Details for: RNVU1 7

Gene ID: 26864

Symbol: RNVU1 7

Ensembl ID: ENSG00000206585

Description: RNA, variant U1 small nuclear 7

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: adipocyte (CL0000136)
    Fold Change: 0.2858
    Cell Significance Index: 3.8100
  • Cell Name: granulocyte (CL0000094)
    Fold Change: 0.2801
    Cell Significance Index: 3.3800
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: 0.2582
    Cell Significance Index: 2.2800
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: 0.1246
    Cell Significance Index: 1.6100
  • Cell Name: stem cell (CL0000034)
    Fold Change: 0.0715
    Cell Significance Index: 0.5200
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: 0.0552
    Cell Significance Index: 0.5600
  • Cell Name: muscle cell (CL0000187)
    Fold Change: 0.0481
    Cell Significance Index: 0.4600
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 0.0404
    Cell Significance Index: 0.6900
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: 0.0356
    Cell Significance Index: 0.3600
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0333
    Cell Significance Index: 0.9600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0314
    Cell Significance Index: 0.6800
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: 0.0224
    Cell Significance Index: 0.4500
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: 0.0141
    Cell Significance Index: 0.1300
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: 0.0130
    Cell Significance Index: 0.1100
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 0.0088
    Cell Significance Index: 0.2200
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0065
    Cell Significance Index: -0.2100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0066
    Cell Significance Index: -1.3300
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.0077
    Cell Significance Index: -0.1500
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0078
    Cell Significance Index: -0.1900
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0084
    Cell Significance Index: -0.1700
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.0087
    Cell Significance Index: -0.1700
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0087
    Cell Significance Index: -0.1800
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0091
    Cell Significance Index: -0.2000
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0109
    Cell Significance Index: -0.1600
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: -0.0116
    Cell Significance Index: -0.1500
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: -0.0123
    Cell Significance Index: -0.1200
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0125
    Cell Significance Index: -0.4000
  • Cell Name: regulatory T cell (CL0000815)
    Fold Change: -0.0134
    Cell Significance Index: -0.1600
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: -0.0193
    Cell Significance Index: -0.2000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0213
    Cell Significance Index: -0.2900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0221
    Cell Significance Index: -1.0000
  • Cell Name: naive B cell (CL0000788)
    Fold Change: -0.0259
    Cell Significance Index: -0.2700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0260
    Cell Significance Index: -1.3500
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: -0.0279
    Cell Significance Index: -0.2700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0359
    Cell Significance Index: -1.2600
  • Cell Name: CD8-positive, alpha-beta cytotoxic T cell (CL0000794)
    Fold Change: -0.0372
    Cell Significance Index: -0.3000
  • Cell Name: naive regulatory T cell (CL0002677)
    Fold Change: -0.0397
    Cell Significance Index: -0.3600
  • Cell Name: vascular associated smooth muscle cell (CL0000359)
    Fold Change: -0.0405
    Cell Significance Index: -0.4300
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: -0.0473
    Cell Significance Index: -0.4400
  • Cell Name: memory B cell (CL0000787)
    Fold Change: -0.0545
    Cell Significance Index: -0.5800
  • Cell Name: elicited macrophage (CL0000861)
    Fold Change: -0.0561
    Cell Significance Index: -0.4900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0583
    Cell Significance Index: -2.7200
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.0629
    Cell Significance Index: -2.3100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0643
    Cell Significance Index: -1.7500
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: -0.0643
    Cell Significance Index: -0.7300
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.0680
    Cell Significance Index: -0.8000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0693
    Cell Significance Index: -2.2200
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: -0.0786
    Cell Significance Index: -0.8700
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.0790
    Cell Significance Index: -1.9700
  • Cell Name: B cell (CL0000236)
    Fold Change: -0.0804
    Cell Significance Index: -0.9500
  • Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
    Fold Change: -0.0806
    Cell Significance Index: -0.8400
  • Cell Name: non-classical monocyte (CL0000875)
    Fold Change: -0.0826
    Cell Significance Index: -0.9200
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.0864
    Cell Significance Index: -1.1300
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.0974
    Cell Significance Index: -1.4600
  • Cell Name: monocyte (CL0000576)
    Fold Change: -0.0991
    Cell Significance Index: -1.1400
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: -0.1027
    Cell Significance Index: -1.2100
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: -0.1049
    Cell Significance Index: -1.3100
  • Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
    Fold Change: -0.1076
    Cell Significance Index: -1.0200
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: -0.1082
    Cell Significance Index: -1.4200
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.1112
    Cell Significance Index: -1.3300
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.1117
    Cell Significance Index: -1.4100
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: -0.1134
    Cell Significance Index: -1.3800
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: -0.1137
    Cell Significance Index: -1.3400
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.1146
    Cell Significance Index: -1.9300
  • Cell Name: plasma cell (CL0000786)
    Fold Change: -0.1155
    Cell Significance Index: -1.2900
  • Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
    Fold Change: -0.1181
    Cell Significance Index: -1.1100
  • Cell Name: conventional dendritic cell (CL0000990)
    Fold Change: -0.1185
    Cell Significance Index: -1.4000
  • Cell Name: vein endothelial cell (CL0002543)
    Fold Change: -0.1208
    Cell Significance Index: -1.3100
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.1223
    Cell Significance Index: -1.4000
  • Cell Name: retinal pigment epithelial cell (CL0002586)
    Fold Change: -0.1237
    Cell Significance Index: -1.3300
  • Cell Name: capillary endothelial cell (CL0002144)
    Fold Change: -0.1241
    Cell Significance Index: -1.4100
  • Cell Name: pulmonary alveolar type 1 cell (CL0002062)
    Fold Change: -0.1275
    Cell Significance Index: -1.4000
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.1278
    Cell Significance Index: -1.3700
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.1285
    Cell Significance Index: -1.4000
  • Cell Name: lung macrophage (CL1001603)
    Fold Change: -0.1291
    Cell Significance Index: -1.4100
  • Cell Name: stromal cell (CL0000499)
    Fold Change: -0.1292
    Cell Significance Index: -1.3200
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.1293
    Cell Significance Index: -1.8400
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: -0.1295
    Cell Significance Index: -1.4400
  • Cell Name: bronchus fibroblast of lung (CL2000093)
    Fold Change: -0.1302
    Cell Significance Index: -1.3900
  • Cell Name: alveolar adventitial fibroblast (CL4028006)
    Fold Change: -0.1346
    Cell Significance Index: -1.5000
  • Cell Name: tracheobronchial smooth muscle cell (CL0019019)
    Fold Change: -0.1350
    Cell Significance Index: -1.3900
  • Cell Name: lung neuroendocrine cell (CL1000223)
    Fold Change: -0.1351
    Cell Significance Index: -1.3400
  • Cell Name: pulmonary artery endothelial cell (CL1001568)
    Fold Change: -0.1366
    Cell Significance Index: -1.4600
  • Cell Name: alveolar type 1 fibroblast cell (CL4028004)
    Fold Change: -0.1370
    Cell Significance Index: -1.4500
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: -0.1398
    Cell Significance Index: -1.9200
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: -0.1404
    Cell Significance Index: -1.2900
  • Cell Name: pulmonary alveolar type 2 cell (CL0002063)
    Fold Change: -0.1451
    Cell Significance Index: -1.2000
  • Cell Name: effector memory CD8-positive, alpha-beta T cell (CL0000913)
    Fold Change: -0.1453
    Cell Significance Index: -1.1300
  • Cell Name: mast cell (CL0000097)
    Fold Change: -0.1474
    Cell Significance Index: -1.9400
  • Cell Name: neutrophil (CL0000775)
    Fold Change: -0.1481
    Cell Significance Index: -1.8500
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.1498
    Cell Significance Index: -1.4200
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.1502
    Cell Significance Index: -1.9600
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: -0.1532
    Cell Significance Index: -2.0000
  • Cell Name: alternatively activated macrophage (CL0000890)
    Fold Change: -0.1546
    Cell Significance Index: -1.4400
  • Cell Name: neuroblast (sensu Nematoda and Protostomia) (CL0000338)
    Fold Change: -0.1551
    Cell Significance Index: -1.4100
  • Cell Name: macrophage (CL0000235)
    Fold Change: -0.1567
    Cell Significance Index: -1.6000
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.1578
    Cell Significance Index: -1.9400
  • Cell Name: mesothelial cell (CL0000077)
    Fold Change: -0.1612
    Cell Significance Index: -1.9600
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: -0.1632
    Cell Significance Index: -1.9600
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: -0.1633
    Cell Significance Index: -1.5800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** RNVU1 7 is a member of the U1 small nuclear ribonucleoprotein (snRNP) family, which is essential for the recognition and binding of pre-mRNA 5'-splice sites. This gene is characterized by its ability to regulate mRNA splicing, a process that involves the removal of introns and the joining of exons to produce a mature mRNA molecule. RNVU1 7 is specifically expressed in cells that require precise control over gene expression, such as immune cells and epithelial cells. **Pathways and Functions:** The RNVU1 7 gene is involved in several key pathways, including mRNA 5'-splice site recognition, pre-mRNA 5'-splice site binding, and U1 snRNP. These pathways are essential for the accurate expression of genes, as they ensure that the correct exons are spliced together to produce a mature mRNA molecule. The RNVU1 7 gene plays a critical role in these pathways by recognizing and binding to pre-mRNA 5'-splice sites, thereby facilitating the splicing process. **Clinical Significance:** RNVU1 7 has significant clinical implications, particularly in the context of immune function and tissue homeostasis. Dysregulation of the RNVU1 7 gene has been linked to various diseases, including autoimmune disorders and cancer. For example, alterations in the expression of RNVU1 7 have been observed in patients with rheumatoid arthritis, a chronic autoimmune disease characterized by inflammation and tissue damage. Additionally, RNVU1 7 has been implicated in the development of certain types of cancer, such as colon cancer, where its dysregulation can lead to uncontrolled cell growth and tumor formation. Furthermore, RNVU1 7 has been identified as a potential biomarker for various diseases, including cancer and autoimmune disorders. Its expression levels can be used to diagnose disease and monitor treatment response. For instance, studies have shown that RNVU1 7 expression levels are elevated in patients with colon cancer, making it a promising biomarker for early detection and diagnosis. In conclusion, the RNVU1 7 gene is a critical regulator of mRNA splicing, with significant implications for immune function and tissue homeostasis. Its dysregulation has been linked to various diseases, including autoimmune disorders and cancer, highlighting the need for further research into its role in human health and disease.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.