Details for: DZIP3
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 35.3rCSI 40.82%PRS 72.74
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CSI 30.93rCSI 49.78%PRS 70.55
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CSI 22.66rCSI 45.99%PRS 58.97
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CSI 22.54rCSI 54.78%PRS 60.51
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CSI 21.72rCSI 19.1%PRS 69.67
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CSI 19.5rCSI 31.59%PRS 75.24
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CSI 18.13rCSI 30.42%PRS 62.48
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CSI 16.09rCSI 50.29%PRS 64.19
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CSI 15.58rCSI 35.53%PRS 74.09
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CSI 13.52rCSI 48.66%PRS 60.42
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CSI 13.37rCSI 16.63%PRS 60.43
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CSI 11.27rCSI 24.91%PRS 66.18
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CSI 10.62rCSI 40.12%PRS 62.98
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CSI 10.14rCSI 44.56%PRS 75.4
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CSI 10.06rCSI 11.78%PRS 92.51
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CSI 9.51rCSI 22.57%PRS 80.54
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CSI 9.51rCSI 32.57%PRS 66.64
-
CSI 9.4rCSI 7.6%PRS 88.57
-
CSI 8.64rCSI 27.02%PRS 66.49
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CSI 8.16rCSI 48.07%PRS 63.23
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CSI 8.05rCSI 22.89%PRS 76.1
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CSI 7.82rCSI 57.48%PRS 67.86
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CSI 7.74rCSI 43.76%PRS 66.52
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CSI 7.73rCSI 24.73%PRS 77.69
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CSI 7.72rCSI 9.95%PRS 63.63
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CSI 7.59rCSI 11.22%PRS 84.22
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CSI 7.43rCSI 19.78%PRS 68.05
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CSI 6.62rCSI 4.92%PRS 90.24
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CSI 6.41rCSI 6.87%PRS 81.71
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CSI 6.11rCSI 9.82%PRS 64.06
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CSI 6.04rCSI 12.13%PRS 70.64
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CSI 5.99rCSI 7.15%PRS 62.6
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CSI 5.93rCSI 8.41%PRS 77.04
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CSI 5.92rCSI 10.38%PRS 74.32
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CSI 5.76rCSI 8%PRS 78.86
-
CSI 5.65rCSI 4.18%PRS 73.99
-
CSI 5.56rCSI 6.77%PRS 86.63
-
CSI 5.55rCSI 3.74%PRS 91.94
-
CSI 5.46rCSI 20.78%PRS 71.32
-
CSI 5.35rCSI 5.34%PRS 74.19
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CSI 4.93rCSI 11.25%PRS 71.88
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CSI 4.9rCSI 8.66%PRS 61.84
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CSI 4.85rCSI 7.73%PRS 71.94
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CSI 4.76rCSI 22.81%PRS 80.19
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CSI 4.6rCSI 5.9%PRS 70.53
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CSI 4.59rCSI 3.57%PRS 92.82
-
CSI 4.55rCSI 5.8%PRS 85.2
-
CSI 4.53rCSI 6.19%PRS 80.11
-
CSI 4.46rCSI 17.76%PRS 87.33
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CSI 4.31rCSI 4.52%PRS 83.57
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CSI 4.24rCSI 6.74%PRS 73.47
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CSI 4.19rCSI 10.23%PRS 72.73
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CSI 4.13rCSI 5.3%PRS 76.46
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CSI 4.13rCSI 6.76%PRS 69.94
-
CSI 4.11rCSI 6.1%PRS 80.34
-
CSI 4.11rCSI 7.69%PRS 68.84
-
CSI 4.1rCSI 7.09%PRS 72.03
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CSI 4rCSI 8.68%PRS 68.08
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CSI 3.9rCSI 7.01%PRS 73.79
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CSI 3.87rCSI 4.24%PRS 82.18
-
CSI 3.76rCSI 8.67%PRS 68.36
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CSI 3.68rCSI 2.91%PRS 69.26
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CSI 3.65rCSI 3.39%PRS 81.11
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CSI 3.63rCSI 22.67%PRS 72.09
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CSI 3.59rCSI 4.89%PRS 72.05
-
CSI 3.5rCSI 10.32%PRS 81.21
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CSI 3.47rCSI 3.05%PRS 85.02
-
CSI 3.46rCSI 8.27%PRS 67.31
-
CSI 3.29rCSI 4.83%PRS 73.34
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CSI 3.24rCSI 10.84%PRS 64.23
-
CSI 3.23rCSI 13.16%PRS 72.42
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CSI 3.19rCSI 45.34%PRS 71.42
-
CSI 3.15rCSI 3.63%PRS 72.49
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CSI 3.14rCSI 5.54%PRS 75.91
-
CSI 3.1rCSI 2.98%PRS 73.7
-
CSI 3.02rCSI 4.03%PRS 86.4
-
CSI 2.91rCSI 8.02%PRS 75.5
-
CSI 2.81rCSI 5.77%PRS 67.77
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CSI 2.77rCSI 3.8%PRS 71.84
-
CSI 2.69rCSI 4.6%PRS 92.15
-
CSI 2.65rCSI 3.3%PRS 81.19
-
CSI 2.62rCSI 7.01%PRS 72.12
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CSI 2.62rCSI 9.82%PRS 72.89
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CSI 2.61rCSI 5.86%PRS 63.33
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CSI 2.61rCSI 2.56%PRS 83.01
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CSI 2.58rCSI 4.69%PRS 71.89
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CSI 2.55rCSI 51.84%PRS 70.27
-
CSI 2.52rCSI 51.22%PRS 71.41
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CSI 2.51rCSI 60.08%PRS 60.82
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CSI 2.48rCSI 59.88%PRS 61.39
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CSI 2.44rCSI 6.3%PRS 75.8
-
CSI 2.37rCSI 2.94%PRS 78.26
-
CSI 2.37rCSI 3.41%PRS 70.23
-
CSI 2.35rCSI 6.12%PRS 81.02
-
CSI 2.29rCSI 6.64%PRS 69.91
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CSI 2.2rCSI 17.88%PRS 74.65
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CSI 2.18rCSI 1.99%PRS 91.22
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CSI 2.18rCSI 2.61%PRS 78.22
-
CSI 2.1rCSI 1.89%PRS 78.52
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CSI 2.05rCSI 4.08%PRS 76.07
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CSI 0.4rCSI 5.7%PRS 81.3%
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CSI 0.5rCSI 3.0%PRS 75.1%
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CSI 0.5rCSI 4.1%PRS 74.5%
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CSI 0.6rCSI 3.0%PRS 75.1%
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CSI 0.6rCSI 4.1%PRS 73.1%
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CSI 0.7rCSI 1.8%PRS 85.8%
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CSI 0.7rCSI 3.4%PRS 88.2%
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CSI 0.9rCSI 5.3%PRS 72.0%
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CSI 0.9rCSI 3.1%PRS 77.8%
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CSI 1.0rCSI 3.2%PRS 77.0%
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CSI 1.1rCSI 11.1%PRS 76.7%
-
CSI 1.2rCSI 3.8%PRS 82.2%
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CSI 1.2rCSI 3.9%PRS 66.5%
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CSI 1.2rCSI 3.3%PRS 95.2%
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CSI 1.2rCSI 2.7%PRS 87.7%
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CSI 1.3rCSI 2.8%PRS 79.9%
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CSI 1.3rCSI 5.2%PRS 75.7%
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CSI 1.4rCSI 2.6%PRS 87.1%
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CSI 1.4rCSI 12.2%PRS 68.5%
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CSI 1.4rCSI 2.2%PRS 79.5%
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CSI 1.5rCSI 3.8%PRS 75.1%
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CSI 1.5rCSI 2.9%PRS 95.5%
-
CSI 1.5rCSI 3.9%PRS 77.0%
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CSI 1.5rCSI 2.3%PRS 77.2%
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CSI 1.5rCSI 2.1%PRS 82.3%
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CSI 1.5rCSI 6.8%PRS 68.9%
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CSI 1.6rCSI 13.8%PRS 68.7%
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CSI 1.7rCSI 1.9%PRS 84.1%
-
CSI 1.8rCSI 2.9%PRS 81.8%
-
CSI 1.9rCSI 4.3%PRS 80.8%
-
CSI 1.9rCSI 8.5%PRS 64.6%
-
CSI 1.9rCSI 4.8%PRS 80.2%
-
CSI 1.9rCSI 4.9%PRS 70.9%
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CSI 2.1rCSI 4.1%PRS 76.1%
-
CSI 2.1rCSI 1.9%PRS 78.5%
-
CSI 2.2rCSI 2.6%PRS 78.2%
-
CSI 2.2rCSI 2.0%PRS 91.2%
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CSI 2.2rCSI 17.9%PRS 74.7%
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CSI 2.3rCSI 6.6%PRS 69.9%
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CSI 2.4rCSI 6.1%PRS 81.0%
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CSI 2.4rCSI 3.4%PRS 70.2%
-
CSI 2.4rCSI 2.9%PRS 78.3%
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CSI 2.4rCSI 6.3%PRS 75.8%
-
CSI 2.5rCSI 59.9%PRS 61.4%
-
CSI 2.5rCSI 60.1%PRS 60.8%
-
CSI 2.5rCSI 51.2%PRS 71.4%
-
CSI 2.6rCSI 51.8%PRS 70.3%
-
CSI 2.6rCSI 4.7%PRS 71.9%
-
CSI 2.6rCSI 2.6%PRS 83.0%
-
CSI 2.6rCSI 5.9%PRS 63.3%
-
CSI 2.6rCSI 9.8%PRS 72.9%
-
CSI 2.6rCSI 7.0%PRS 72.1%
-
CSI 2.7rCSI 3.3%PRS 81.2%
-
CSI 2.7rCSI 4.6%PRS 92.2%
-
CSI 2.8rCSI 3.8%PRS 71.8%
-
CSI 2.8rCSI 5.8%PRS 67.8%
-
CSI 2.9rCSI 8.0%PRS 75.5%
-
CSI 3.0rCSI 4.0%PRS 86.4%
-
CSI 3.1rCSI 3.0%PRS 73.7%
-
CSI 3.1rCSI 5.5%PRS 75.9%
-
CSI 3.2rCSI 3.6%PRS 72.5%
-
CSI 3.2rCSI 45.3%PRS 71.4%
-
CSI 3.2rCSI 13.2%PRS 72.4%
-
CSI 3.2rCSI 10.8%PRS 64.2%
-
CSI 3.3rCSI 4.8%PRS 73.3%
-
CSI 3.5rCSI 8.3%PRS 67.3%
-
CSI 3.5rCSI 3.1%PRS 85.0%
-
CSI 3.5rCSI 10.3%PRS 81.2%
-
CSI 3.6rCSI 4.9%PRS 72.1%
-
CSI 3.6rCSI 22.7%PRS 72.1%
-
CSI 3.7rCSI 3.4%PRS 81.1%
-
CSI 3.7rCSI 2.9%PRS 69.3%
-
CSI 3.8rCSI 8.7%PRS 68.4%
-
CSI 3.9rCSI 4.2%PRS 82.2%
-
CSI 3.9rCSI 7.0%PRS 73.8%
-
CSI 4.0rCSI 8.7%PRS 68.1%
-
CSI 4.1rCSI 7.1%PRS 72.0%
-
CSI 4.1rCSI 7.7%PRS 68.8%
-
CSI 4.1rCSI 6.1%PRS 80.3%
-
CSI 4.1rCSI 6.8%PRS 69.9%
-
CSI 4.1rCSI 5.3%PRS 76.5%
-
CSI 4.2rCSI 10.2%PRS 72.7%
-
CSI 4.2rCSI 6.7%PRS 73.5%
-
CSI 4.3rCSI 4.5%PRS 83.6%
-
CSI 4.5rCSI 17.8%PRS 87.3%
-
CSI 4.5rCSI 6.2%PRS 80.1%
-
CSI 4.6rCSI 5.8%PRS 85.2%
-
CSI 4.6rCSI 3.6%PRS 92.8%
-
CSI 4.6rCSI 5.9%PRS 70.5%
-
CSI 4.8rCSI 22.8%PRS 80.2%
-
CSI 4.9rCSI 7.7%PRS 71.9%
-
CSI 4.9rCSI 8.7%PRS 61.8%
-
CSI 4.9rCSI 11.3%PRS 71.9%
-
CSI 5.4rCSI 5.3%PRS 74.2%
-
CSI 5.5rCSI 20.8%PRS 71.3%
-
CSI 5.6rCSI 3.7%PRS 91.9%
-
CSI 5.6rCSI 6.8%PRS 86.6%
-
CSI 5.7rCSI 4.2%PRS 74.0%
-
CSI 5.8rCSI 8.0%PRS 78.9%
-
CSI 5.9rCSI 10.4%PRS 74.3%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 2419591172
Symbol: DZIP3_HUMAN
Name: E3 ubiquitin-protein ligase DZIP3
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 12538761
Title: hRUL138, a novel human RNA-binding RING-H2 ubiquitin-protein ligase.
PubMed ID: 12538761
DOI: 10.1242/jcs.00261
PubMed ID: 9734811
Title: Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.
PubMed ID: 9734811
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 12511597
Title: Human Pumilio-2 is expressed in embryonic stem cells and germ cells and interacts with DAZ (Deleted in AZoospermia) and DAZ-like proteins.
PubMed ID: 12511597
Sequence Information:
- Length: 1208
- Mass: 138604
- Checksum: 76945A63AF85207E
- Sequence:
MDSLPDEFFV RHPAVEDQRK EETENKLEKS SGQLNKQEND IPTDLVPVNL LLEVKKLLNA INTLPKGVVP HIKKFLQEDF SFQTMQREVA ANSQNGEEIV PALTLRFLIT QLEAALRNIQ AGNYTAHQIN IGYYLTLLFL YGVALTERGK KEDYTEAENK FLVMKMMIQE NEICENFMSL VYFGRGLLRC AQKRYNGGLL EFHKSLQEIG DKNDHWFDID PTEDEDLPTT FKDLLNNFIK TTESNIMKQT ICSYLDCERS CEADILKNTS YKGFFQLMCS KSCCVYFHKI CWKKFKNLKY PGENDQSFSG KKCLKEGCTG DMVRMLQCDV PGIVKILFEV VRKDEYITIE NLGASYRKLI SLKITDTDIR PKISLKFNTK DEMPIFKLDY NYFYHLLHII IISGTDIVRQ IFDEAMPPPL LKKELLIHKN VLESYYNHLW TNHPLGGSWH LLYPPNKELP QSKQFDLCLL LALIKHLNVF PAPKKGWNME PPSSDISKSA DILRLCKYRD ILLSEILMNG LTESQFNSIW KKVSDILLRL GMMQEDIDKV KENPIENISL DYHQLSVYLG IPVPEIIQRM LSCYQQGIAL QSITGSQRIE IEELQNEEEE LSPPLMEYNI NVKSHPEIQF AEINKDGTSI PSESSTESLK DLQEVKSKQR KKKKTKNKKN KDSKEDQVPY VVEKEEQLRK EQANPHSVSR LIKDDASDVQ EDSAMEDKFY SLDELHILDM IEQGSAGKVT TDYGETEKER LARQRQLYKL HYQCEDFKRQ LRTVTFRWQE NQMQIKKKDK IIASLNQQVA FGINKVSKLQ RQIHAKDNEI KNLKEQLSMK RSQWEMEKHN LESTMKTYVS KLNAETSRAL TAEVYFLQCR RDFGLLHLEQ TEKECLNQLA RVTHMAASNL ESLQLKAAVD SWNAIVADVR NKIAFLRTQY NEQINKVKQG FALSTLPPVQ LPPPPPSPEI LMQQFLGRPL VKESFFRPIL TVPQMPAVCP GVVSATGQPR APLMTGIAWA LPAPVGDAVP PSAGLRSDPS IMNWERITDR LKTAFPQQTR KELTDFLRKL KDAYGKSLSE LTFDEIVCKI SQFIDPKKSQ SQGKSVSNVN CVSPSHSPSQ PDAAQPPKPA WRPLTSQGPA TWEGASNPDE EEEEEEPCVI CHENLSPENL SVLPCAHKFH AQCIRPWLMQ QGTCPTCRLH VLLPEEFPGH PSRQLPKI