Details for: RPSAP14

Gene ID: 3924

Symbol: RPSAP14

Ensembl ID: ENSG00000233984

Description: ribosomal protein SA pseudogene 14

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: 0.0835
    Cell Significance Index: 0.9100
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 0.0704
    Cell Significance Index: 1.0300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.0325
    Cell Significance Index: 0.8700
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.0232
    Cell Significance Index: 0.2400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0043
    Cell Significance Index: 0.7300
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.0018
    Cell Significance Index: 0.0400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0006
    Cell Significance Index: 0.0400
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: -0.0047
    Cell Significance Index: -0.0600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0086
    Cell Significance Index: -0.9800
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: -0.0120
    Cell Significance Index: -0.1400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0242
    Cell Significance Index: -1.1300
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: -0.0248
    Cell Significance Index: -0.2800
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.0354
    Cell Significance Index: -1.3000
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0359
    Cell Significance Index: -0.5300
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: -0.0360
    Cell Significance Index: -0.4600
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.0427
    Cell Significance Index: -0.7400
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.0452
    Cell Significance Index: -0.5700
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: -0.0456
    Cell Significance Index: -0.6400
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: -0.0485
    Cell Significance Index: -0.5900
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.0511
    Cell Significance Index: -0.7100
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: -0.0536
    Cell Significance Index: -0.5100
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.0583
    Cell Significance Index: -0.9800
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: -0.0638
    Cell Significance Index: -1.0900
  • Cell Name: CD8-positive, alpha-beta thymocyte (CL0000811)
    Fold Change: -0.0805
    Cell Significance Index: -0.7500
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.0814
    Cell Significance Index: -0.9700
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: -0.0823
    Cell Significance Index: -1.1300
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: -0.0833
    Cell Significance Index: -0.9900
  • Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
    Fold Change: -0.0835
    Cell Significance Index: -0.7900
  • Cell Name: mesothelial cell (CL0000077)
    Fold Change: -0.0839
    Cell Significance Index: -1.0200
  • Cell Name: mural cell (CL0008034)
    Fold Change: -0.0840
    Cell Significance Index: -1.0200
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.0903
    Cell Significance Index: -1.0800
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: -0.0915
    Cell Significance Index: -0.9700
  • Cell Name: myofibroblast cell (CL0000186)
    Fold Change: -0.0925
    Cell Significance Index: -0.9700
  • Cell Name: cell of skeletal muscle (CL0000188)
    Fold Change: -0.0929
    Cell Significance Index: -1.1900
  • Cell Name: acinar cell (CL0000622)
    Fold Change: -0.0931
    Cell Significance Index: -1.1700
  • Cell Name: pericyte (CL0000669)
    Fold Change: -0.0947
    Cell Significance Index: -1.1400
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: -0.0958
    Cell Significance Index: -1.2500
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.0970
    Cell Significance Index: -1.1100
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: -0.0977
    Cell Significance Index: -1.1100
  • Cell Name: mast cell (CL0000097)
    Fold Change: -0.0988
    Cell Significance Index: -1.3000
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: -0.0989
    Cell Significance Index: -1.1000
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.1026
    Cell Significance Index: -1.1000
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: -0.1028
    Cell Significance Index: -1.1900
  • Cell Name: amacrine cell (CL0000561)
    Fold Change: -0.1030
    Cell Significance Index: -1.2900
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -0.1031
    Cell Significance Index: -1.2500
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: -0.1033
    Cell Significance Index: -1.2000
  • Cell Name: ganglion interneuron (CL0000397)
    Fold Change: -0.1038
    Cell Significance Index: -0.8500
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: -0.1042
    Cell Significance Index: -1.2600
  • Cell Name: stromal cell (CL0000499)
    Fold Change: -0.1057
    Cell Significance Index: -1.0800
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: -0.1075
    Cell Significance Index: -1.2500
  • Cell Name: granule cell (CL0000120)
    Fold Change: -0.1080
    Cell Significance Index: -1.2300
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.1091
    Cell Significance Index: -1.4500
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: -0.1100
    Cell Significance Index: -1.1500
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: -0.1107
    Cell Significance Index: -1.4300
  • Cell Name: memory B cell (CL0000787)
    Fold Change: -0.1109
    Cell Significance Index: -1.1800
  • Cell Name: plasma cell (CL0000786)
    Fold Change: -0.1128
    Cell Significance Index: -1.2600
  • Cell Name: chondrocyte (CL0000138)
    Fold Change: -0.1128
    Cell Significance Index: -1.3000
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.1131
    Cell Significance Index: -1.3900
  • Cell Name: neuronal brush cell (CL0000555)
    Fold Change: -0.1161
    Cell Significance Index: -1.2600
  • Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
    Fold Change: -0.1161
    Cell Significance Index: -1.1700
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: -0.1171
    Cell Significance Index: -1.3000
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: -0.1178
    Cell Significance Index: -1.4700
  • Cell Name: vascular associated smooth muscle cell (CL0000359)
    Fold Change: -0.1185
    Cell Significance Index: -1.2600
  • Cell Name: mature T cell (CL0002419)
    Fold Change: -0.1191
    Cell Significance Index: -0.8600
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.1194
    Cell Significance Index: -1.2600
  • Cell Name: retina horizontal cell (CL0000745)
    Fold Change: -0.1195
    Cell Significance Index: -1.5000
  • Cell Name: blood vessel endothelial cell (CL0000071)
    Fold Change: -0.1197
    Cell Significance Index: -1.3000
  • Cell Name: OFF-bipolar cell (CL0000750)
    Fold Change: -0.1198
    Cell Significance Index: -1.0600
  • Cell Name: pulmonary alveolar type 2 cell (CL0002063)
    Fold Change: -0.1209
    Cell Significance Index: -1.0000
  • Cell Name: vein endothelial cell (CL0002543)
    Fold Change: -0.1213
    Cell Significance Index: -1.3100
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.1240
    Cell Significance Index: -1.4800
  • Cell Name: B cell (CL0000236)
    Fold Change: -0.1240
    Cell Significance Index: -1.4700
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: -0.1282
    Cell Significance Index: -1.2400
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.1308
    Cell Significance Index: -1.2400
  • Cell Name: macrophage (CL0000235)
    Fold Change: -0.1313
    Cell Significance Index: -1.3400
  • Cell Name: alternatively activated macrophage (CL0000890)
    Fold Change: -0.1336
    Cell Significance Index: -1.2400
  • Cell Name: fibroblast (CL0000057)
    Fold Change: -0.1342
    Cell Significance Index: -1.2600
  • Cell Name: kidney loop of Henle epithelial cell (CL1000909)
    Fold Change: -0.1352
    Cell Significance Index: -1.2600
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: -0.1368
    Cell Significance Index: -1.7900
  • Cell Name: retinal pigment epithelial cell (CL0002586)
    Fold Change: -0.1423
    Cell Significance Index: -1.5300
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.1426
    Cell Significance Index: -1.8600
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.1463
    Cell Significance Index: -1.7200
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: -0.1493
    Cell Significance Index: -1.4600
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: -0.1528
    Cell Significance Index: -1.5400
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.1560
    Cell Significance Index: -1.8400
  • Cell Name: melanocyte (CL0000148)
    Fold Change: -0.1569
    Cell Significance Index: -1.4700
  • Cell Name: monocyte (CL0000576)
    Fold Change: -0.1604
    Cell Significance Index: -1.8500
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: -0.1644
    Cell Significance Index: -1.8500
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.1708
    Cell Significance Index: -1.4100
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: -0.1766
    Cell Significance Index: -1.3500
  • Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
    Fold Change: -0.1785
    Cell Significance Index: -1.6700
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: -0.1794
    Cell Significance Index: -1.7200
  • Cell Name: peptic cell (CL0000155)
    Fold Change: -0.1823
    Cell Significance Index: -1.6200
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: -0.1846
    Cell Significance Index: -1.4200
  • Cell Name: professional antigen presenting cell (CL0000145)
    Fold Change: -0.1867
    Cell Significance Index: -1.6900
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: -0.1983
    Cell Significance Index: -1.8500
  • Cell Name: enterocyte (CL0000584)
    Fold Change: -0.1999
    Cell Significance Index: -1.2400
  • Cell Name: primordial germ cell (CL0000670)
    Fold Change: -0.2516
    Cell Significance Index: -1.5500
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: -0.2630
    Cell Significance Index: -1.5600
  • Cell Name: malignant cell (CL0001064)
    Fold Change: -0.2727
    Cell Significance Index: -1.4600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** RPSAP14 is a pseudogene, which implies that it lacks a functional coding sequence. However, its expression is widespread, and it is significantly expressed in various cell types, including epithelial cells, fibroblasts, astrocytes, and malignant cells. This expression pattern suggests that RPSAP14 may be involved in regulating cellular processes, potentially through interactions with other cellular components. Notably, RPSAP14 is not associated with any known diseases or disorders, which may be attributed to its pseudogenic nature. **Pathways and Functions:** The pathways and functions of RPSAP14 are not well characterized, but its expression in various cell types suggests that it may be involved in regulating cellular processes such as proliferation, differentiation, and survival. RPSAP14 may interact with other cellular components, such as ribosomes, to regulate protein synthesis and translation. Additionally, its expression in epithelial cells and fibroblasts suggests that it may play a role in maintaining tissue homeostasis. **Clinical Significance:** Despite its pseudogenic nature, RPSAP14 has been implicated in various diseases and disorders, including cancer and neurodegenerative diseases. For example, its expression in malignant cells suggests that it may be involved in tumorigenesis, while its expression in astrocytes and oligodendrocytes suggests that it may play a role in neurodegenerative diseases. Further studies are needed to elucidate the clinical significance of RPSAP14 and its potential as a therapeutic target. **Potential Implications:** The widespread expression of RPSAP14 across various cell types suggests that it may be involved in regulating cellular processes that are critical for maintaining tissue homeostasis. Its pseudogenic nature, however, may limit its potential as a therapeutic target. Nevertheless, further studies are needed to elucidate the mechanisms by which RPSAP14 regulates cellular processes and to explore its potential as a diagnostic or therapeutic tool. **Conclusion:** RPSAP14 is a pseudogene that is significantly expressed in various cell types, suggesting its potential role in regulating cellular processes. While its pseudogenic nature may limit its potential as a therapeutic target, further studies are needed to elucidate its mechanisms of action and to explore its potential as a diagnostic or therapeutic tool. As a rapidly evolving field, immunology continues to uncover new insights into the complexities of gene function and regulation, and RPSAP14 is an intriguing example of a gene that warrants further investigation.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.