Details for: PSME4
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 2.76
Marker Score: 6,912 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 2.62
Marker Score: 9,305 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 2.56
Marker Score: 5,625 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 2.54
Marker Score: 56,697 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 2.28
Marker Score: 9,534 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 2.21
Marker Score: 697 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 2.17
Marker Score: 1,264 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 2.15
Marker Score: 2,379 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 2.14
Marker Score: 2,254 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 2.04
Marker Score: 43,491 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 1.99
Marker Score: 582 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 1.89
Marker Score: 996 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 1.87
Marker Score: 1,992 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: 1.85
Marker Score: 1,076 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 1.84
Marker Score: 2,228 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 1.83
Marker Score: 1,271 - Cell Name: lung goblet cell (CL1000143)
Fold Change: 1.83
Marker Score: 527 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.83
Marker Score: 67,330 - Cell Name: neuron (CL0000540)
Fold Change: 1.82
Marker Score: 7,412 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 1.82
Marker Score: 4,348 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 1.81
Marker Score: 1,607 - Cell Name: Sertoli cell (CL0000216)
Fold Change: 1.8
Marker Score: 10,654 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 1.78
Marker Score: 2,021 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 1.78
Marker Score: 2,396 - Cell Name: taste receptor cell (CL0000209)
Fold Change: 1.77
Marker Score: 1,527 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 1.75
Marker Score: 66,482 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 1.74
Marker Score: 2,005 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.74
Marker Score: 107,119 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 1.72
Marker Score: 2,889 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.7
Marker Score: 2,501 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 1.69
Marker Score: 535 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 1.67
Marker Score: 976 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 1.66
Marker Score: 822 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.65
Marker Score: 17,064 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.64
Marker Score: 14,062 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.64
Marker Score: 15,548 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 1.58
Marker Score: 6,547 - Cell Name: fat cell (CL0000136)
Fold Change: 1.58
Marker Score: 881 - Cell Name: endothelial cell of vascular tree (CL0002139)
Fold Change: 1.57
Marker Score: 2,275 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 1.55
Marker Score: 2,984 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 1.55
Marker Score: 23,190 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 1.55
Marker Score: 11,849 - Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 1.54
Marker Score: 764 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 1.54
Marker Score: 14,454 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 1.53
Marker Score: 30,484 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 1.53
Marker Score: 642 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.53
Marker Score: 2,362 - Cell Name: alveolar type 2 fibroblast cell (CL4028006)
Fold Change: 1.53
Marker Score: 850 - Cell Name: myoepithelial cell of mammary gland (CL0002324)
Fold Change: 1.47
Marker Score: 7,238 - Cell Name: mesangial cell (CL0000650)
Fold Change: 1.47
Marker Score: 1,778 - Cell Name: renal principal cell (CL0005009)
Fold Change: 1.47
Marker Score: 1,131 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 1.47
Marker Score: 499 - Cell Name: astrocyte (CL0000127)
Fold Change: 1.45
Marker Score: 1,260 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.45
Marker Score: 5,619 - Cell Name: epithelial cell of urethra (CL1000296)
Fold Change: 1.44
Marker Score: 1,138 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 1.41
Marker Score: 683 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 1.37
Marker Score: 1,479 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 1.37
Marker Score: 815 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 1.34
Marker Score: 8,644 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 1.34
Marker Score: 3,269 - Cell Name: lymphocyte (CL0000542)
Fold Change: 1.34
Marker Score: 675 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 1.33
Marker Score: 23,620 - Cell Name: lactocyte (CL0002325)
Fold Change: 1.27
Marker Score: 20,462 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 1.27
Marker Score: 43,315 - Cell Name: midzonal region hepatocyte (CL0019028)
Fold Change: 1.24
Marker Score: 5,369 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: 1.24
Marker Score: 467 - Cell Name: Unknown (CL0002371)
Fold Change: 1.21
Marker Score: 1,290 - Cell Name: basal cell (CL0000646)
Fold Change: 1.21
Marker Score: 1,564 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 1.2
Marker Score: 1,705 - Cell Name: innate lymphoid cell (CL0001065)
Fold Change: 1.19
Marker Score: 429 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 1.19
Marker Score: 445 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 1.19
Marker Score: 6,396 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 1.19
Marker Score: 2,705 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 1.18
Marker Score: 323 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: 1.18
Marker Score: 777 - Cell Name: alveolar macrophage (CL0000583)
Fold Change: 1.18
Marker Score: 30,115 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 1.16
Marker Score: 5,381 - Cell Name: podocyte (CL0000653)
Fold Change: 1.16
Marker Score: 429 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 1.16
Marker Score: 1,105 - Cell Name: nasal mucosa goblet cell (CL0002480)
Fold Change: 1.16
Marker Score: 774 - Cell Name: basal cell of epidermis (CL0002187)
Fold Change: 1.15
Marker Score: 504 - Cell Name: lens fiber cell (CL0011004)
Fold Change: 1.15
Marker Score: 364 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.15
Marker Score: 17,950 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: 1.15
Marker Score: 2,032 - Cell Name: papillary tips cell (CL1000597)
Fold Change: 1.14
Marker Score: 231 - Cell Name: club cell (CL0000158)
Fold Change: 1.13
Marker Score: 1,316 - Cell Name: ciliated cell (CL0000064)
Fold Change: 1.13
Marker Score: 3,870 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 1.12
Marker Score: 285 - Cell Name: duct epithelial cell (CL0000068)
Fold Change: 1.11
Marker Score: 520 - Cell Name: syncytiotrophoblast cell (CL0000525)
Fold Change: 1.1
Marker Score: 907 - Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
Fold Change: 1.09
Marker Score: 1,155 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 1.09
Marker Score: 4,194 - Cell Name: renal beta-intercalated cell (CL0002201)
Fold Change: 1.09
Marker Score: 344 - Cell Name: cardiac neuron (CL0010022)
Fold Change: 1.08
Marker Score: 1,341 - Cell Name: melanocyte (CL0000148)
Fold Change: 1.07
Marker Score: 432 - Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
Fold Change: 1.06
Marker Score: 1,139 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 1.05
Marker Score: 969 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 1.05
Marker Score: 1,299 - Cell Name: endocrine cell (CL0000163)
Fold Change: 1.05
Marker Score: 542 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 1.04
Marker Score: 585
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1847118801
Symbol: PSME4_HUMAN
Name: Proteasome activator complex subunit 4
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 7584044
Title: Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1.
PubMed ID: 7584044
PubMed ID: 12093752
Title: PA200, a nuclear proteasome activator involved in DNA repair.
PubMed ID: 12093752
DOI: 10.1093/emboj/cdf333
PubMed ID: 17323924
Title: Mass spectrometric characterization of the affinity-purified human 26S proteasome complex.
PubMed ID: 17323924
DOI: 10.1021/bi061994u
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 18845680
Title: Role for proteasome activator PA200 and postglutamyl proteasome activity in genomic stability.
PubMed ID: 18845680
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22550082
Title: The proteasome activator PA200 regulates tumor cell responsiveness to glutamine and resistance to ionizing radiation.
PubMed ID: 22550082
PubMed ID: 23706739
Title: Acetylation-mediated proteasomal degradation of core histones during DNA repair and spermatogenesis.
PubMed ID: 23706739
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
Sequence Information:
- Length: 1843
- Mass: 211334
- Checksum: 2D2C3A594E4FA4E7
- Sequence:
MEPAERAGVG EPPEPGGRPE PGPRGFVPQK EIVYNKLLPY AERLDAESDL QLAQIKCNLG RAVQLQELWP GGLFWTRKLS TYIRLYGRKF SKEDHVLFIK LLYELVSIPK LEISMMQGFA RLLINLLKKK ELLSRADLEL PWRPLYDMVE RILYSKTEHL GLNWFPNSVE NILKTLVKSC RPYFPADATA EMLEEWRPLM CPFDVTMQKA ITYFEIFLPT SLPPELHHKG FKLWFDELIG LWVSVQNLPQ WEGQLVNLFA RLATDNIGYI DWDPYVPKIF TRILRSLNLP VGSSQVLVPR FLTNAYDIGH AVIWITAMMG GPSKLVQKHL AGLFNSITSF YHPSNNGRWL NKLMKLLQRL PNSVVRRLHR ERYKKPSWLT PVPDSHKLTD QDVTDFVQCI IQPVLLAMFS KTGSLEAAQA LQNLALMRPE LVIPPVLERT YPALETLTEP HQLTATLSCV IGVARSLVSG GRWFPEGPTH MLPLLMRALP GVDPNDFSKC MITFQFIATF STLVPLVDCS SVLQERNDLT EVERELCSAT AEFEDFVLQF MDRCFGLIES STLEQTREET ETEKMTHLES LVELGLSSTF STILTQCSKE IFMVALQKVF NFSTSHIFET RVAGRMVADM CRAAVKCCPE ESLKLFVPHC CSVITQLTMN DDVLNDEELD KELLWNLQLL SEITRVDGRK LLLYREQLVK ILQRTLHLTC KQGYTLSCNL LHHLLRSTTL IYPTEYCSVP GGFDKPPSEY FPIKDWGKPG DLWNLGIQWH VPSSEEVSFA FYLLDSFLQP ELVKLQHCGD GKLEMSRDDI LQSLTIVHNC LIGSGNLLPP LKGEPVTNLV PSMVSLEETK LYTGLEYDLS RENHREVIAT VIRKLLNHIL DNSEDDTKSL FLIIKIIGDL LQFQGSHKHE FDSRWKSFNL VKKSMENRLH GKKQHIRALL IDRVMLQHEL RTLTVEGCEY KKIHQDMIRD LLRLSTSSYS QVRNKAQQTF FAALGAYNFC CRDIIPLVLE FLRPDRQGVT QQQFKGALYC LLGNHSGVCL ANLHDWDCIV QTWPAIVSSG LSQAMSLEKP SIVRLFDDLA EKIHRQYETI GLDFTIPKSC VEIAELLQQS KNPSINQILL SPEKIKEGIK RQQEKNADAL RNYENLVDTL LDGVEQRNLP WKFEHIGIGL LSLLLRDDRV LPLRAIRFFV ENLNHDAIVV RKMAISAVAG ILKQLKRTHK KLTINPCEIS GCPKPTQIIA GDRPDNHWLH YDSKTIPRTK KEWESSCFVE KTHWGYYTWP KNMVVYAGVE EQPKLGRSRE DMTEAEQIIF DHFSDPKFVE QLITFLSLED RKGKDKFNPR RFCLFKGIFR NFDDAFLPVL KPHLEHLVAD SHESTQRCVA EIIAGLIRGS KHWTFEKVEK LWELLCPLLR TALSNITVET YNDWGACIAT SCESRDPRKL HWLFELLLES PLSGEGGSFV DACRLYVLQG GLAQQEWRVP ELLHRLLKYL EPKLTQVYKN VRERIGSVLT YIFMIDVSLP NTTPTISPHV PEFTARILEK LKPLMDVDEE IQNHVMEENG IGEEDERTQG IKLLKTILKW LMASAGRSFS TAVTEQLQLL PLFFKIAPVE NDNSYDELKR DAKLCLSLMS QGLLYPHQVP LVLQVLKQTA RSSSWHARYT VLTYLQTMVF YNLFIFLNNE DAVKDIRWLV ISLLEDEQLE VREMAATTLS GLLQCNFLTM DSPMQIHFEQ LCKTKLPKKR KRDPGSVGDT IPSAELVKRH AGVLGLGACV LSSPYDVPTW MPQLLMNLSA HLNDPQPIEM TVKKTLSNFR RTHHDNWQEH KQQFTDDQLL VLTDLLVSPC YYA
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.