Details for: MTX1LP

Gene ID: 4581

Symbol: MTX1LP

Ensembl ID: ENSG00000236675

Description: metaxin 1 like, pseudogene

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: 1.3393
    Cell Significance Index: 11.8000
  • Cell Name: stromal cell (CL0000499)
    Fold Change: 0.1096
    Cell Significance Index: 1.1200
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: 0.0739
    Cell Significance Index: 0.7800
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.0562
    Cell Significance Index: 0.8300
  • Cell Name: elicited macrophage (CL0000861)
    Fold Change: 0.0469
    Cell Significance Index: 0.4100
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 0.0388
    Cell Significance Index: 0.9700
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0003
    Cell Significance Index: -0.5300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0005
    Cell Significance Index: -0.9000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0007
    Cell Significance Index: -1.0300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0010
    Cell Significance Index: -1.3200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0018
    Cell Significance Index: -1.1700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0027
    Cell Significance Index: -1.2400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0029
    Cell Significance Index: -0.4900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0065
    Cell Significance Index: -0.9400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0085
    Cell Significance Index: -0.9700
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.0183
    Cell Significance Index: -0.5400
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: -0.0229
    Cell Significance Index: -0.2100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0287
    Cell Significance Index: -1.3400
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.0318
    Cell Significance Index: -0.5500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0448
    Cell Significance Index: -1.2200
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.0487
    Cell Significance Index: -1.5400
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.0596
    Cell Significance Index: -0.7800
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: -0.0620
    Cell Significance Index: -0.7300
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.0654
    Cell Significance Index: -1.1100
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.0707
    Cell Significance Index: -0.6700
  • Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
    Fold Change: -0.0806
    Cell Significance Index: -0.8400
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0865
    Cell Significance Index: -1.1800
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: -0.0902
    Cell Significance Index: -0.8400
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: -0.0953
    Cell Significance Index: -1.0600
  • Cell Name: monocyte (CL0000576)
    Fold Change: -0.0956
    Cell Significance Index: -1.1000
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: -0.0972
    Cell Significance Index: -0.9400
  • Cell Name: non-classical monocyte (CL0000875)
    Fold Change: -0.1039
    Cell Significance Index: -1.1500
  • Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
    Fold Change: -0.1044
    Cell Significance Index: -0.9900
  • Cell Name: neutrophil (CL0000775)
    Fold Change: -0.1049
    Cell Significance Index: -1.3100
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: -0.1108
    Cell Significance Index: -1.0000
  • Cell Name: mast cell (CL0000097)
    Fold Change: -0.1109
    Cell Significance Index: -1.4600
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: -0.1117
    Cell Significance Index: -1.5200
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: -0.1134
    Cell Significance Index: -1.3500
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: -0.1135
    Cell Significance Index: -1.4900
  • Cell Name: B cell (CL0000236)
    Fold Change: -0.1138
    Cell Significance Index: -1.3500
  • Cell Name: alveolar adventitial fibroblast (CL4028006)
    Fold Change: -0.1143
    Cell Significance Index: -1.2700
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: -0.1145
    Cell Significance Index: -1.3800
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: -0.1151
    Cell Significance Index: -1.4000
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: -0.1158
    Cell Significance Index: -1.4000
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.1165
    Cell Significance Index: -1.5200
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: -0.1172
    Cell Significance Index: -1.5300
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: -0.1177
    Cell Significance Index: -1.3300
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: -0.1180
    Cell Significance Index: -1.3900
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: -0.1186
    Cell Significance Index: -1.4800
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: -0.1186
    Cell Significance Index: -1.4100
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.1194
    Cell Significance Index: -1.7000
  • Cell Name: amacrine cell (CL0000561)
    Fold Change: -0.1198
    Cell Significance Index: -1.5000
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.1202
    Cell Significance Index: -1.4300
  • Cell Name: retina horizontal cell (CL0000745)
    Fold Change: -0.1203
    Cell Significance Index: -1.5100
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.1216
    Cell Significance Index: -1.4500
  • Cell Name: plasma cell (CL0000786)
    Fold Change: -0.1217
    Cell Significance Index: -1.3600
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: -0.1218
    Cell Significance Index: -1.2600
  • Cell Name: mesothelial cell (CL0000077)
    Fold Change: -0.1226
    Cell Significance Index: -1.4900
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -0.1237
    Cell Significance Index: -1.5000
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: -0.1241
    Cell Significance Index: -1.3800
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: -0.1255
    Cell Significance Index: -1.9100
  • Cell Name: vein endothelial cell (CL0002543)
    Fold Change: -0.1277
    Cell Significance Index: -1.3900
  • Cell Name: conventional dendritic cell (CL0000990)
    Fold Change: -0.1278
    Cell Significance Index: -1.5100
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.1284
    Cell Significance Index: -1.4700
  • Cell Name: pulmonary alveolar type 1 cell (CL0002062)
    Fold Change: -0.1294
    Cell Significance Index: -1.4200
  • Cell Name: fibroblast (CL0000057)
    Fold Change: -0.1299
    Cell Significance Index: -1.2200
  • Cell Name: capillary endothelial cell (CL0002144)
    Fold Change: -0.1303
    Cell Significance Index: -1.4800
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.1324
    Cell Significance Index: -1.4200
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: -0.1326
    Cell Significance Index: -1.5200
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: -0.1326
    Cell Significance Index: -1.5400
  • Cell Name: myofibroblast cell (CL0000186)
    Fold Change: -0.1336
    Cell Significance Index: -1.4000
  • Cell Name: lung macrophage (CL1001603)
    Fold Change: -0.1355
    Cell Significance Index: -1.4800
  • Cell Name: club cell (CL0000158)
    Fold Change: -0.1358
    Cell Significance Index: -1.4800
  • Cell Name: alveolar type 1 fibroblast cell (CL4028004)
    Fold Change: -0.1361
    Cell Significance Index: -1.4400
  • Cell Name: macrophage (CL0000235)
    Fold Change: -0.1371
    Cell Significance Index: -1.4000
  • Cell Name: bronchus fibroblast of lung (CL2000093)
    Fold Change: -0.1382
    Cell Significance Index: -1.4800
  • Cell Name: platelet (CL0000233)
    Fold Change: -0.1400
    Cell Significance Index: -1.4400
  • Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
    Fold Change: -0.1411
    Cell Significance Index: -1.3200
  • Cell Name: multi-ciliated epithelial cell (CL0005012)
    Fold Change: -0.1423
    Cell Significance Index: -1.5400
  • Cell Name: retinal pigment epithelial cell (CL0002586)
    Fold Change: -0.1432
    Cell Significance Index: -1.5400
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: -0.1433
    Cell Significance Index: -1.3300
  • Cell Name: pulmonary artery endothelial cell (CL1001568)
    Fold Change: -0.1441
    Cell Significance Index: -1.5400
  • Cell Name: tracheobronchial smooth muscle cell (CL0019019)
    Fold Change: -0.1467
    Cell Significance Index: -1.5100
  • Cell Name: respiratory basal cell (CL0002633)
    Fold Change: -0.1490
    Cell Significance Index: -1.4700
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: -0.1490
    Cell Significance Index: -1.5200
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: -0.1498
    Cell Significance Index: -1.4600
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: -0.1507
    Cell Significance Index: -2.0700
  • Cell Name: lung pericyte (CL0009089)
    Fold Change: -0.1541
    Cell Significance Index: -1.5200
  • Cell Name: lung neuroendocrine cell (CL1000223)
    Fold Change: -0.1553
    Cell Significance Index: -1.5400
  • Cell Name: melanocyte (CL0000148)
    Fold Change: -0.1569
    Cell Significance Index: -1.4700
  • Cell Name: enterocyte (CL0000584)
    Fold Change: -0.1580
    Cell Significance Index: -0.9800
  • Cell Name: pulmonary alveolar type 2 cell (CL0002063)
    Fold Change: -0.1596
    Cell Significance Index: -1.3200
  • Cell Name: respiratory hillock cell (CL4030023)
    Fold Change: -0.1601
    Cell Significance Index: -1.5200
  • Cell Name: OFF-bipolar cell (CL0000750)
    Fold Change: -0.1657
    Cell Significance Index: -1.4600
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: -0.1742
    Cell Significance Index: -1.9500
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.1793
    Cell Significance Index: -1.4800
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.1806
    Cell Significance Index: -2.2200
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: -0.1963
    Cell Significance Index: -1.5100
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: -0.2042
    Cell Significance Index: -1.9600
  • Cell Name: neuroblast (sensu Nematoda and Protostomia) (CL0000338)
    Fold Change: -0.2376
    Cell Significance Index: -2.1600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** MTX1LP is a pseudogene, meaning that it lacks a functional coding sequence and does not produce a protein. However, its expression in numerous cell types suggests that it may be involved in regulating gene expression or modulating cellular processes. The cell types that express MTX1LP highlight its potential role in tissue development, immune responses, and cellular regulation. The pseudogene's ability to be expressed in various cell types suggests that it may be subject to multiple regulatory mechanisms, influencing the expression of other genes or proteins. **Pathways and Functions:** While the exact function of MTX1LP remains unclear, its expression in cells involved in immune responses, such as innate lymphoid cells and central nervous system macrophages, suggests that it may be involved in modulating immune responses or regulating inflammation. The presence of MTX1LP in epithelial cells and melanocytes implies that it may play a role in tissue development and cellular differentiation. Additionally, its expression in astrocytes and ependymal cells may indicate a role in maintaining the central nervous system's microenvironment. The MTX1LP gene's expression in plasma cells suggests that it may be involved in the regulation of immune responses, particularly in the context of B-cell development and function. Furthermore, the presence of MTX1LP in ciliary epithelial cells implies that it may play a role in the regulation of ion and water transport in the eye. The pseudogene's expression in adventitial cells may be related to the regulation of vascular tone and blood pressure. **Clinical Significance:** The identification of MTX1LP as a pseudogene with widespread expression in various cell types has significant implications for our understanding of immune responses, tissue development, and cellular regulation. Further research is needed to elucidate the functional significance of MTX1LP and its role in disease processes. In the context of neurological disorders, such as multiple sclerosis, the expression of MTX1LP in central nervous system macrophages and astrocytes may be related to the regulation of immune responses and inflammation. Additionally, the pseudogene's expression in melanocytes may be relevant to the pathogenesis of melanoma. In the context of immune disorders, such as rheumatoid arthritis, the expression of MTX1LP in epithelial cells and innate lymphoid cells may be related to the regulation of immune responses and inflammation. Furthermore, the pseudogene's expression in plasma cells may be relevant to the regulation of B-cell development and function. In conclusion, the MTX1LP gene, a pseudogene with widespread expression in various cell types, warrants further investigation into its functional significance and clinical relevance. Further research is needed to elucidate the role of MTX1LP in disease processes and to explore its potential as a therapeutic target.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.