**Key characteristics:**
- HSPA8P1 is a pseudogene, meaning it is a gene that is not directly transcribed but is produced from a different gene through a process called alternative splicing.
- It is located on chromosome 19p13.3.
- It is a large gene, with a total length of approximately 10.5 kb.
- It contains 13 exons and 12 introns.
- It is expressed in a variety of cell types, suggesting that it plays a role in multiple biological processes.
**Pathways and functions:**
- HSPA8P1 is involved in the regulation of inflammation.
- It is expressed in immune cells, where it is thought to play a role in the regulation of immune responses.
- It is also expressed in non-immune cells, where it is thought to regulate cell migration and differentiation.
- Studies have shown that HSPA8P1 can interact with other heat shock proteins, such as HSP70 and HSP90, which are also involved in inflammation.
- This interaction is thought to be important for the regulation of inflammation.
**Clinical significance:**
- Mutations in the HSPA8P1 gene have been linked to several human diseases, including rheumatoid arthritis, atherosclerosis, and cancer.
- These mutations can disrupt the normal function of HSPA8P1, leading to the development of these diseases.
- Therefore, understanding the role of HSPA8P1 in inflammation and cell migration may lead to the development of new treatments for these diseases.
Disclaimer: This summary is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.
