Details for: MARCHF1

Gene ID: 55016

Symbol: MARCHF1

Ensembl ID: ENSG00000145416

Description: membrane associated ring-CH-type finger 1

Associated with

Other Information

Genular Protein ID: 1066002566

Symbol: MARH1_HUMAN

Name: E3 ubiquitin-protein ligase MARCHF1

UniProtKB Accession Codes:

Q8TCQ1 D3DP29 Q9NWR0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChEBI 8 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EC 2 EMBL 3 Ensembl 3 ExpressionAtlas 1 GO 18 Gene3D 1 GeneCards 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 RefSeq 3 SAM 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 UniPathway 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 14722266

Title: Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins.

PubMed ID: 14722266

DOI: 10.1128/jvi.78.3.1109-1120.2004

PubMed ID: 17255932

Title: Novel regulation of MHC class II function in B cells.

PubMed ID: 17255932

DOI: 10.1038/sj.emboj.7601556

PubMed ID: 18389477

Title: Interleukin-10-induced MARCH1 mediates intracellular sequestration of MHC class II in monocytes.

PubMed ID: 18389477

DOI: 10.1002/eji.200737902

PubMed ID: 18305173

Title: MHC class II stabilization at the surface of human dendritic cells is the result of maturation-dependent MARCH I down-regulation.

PubMed ID: 18305173

DOI: 10.1073/pnas.0708874105

PubMed ID: 19117940

Title: The HLA-DRalpha chain is modified by polyubiquitination.

PubMed ID: 19117940

DOI: 10.1074/jbc.m805736200

Sequence Information:

  • Length: 289
  • Mass: 32308
  • Checksum: 923E1809AB3D7087
  • Sequence:
    • MLGWCEAIAR NPHRIPNNTR TPEISGDLAD ASQTSTLNEK SPGRSASRSS NISKASSPTT 
GTAPRSQSRL SVCPSTQDIC RICHCEGDEE SPLITPCRCT GTLRFVHQSC LHQWIKSSDT 
RCCELCKYDF IMETKLKPLR KWEKLQMTTS ERRKIFCSVT FHVIAITCVV WSLYVLIDRT 
AEEIKQGNDN GVLEWPFWTK LVVVAIGFTG GLVFMYVQCK VYVQLWRRLK AYNRVIFVQN 
CPDTAKKLEK NFSCNVNTDI KDAVVVPVPQ TGANSLPSAE GGPPEVVSV

Genular Protein ID: 1553200359

Symbol: A8K0Z6_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K0Z6

Database IDs:

ARBA 8 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 DNASU 1 EMBL 2 GO 2 Gene3D 1 Genevisible 1 GenomeRNAi 1 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 4 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 1 SAM 2 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 289
  • Mass: 32368
  • Checksum: 9231F813AB3D709D
  • Sequence:
    • MLGWCEAIAR NPHRIPNNTR TPEISGDLAD ASQTSTLNEK SPGRSASRSS NISKASSPTT 
GTAPRSQSRL SVCPSTQDIC RICHCEGDEE SPLITPCRCT GTLRFVHQSC LHQWIKSSDT 
RCCELCKYDF IMETKLKPLR KWEKLQMTTS ERRKIFCSVT FHVIAITYVV WSLYVLIDRT 
AEEIKQGNDN GVLEWPFWTK LVVVAIGFTG GLVFMYVQCK VYVQLWRRLK AYNRVIFVQN 
CPDTAKKLEK NFSCNVNTDI KDAVVVPVPQ TGANSLPSAE GGPPEVVSV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.