Details for: CCDC171
Gene ID: 203238
Gene Type: Protein-coding - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.
Symbol: CCDC171
Ensembl ID: ENSG00000164989
Description: coiled-coil domain containing 171
Selected Context(s): Overall
Cell Significance Landscape
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 16.02rCSI 38.93%PRS 72.01
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CSI 15.96rCSI 26.78%PRS 74.3
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CSI 12.46rCSI 44.85%PRS 72.25
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CSI 10.47rCSI 16.54%PRS 89.46
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CSI 10.32rCSI 21.41%PRS 86.61
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CSI 10.07rCSI 22.25%PRS 77.05
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CSI 9.47rCSI 8.33%PRS 79.53
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CSI 9.46rCSI 29.56%PRS 75.72
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CSI 9.4rCSI 35.51%PRS 74.6
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CSI 8.89rCSI 11.42%PRS 79.81
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CSI 8.07rCSI 11.22%PRS 86.95
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CSI 7.37rCSI 43.39%PRS 74.75
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CSI 6.95rCSI 12.25%PRS 84.38
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CSI 6.85rCSI 23.46%PRS 75.6
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CSI 6.28rCSI 4.65%PRS 84.28
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CSI 6.2rCSI 24.24%PRS 70.46
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CSI 5.99rCSI 44.01%PRS 79.08
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CSI 5.67rCSI 9.05%PRS 80.81
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CSI 5.63rCSI 6.5%PRS 81.29
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CSI 5.51rCSI 8.87%PRS 75.47
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CSI 5.32rCSI 11.66%PRS 91.36
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CSI 5.32rCSI 10.79%PRS 70.1
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CSI 5.26rCSI 4.16%PRS 80.63
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CSI 5.23rCSI 13.92%PRS 76.36
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CSI 4.85rCSI 18.28%PRS 73.04
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CSI 4.83rCSI 8.36%PRS 82.54
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CSI 4.82rCSI 11%PRS 81.46
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CSI 4.81rCSI 9.66%PRS 81.76
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CSI 4.66rCSI 6.01%PRS 75.45
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CSI 4.59rCSI 28.67%PRS 81.82
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CSI 4.51rCSI 7%PRS 90.04
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CSI 4.4rCSI 10.15%PRS 78.83
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CSI 4.38rCSI 8.2%PRS 79.3
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CSI 4.15rCSI 19.88%PRS 84.61
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CSI 4.13rCSI 10.77%PRS 89.87
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CSI 4.08rCSI 4.19%PRS 95.07
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CSI 4.04rCSI 15.38%PRS 81.45
-
CSI 4.03rCSI 6.4%PRS 83.44
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CSI 3.98rCSI 4.76%PRS 74.43
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CSI 3.96rCSI 7%PRS 73.8
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CSI 3.94rCSI 3.56%PRS 87.44
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CSI 3.9rCSI 12.47%PRS 86.74
-
CSI 3.72rCSI 8.89%PRS 77.38
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CSI 3.71rCSI 6.51%PRS 84.43
-
CSI 3.71rCSI 10.01%PRS 91
-
CSI 3.64rCSI 31.44%PRS 82.88
-
CSI 3.64rCSI 5.95%PRS 80.66
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CSI 3.63rCSI 4.94%PRS 81.85
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CSI 3.57rCSI 4.44%PRS 72.08
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CSI 3.5rCSI 5.15%PRS 82.83
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CSI 3.43rCSI 6.16%PRS 83.11
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CSI 3.12rCSI 12.6%PRS 89.16
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CSI 3.11rCSI 2.07%PRS 90.37
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CSI 3.1rCSI 11.62%PRS 83.28
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CSI 3.05rCSI 17.57%PRS 85.34
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CSI 3rCSI 10.04%PRS 74.48
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CSI 2.93rCSI 7.15%PRS 81.51
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CSI 2.91rCSI 4.72%PRS 82.97
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CSI 2.87rCSI 6.44%PRS 74.93
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CSI 2.87rCSI 3.14%PRS 90.01
-
CSI 2.8rCSI 3.83%PRS 80.54
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CSI 2.79rCSI 7.07%PRS 81.54
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CSI 2.74rCSI 2.22%PRS 90.28
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CSI 2.72rCSI 5.58%PRS 76.58
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CSI 2.71rCSI 7.05%PRS 82.54
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CSI 2.66rCSI 3.77%PRS 85.94
-
CSI 2.65rCSI 6.33%PRS 88.55
-
CSI 2.65rCSI 8.7%PRS 76.31
-
CSI 2.54rCSI 2.53%PRS 82.91
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CSI 2.53rCSI 6.27%PRS 88.89
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CSI 2.53rCSI 6.53%PRS 85.17
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CSI 2.52rCSI 1.95%PRS 91.37
-
CSI 2.4rCSI 11.51%PRS 89.14
-
CSI 2.34rCSI 5.92%PRS 91.42
-
CSI 2.29rCSI 46.72%PRS 79.39
-
CSI 2.29rCSI 3.29%PRS 80.18
-
CSI 2.22rCSI 5.93%PRS 82.45
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CSI 2.21rCSI 4.4%PRS 84.78
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CSI 2.2rCSI 52.56%PRS 71.95
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CSI 2.19rCSI 6.86%PRS 77.62
-
CSI 2.13rCSI 43.31%PRS 80.22
-
CSI 2.09rCSI 10.37%PRS 82.92
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CSI 2.05rCSI 6.93%PRS 83.93
-
CSI 2.04rCSI 3.12%PRS 87.9
-
CSI 1.96rCSI 3.16%PRS 80.34
-
CSI 1.93rCSI 4.41%PRS 81.79
-
CSI 1.92rCSI 4.98%PRS 88.01
-
CSI 1.88rCSI 3.42%PRS 81.77
-
CSI 1.86rCSI 8.2%PRS 77.64
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CSI 1.83rCSI 3.98%PRS 77.14
-
CSI 1.8rCSI 5.07%PRS 84.33
-
CSI 1.73rCSI 5.01%PRS 79.59
-
CSI 1.66rCSI 1.92%PRS 82.71
-
CSI 1.6rCSI 4.11%PRS 84.55
-
CSI 1.59rCSI 7.07%PRS 89.11
-
CSI 1.58rCSI 22.48%PRS 80.61
-
CSI 1.5rCSI 4.12%PRS 85.35
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CSI 1.49rCSI 4.31%PRS 87.65
-
CSI 1.45rCSI 1.8%PRS 87.12
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CSI 1.33rCSI 5.85%PRS 83.46
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CSI 0.3rCSI 2.6%PRS 79.7%
-
CSI 0.5rCSI 4.9%PRS 84.5%
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CSI 0.7rCSI 5.4%PRS 75.6%
-
CSI 0.7rCSI 4.6%PRS 78.8%
-
CSI 0.7rCSI 3.5%PRS 96.8%
-
CSI 0.8rCSI 4.6%PRS 79.9%
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CSI 0.8rCSI 5.3%PRS 82.4%
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CSI 0.8rCSI 6.5%PRS 84.9%
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CSI 1.0rCSI 6.4%PRS 80.6%
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CSI 1.0rCSI 4.0%PRS 82.6%
-
CSI 1.0rCSI 2.5%PRS 96.1%
-
CSI 1.1rCSI 2.6%PRS 89.9%
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CSI 1.1rCSI 2.0%PRS 59.1%
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CSI 1.1rCSI 4.6%PRS 93.8%
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CSI 1.2rCSI 3.8%PRS 85.2%
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CSI 1.2rCSI 5.8%PRS 79.2%
-
CSI 1.3rCSI 5.9%PRS 83.5%
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CSI 1.5rCSI 1.8%PRS 87.1%
-
CSI 1.5rCSI 4.3%PRS 87.7%
-
CSI 1.5rCSI 4.1%PRS 85.4%
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CSI 1.6rCSI 22.5%PRS 80.6%
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CSI 1.6rCSI 7.1%PRS 89.1%
-
CSI 1.6rCSI 4.1%PRS 84.6%
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CSI 1.7rCSI 1.9%PRS 82.7%
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CSI 1.7rCSI 5.0%PRS 79.6%
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CSI 1.8rCSI 5.1%PRS 84.3%
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CSI 1.8rCSI 4.0%PRS 77.1%
-
CSI 1.9rCSI 8.2%PRS 77.6%
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CSI 1.9rCSI 3.4%PRS 81.8%
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CSI 1.9rCSI 5.0%PRS 88.0%
-
CSI 1.9rCSI 4.4%PRS 81.8%
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CSI 2.0rCSI 3.2%PRS 80.3%
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CSI 2.0rCSI 3.1%PRS 87.9%
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CSI 2.1rCSI 6.9%PRS 83.9%
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CSI 2.1rCSI 10.4%PRS 82.9%
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CSI 2.1rCSI 43.3%PRS 80.2%
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CSI 2.2rCSI 6.9%PRS 77.6%
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CSI 2.2rCSI 52.6%PRS 72.0%
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CSI 2.2rCSI 4.4%PRS 84.8%
-
CSI 2.2rCSI 5.9%PRS 82.5%
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CSI 2.3rCSI 3.3%PRS 80.2%
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CSI 2.3rCSI 46.7%PRS 79.4%
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CSI 2.3rCSI 5.9%PRS 91.4%
-
CSI 2.4rCSI 11.5%PRS 89.1%
-
CSI 2.5rCSI 2.0%PRS 91.4%
-
CSI 2.5rCSI 6.5%PRS 85.2%
-
CSI 2.5rCSI 6.3%PRS 88.9%
-
CSI 2.5rCSI 2.5%PRS 82.9%
-
CSI 2.7rCSI 8.7%PRS 76.3%
-
CSI 2.7rCSI 6.3%PRS 88.6%
-
CSI 2.7rCSI 3.8%PRS 85.9%
-
CSI 2.7rCSI 7.1%PRS 82.5%
-
CSI 2.7rCSI 5.6%PRS 76.6%
-
CSI 2.7rCSI 2.2%PRS 90.3%
-
CSI 2.8rCSI 7.1%PRS 81.5%
-
CSI 2.8rCSI 3.8%PRS 80.5%
-
CSI 2.9rCSI 3.1%PRS 90.0%
-
CSI 2.9rCSI 6.4%PRS 74.9%
-
CSI 2.9rCSI 4.7%PRS 83.0%
-
CSI 2.9rCSI 7.2%PRS 81.5%
-
CSI 3.0rCSI 10.0%PRS 74.5%
-
CSI 3.1rCSI 17.6%PRS 85.3%
-
CSI 3.1rCSI 11.6%PRS 83.3%
-
CSI 3.1rCSI 2.1%PRS 90.4%
-
CSI 3.1rCSI 12.6%PRS 89.2%
-
CSI 3.4rCSI 6.2%PRS 83.1%
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CSI 3.5rCSI 5.2%PRS 82.8%
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CSI 3.6rCSI 4.4%PRS 72.1%
-
CSI 3.6rCSI 4.9%PRS 81.9%
-
CSI 3.6rCSI 6.0%PRS 80.7%
-
CSI 3.6rCSI 31.4%PRS 82.9%
-
CSI 3.7rCSI 10.0%PRS 91.0%
-
CSI 3.7rCSI 6.5%PRS 84.4%
-
CSI 3.7rCSI 8.9%PRS 77.4%
-
CSI 3.9rCSI 12.5%PRS 86.7%
-
CSI 3.9rCSI 3.6%PRS 87.4%
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CSI 4.0rCSI 7.0%PRS 73.8%
-
CSI 4.0rCSI 4.8%PRS 74.4%
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CSI 4.0rCSI 6.4%PRS 83.4%
-
CSI 4.0rCSI 15.4%PRS 81.5%
-
CSI 4.1rCSI 4.2%PRS 95.1%
-
CSI 4.1rCSI 10.8%PRS 89.9%
-
CSI 4.2rCSI 19.9%PRS 84.6%
-
CSI 4.4rCSI 8.2%PRS 79.3%
-
CSI 4.4rCSI 10.2%PRS 78.8%
-
CSI 4.5rCSI 7.0%PRS 90.0%
-
CSI 4.6rCSI 28.7%PRS 81.8%
-
CSI 4.7rCSI 6.0%PRS 75.5%
-
CSI 4.8rCSI 9.7%PRS 81.8%
-
CSI 4.8rCSI 11.0%PRS 81.5%
-
CSI 4.8rCSI 8.4%PRS 82.5%
-
CSI 4.9rCSI 18.3%PRS 73.0%
-
CSI 5.2rCSI 13.9%PRS 76.4%
-
CSI 5.3rCSI 4.2%PRS 80.6%
-
CSI 5.3rCSI 10.8%PRS 70.1%
-
CSI 5.3rCSI 11.7%PRS 91.4%
-
CSI 5.5rCSI 8.9%PRS 75.5%
-
CSI 5.6rCSI 6.5%PRS 81.3%
-
CSI 5.7rCSI 9.1%PRS 80.8%
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CSI 6.0rCSI 44.0%PRS 79.1%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Legend:
- Query Gene
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Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 542653211
Symbol: CC171_HUMAN
Name: Coiled-coil domain-containing protein 171
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15164053
Title: DNA sequence and analysis of human chromosome 9.
PubMed ID: 15164053
DOI: 10.1038/nature02465
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 1326
- Mass: 152810
- Checksum: 27116BFFDBBD46F8
- Sequence:
MNLNTSSNTG DTQRLKIASL DVKQILKNET ELDITDNLRK KLHWAKKEKL EITTKHNAEL ASYESQIAKL RSEVEKGEAL RQSLEYDLAV ARKEAGLGRR AAEERLAEAH RIQEKLCAQN SELQAKTNET EKAFQTSQQK WKEECRRFEH DLEERDNMIQ NCNREYDLLM KEKSRLEKTL QEALEKHQRE KNEMESHIRE TALEEFRLQE EQWEAERREL QFIVQEQDTA VQNMHKKVEK LETEHMDCSD LLRRQTSELE FSTQREERLR KEFEATTLRV RKLEENIEAE RAAHLESKFN SEIIQLRIRD LEGALQVEKA SQAEAVADLE IIKNEFKEVE SAYEREKHNA QESFAKLNLL EKEYFSKNKK LNEDIEEQKK VIIDLSKRLQ YNEKSCSELQ EELVMAKKHQ AFLVETCENN VKELESILDS FTVSGQWTSG IHKDKDKPPS FSVVLERLRR TLTDYQNKLE DASNEEKACN ELDSTKQKID SHTKNIKELQ DKLADVNKEL SHLHTKCADR EALISTLKVE LQNVLHCWEK EKAQAAQSES ELQKLSQAFH KDAEEKLTFL HTLYQHLVAG CVLIKQPEGM LDKFSWSELC AVLQENVDAL IADLNRANEK IRHLEYICKN KSDTMRELQQ TQEDTFTKVA EQIKAQESCW HRQKKELELQ YSELFLEVQK RAQKFQEIAE KNMEKLNHIE KSHEQLVLEN SHFKKLLSQT QREQMSLLAA CALMAGALYP LYSRSCALST QRDFLQEQVN TFELFKLEIR TLAQALSTVE EKKQEEAKMK KKTFKGLIRI FRKGVIAVLA ANRLKILGQS CASLFTWMES FKEGIGMLVC TGEPQDKHKF PKHQKEQLRC LQALSWLTSS DLLAAIISSM AELQDVIGKA DPNSRICGHL LIGAAKNSFA KLMDKISLVM ECIPLHSSRS ITYVEKDSLV QRLAHGLHKV NTLALKYGLR GHVPITKSTA SLQKQILGFT QRLHAAEVER RSLRLEVTEF KRSVNEMKKE LDKAQGLQMQ LNEFKQSKLI THEKFESACE ELNNALLREE QAQMLLNEQA QQLQELNYKL ELHSSEEADK NQTLGEAVKS LSEAKMELRR KDQSLRQLNR HLTQLEQDKR RLEENIHDAE SALRMAAKDK ECVANHMRAV ENTLHKVRDQ ISLSWSAASR NDFTLQLPKL HLETFAMEGL KGGPEVVACQ AMIKSFMDVY QLASTRIMTL EKEMTSHRSH IAALKSELHT ACLRENASLQ SIGSRDHSNL SIPSRAPLPA DTTGIGDFLP LKAELDTTYT FLKETFINTV PHALTSSHSS PVTMSANANR PTQIGL