Details for: CEP112
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 38.65rCSI 62.16%PRS 75.53
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CSI 25.99rCSI 52.74%PRS 70.13
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CSI 20.25rCSI 49.21%PRS 72.06
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CSI 18.75rCSI 32.44%PRS 82.59
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CSI 17.87rCSI 55.85%PRS 75.78
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CSI 16.73rCSI 34.71%PRS 86.67
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CSI 16.04rCSI 35.43%PRS 77.13
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CSI 15.62rCSI 56.21%PRS 72.3
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CSI 14.93rCSI 70.24%PRS 79.3
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CSI 14.74rCSI 19%PRS 75.51
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CSI 14.22rCSI 16.98%PRS 74.48
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CSI 13.86rCSI 25.96%PRS 79.37
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CSI 13.63rCSI 51.52%PRS 74.65
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CSI 13.34rCSI 18.24%PRS 91.87
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CSI 12.53rCSI 22.08%PRS 84.44
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CSI 11.64rCSI 14.95%PRS 79.92
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CSI 11.17rCSI 19.73%PRS 73.86
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CSI 10.62rCSI 46.68%PRS 83.51
-
CSI 10.21rCSI 12.7%PRS 72.15
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CSI 9.84rCSI 31.48%PRS 86.79
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CSI 9.82rCSI 15.67%PRS 80.9
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CSI 9.7rCSI 9.03%PRS 89.68
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CSI 9.65rCSI 7.62%PRS 80.69
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CSI 9.53rCSI 21.99%PRS 78.92
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CSI 9.29rCSI 26.13%PRS 84.43
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CSI 9.19rCSI 54.08%PRS 74.8
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CSI 8.79rCSI 6.82%PRS 91.41
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CSI 8.63rCSI 17.33%PRS 81.84
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CSI 8.26rCSI 13.14%PRS 83.51
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CSI 8.13rCSI 11.3%PRS 87.05
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CSI 7.94rCSI 6.99%PRS 79.58
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CSI 7.87rCSI 20.34%PRS 85.23
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CSI 7.85rCSI 9.06%PRS 81.38
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CSI 7.75rCSI 20.64%PRS 76.51
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CSI 7.71rCSI 28.89%PRS 83.34
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CSI 7.65rCSI 17.46%PRS 81.52
-
CSI 7.63rCSI 12.5%PRS 80.7
-
CSI 7.54rCSI 23.57%PRS 77.68
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CSI 7.4rCSI 46.22%PRS 81.87
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CSI 7.28rCSI 53.49%PRS 79.13
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CSI 7.14rCSI 10.9%PRS 87.98
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CSI 7.14rCSI 12.51%PRS 84.48
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CSI 7.12rCSI 53.55%PRS 78.36
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CSI 6.92rCSI 7.17%PRS 90.54
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CSI 6.52rCSI 10.49%PRS 80.4
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CSI 6.46rCSI 43.97%PRS 80.7
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CSI 6.37rCSI 13.83%PRS 77.25
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CSI 6.33rCSI 16.91%PRS 82.49
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CSI 6.22rCSI 10.44%PRS 74.34
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CSI 6.19rCSI 11.13%PRS 83.2
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CSI 5.85rCSI 8.29%PRS 86.02
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CSI 5.8rCSI 6.35%PRS 90.07
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CSI 5.71rCSI 4.23%PRS 84.35
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CSI 5.53rCSI 13.21%PRS 77.44
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CSI 5.49rCSI 8.12%PRS 90.59
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CSI 5.38rCSI 13.14%PRS 81.58
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CSI 5.28rCSI 17.36%PRS 76.37
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CSI 5.2rCSI 6.68%PRS 85.16
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CSI 5.15rCSI 12.76%PRS 88.94
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CSI 5.06rCSI 6.93%PRS 80.62
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CSI 4.98rCSI 11.88%PRS 91.01
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CSI 4.91rCSI 12.79%PRS 89.93
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CSI 4.82rCSI 11.49%PRS 88.6
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CSI 4.71rCSI 22.58%PRS 89.19
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CSI 4.65rCSI 9.04%PRS 90.3
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CSI 4.46rCSI 7.12%PRS 91.3
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CSI 4.41rCSI 12.53%PRS 84.67
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CSI 4.24rCSI 23.97%PRS 77.35
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CSI 4.24rCSI 6.08%PRS 80.25
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CSI 4.18rCSI 18.38%PRS 77.72
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CSI 4.13rCSI 9.26%PRS 74.98
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CSI 4.06rCSI 23.4%PRS 85.42
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CSI 3.85rCSI 5.24%PRS 93.58
-
CSI 3.77rCSI 9.57%PRS 81.59
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CSI 3.67rCSI 5.39%PRS 82.93
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CSI 3.66rCSI 5.93%PRS 83.02
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CSI 3.65rCSI 10.06%PRS 85.46
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CSI 3.65rCSI 11.87%PRS 85.81
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CSI 3.53rCSI 6.41%PRS 81.84
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CSI 3.49rCSI 19.06%PRS 85.27
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CSI 3.36rCSI 8.08%PRS 89.93
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CSI 3.3rCSI 13.31%PRS 89.2
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CSI 3.14rCSI 9.27%PRS 87.86
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CSI 3.07rCSI 13.73%PRS 74.01
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CSI 3.05rCSI 14.62%PRS 84.7
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CSI 3.03rCSI 9%PRS 94.54
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CSI 3.02rCSI 4.69%PRS 90.14
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CSI 2.91rCSI 7.57%PRS 88.08
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CSI 2.89rCSI 4.57%PRS 89.53
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CSI 2.77rCSI 5.69%PRS 76.66
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CSI 2.76rCSI 10.8%PRS 70.55
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CSI 2.74rCSI 2.22%PRS 87.91
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CSI 2.72rCSI 9.12%PRS 74.58
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CSI 2.71rCSI 7.16%PRS 92.75
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CSI 2.7rCSI 23.29%PRS 79.71
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CSI 2.67rCSI 8.59%PRS 85.3
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CSI 2.65rCSI 21.53%PRS 85.01
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CSI 2.57rCSI 4.54%PRS 91.6
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CSI 2.56rCSI 7.48%PRS 94.92
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CSI 2.47rCSI 17.44%PRS 82.23
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CSI 0.6rCSI 4.2%PRS 92.2%
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CSI 0.7rCSI 2.3%PRS 84.0%
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CSI 0.7rCSI 5.3%PRS 81.5%
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CSI 0.9rCSI 3.3%PRS 81.5%
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CSI 0.9rCSI 4.5%PRS 89.0%
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CSI 1.0rCSI 10.2%PRS 84.6%
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CSI 1.0rCSI 2.5%PRS 83.3%
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CSI 1.0rCSI 5.0%PRS 93.0%
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CSI 1.0rCSI 7.4%PRS 79.0%
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CSI 1.0rCSI 6.6%PRS 83.1%
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CSI 1.1rCSI 12.3%PRS 76.7%
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CSI 1.1rCSI 9.6%PRS 83.1%
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CSI 1.2rCSI 4.6%PRS 82.7%
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CSI 1.2rCSI 7.2%PRS 80.0%
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CSI 1.3rCSI 5.1%PRS 94.0%
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CSI 1.3rCSI 18.7%PRS 80.7%
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CSI 1.3rCSI 2.5%PRS 93.8%
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CSI 1.4rCSI 7.7%PRS 94.4%
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CSI 1.5rCSI 5.7%PRS 92.4%
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CSI 1.5rCSI 1.7%PRS 82.8%
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CSI 1.5rCSI 3.4%PRS 81.8%
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CSI 1.6rCSI 8.3%PRS 78.7%
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CSI 1.8rCSI 35.9%PRS 79.4%
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CSI 2.0rCSI 3.9%PRS 84.9%
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CSI 2.0rCSI 13.3%PRS 82.5%
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CSI 2.1rCSI 12.8%PRS 68.2%
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CSI 2.1rCSI 41.8%PRS 80.3%
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CSI 2.1rCSI 5.3%PRS 84.6%
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CSI 2.1rCSI 18.8%PRS 92.8%
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CSI 2.2rCSI 6.3%PRS 79.7%
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CSI 2.2rCSI 2.2%PRS 82.9%
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CSI 2.3rCSI 10.1%PRS 89.2%
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CSI 2.3rCSI 20.2%PRS 76.6%
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CSI 2.3rCSI 24.2%PRS 82.9%
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CSI 2.3rCSI 7.2%PRS 91.0%
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CSI 2.4rCSI 56.2%PRS 72.0%
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CSI 2.4rCSI 3.0%PRS 90.6%
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CSI 2.4rCSI 10.8%PRS 94.7%
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CSI 2.4rCSI 6.2%PRS 91.5%
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CSI 2.5rCSI 17.4%PRS 82.2%
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CSI 2.6rCSI 7.5%PRS 94.9%
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CSI 2.6rCSI 4.5%PRS 91.6%
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CSI 2.7rCSI 21.5%PRS 85.0%
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CSI 2.7rCSI 8.6%PRS 85.3%
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CSI 2.7rCSI 23.3%PRS 79.7%
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CSI 2.7rCSI 7.2%PRS 92.8%
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CSI 2.7rCSI 9.1%PRS 74.6%
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CSI 2.7rCSI 2.2%PRS 87.9%
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CSI 2.8rCSI 10.8%PRS 70.6%
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CSI 2.8rCSI 5.7%PRS 76.7%
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CSI 2.9rCSI 4.6%PRS 89.5%
-
CSI 2.9rCSI 7.6%PRS 88.1%
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CSI 3.0rCSI 4.7%PRS 90.1%
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CSI 3.0rCSI 9.0%PRS 94.5%
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CSI 3.1rCSI 14.6%PRS 84.7%
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CSI 3.1rCSI 13.7%PRS 74.0%
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CSI 3.1rCSI 9.3%PRS 87.9%
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CSI 3.3rCSI 13.3%PRS 89.2%
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CSI 3.4rCSI 8.1%PRS 89.9%
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CSI 3.5rCSI 19.1%PRS 85.3%
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CSI 3.5rCSI 6.4%PRS 81.8%
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CSI 3.7rCSI 11.9%PRS 85.8%
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CSI 3.7rCSI 10.1%PRS 85.5%
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CSI 3.7rCSI 5.9%PRS 83.0%
-
CSI 3.7rCSI 5.4%PRS 82.9%
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CSI 3.8rCSI 9.6%PRS 81.6%
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CSI 3.9rCSI 5.2%PRS 93.6%
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CSI 4.1rCSI 23.4%PRS 85.4%
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CSI 4.1rCSI 9.3%PRS 75.0%
-
CSI 4.2rCSI 18.4%PRS 77.7%
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CSI 4.2rCSI 6.1%PRS 80.3%
-
CSI 4.2rCSI 24.0%PRS 77.4%
-
CSI 4.4rCSI 12.5%PRS 84.7%
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CSI 4.5rCSI 7.1%PRS 91.3%
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CSI 4.7rCSI 9.0%PRS 90.3%
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CSI 4.7rCSI 22.6%PRS 89.2%
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CSI 4.8rCSI 11.5%PRS 88.6%
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CSI 4.9rCSI 12.8%PRS 89.9%
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CSI 5.0rCSI 11.9%PRS 91.0%
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CSI 5.1rCSI 6.9%PRS 80.6%
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CSI 5.2rCSI 12.8%PRS 88.9%
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CSI 5.2rCSI 6.7%PRS 85.2%
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CSI 5.3rCSI 17.4%PRS 76.4%
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CSI 5.4rCSI 13.1%PRS 81.6%
-
CSI 5.5rCSI 8.1%PRS 90.6%
-
CSI 5.5rCSI 13.2%PRS 77.4%
-
CSI 5.7rCSI 4.2%PRS 84.4%
-
CSI 5.8rCSI 6.4%PRS 90.1%
-
CSI 5.9rCSI 8.3%PRS 86.0%
-
CSI 6.2rCSI 11.1%PRS 83.2%
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CSI 6.2rCSI 10.4%PRS 74.3%
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CSI 6.3rCSI 16.9%PRS 82.5%
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CSI 6.4rCSI 13.8%PRS 77.3%
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CSI 6.5rCSI 44.0%PRS 80.7%
-
CSI 6.5rCSI 10.5%PRS 80.4%
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CSI 6.9rCSI 7.2%PRS 90.5%
-
CSI 7.1rCSI 53.6%PRS 78.4%
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CSI 7.1rCSI 12.5%PRS 84.5%
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CSI 7.1rCSI 10.9%PRS 88.0%
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CSI 7.3rCSI 53.5%PRS 79.1%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 244970228
Symbol: CE112_HUMAN
Name: Centrosomal protein of 112 kDa
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 16625196
Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
PubMed ID: 16625196
DOI: 10.1038/nature04689
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 21399614
Title: Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.
PubMed ID: 21399614
PubMed ID: 31654588
Title: Loss-of-function mutations in centrosomal protein 112 is associated with human acephalic spermatozoa phenotype.
PubMed ID: 31654588
DOI: 10.1111/cge.13662
Sequence Information:
- Length: 955
- Mass: 112749
- Checksum: 534B56635FD41406
- Sequence:
MEVGSEEEKW EKLDAEFDHF VVDMKPFVLK LPHRTERQRC ALWIRKLCEP SGTGAGIMGR KNRNLYAKLL LHMLKRGALE GPFTHRPEPG TLKILPSYMS IYFDEPNPAR AKGSSPEGLP AWVLGELETS EHKLNESWKL SSGEDNTLVQ SPTDVYSREQ YTGKLRVRSH SLSPTHREDG QNITPKICEV YSKKSPVSLD DSDIEARLNS WNLGIENPRY LRQKPIPVSL MTPKFSLRKS SSFHDDHFLS RIREKELDMK TKMMEAKFHE EKLKLQQKHD ADVQKILERK NNEIEELKTL YRSKQHETEE TIRKLEKKVQ TLIRDCQVIR ETKEDQIAEL KKICEQSTES LNNDWEKKLH NAVAEMEQEK FDLQKQHTEN IQELLEDTNV RLNKMESEYM AQTQSTNHMI KELEARVQQL TGEAENSNLQ RQKLIQEKAE LERCYQITCS ELQEVKARRN TLHKEKDHLV NDYEQNMKLL QTKYDADINL LKQEHALSAS KASSMIEELE QNVCQLKQQL QESELQRKQQ LRDQENKFQM EKSHLKHIYE KKAHDLQSEL DKGKEDTQKK IHKFEEALKE KEEQLTRVTE VQRLQAQQAD AALEEFKRQV ELNSEKVYAE MKEQMEKVEA DLTRSKSLRE KQSKEFLWQL EDIRQRYEQQ IVELKLEHEQ EKTHLLQQHN AEKDSLVRDH EREIENLEKQ LRAANMEHEN QIQEFKKRDA QVIADMEAQV HKLREELINV NSQRKQQLVE LGLLREEEKQ RATREHEIVV NKLKAESEKM KIELKKTHAA ETEMTLEKAN SKLKQIEKEY TQKLAKSSQI IAELQTTISS LKEENSQQQL AAERRLQDVR QKFEDEKKQL IRDNDQAIKV LQDELENRSN QVRCAEKKLQ HKELESQEQI TYIRQEYETK LKGLMPASLR QELEDTISSL KSQVNFLQKR ASILQEELTT YQGRR
Genular Protein ID: 2983794909
Symbol: F5GYE8_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 16625196
Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
PubMed ID: 16625196
DOI: 10.1038/nature04689
Sequence Information:
- Length: 913
- Mass: 107682
- Checksum: 1B66260E22561802
- Sequence:
MEVGSEEEKW EKLDAEFDHF VVDMKPFVLK LPHRTERQRC ALWIRKLCEP SGTGAGIMGR KNRNLYAKLL LHMLKRGALE GPFTHRPEPG TLKILPSYMS IYFDEPNPAR AKGSSPEGLP AWVLGELETS EHKLNESWKL SSGEDNTLVQ SPTDVYSREQ YTGKLRVRSH SLSPTHREDG QNITPKICEV YSKKSPVSLD DSDIEARLNS WNLGLDMKTK MMEAKFHEEK LKLQQKHDAD VQKILERKNN EIEELKTLYR SKQHETEETI RKLEKKVQTL IRDCQVIRET KEDQIAELKK ICEQSTESLN NDWEKKLHNA VAEMEQEKFD LQKQHTENIQ ELLEDTNVRL NKMESEYMAQ TQSTNHMIKE LEARVQQLTG EAENSNLQRQ KLIQEKAELE RCYQITCSEL QEVKARRNTL HKEKDHLVND YEQNMKLLQT KYDADINLLK QEHALSASKA SSMIEELEQN VCQLKQQLQE SELQRKQQLR DQENKFQMEK SHLKHIYEKK AHDLQSELDK GKEDTQKKIH KFEEALKEKE EQLTRVTEVQ RLQAQQADAA LEEFKRQVEL NSEKVYAEMK EQMEKVEADL TRSKSLREKQ SKEFLWQLED IRQRYEQQIV ELKLEHEQEK THLLQQHNAE KDSLVRDHER EIENLEKQLR AANMEHENQI QEFKKRDAQV IADMEAQVHK LREELINVNS QRKQQLVELG LLREEEKQRA TREHEIVVNK LKAESEKMKI ELKKTHAAET EMTLEKANSK LKQIEKEYTQ KLAKSSQIIA ELQTTISSLK EENSQQQLAA ERRLQDVRQK FEDEKKQLIR DNDQAIKVLQ DELENRSNQV RCAEKKLQHK ELESQEQITY IRQEYETKLK GLMPASLRQE LEDTISSLKS QVNFLQKRAS ILQEELTTYQ GRR