2.1rCSI 1.8%PRS 77.4%
-
CSI 2.1rCSI 2.8%PRS 81.6%
-
CSI 2.1rCSI 2.6%PRS 82.6%
-
CSI 2.2rCSI 2.8%PRS 86.0%
-
CSI 2.2rCSI 1.8%PRS 74.6%
-
CSI 2.2rCSI 7.7%PRS 79.9%
-
CSI 2.2rCSI 1.7%PRS 80.4%
-
CSI 2.2rCSI 2.8%PRS 71.6%
-
CSI 2.3rCSI 3.0%PRS 77.9%
-
CSI 2.4rCSI 5.2%PRS 78.3%
-
CSI 2.4rCSI 3.2%PRS 74.7%
-
CSI 2.4rCSI 2.5%PRS 71.4%
-
CSI 2.4rCSI 1.9%PRS 61.8%
-
CSI 2.4rCSI 4.4%PRS 67.3%
-
CSI 2.5rCSI 6.2%PRS 80.0%
-
CSI 2.5rCSI 3.8%PRS 78.4%
-
CSI 2.5rCSI 2.3%PRS 82.7%
-
CSI 2.5rCSI 2.2%PRS 78.7%
-
CSI 2.6rCSI 2.5%PRS 66.4%
-
CSI 2.6rCSI 5.7%PRS 59.8%
-
CSI 2.6rCSI 2.0%PRS 77.5%
-
CSI 2.6rCSI 2.1%PRS 76.3%
-
CSI 2.8rCSI 3.3%PRS 79.4%
-
CSI 2.8rCSI 3.3%PRS 76.3%
-
CSI 2.9rCSI 3.0%PRS 73.9%
-
CSI 3.0rCSI 6.0%PRS 63.7%
-
CSI 3.1rCSI 2.9%PRS 73.4%
-
CSI 3.1rCSI 2.7%PRS 79.4%
-
CSI 3.2rCSI 14.9%PRS 85.5%
-
CSI 3.2rCSI 5.0%PRS 79.2%
-
CSI 3.2rCSI 7.2%PRS 81.9%
-
CSI 3.3rCSI 5.2%PRS 83.6%
-
CSI 3.3rCSI 13.0%PRS 83.2%
-
CSI 3.3rCSI 8.1%PRS 73.3%
-
CSI 3.3rCSI 3.3%PRS 76.8%
-
CSI 3.4rCSI 3.1%PRS 75.9%
-
CSI 3.4rCSI 18.2%PRS 83.1%
-
CSI 3.4rCSI 3.6%PRS 72.0%
-
CSI 3.7rCSI 8.1%PRS 73.1%
-
CSI 3.7rCSI 5.7%PRS 82.5%
-
CSI 4.0rCSI 4.6%PRS 65.7%
-
CSI 4.3rCSI 6.5%PRS 79.4%
-
CSI 5.3rCSI 4.7%PRS 62.6%
-
CSI 5.8rCSI 11.2%PRS 77.3%
-
CSI 6.2rCSI 14.1%PRS 68.8%
-
CSI 7.0rCSI 10.9%PRS 73.2%
-
CSI 8.0rCSI 12.2%PRS 70.8%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 847578406
Symbol: NUD14_HUMAN
Name: Uridine diphosphate glucose pyrophosphatase NUDT14
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10662552
Title: Characterization, chromosomal localization, and the complete 30-kb DNA sequence of the human Jagged2 (JAG2) gene.
PubMed ID: 10662552
PubMed ID: 12429023
Title: Cloning, expression and characterization of a mammalian Nudix hydrolase-like enzyme that cleaves the pyrophosphate bond of UDP-glucose.
PubMed ID: 12429023
DOI: 10.1042/bj20021140
PubMed ID: 12508121
Title: The DNA sequence and analysis of human chromosome 14.
PubMed ID: 12508121
DOI: 10.1038/nature01348
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 222
- Mass: 24118
- Checksum: FB1DFA40A67E72B6
- Sequence:
MERIEGASVG RCAASPYLRP LTLHYRQNGA QKSWDFMKTH DSVTVLLFNS SRRSLVLVKQ FRPAVYAGEV ERRFPGSLAA VDQDGPRELQ PALPGSAGVT VELCAGLVDQ PGLSLEEVAC KEAWEECGYH LAPSDLRRVA TYWSGVGLTG SRQTMFYTEV TDAQRSGPGG GLVEEGELIE VVHLPLEGAQ AFADDPDIPK TLGVIFGVSW FLSQVAPNLD LQ
Genular Protein ID: 1317333600
Symbol: B3KXY7_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11181995
Sequence Information:
- Length: 149
- Mass: 16369
- Checksum: DFB48F9E3D770C54
- Sequence:
MERIEGASVG RCAASPYLRP LTLHYRQNGA QKSWDFMKTH DSVTVLLFNS SRRSLVLVKQ FRPAVYAGEV ERRFPGSLAA VDQDGPRELQ PALPGSAGVT VELCAGLVDQ PGLSLEEVAC KEAWEECGYH LAPSDLRRVA TYWDATMGS