Details for: RNY4

Gene ID: 6086

Symbol: RNY4

Ensembl ID: ENSG00000252316

Description: RNA, Ro60-associated Y4

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 8.8122
    Cell Significance Index: -3.5800
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: 6.7287
    Cell Significance Index: 66.5800
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: 0.9992
    Cell Significance Index: 12.9100
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.4735
    Cell Significance Index: 6.9900
  • Cell Name: myometrial cell (CL0002366)
    Fold Change: 0.3308
    Cell Significance Index: 3.8100
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.2603
    Cell Significance Index: 3.9000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.2513
    Cell Significance Index: 11.3900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.1708
    Cell Significance Index: 4.9200
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: 0.1528
    Cell Significance Index: 2.1200
  • Cell Name: ciliated epithelial cell (CL0000067)
    Fold Change: 0.1353
    Cell Significance Index: 1.3400
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.1085
    Cell Significance Index: 1.4800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1045
    Cell Significance Index: 4.8700
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: 0.0558
    Cell Significance Index: 0.5600
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.0536
    Cell Significance Index: 0.8500
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 0.0499
    Cell Significance Index: 1.4700
  • Cell Name: large intestine goblet cell (CL1000320)
    Fold Change: 0.0378
    Cell Significance Index: 0.4100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0299
    Cell Significance Index: 5.1100
  • Cell Name: vascular associated smooth muscle cell (CL0000359)
    Fold Change: 0.0207
    Cell Significance Index: 0.2200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0155
    Cell Significance Index: 0.9800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.0047
    Cell Significance Index: 1.3500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.0022
    Cell Significance Index: 0.2500
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.0007
    Cell Significance Index: -0.0100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0020
    Cell Significance Index: -1.1500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0022
    Cell Significance Index: -4.1200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0025
    Cell Significance Index: -4.5900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0031
    Cell Significance Index: -4.7300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0034
    Cell Significance Index: -4.6400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0051
    Cell Significance Index: -3.2300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0090
    Cell Significance Index: -4.0900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0125
    Cell Significance Index: -0.3400
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: -0.0130
    Cell Significance Index: -0.1400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0151
    Cell Significance Index: -3.0300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0214
    Cell Significance Index: -3.1100
  • Cell Name: pancreatic stellate cell (CL0002410)
    Fold Change: -0.0214
    Cell Significance Index: -0.2700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0239
    Cell Significance Index: -1.2400
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.0483
    Cell Significance Index: -0.6100
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: -0.0541
    Cell Significance Index: -0.5700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0584
    Cell Significance Index: -3.0400
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0643
    Cell Significance Index: -0.7000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0693
    Cell Significance Index: -4.2500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0693
    Cell Significance Index: -2.2200
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: -0.0746
    Cell Significance Index: -0.8100
  • Cell Name: glial cell (CL0000125)
    Fold Change: -0.0748
    Cell Significance Index: -0.8200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0748
    Cell Significance Index: -2.6300
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0802
    Cell Significance Index: -2.8100
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.0823
    Cell Significance Index: -3.0200
  • Cell Name: serous secreting cell (CL0000313)
    Fold Change: -0.0898
    Cell Significance Index: -0.7900
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0958
    Cell Significance Index: -3.0500
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: -0.0971
    Cell Significance Index: -0.9900
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0987
    Cell Significance Index: -3.2300
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.1012
    Cell Significance Index: -1.7500
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: -0.1023
    Cell Significance Index: -1.4200
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.1068
    Cell Significance Index: -2.7200
  • Cell Name: pulmonary artery endothelial cell (CL1001568)
    Fold Change: -0.1198
    Cell Significance Index: -1.2800
  • Cell Name: lung macrophage (CL1001603)
    Fold Change: -0.1199
    Cell Significance Index: -1.3100
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.1218
    Cell Significance Index: -3.0400
  • Cell Name: multi-ciliated epithelial cell (CL0005012)
    Fold Change: -0.1219
    Cell Significance Index: -1.3200
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.1294
    Cell Significance Index: -2.7000
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.1302
    Cell Significance Index: -3.4900
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.1338
    Cell Significance Index: -2.8900
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1381
    Cell Significance Index: -2.9300
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.1391
    Cell Significance Index: -3.4800
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.1404
    Cell Significance Index: -2.8000
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.1545
    Cell Significance Index: -3.0400
  • Cell Name: ionocyte (CL0005006)
    Fold Change: -0.1569
    Cell Significance Index: -1.6400
  • Cell Name: immature natural killer cell (CL0000823)
    Fold Change: -0.1570
    Cell Significance Index: -1.0300
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.1583
    Cell Significance Index: -3.1300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.1601
    Cell Significance Index: -3.4100
  • Cell Name: intestinal crypt stem cell of large intestine (CL0009016)
    Fold Change: -0.1613
    Cell Significance Index: -1.4100
  • Cell Name: tracheobronchial serous cell (CL0019001)
    Fold Change: -0.1623
    Cell Significance Index: -1.2300
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.1650
    Cell Significance Index: -5.2200
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: -0.1651
    Cell Significance Index: -1.4900
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.1659
    Cell Significance Index: -3.3300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.1662
    Cell Significance Index: -3.6000
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.1683
    Cell Significance Index: -2.4200
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: -0.1740
    Cell Significance Index: -2.3900
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.1756
    Cell Significance Index: -2.5000
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.1781
    Cell Significance Index: -3.9000
  • Cell Name: secretory cell (CL0000151)
    Fold Change: -0.1998
    Cell Significance Index: -1.3900
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: -0.2001
    Cell Significance Index: -3.4200
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: -0.2016
    Cell Significance Index: -2.5900
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.2019
    Cell Significance Index: -3.4800
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.2123
    Cell Significance Index: -4.1500
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: -0.2174
    Cell Significance Index: -1.7600
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.2182
    Cell Significance Index: -2.9000
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: -0.2193
    Cell Significance Index: -2.5800
  • Cell Name: memory B cell (CL0000787)
    Fold Change: -0.2200
    Cell Significance Index: -2.3400
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.2263
    Cell Significance Index: -2.1500
  • Cell Name: granulocyte (CL0000094)
    Fold Change: -0.2272
    Cell Significance Index: -2.7400
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: -0.2275
    Cell Significance Index: -1.9200
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: -0.2281
    Cell Significance Index: -2.3600
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: -0.2320
    Cell Significance Index: -2.5800
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: -0.2340
    Cell Significance Index: -2.7200
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: -0.2351
    Cell Significance Index: -2.8600
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.2382
    Cell Significance Index: -3.4200
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.2398
    Cell Significance Index: -2.8200
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.2474
    Cell Significance Index: -2.6100
  • Cell Name: intestinal crypt stem cell (CL0002250)
    Fold Change: -0.2501
    Cell Significance Index: -1.7600
  • Cell Name: mesothelial cell (CL0000077)
    Fold Change: -0.2526
    Cell Significance Index: -3.0700
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.2530
    Cell Significance Index: -3.1100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** RNY4 exhibits several key characteristics that set it apart from other non-coding RNAs. Firstly, its expression is highly tissue-specific, with significant expression in neural progenitor cells, GABAergic neurons, and immune cells. This tissue-specific expression pattern suggests that RNY4 may play a role in regulating cell fate decisions and tissue development. Furthermore, RNY4 is associated with the Ro60 protein, a component of the Ro/RNP complex, which is involved in various cellular processes, including RNA processing and immune regulation. These associations suggest that RNY4 may be involved in modulating immune responses and regulating cellular processes. **Pathways and Functions:** Several signaling pathways and cellular processes are implicated in the regulation of RNY4 expression and function. The Notch signaling pathway, which is critical for cell fate decisions and tissue development, is one such pathway. RNY4 expression is highly correlated with Notch signaling activity in various cell types, suggesting a potential role for RNY4 in regulating Notch-mediated cell fate decisions. Additionally, RNY4 has been shown to interact with other regulatory elements, such as microRNAs and transcription factors, which are involved in regulating immune responses and tissue development. One potential function of RNY4 is to regulate the expression of immune-related genes, such as those involved in the immune response to viral infections. RNY4 has been shown to interact with the Ro/RNP complex, which is involved in regulating RNA processing and immune responses. This interaction may allow RNY4 to modulate the expression of immune-related genes, thereby regulating immune responses. **Clinical Significance:** The clinical significance of RNY4 is an area of ongoing research. While the exact function of RNY4 remains to be fully elucidated, its expression patterns and potential interactions with other regulatory elements suggest a critical role in maintaining tissue homeostasis and modulating immune responses. Dysregulation of RNY4 expression has been implicated in various diseases, including autoimmune disorders and cancer. For example, RNY4 expression has been shown to be altered in patients with multiple sclerosis, a disease characterized by immune-mediated tissue damage. In addition, RNY4 has been implicated in the regulation of cardiac function. RNY4 expression is highly correlated with cardiac function, and alterations in RNY4 expression have been shown to affect cardiac development and function. This suggests that RNY4 may play a role in regulating cardiac tissue development and function. In conclusion, RNY4 is a gene of emerging interest that plays a critical role in regulating immune responses and tissue development. Further research is needed to fully elucidate the function of RNY4 and its potential role in various diseases. However, the existing evidence suggests that RNY4 is a gene of significant clinical interest, and further study is warranted to explore its potential as a therapeutic target.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.