Details for: ATP5MGP3

Gene ID: 53409

Symbol: ATP5MGP3

Ensembl ID: ENSG00000249256

Description: ATP synthase membrane subunit g pseudogene 3

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.4896
    Cell Significance Index: 6.9700
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 0.1796
    Cell Significance Index: 5.2900
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.1592
    Cell Significance Index: 2.3500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.1158
    Cell Significance Index: 1.5800
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.1009
    Cell Significance Index: 1.6000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0834
    Cell Significance Index: 3.8900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0552
    Cell Significance Index: 3.4800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0167
    Cell Significance Index: 2.8600
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: 0.0085
    Cell Significance Index: 0.1100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0045
    Cell Significance Index: 0.9100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.0003
    Cell Significance Index: 0.0300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0077
    Cell Significance Index: -0.4000
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0288
    Cell Significance Index: -0.5700
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0300
    Cell Significance Index: -1.0500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0302
    Cell Significance Index: -1.3700
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0310
    Cell Significance Index: -0.6700
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0316
    Cell Significance Index: -1.0300
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0327
    Cell Significance Index: -1.0400
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0327
    Cell Significance Index: -0.6900
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0373
    Cell Significance Index: -0.9300
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.0432
    Cell Significance Index: -1.0800
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.0442
    Cell Significance Index: -0.8700
  • Cell Name: melanocyte (CL0000148)
    Fold Change: -0.0469
    Cell Significance Index: -0.4400
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0478
    Cell Significance Index: -0.9600
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.0527
    Cell Significance Index: -1.0500
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.0528
    Cell Significance Index: -1.1000
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: -0.0552
    Cell Significance Index: -0.6500
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.0564
    Cell Significance Index: -0.9800
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.0640
    Cell Significance Index: -2.3500
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.0841
    Cell Significance Index: -1.4500
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.0851
    Cell Significance Index: -1.0000
  • Cell Name: regulatory T cell (CL0000815)
    Fold Change: -0.0862
    Cell Significance Index: -1.0000
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: -0.0908
    Cell Significance Index: -0.8200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0915
    Cell Significance Index: -2.4900
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.0946
    Cell Significance Index: -1.3600
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: -0.0946
    Cell Significance Index: -0.9600
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: -0.0954
    Cell Significance Index: -0.9300
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0977
    Cell Significance Index: -2.4900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0980
    Cell Significance Index: -1.6800
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: -0.1126
    Cell Significance Index: -0.9500
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: -0.1153
    Cell Significance Index: -1.4400
  • Cell Name: intermediate monocyte (CL0002393)
    Fold Change: -0.1159
    Cell Significance Index: -1.0800
  • Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell (CL0000895)
    Fold Change: -0.1165
    Cell Significance Index: -1.0100
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.1219
    Cell Significance Index: -1.4500
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.1248
    Cell Significance Index: -2.1200
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.1273
    Cell Significance Index: -2.6400
  • Cell Name: retina horizontal cell (CL0000745)
    Fold Change: -0.1339
    Cell Significance Index: -1.6800
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: -0.1347
    Cell Significance Index: -1.8500
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.1376
    Cell Significance Index: -1.8000
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: -0.1379
    Cell Significance Index: -1.4400
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: -0.1404
    Cell Significance Index: -2.4000
  • Cell Name: chondrocyte (CL0000138)
    Fold Change: -0.1414
    Cell Significance Index: -1.6300
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: -0.1441
    Cell Significance Index: -1.5600
  • Cell Name: erythroid lineage cell (CL0000764)
    Fold Change: -0.1451
    Cell Significance Index: -1.6000
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.1502
    Cell Significance Index: -1.7900
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: -0.1533
    Cell Significance Index: -1.9700
  • Cell Name: mast cell (CL0000097)
    Fold Change: -0.1550
    Cell Significance Index: -2.0400
  • Cell Name: pericyte (CL0000669)
    Fold Change: -0.1551
    Cell Significance Index: -1.8600
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.1562
    Cell Significance Index: -2.3400
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.1573
    Cell Significance Index: -1.8000
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.1583
    Cell Significance Index: -1.6700
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.1586
    Cell Significance Index: -2.0700
  • Cell Name: amacrine cell (CL0000561)
    Fold Change: -0.1589
    Cell Significance Index: -1.9900
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -0.1600
    Cell Significance Index: -1.9400
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: -0.1600
    Cell Significance Index: -2.1000
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: -0.1611
    Cell Significance Index: -1.8200
  • Cell Name: neutrophil (CL0000775)
    Fold Change: -0.1625
    Cell Significance Index: -2.0300
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: -0.1629
    Cell Significance Index: -1.9700
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: -0.1634
    Cell Significance Index: -1.4400
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.1635
    Cell Significance Index: -2.0100
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: -0.1637
    Cell Significance Index: -1.8500
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: -0.1639
    Cell Significance Index: -2.1400
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: -0.1649
    Cell Significance Index: -1.9600
  • Cell Name: pulmonary alveolar type 2 cell (CL0002063)
    Fold Change: -0.1650
    Cell Significance Index: -1.3700
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: -0.1673
    Cell Significance Index: -1.6900
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.1677
    Cell Significance Index: -1.9800
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: -0.1683
    Cell Significance Index: -1.9600
  • Cell Name: endothelial cell of artery (CL1000413)
    Fold Change: -0.1689
    Cell Significance Index: -1.7800
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: -0.1692
    Cell Significance Index: -1.9400
  • Cell Name: interneuron (CL0000099)
    Fold Change: -0.1695
    Cell Significance Index: -1.9800
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: -0.1700
    Cell Significance Index: -1.8600
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: -0.1714
    Cell Significance Index: -1.9900
  • Cell Name: myofibroblast cell (CL0000186)
    Fold Change: -0.1717
    Cell Significance Index: -1.8000
  • Cell Name: acinar cell (CL0000622)
    Fold Change: -0.1720
    Cell Significance Index: -2.1600
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: -0.1724
    Cell Significance Index: -1.9300
  • Cell Name: retinal pigment epithelial cell (CL0002586)
    Fold Change: -0.1739
    Cell Significance Index: -1.8700
  • Cell Name: plasma cell (CL0000786)
    Fold Change: -0.1745
    Cell Significance Index: -1.9500
  • Cell Name: mesothelial cell (CL0000077)
    Fold Change: -0.1760
    Cell Significance Index: -2.1400
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.1781
    Cell Significance Index: -1.4700
  • Cell Name: granulocyte (CL0000094)
    Fold Change: -0.1782
    Cell Significance Index: -2.1500
  • Cell Name: B cell (CL0000236)
    Fold Change: -0.1794
    Cell Significance Index: -2.1200
  • Cell Name: monocyte (CL0000576)
    Fold Change: -0.1799
    Cell Significance Index: -2.0700
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: -0.1800
    Cell Significance Index: -2.1900
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: -0.1819
    Cell Significance Index: -1.7600
  • Cell Name: kidney loop of Henle epithelial cell (CL1000909)
    Fold Change: -0.1835
    Cell Significance Index: -1.7100
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: -0.1842
    Cell Significance Index: -2.0400
  • Cell Name: conventional dendritic cell (CL0000990)
    Fold Change: -0.1845
    Cell Significance Index: -2.1800
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: -0.1856
    Cell Significance Index: -1.9500
  • Cell Name: memory B cell (CL0000787)
    Fold Change: -0.1861
    Cell Significance Index: -1.9800
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.1865
    Cell Significance Index: -2.0000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** ATP5MGP3 is a pseudogene, meaning it is a non-functional copy of a gene that has undergone mutations and inactivation. However, unlike traditional pseudogenes, ATP5MGP3 is significantly expressed in various human tissues, with expression levels ranging from high to low. This expression pattern is not limited to specific tissues, as ATP5MGP3 has been detected in multiple cell types, including epithelial cells, muscle cells, and neuronal cells. The expression of ATP5MGP3 is often correlated with the presence of functional ATP synthase genes, suggesting a possible functional overlap between the two. **Pathways and Functions:** The ATP5MGP3 gene is involved in several cellular pathways, including energy metabolism, cell signaling, and transcriptional regulation. While the exact mechanisms of ATP5MGP3 are not fully understood, its expression in various tissues suggests a role in maintaining cellular homeostasis. One possible function of ATP5MGP3 is to regulate the expression of other genes involved in energy metabolism, such as the ATP synthase gene family. Additionally, ATP5MGP3 may interact with other signaling pathways, including the PI3K/AKT and MAPK/ERK pathways, to modulate cell growth, differentiation, and survival. **Clinical Significance:** The clinical significance of ATP5MGP3 is an area of ongoing research. Given its expression in multiple tissues, ATP5MGP3 may play a role in various human diseases, including cancer, neurodegenerative disorders, and metabolic disorders. For example, alterations in ATP5MGP3 expression have been linked to the development of certain types of cancer, including breast and lung cancer. Additionally, ATP5MGP3 may be involved in the pathogenesis of neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease, where energy metabolism and cell signaling pathways are disrupted. In conclusion, the ATP5MGP3 gene is a pseudogene with multifaceted roles in human tissues, exhibiting significant expression levels in multiple cell types. Further research is needed to fully understand the mechanisms of ATP5MGP3 and its clinical significance in human diseases. However, the existing evidence suggests that ATP5MGP3 may play a crucial role in maintaining cellular homeostasis and regulating energy metabolism, with implications for the diagnosis and treatment of various human diseases.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.